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Query: [R] COG4756 Predicted cation transporter, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MCNVAELFIPDEPIIEVTAVLSAILILVLVLPFKVRIVEENLEAFFFIMGLLGVATIYYYGILPTPDSLIGLFIKAFKTPLAIAHVGPIPIGIVQAVVFFGLVFYFFHKHIYSILASTMEKVGIPVFAFILTFLLGLISSVISVIVTAVILAEIAAALNISRERKVKYVVYASFAVGIGAALTPLGEPLSTIAISKLNAHFTYLIDILGVYIVPGIAVSAVAAAYSLRGEVYREGLVKFVYEESINEILLRGFRVFLFVAALELLGASFTPMVKWYFAQLPSWALYWINTISAVVDNATLTAAEMGPFLTEEQIRSALMSLLISGGMLIPGNIPNIVAAGRLRITMNEWARVGVPFGIALLLAYFIVIEVLDIHITLSFLast
1 -151.000[R] COG4756 Predicted cation transporter  ali  100  1MCNVAELFIPDEPIIEVTAVLSAILILVLVLPFKVRIVEENLEAFFFIMGLLGVATIYYYGILPTPDSLIGLFIKAFKTPLAIAHVGPIPIGIVQAVVFFGLVFYFFHKHIYSILASTMEKVGIPVFAFILTFLLGLISSVISVIVTAVILAEIAAALNISRERKVKYVVYASFAVGIGAALTPLGEPLSTIAISKLNAHFTYLIDILGVYIVPGIAVSAVAAAYSLRGEVYREGLVKFVYEESINEILLRGFRVFLFVAALELLGASFTPMVKWYFAQLPSWALYWINTISAVVDNATLTAAEMGPFLTEEQIRSALMSLLISGGMLIPGNIPNIVAAGRLRITMNEWARVGVPFGIALLLAYFIVIEVLDIHITLSF 379
2 -12.900[P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases  ali follow..  10  2...........TSMILAVFIFLLTLVLVIWQPKNLS------IGWSACGGAVLALIAGVVNFHDVLTVTG--------------------IVWNATLAFVAIILISLILDNIGFFEWAALHMYGVRMFVYVSLLGAIVAALFANDGAALILTPIVRALHFNEKLVFPFIIASGFIADTTSLPFVVSNLVNIVSADYFHITFIDYASRMVVPYLFSLLASIIVLYLFFRKSIPKRYDLTEVKKPVEAAIVFFSIGMYVVVYGVRVLSDVIQAAADQGLFAGTIGMGFIAAILSSIMNNLPIAGTDTHGMMREALIYANVIGSDLGPKITPIGSLATLLWLHVLSISWGTYFKTGIILTIPTLLITLVGLYIWLLIIHSCF 435
3 -12.600[P] COG3067 Na+/H+ antiporter  ali follow..  10  48VAEFIFTLAMALKCYPLLPGGLLAIEAVIIGMTSAAHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMVL---------SLAFCVAAAFL-----SAFLDALTVVAVVISVAVGFYGIYHRVASSRGEENDMLDDSHIDPHKTVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLVCGLLTCMLVEKMRWFGYGETLPEKVRDVLESLPFTALLTVFFSIVAVIIPIIQFVLQASEHAQLTLFYLFNGLLSSISDNVFVGTIAISLKQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSIRLSYGRMVWMALPYTIVLTLIGLLCVEF......... 495
4 -7.200[P] KOG4505 Na+/H+ antiporter  ali follow..  10  8.............ISKPHLAYAIIGGFTSLFMLCSLIIKEKLFLGEATMATATGLIFGPYVAKLFVDYITEELARVLLVVEVFAAGAELPRAYMLRHWRSMFVMLLPVMIFGWLVSTGFMYALIPRLSFLESLAIAACITATDPVLASSIVGKGKFARRVPGHLRNMLLAESGCNDGMAIPFLYLAIYLIIEKPARHAGRDWVCIIILYECTFGCVLIIGVIARKMIKFSERRG------MDRESFLVFYFVLALFCGGIGTIIGVDDLLVSFKTEESHVSNVIDLLLNLSFFVYVGAIMPWPQFHMPHMDLSVWRLVVLAIC---ILIARRIPAVLLFKSFVPDIINWREALF-FGPIGVGALYTCLVARA....... 383
5 -5.230[S] KOG4610 Uncharacterized conserved protein  ali follow..  9  1..............................................................................................................................MAKIISTIKAILTRIIFSAHSLLAIWQVVA---LKSDIIYWALCGPLLLLLLEGIFT---------IMIKKTQEWRWFCPSVFLYLSSIVPAIWLLELDKVARRVGNMTSTNSTVYSPSNYSITWTTLIEQFLMLILIVGRWLLPKGDLTRDQLSQLLLVYIGTAADIIE---FDSYKDDSIAKIGFLVFLTLGIWSWSLMQFTIVLSATRGRRPRGSGSHHKEEWGIVLNVILQDAPFLTFRLLII...... 283
6 -5.210[S] KOG4843 Uncharacterized conserved protein  ali follow..  11  618.................................NGPTLEVRIPAEHVTATNRQVRGGQLWGTDIYTD--SDLVAGYCRPTASPPPPTMQELRTTIRVLPSQDYYSKLRNNVRSRAWGAGIGCSYRVERCYILKKGGGTIELEPSLTHSSTVEPTLAPMAVERSMTTRAAASNAYSISI---VADKGLKKPLFTSARLKGEVLYLETHSCRYELCFAGEKTIKAIQASQQQSSHEAMETDNNNNKSQNHLTNGDK-----------TDSDNSLIDVF--------------------------SRCKKPLPQKLMRSI--------GFPLPADHIEVLEEN-LDWEDVQWSQTGVWIAYTLARVHFLS............ 915
7 -5.160[C] KOG4664 Cytochrome oxidase subunit III and related proteins  ali follow..  13  18............PLTGAIGAMTTVSGMVKWF--------HQYDISLFVLGNIITILT-QWWRDVSREGTYQ----LHTYAVTIGLRWGMILFILSEVLFFVSFFWAFFHSSLSPAIELGASWPPMGIISFNPFQIPLLNTAI-LLASGVTVTWAHHSLMENNHSQTTQGLFFTVLLGIYFTILQAYE-PFTIADSIYGSTFFMATGFHGIHVLIGTTFLLVCLLRHLNNHFSKNHHFGFEAAAWYWHFV-----VWLFLYITIYW.................................................................................................................. 259
8 -5.060[P] KOG1418 Tandem pore domain K+ channel  ali follow..  9  181..........................................................................................LMILGYACLGGYIFLTLEYDQQQLDLEVEKQVRLSESTLLAENLLKYLKQWNCGQSNENRCLELI-TKAFIERSIKVERDIRGEGWRYG--LACIGIPLMLFVLKIFGEHSIKWAQKVRYSIRRCVKRCFRRSKLKRASTIESVASDEMPCEES-QITTFPVKWALFIVFFFMVVCSLIVSFWEKW---------FLTAFYFFFVSLSTIGFGDVIPEHPRTACGNGLLEIKICYISVMINGALKMSGDAVNFP................................... 444
9 -4.500[T] KOG2322 N-methyl-D-aspartate receptor glutamate-binding subunit  ali follow..  8  100...........................................................................................................RVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLTGML--------SSYYNTTSVLLCLGITALVCLSVTVFSF---------------------QTKFDFTSCQGVLFVLLMTLFFSG-------------------------------LILAILLPFQYVPWLHAVYAALGAGVFTLFLA--DTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLF........ 311
10 -4.480[R] KOG2295 C2H2 Zn-finger protein  ali follow..  9  498.............................................................................IDLDKVKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIARGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDI--KLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLGLTGENKDTEGEPIERDEQLISVLDRLVLYLRIVHSV-VRVTNNDVQEYIKIYESKLQQFLTKTV-LGAKDAETEVEKFVQANTQELAKDKW-------LCPLSGKKFKGPEFIRKHIFNK. 834
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 4   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhang Y, Stec B, Godzik A. Between order and disorder in protein structures: analysis of "dual personality" fragments in proteins. Structure. 2007 Sep;15(9):1141-7.