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Query: [S] COG5254 Predicted membrane protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKCVECGAEVDSLYTYYGRGTSNIRLAQCKNCKQFADKYIELDVVLISMDVILMKPQVYRHLLFNSLSARTFRNLTKCAKVVNFCILISLFNVFLVWSRLEKRAALFPYFTPAQAFLSQPIIRQYLTLLLICLVETTVYQISVVLLLCLTMGWKSWTSASGAVILSSSTRMLPVFMVIWDYDLSIAATVVEWVVLFSNVDALCILTGSRRTFTDSTINSLLast
1 -76.300[S] COG5254 Predicted membrane protein  ali  100  1MKCVECGAEVDSLYTYYGRGTSNIRLAQCKNCKQFADKYIELDVVLISMDVILMKPQVYRHLLFNSLSARTFRNLTKCAKVVNFCILISLFNVFLVWSRLEKRAALFPYFTPAQAFLSQPIIRQYLTLLLICLVETTVYQISVVLLLCLTMGWKSWTSASGAVILSSSTRMLPVFMVIWDYDLSIAATVVEWVVLFSNVDALCILTGSRRTFTDSTINSL 220
2 -76.300[S] KOG3134 Predicted membrane protein  ali follow..  100  1MKCVECGAEVDSLYTYYGRGTSNIRLAQCKNCKQFADKYIELDVVLISMDVILMKPQVYRHLLFNSLSARTFRNLTKCAKVVNFCILISLFNVFLVWSRLEKRAALFPYFTPAQAFLSQPIIRQYLTLLLICLVETTVYQISVVLLLCLTMGWKSWTSASGAVILSSSTRMLPVFMVIWDYDLSIAATVVEWVVLFSNVDALCILTGSRRTFTDSTINSL 220
3 -13.000[O] COG3058 Uncharacterized protein involved in formate dehydrogenase formation  ali follow..  18  227VKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGT----YLKIDLASLVLDARMEQ-EGYARSSIN........................................................................................................................................................... 300
4 -11.000[K] COG5641 GATA Zn-finger-containing transcription factor  ali follow..  20  129PVCKNCLTSTTPLWRRDEHGA-----MLCNACG-----FLKLHGK------ISLKTDVIK----NRKSNTNHA................................................................................................................................................... 187
5 -11.000[C] COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit  ali follow..  19  48..CVSC-HSMQPVYQEYKQSVHFQN-AECHDC------HIPPDIPGMVKRKLEASNDLYQTFIAHS.......................................................................................................................................................... 108
6 -10.800[R] KOG4377 Zn-finger protein  ali follow..  12  404FHCRKCDYVCTDAHRRLHLRQDYVRNAHCVTCDG----------------GVLSRAQLAAHKHRTGFPKQE..................................................................................................................................................... 488
7 -10.100[R] KOG4602 Nanos and related proteins  ali follow..  25  233..CNFCNGESRHVYSSHQLKTPDLRHYVCPVCGATGDKYCPLNG----------QQSLYRRSGRNSAGRRVKR................................................................................................................................................... 308
8 -9.960[S] COG3880 Uncharacterized protein with conserved CXXC pairs  ali follow..  20  1MICQECHERPATFHFTKVVNGEKIEVHICEQCAK.......................................................................................................................................................................................... 34
9 -9.610[O] KOG4275 Predicted E3 ubiquitin ligase  ali follow..  20  1MPCESCGVEFTVFRRKYCANCIASRR--CKRCSVFAQRPLSRT------DLLKLKPKDLIFYLKHISTEGCLEKEELVGLVLT......................................................................................................................................... 86
10 -9.420[L] KOG0851 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins  ali follow..  13  230..CKTCNKKVNHIHAGVHGVNNKGKKPRCDTCKTVVTNVIRYMLYANVMDFLLFDSICSELTVLDGSLDEVVDPENLPEPVKNLIGKTFLFLVWVEKEHISDGKEVYKVWKVLC.......................................................................................................... 356
11 -9.400[K] KOG4577 Transcription factor LIM3, contains LIM and HOX domains  ali follow..  16  29.QCAGCNQHIDKFILKVLDRHWHSSCLKCADCQMQLADYCKEDFFKRF-QVVRKAQDFVYHL.............................................................................................................................................................. 112
12 -9.380[K] KOG1244 Predicted transcription factor Requiem/NEURO-D4  ali follow..  17  293VSCSDCGRTPVMMAAVKTYRWQCIECKCCNICGTSEN-----DDQLLFCD-----DRGY-HM.............................................................................................................................................................. 354
13 -9.370[R] KOG0490 Transcription factor, contains HOX domain  ali follow..  19  4.HCAGCERPILDRFLLNVLDRAHIKCVQCCECKTNLSEYCKNDFFRRF-DLVRKARSKVFHL.............................................................................................................................................................. 87
14 -9.360[C] COG1150 Heterodisulfide reductase, subunit C  ali follow..  12  40.ACYQCGTRTRLIMRKLQLGLVDEVITTCYTCYERCPRGVKIVDAVKAARNLAAKKGYM................................................................................................................................................................. 118
15 -9.310[U] KOG4173 Alpha-SNAP protein  ali follow..  17  80FAC-GCCQVFDAL-DDYEHHYHTLHGNVCSFCKR---AFPSGHLLDAHILILSERQDMYDHMVRMHLYPADFR................................................................................................................................................... 176
16 -9.200[R] COG4888 Uncharacterized Zn ribbon-containing protein  ali follow..  21  22FECPRCGKVSVSVKIK-----DNIATITCGSCGDEANAYSKF------IDMY........................................................................................................................................................................ 73
17 -9.150[TZR] KOG1704 FOG: LIM domain  ali follow..  13  203FQCAQCNDVLADQYMQRANKPSSSSTFSCTTC----RLSFSSDTPH-----MSQGDLHW-HA.............................................................................................................................................................. 262
18 -9.120[S] KOG3277 Uncharacterized conserved protein  ali follow..  12  39YTCKVCNSREGPKTFAKSSYEKGVVIVTCSGCHNIADNFEDFKGKNI--DHLKTRGEAVKRRDTIKNENGIFEI.................................................................................................................................................. 117
19 -9.070[S] KOG3740 Uncharacterized conserved protein  ali follow..  17  272YMCAQCKTDFTCRWREEKSGA-----IMCENCMTTNQK-VEHTSRLAFVKALQQEQEIEQRLL............................................................................................................................................................. 334
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Godzik A. Fold recognition methods. Methods Biochem Anal. 2003;44:525-46. Review.