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Query: [O] COG5264 Vacuolar transporter chaperone, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst DLQEVYSHPEGSAGSRNVYIKRRNQRVLKQNMTPEPSQPSPLVNRLKANEMHPVSEEPEDNREVYRNEHGDHFNFRSIPGLLKPSTYGSFKHHGKTFVTPPHIKKPEIPLRVSGPIKVEAKVWLANERTFLKWLHVVVLLGSLALALYNSAGERLGQAFGVVYTLLAIFIGFYAWKLHAKRSQMIKSRSPAPMTDYWGPLIVGTALAISLIVNMSFALKDAVYQNLIEPDRLLVKLFTLast
1 -87.300[O] COG5264 Vacuolar transporter chaperone  ali  100  1DLQEVYSHPEGSAGSRNVYIKRRNQRVLKQNMTPEPSQPSPLVNRLKANEMHPVSEEPEDNREVYRNEHGDHFNFRSIPGLLKPSTYGSFKHHGKTFVTPPHIKKPEIPLRVSGPIKVEAKVWLANERTFLKWLHVVVLLGSLALALYNSAGERLGQAFGVVYTLLAIFIGFYAWKLHAKRSQMIKSRSPAPMTDYWGPLIVGTALAISLIVNMSFALKDAVYQNLIEPDRLLVKLFT 238
2 -68.000[UO] KOG4580 Component of vacuolar transporter chaperone (Vtc) involved in vacuole fusion  ali follow..  100  1..............................................................................................................RVSGPIKVEAKVWLANERTFLKWLHVVVLLGSLALALYNSAGERLGQAFGVVYTLLAIFIGFYAWKLHAKRSQMIKSRSPAPMTDYWGPLIVGTALAISLIVNMSFALKDAVYQNLIEPDRLLVKLFT 128
3 -36.600[S] COG2149 Predicted membrane protein  ali follow..  17  11......................................................................................................................DYRFSLANERTFLAWIRTSLGFLAAGVGLDQLATPVIRELLALLLCLFAGGLAIYGYLRWLRNEKAMRLKEDLPYTHSLLIISVILMIVAVIVMGLVL...................... 112
4 -10.200[P] COG5036 SPX domain-containing protein involved in vacuolar polyphosphate accumulation  ali follow..  9  477.DIDIRKPATHTFIQGRSQSGTHSSSVSANVLTDSENTPIHADGDNYVDEESRIGSSSTRNDNSTFQTS------DSFQELDERTNLLDISKRKGRDSFVAALNSRLKDIKDSFFLETVPKFEEPTEPTVIYEQKYV..................................................................................................... 606
5 -10.100[C] COG3658 Cytochrome b  ali follow..  18  1...................................................................................................................MKNKTKVWDFPTRLF-HWLLAASLPFMWYSAKTGGDMLQWHTRVGLFILFLLVFRLCWGIWIREYMKNGIPEHVQPGHNPLGALMVVALLAAVSFQVGTGLFAAD.................. 120
6 -10.100[S] COG3610 Uncharacterized conserved protein  ali follow..  11  58.......................................................................................................................................ASSLAGAFVVAILSHFFAKHKKMPITIFNVPGIVPLVPGGLAYQAVRNFVLGDYTEAIGFSVQVTVVAGAIAAGLMLSEVF...................... 138
7 -9.830[C] COG1969 Ni,Fe-hydrogenase I cytochrome b subunit  ali follow..  12  1.............................................................................................................MQQKSDNVVSHYVFEAPVRIW-HWLTVLCMAVLMVTGYF-----LIHFSAGMVFTVVLLMRIYWAFVVWYEIRWYLFLAKRPSADIGHNPIGYFLMSVFMIITGFAL...................... 150
8 -9.080[S] KOG2946 Uncharacterized conserved protein  ali follow..  15  125.....................................................................................................................LGGNISFFQSVCVLGYCLTPVAISLIVCRVILLATTRLLFFLRFVTTTIGFAWATYASFVFLGQSQPPHRKPLAVY-----PIFLFFFIISWLVL.......................... 215
9 -8.860[R] KOG4812 Golgi-associated protein/Nedd4 WW domain-binding protein  ali follow..  6  2DHHQPGTGRYQVLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRD-VGNDGIFMNWLGFCLSICGFGLSLIKWIYFNGQYWLWWIFLVLGLLLFFRGFVNYLRNMSESMAAAHRT.............................................. 236
10 -8.860[K] KOG3766 Polycomb group protein SCM/L(3)MBT (tumor-supressor in Drosophila and humans)  ali follow..  8  702KKRRSSAVDFTAGSGEESEEEDADAMDDDTASEETGSELRDDQTDTSSAEVPSARPRRAVTLRSGSEPVRRPPPERTRRGRGAPAASSAEEGEKCPPTKPEGTEDTKQEEEERLVLESNPLEWTVTD-RFIKLTDCAPLAKIFGQALLLLTLPTVQECMEL----------------------------------KLGPAIKLCHQIERVKVAFYAQYAN.................. 894
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.