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Query: [A] COG5182 Splicing factor 3b, subunit 2, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MYLLTRPKHCCLDFLLMAEIQTAQNPLKELEKILERNNKQKNKKSRNQVRREKKKLLREKTNSGAKLAEKNSDDKDQLTENNDNLYNDKKSNGNFYDTNKTDSVDGMVYTTIVDSVELDPNDPLIEQFKDVFNRFKADGQEKDFEDTDKGQIMYSDDEILSEGEEDALQKQQEEKLSKKKLRKLKRMTVAQLKMLSEKADVVEWWDVSSLDPLFLTHLKAYPNTVPVPRHWNQKRDYLSGQRGIERQLFELPSYIRATGIVQMRNAVHENEADMPLRQKMRERVQPKMGKLDIDYQKLHDAFFRYQTKPVLTGFGECYFEGKELEADVKEKRPGDISEELREALGIAPGAPPPWLFAMQRYGPPPSYPDLKIPGVNCPIPTGAQWGFHPGGWGKPPVDQFNRPLYGDVFGNVKPRIHAGTGSPVSTQHWGELEEFEEEESSEEEESEDVEYPTEEITERETIEEYQSASEPRSQREDLHAEPLTYFNQSNVEVDNVELRKNTQPSSDAANRDLYQVLPEKSTNISGFMGPQHQYDIPTAEDTLPQKRNAHSMLSSTNKGDVALNQSSNWQDELSELVSEQAMKVGAAKRQKTQSKRDKFRLLast
1 -170.000[A] COG5182 Splicing factor 3b, subunit 2  ali  100  1MYLLTRPKHCCLDFLLMAEIQTAQNPLKELEKILERNNKQKNKKSRNQVRREKKKLLREKTNSGAKLAEKNSDDKDQLTENNDNLYNDKKSNGNFYDTNKTDSVDGMVYTTIVDSVELDPNDPLIEQFKDVFNRFKADGQEKDFEDTDKGQIMYSDDEILSEGEEDALQKQQEEKLSKKKLRKLKRMTVAQLKMLSEKADVVEWWDVSSLDPLFLTHLKAYPNTVPVPRHWNQKRDYLSGQRGIERQLFELPSYIRATGIVQMRNAVHENEADMPLRQKMRERVQPKMGKLDIDYQKLHDAFFRYQTKPVLTGFGECYFEGKELEADVKEKRPGDISEELREALGIAPGAPPPWLFAMQRYGPPPSYPDLKIPGVNCPIPTGAQWGFHPGGWGKPPVDQFNRPLYGDVFGNVKPRIHAGTGSPVSTQHWGELEEFEEEESSEEEESEDVEYPTEEITERETIEEYQSASEPRSQREDLHAEPLTYFNQSNVEVDNVELRKNTQPSSDAANRDLYQVLPEKSTNISGFMGPQHQYDIPTAEDTLPQKRNAHSMLSSTNKGDVALNQSSNWQDELSELVSEQAMKVGAAKRQKTQSKRDKFRL 601
2 -118.000[A] KOG2330 Splicing factor 3b, subunit 2  ali follow..  35  4.................DSTVALVHSVVSNGDVSNGNTSASSKKSREIDRRRRRRKQKKNNKASQADVDASDVSAASESKENT------------------DPQPQIVIEYVPEQAEFE--DGFNDEFKEIFEKFNFREPLASEEDGTKDESEEKEDVKKDSDDDEQDNQNKEKGISNKKKKLQRRMKIAELKQVSARPDVVEVWDATSADPKDIPFLKLYFVFVCMIVILLLDASVFVGKRGIEKQPFHLPDFIAATGIEKIRQAYIEKEDGKKLKQKQRERMQPKMGKMDIDYQVLHDAFFKYQTKPKLSALGDLYFEGKEFEVKLRETKPGFLSNDLKEALGMPEGAPPPWLINMQRYGPPPSYPHLKIPGLNAPIPIGASFGFHAGGWGKPPVDEYGRPLYGDVFGVQQQDPNYEEEPIDKSKHWGDLEEEEEEEEEEEEEQEEEMDEEELEDGTESVDTLS---------RYCYHYAFMSTPTGIETPDAIELRKDQRKEP---DRALYQVLEEKGESVAPLLGTSHTYVIKTGTEKTGAKRVDLLRGQKTDRVDVSLQPEELDPVDLSDMVVEHVQQNSRKRKMKEGKKKKDFKF 669
3 -19.500[S] KOG2673 Uncharacterized conserved protein, contains PSP domain  ali follow..  26  129..................................................................................................................................................................................................................................................................................AYSHSIRECPRPF------DRSAVSNARRQHKRKRNQTP--PSRYYQSLQRGKYDGLKPGSLDAETRKLLGLKELDPPPWLNRMREIGYPPGYFAVGFPGINAPIPEN........................................................................................................................................................................................................................... 278
4 -10.000[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  10  3............................................KKLALKRRGKDSEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQ-------------SSSAEEDEESSDEEDNEEEESTDGEEVEDEEKDSKSKQTDDKPSGSGAASKKALTAELPKRDSSKPEYQDSDTSDE-------EDIRNTV-IPMHWYDEYKHIDAKK-IIKPP-QIDEFLRKIEDPDFWRTVKDPLTGQDVRALIKRIVSGRIPNKDHEEYEPWIEWFTSEVEDHKRSFLPSVSEKKRVSRMVHALKMGWMKTT...................................................................................................................................................................................................................................................................... 297
5 -9.020[R] KOG4264 Nucleo-cytoplasmic protein MLN51  ali follow..  1..MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEAND------------AVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLD--------------------DEDRKNPAY------------IPRHWEHDK-FRED----EQAPKSRQELIALYGY-DIRSAHNPDDIKPRRIRKPRYGSPPQRDP....................................................................................................................................................................................................................................................................................................................... 271
6 -8.490[S] COG5373 Predicted membrane protein  ali follow..  11  19...........................................GGRRSAERLDREIESLKAEIARLAKEGMGEPGPDLATGRPSEAGVPSVAGTEATADGPWSRAR-----------------------------EGAGTSHDESAAGRESGDGAIDGPVAPSAAAARAESLESRIGGRWPVWVGGLALA-VQYSI---------EAGLLSPAVRLTLAAIFGLALG-GEVIRRRDVPAIADRFRNA--MIPGVLTAAGAVTL-------------------------------FGVVYAAYGIYDFIGTGAAFVLL--------VSLATVGLSLLHGQALAGLGLLASLLTPLFVSSGEPRPWVLFGFLAVAWLAT................................................................................................................................................................................................................................ 281
7 -7.650[KLB] COG5406 Nucleosome binding factor SPN, SPT16 subunit  ali follow..  12  437.YFFGEDDSSLEDGVKPRKPPTRGTATISSHKGKTRSETRDLDDSAEKRRVEHQKQLASRKQAEGLQRFAQGSVPSSGIEKPTVKRFESYKRDSQLPQAIGELRILVDYRHISTLKNASKNDEGNFVYLRL--NFVSPGQIGGKKDELPFEDPNAQDMKKAATKRETERKEFADVIEQDKLIEIKNKRPAHINDVYVRPAIIRYQSPLRSDSHIDLLFSNMKHLFFQP-HVHLKAPIMVGKRKTQDVQFYREVSDIQFDETGNKKRKYMYGDEDELEQEQEERRR----------AQLDREFKSFAEKIAEASEGRIELD-RELAFNGVPFRSNVLLQPTTDCL-VQLTDTPFTVITLNEI-PPIHINTIPMEQLDN----------------KEWLDSCDICFYEGPLNLNWTTIMKTVNEDFEEGGWGFLGAPSDDEGDDSVEEVSEYEASDADPSDEEEEESEEYSEDASEEDGYSESEVEDEESGEDWDELERKARQEDAKHDAFEER......................................................................................... 1012
8 -7.500[OT] KOG0505 Myosin phosphatase, regulatory subunit  ali follow..  12  767.................TNTTTAKEMDKNENEEADLDEQSSKRLSIRERRRPKERRRGTTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATLTSRVEEDSNRDYKKLYESALTENQK------------------------KTKLQEAQLELADIKSK-LEKVAQQKQEKTSDRSSVLEM----------------------------EKRE----RRALERKMSEMEEEMKN--LHQLKQIQTLKQMNEQLQAENRARVVARLSE....................................................................................................................................................................................................................................................................................................................... 988
9 -7.180[NU] COG1338 Flagellar biosynthesis pathway, component FliP  ali follow..  14  45................................................................................................................................................................................................QEYSVSLQILLIMTALSFIPAFVMLMTSFTRIIIV--------SILRQALGLQSTPLFLTMFVMAPVFDKINSQALQPNEQIPAQEALQKAEVP-----------LKAFMLAQTRTSDLELFVRLSKRGSPEATPLTILVPAFVTSELKTAFQIGFMIFIPFLMAMGMMMLSPLIISLPFKIMLFVLVDG........................................................................................................................................................................................................................... 240
10 -7.120[R] COG3932 Uncharacterized ABC-type transport system, permease components  ali follow..  11  4...............................................................................................................................................QARFGVKNASRGHRMERPQTVKGKIMAVEFGDSQRSLSDTLTGMIASIRGNTITLRELMIEIGEQGFLLLCALL--TLPFLIPVS--------ILISLAITLNRMPWLPKRILDREI------------ATEKLVPTLRKGAALVSKLD--------------VRPRLN-----------LTEGALMNRFNGLMIMAGGVLLMFPLGLIPLSNTLPGIA---SLGIIQRDGL.................................................................................................................................................................................................................................. 204

FFAS is supported by the NIH grant R01-GM087218-01
1 4 2 0 2 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Functional differentiation of proteins: implications for structural genomics. Structure. 2007 Apr;15(4):405-15.