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Query: [S] COG5345 Uncharacterized protein conserved in bacteria, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIDRITALIQAGFSAIGKAAGLLVAWLLWPFMAAHGWYSGRNWLIKGPIALIAILLAGFYGYFVWQTQVWTNFDPDYISRYKLAERTVPPGQELPAVTPAAAAGATGVAANTSAPVCQRSAIVDAAVDLTDFNVNQNAWISSMLLYRLGLFGMDWDSTPFLDNKASFQRGVNQAVRRTSVELVDTLGRVRGTSGINNNLQEARGNMQFSEYSWYFGLDPFGPKTPTPSYYRAAIRSFQAFNGELTACKAVFDTRADNLIQFIDRIAGDIGSTSAILRERSENYNGGWFDTRADDRFWFAYGQLYGYYGVLSAAGSDFAQVIRERNLTNLWNDTLSQTRAALRIQPAIISNGEESGWLMPSHLATMGFYVLRVRSNLVELRSVLDRLast
1 -140.000[S] COG5345 Uncharacterized protein conserved in bacteria  ali  100  1MIDRITALIQAGFSAIGKAAGLLVAWLLWPFMAAHGWYSGRNWLIKGPIALIAILLAGFYGYFVWQTQVWTNFDPDYISRYKLAERTVPPGQELPAVTPAAAAGATGVAANTSAPVCQRSAIVDAAVDLTDFNVNQNAWISSMLLYRLGLFGMDWDSTPFLDNKASFQRGVNQAVRRTSVELVDTLGRVRGTSGINNNLQEARGNMQFSEYSWYFGLDPFGPKTPTPSYYRAAIRSFQAFNGELTACKAVFDTRADNLIQFIDRIAGDIGSTSAILRERSENYNGGWFDTRADDRFWFAYGQLYGYYGVLSAAGSDFAQVIRERNLTNLWNDTLSQTRAALRIQPAIISNGEESGWLMPSHLATMGFYVLRVRSNLVELRSVLDR 385
2 -6.640[O] KOG3488 Dolichol phosphate-mannose regulatory protein (DPM2)  ali follow..  17  3LADRAVGLLL-SSISLSIFTYYTFWVIILPFVFIHKYFLPQDYAILVPVFAGIALLSLFIGMVMLKSK............................................................................................................................................................................................................................................................................................................................. 76
3 -6.190[H] COG3201 Nicotinamide mononucleotide transporter  ali follow..  161FWDSTMMVLSIAILMTRKYVENWLIWVVIDVISVAIFAYQGVYAM--ALEYAFLTLIALNGSWLWIKSA............................................................................................................................................................................................................................................................................................................................ 229
4 -6.020[S] COG3898 Uncharacterized membrane-bound protein  ali follow..  12  1MIRLLAFLIV-GFAWLADRPGDMV--VTF-----------NGYQYQVSLMVAAVAIVAVV-MILWWLIRSLWNSPYTISRYFRVRRRDRGYQALSTGMIAAGAGDGALARKKTKEAAKLIRSDQEPLIHL---------LEAQASLLEG-----------HEGARQKFESMLDDPEMRLLGLRGLYLEAERLGDRNAARHYAGRAAAVAPQL----AESTLEELTARGDWDGALKLVDAQKSTRQIERDAANRRRAVLAKAQSLADSDPNAARTAALEANKLQPDFAPAAVAAAAALFKQNDVRKGSKILETAHPEIAELYTHARPGDAVLDRLNRAKKLQEMKK-----NHAESSMTVARAALDAQDFSTARSEAEAAIRM... 358
5 -5.950[R] KOG0553 TPR repeat-containing protein  ali follow..  14  1................................................................................................................................................................MDNKKRLAYAIIQ--------LHDQLRHGGLSSDAQESLEVAIQCLE------AFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICALSSLNKHVEAVAYYKKALELDP........................................ 190
6 -5.900[S] KOG2257 N-acetylglucosaminyltransferase complex, subunit PIG-P, required for phosphatidylinositol biosynthesis  ali follow..  12  15...EVYGFVGSISIVV-----ATVIFLIWGYV---YYYPSKYWAMAMPMYSMVTLLVALVFYIGLNFMSTSKPT....................................................................................................................................................................................................................................................................................................................... 87
7 -5.710[L] COG3923 Primosomal replication protein N``  ali follow..  1...................................................................................................................................................................MVGGMMESYSKFHTILNELKHSAAQFDRQRGEHHRPLFDEVLFHCHGKL----------LTPCVEEAHSTLQALIREKESGRLTALRAEYLSERLLAQIAALTRELSTQNVRRNEPKPHAYFK------------------------KPINELYQELAQHQDWERRLMDLVRDKALLLE------QASATEKAAAQQALLQSEQRLNRCREAKIKIEKRITT 182
8 -5.310[S] KOG4555 TPR repeat-containing protein  ali follow..  11  6.................................................................................................................................................................LTLSPHDQQVLDSIFNPLELSSLQTNNLIPAESDLKDEEPDTQAIKASR-----ELELKAIALSESGELDGALELFQQ---NLAQRASVLNNRA-QTLRLAKRDEEALDDLNKALELANDQQTRTKCHA------HCQRGVLYRKLDNLEAARADFEAAAQAALCNQMLRQAFDQLK............................................... 185
9 -5.220[S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7  ali follow..  315..DLQSACRARGMRAIGVSEERLKEQL-------------VQWL-KVPPALLLLSRTLYLPE---RLKAIVQNLPDGLAETTKQKLTEMEGGQIDHKARIELIRSIESAIANEKKDEEKKKKAAEEALKSKEEAEKAKVQEKEKLVDVAAQAIVHELKKDIYDAVASTSSTTEAKEPAAKPSEAKEEKKEDITVDKKDLSHIEEIIVGGPIK---AKHDILGLREKVLEHKEDLMEINSLDGAFAETKI-----AKRLRHKLNSMIEDVDSMVDKLEDEKRNIREMLIDPTVENSVDLKKEREVRIQDVIDSLAK--GEQADDGEQRERIEALLKTIDE------------DSDGIVDKQLVLEVIELLEKSAAQMASMIGTLKK 682
10 -5.210[D] KOG0995 Centromere-associated protein HEC1  ali follow..  72NGSKIYNFFIACFELIYQHLSQIFKGLGYPYPLKNSYYQPMGSSHGYPHLLDAL----------WLIDI----------------------IRINSAVSEDTQNILFGDFMEQGKAQEKTLNYAWMTSTFR---------------------------DYTNDRKAAENPSSSYWDDTKHRLRKYFEQSNEFEDMTKTAASALEMLNYECDEIEADKGNEASLKEEISRIRDDIRKAKDYLEQNLHVKQHMEKELAMVKSEQEEKISENEKVQDDLKNKIELQKQIHGLTGKERQMNLDNNKDKEVVLEIQSELDRLSKETWKLKDEDFFKEQKSKFIHLAE........................................... 398

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhang Y, Stec B, Godzik A. Between order and disorder in protein structures: analysis of "dual personality" fragments in proteins. Structure. 2007 Sep;15(9):1141-7.