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Query: [S] COG5395 Predicted membrane protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDPHGKSISQASDRWSGLRNAALGVGAATLIVALTAPGAFTDLGAFAQQVRFQPHAPDFSRIAAAPAVVQVHLFSALTALAIGVVLMMRVKGTTLHKLLGWTWVLAMGSTAVSSLFIREINHGAFSFIHLLSGWTIIGLPGAVYAIKRGKVSAHRKAMTGMFVGGLLVAGVFTFLPGRLLWTVFLGLast
1 -85.600[S] COG5395 Predicted membrane protein  ali  100  1MDPHGKSISQASDRWSGLRNAALGVGAATLIVALTAPGAFTDLGAFAQQVRFQPHAPDFSRIAAAPAVVQVHLFSALTALAIGVVLMMRVKGTTLHKLLGWTWVLAMGSTAVSSLFIREINHGAFSFIHLLSGWTIIGLPGAVYAIKRGKVSAHRKAMTGMFVGGLLVAGVFTFLPGRLLWTVFLG 186
2 -11.900[T] KOG2290 Rhomboid family proteins  ali follow..  12  658..................................................................LSLFLH--AGILHCLVSICFQM---LRDLEKLAGWIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVEL----FQSWQILARPWRAFFKLLAVVLFLFTFGLLPW--ISGFISG 779
3 -10.600[S] COG2322 Predicted membrane protein  ali follow..  12  60........................................................................FNSFTFLFLLAALIAIKKGNAVVHKITTSLFLITYVTYHYLS-IMAGIYYFILFTHIILAALIVPLALTAVARAWNQEHERHRKWLYVSLTGVLVYLMISPY............ 184
4 -9.630[T] KOG2289 Rhomboid family proteins  ali follow..  10  115..................................................................SCMWLH--AGIIHLLTNMLSLI---GIRLEQQFGFIYLISGLGGSILSSLFLQESISVGASGALFGLLGAMLSEL----LTNWTIYANKAAALITLLFIIAINLALGMLPR--IGGFLTG 236
5 -9.600[S] KOG2632 Rhomboid family proteins  ali follow..  12  1MRPNIVTEAGVQTRVGQWWNAIPFLTSSVVVVCGVIYLICLLTGYDTFYEVCFLPSAIISRFQVYRFYIIFH--GSLLHVLFNMMALV---GSELERIMGSLTVLLATTNAVLHLLIASLHLMNECAIGFSGILFSMIVIETSLSGVTSRSVFGLFNVPAKLYPWILLIVFQLLMTN--LCGILSG 204
6 -9.300[C] COG2864 Cytochrome b subunit of formate dehydrogenase  ali follow..  13  1MSKIEISNDTRIIRHRTPARISHWMLVICFFMTMFTGVAFF----------FPDFAWLTEILGTPQIARAIHPFTGILMFFAFIYLALLGKYNLGQKMLFWTLNLAMVTLLVTGIIMWRQYFSHYFSIPVLRIAILLHSASAFMLF----ILVH------IYMAFWVKGSIRGIVEGWV....... 193
7 -9.220[R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)  ali follow..  14  142....................................................................IFMHF--SLMHILFNLLWWW---GGAVEKRLGSITVISALLSGYVQQKFSGPWFGGLSGYALMGYVWLRGE-------RDPQSGIYLQRGLIIFALLWIVAGWFDWFGMSMIAGLIVG 261
8 -8.860[T] KOG4293 Predicted membrane protein, contains DoH and Cytochrome b-561/ferric reductase transmembrane domains  ali follow..  13  278......................................................................KHKGLGITILVMGVLQMLRKYWNWYHHNIGRLLIILAISNIFYGIHLAKAGTSWNGGYFAVAVLALTAIGLEVRKFLKKNWKKKKK.............................. 376
9 -8.670[C] COG1969 Ni,Fe-hydrogenase I cytochrome b subunit  ali follow..  9  24................................LTVLCMAVLMVTGYFIGKPLPSVSGEATYLFYMGYIRLIHFSAGMVFTVVLLMRIYRPSADIGHNPIAQAYFLMSVFMIITGFALYSEHSQYAIFAPFRYVVEFFYWTGGNSMDIH---SWHRMWLIGAFVIVYMALREDIMSDDTVISTMVNG 220
10 -8.620[U] COG5102 Membrane protein involved in ER to Golgi transport  ali follow..  13  109........................................................................LAVLGFAIVQGFVAHFRQLTTMERLPITLSYFVTLLATIIATIKIKST---------ILSIVFGVLHILSFVAYLIAFFPFGTRTV--SLGTRMASRSLSNWLP.......... 201
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;