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Query: [T] COG5422 RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLRNGAQNGNINSESHESFGKAAKGFRIFSSFSSSQKLFQRRSSGSITHSPTALSSTTSLNENDGNHFRPASSLSFSPSSLSRKDSGPGDGLEVNKKNNFYRRSSSTDDFGISHARSRKEIQSLGRPHTRQSFSVSDVSNGSSYPNIRKNSVHVNAPMPSFPEGSTAVLLKHHSGSKSASAISNIAPSHSNSTSSRRPYIHPAFLSQVAVEFRKRLNIGDRVKDGLLYKDAFLGSEAVDVLMHIVRTTDRNLALLLGRALDSQKMFHDVTYSHRLRDSLKEVYQYRRIISPPPGLSSMDSNGSSIENNFLYTKRRANTSDSFDSVLSDSSTTPTISSSVQVNSLAFITSSLSAITKEPEAPETEYNPHGVFTLLTECYSSTCSRNRLCYSISCPRRLEQQARLHLKVQPVLSGGSTSITDKQEEDHRLWSENVPKQVVDQIDVREWKRQEIIFEVIYTERDFVRDLEYIRDFWIKPLSTSNVIPENNRQQFIRCVFHNIMQIHAVNSRLSNALNRTQTLQPVVNTIGDLFLDYVPKFEPFIKYGANQAIAKFEFEREKSTNRNFANYVHEVERLRESRKLELNGYLTKPTTRLARYPLLLSGVLKYTDKDNPDTENIPRVIEMIREFLTKLNYETGKTENRLSLLQLNEQLSCSPADRAKLTLFDPSRLLIFKGVVKLKASSYSNGDTENDIHMFLLDNFLLLCKIKIQMKRRVHKLHLRPLPLELLSISYIEDSPSRGSLPRRPSSALLTNPISITKSNPPPVKAYGLQLVFIGARGFSISLYLNTLIARDQWKQHIEKQQDIIRKRHLVFESRGICCQSWFTGNKLLCAVAYDAGRKLLFGTYKGLYISSRKSNNGSCLEPIFKLQLPNISQLDVIEEHNVLLLLAEKILYELPLDALDSVEQINSKSLRRVTGHVSFVKTGFCMQRILVCAVKSTVLNTTLRIYEADRALKNKKTQSLKKPFGNQATLKIFTEVQMPMEALSVHFLKTKLCVGSFKGFDIISLENAVFQSLLNPADTSFRFLEKREDIRPIAMFRLRGEFLLCYSDFAFFVNTNGWKSRQSWMINWEGQPQGCALCYPYILAFEPDFIEIRNAETAELVQIIMGQNIKLLTDGRGLISEGGEILYSTEPIPFSSGENPIVHSLILPPANAAGPALLast
1 -188.000[T] COG5422 RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases  ali  100  1MLRNGAQNGNINSESHESFGKAAKGFRIFSSFSSSQKLFQRRSSGSITHSPTALSSTTSLNENDGNHFRPASSLSFSPSSLSRKDSGPGDGLEVNKKNNFYRRSSSTDDFGISHARSRKEIQSLGRPHTRQSFSVSDVSNGSSYPNIRKNSVHVNAPMPSFPEGSTAVLLKHHSGSKSASAISNIAPSHSNSTSSRRPYIHPAFLSQVAVEFRKRLNIGDRVKDGLLYKDAFLGSEAVDVLMHIVRTTDRNLALLLGRALDSQKMFHDVTYSHRLRDSLKEVYQYRRIISPPPGLSSMDSNGSSIENNFLYTKRRANTSDSFDSVLSDSSTTPTISSSVQVNSLAFITSSLSAITKEPEAPETEYNPHGVFTLLTECYSSTCSRNRLCYSISCPRRLEQQARLHLKVQPVLSGGSTSITDKQEEDHRLWSENVPKQVVDQIDVREWKRQEIIFEVIYTERDFVRDLEYIRDFWIKPLSTSNVIPENNRQQFIRCVFHNIMQIHAVNSRLSNALNRTQTLQPVVNTIGDLFLDYVPKFEPFIKYGANQAIAKFEFEREKSTNRNFANYVHEVERLRESRKLELNGYLTKPTTRLARYPLLLSGVLKYTDKDNPDTENIPRVIEMIREFLTKLNYETGKTENRLSLLQLNEQLSCSPADRAKLTLFDPSRLLIFKGVVKLKASSYSNGDTENDIHMFLLDNFLLLCKIKIQMKRRVHKLHLRPLPLELLSISYIEDSPSRGSLPRRPSSALLTNPISITKSNPPPVKAYGLQLVFIGARGFSISLYLNTLIARDQWKQHIEKQQDIIRKRHLVFESRGICCQSWFTGNKLLCAVAYDAGRKLLFGTYKGLYISSRKSNNGSCLEPIFKLQLPNISQLDVIEEHNVLLLLAEKILYELPLDALDSVEQINSKSLRRVTGHVSFVKTGFCMQRILVCAVKSTVLNTTLRIYEADRALKNKKTQSLKKPFGNQATLKIFTEVQMPMEALSVHFLKTKLCVGSFKGFDIISLENAVFQSLLNPADTSFRFLEKREDIRPIAMFRLRGEFLLCYSDFAFFVNTNGWKSRQSWMINWEGQPQGCALCYPYILAFEPDFIEIRNAETAELVQIIMGQNIKLLTDGRGLISEGGEILYSTEPIPFSSGENPIVHSLILPPANAAGPAL 1158
2 -49.600[T] KOG4424 Predicted Rho/Rac guanine nucleotide exchange factor/faciogenital dysplasia protein 3  ali follow..  18  168........................................................................................................................................................................................................................................................................................................................................................................................................................EERGAETETKVQERENGESPLELEQLDQHHEMKETNEQKLHKIANELLLTERAYVNRLDLLDQVFYCKLLEEA--RGSFPAEMVNKIFSNISSINAFHSKLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEE------DIVNPSNELIKEGQILKLAA---RNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTV-RTRVGIDGMKIVETQNEEYPHT-------------------------------FQVSGKERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRNAIAKDND................................................................................................................................................................................................................................................................................................................................................. 539
3 -48.400[F] KOG2070 Guanine nucleotide exchange factor  ali follow..  16  125.................................................................................................................................................................................................................................................................................................................PSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRGWWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKG--------------------FDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSEKLSSAN----ISYLMGNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKLYLTYCANHPSAVNVLTEHSEELGEF-----ETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVRKRKELELQI--LTEAIRNWEGD----DIKTLGN-VTYMSQVLIQCA---GSEEKNERYLLLFPNVLLMLSASPRMSGFIY---QGKLPTTGMTITKLEDSENHR-----------------------------NAFEISGSMIERILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSH............................................................................................................................................................................................................................................................................................................................................. 579
4 -45.700[T] KOG2996 Rho guanine nucleotide exchange factor VAV3  ali follow..  15  143.............................................................................................................................................................................................................................................................................................................................................................................................................GLPDLIDETLVEDEEDLYDCVYGEDEGGEVYEDLMKAEEAHQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKR--FLTAAE----FDSVFINIPELVKLHRNLMQEIHDSIVNK---QNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKSKEDVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTT-DPTEKANLKLALDAMKDLAQYVNEVKRDNETLREIKQFQLSIENLNQP------VLLFGRPQGDGEIRITT---LDKHTKQERHIFLFDLAVIVCKRKGDN-----YEMKEIIDLQQYKIAN-----------------------NPTTDKENKKWSYGFYLIHTQGQ-NGLEFYCKTKDLKKKWLEQFEMALSNIRPDY............................................................................................................................................................................................................................................................................................................................................................. 508
5 -45.700[T] KOG3524 Predicted guanine nucleotide exchange factor (PEBBLE)  ali follow..  14  314.............................................................................................................................................................................................................................................................................................................................................................................................................KSLRSQNSRSLSSMRDCSVEGPTSLNMTPDYIYSNDDVENSCKSPRQPSKRLRVCMEMVETEKNYLSLLKLVVKFKECEISHNEFMSRSD----VAMMFGKLDPILELHERIFARLTVMSNEANTLLDFAQVWIDAKEEMKAYPQYINSYDTIKRLFDKQDRENSKFHTFCKAKESNPEFHRLKLTDLMVKPVQRLPSVILLLKEMAKKSDSKLKN--NAEEAAKAIDEVLKTANKTREKNDNFISHLSKFTDI-----ENVPPILVAANRMFIRELVVSPIASTSPGLQQFAKMKLFLFHDVLIITKIRSEKNTMQRLARHASF---------------------ASLHSRQRRPYRYIDQIQLNTMRSAFRIRAPDEIAKCLELQQQNGSTKPNVFVWCLIHRDEQGGDID............................................................................................................................................................................................................................................................................................................................................................ 711
6 -42.100[R] KOG3518 Putative guanine nucleotide exchange factor  ali follow..  11  104......SSSTHLGHQEPPAPLVVAGLRDEPDGAQLSRLVQRRSQESQIHGSSSSIASSGSSRRGSNIRILSPNVHRIITHSDIQPVEAVSAEALKQHQQQSQRSPTQGRYIKTGHSGTPPAAGSAPKLKLSHIPLSKITGKLSTQSGSELVSTFDSSNEYLNSVAFAAFEKSKPQDEDRTPTNKSVPGTPFHFDGHPFQGRKLTLPRYDSQQSIKLIEMEQLAATSAQLLHAKPATPGTPATPTPSATKAKEFVCSEPLSPVDIVDTINFDLVAQHMERLTLADPGDLDPRAELIEAVNKTLVNKPLVRSSSAACASTICSSPLLTYARTKSLGAKASTLGGGVPIKLPTAEQLAELEEANKLSAESLDRLTDIKPKFAARLSELARLNNRPLSSSSICSTSSSSSSGSDQLLNGKLMATSYLASVESLAESENELGDQHHPPAMSVLEKTCLEIVDSERSFVEDLGQVIKGYLQDWKERACLRVDELQ----ILFANIEEIYEFNSMLLQRLINTGRD----GRIARCFIDLRDGFDVYTTYCTSYPEAISLL-TKLLQATHTYSLLASTQKL---HRLPLGSYLLKPVQRILKYHLLLDSLRKHC-----DVKEVVEAHVIMRQVAHNIDQVKRKQEQQSRVKELSGILD------LGPELTVLGE-LRQEGLLMEQ--------HNKQRLVLLFATMLIITKQKEDGRL----QFKTYISQNNLMLSEHLPGEPTS-----------------------------FYVIPFDEPRHQIKLTARNRDQKRIWTQHIKG...................................................................................................................................................................................................................................................................................................................................................................... 837
7 -36.000[T] KOG0689 Guanine nucleotide exchange factor for Rho and Rac GTPases  ali follow..  17  180..........................................................................................................................................................................................................................................................................................................................................................................................................NAIEKLVKNKLSLEGSSYRGSLKDPAGCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGV--PEDMRGKDKIVFGNIHQIYDWHKDFLAELEKCIQE----DRLAQLFIKHERKLHIYVWYCQNKPRSEYIVAE-------YDAYFEEVKQE---QRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMM----NLGRLQGFEGTL-------------TAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEENVDNDPCK-----------------------------FAL--NRETSERVVLQAANADIQQAWVQDINQ...................................................................................................................................................................................................................................................................................................................................................................... 526
8 -33.100[T] KOG4269 Rac GTPase-activating protein BCR/ABR  ali follow..  13  37..........................................................................................................................................................................................................................................................................................................................................................................................................QKGPPEGSETMPYIDESPTMSPQLSARSQGRGDGVSPTPPEGLAPGVEAGKGMRKLVLSGFLASEEIYINQLEALLL-PMKPLKATATTSQPVLTQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVT------------------TPKGETRQLVKDGFLVEVSESSRKLR-----HVFLFTDVLLCAKLKKTSAGKHQQYDCK-IPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQK--TIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVHNIPFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKC--QIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVISVVTKRERSK---------------------VP------YIVRQCVEEVEKRGIEEVGIVATDIQAL-DANNKDILLMLSDMDINAIAYFRELPEPLLTDRLYPAFMDPAAKENCMMHLLRSLPDPNLITFL--FLL-------HLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVVLLYYLQ.......... 839
9 -17.200[T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase (MAP4K), germinal center kinase family  ali follow..  9  84........................................................................................................................................................................................................................................................................................................................................................................................................................................LQKLWMEFCGAGSLQDIYQVTGSLSELQISYVCRE---LQGLAYLHSKIHRDIKGANILTLARRLSFIGTPYWMAPEVAAVALK------GGYNELCDIWSLGITAIELAELQPPLFDVMTKSGYQPPRLKEKGKWSAAFHNFIKVTLTKSPKKRPSATKMLSHQVSQPGLNRGLILDLLDKLKNPGKGPSIGDIEDEEPELPPAIPRRIRSTHRSSSLGIPDADCCRRHMEFRKLRGMETRPPANTARLQPPRDLRSSSPRKQLSE------------DDDYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPNSPRPGPPPSTSSPHLTAHSEPSLWNPPSRELDKPPLLPPKKEKMKRKGCALLVKLFNGCPLRIHSTAAWTHPSTKDQHLLLGAEEGIFILNRNDQEAT----LEMLFPSRTTWVYSINNVLMSLSGKTPHLYSHSILGLLERKETRAGNPIA-RKNMVSTKIQDTKGCRACCVAEGAALETSVVLLQWYQPMNK---------------FLLVRQV-LPTPLSVFALLTGPVCIGVSPGFHTVRFGALSCWLGEMSTEH----------RGPVQVTQVEDMVMVLMDGSVKLVTPEGSPVRGLRTIPMTEAVEAVAMVGGQLQAFWKHGVQVWALGSDQLLQELRDPTFRLLGSPRCSGTISPHCNLLLPGSSNSPASASRVAGI............ 830
10 -16.000[U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3  ali follow..  11  15........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PVEVTCLAFQESNQTLLAGGRAGAYTISANRRGFELTNICKSFHKKAVMELKVCQREDLLLCVSDGQLMAHKLSDPEYKVETLIHKVKPVQTFARFSPKTSGDLYVIVSSRKK------LYLFKWGEKDGHKEFIE----------VALDYNPVFLDTPTSIRCVGEMVFFSVRNEYFSMTMQKDKTTTSPSEGSTPEG-LLNFNCQPGIVPMIDRRRVAFVRNEIVVTTDIWGQRPANV--YKFSEVPMQIVYDSPYLVGMSKGRVEVRSIFDGQLVQTMSLPKAMTL............................................. 299
11 -12.000[U] KOG2215 Exocyst complex subunit  ali follow..  11  1......................................................................................................................................................................................................................................................................................................................................................................................................................................................................MLSNEDGLFQTDAFSPSDYIR-----DRLKGVKIGDETRKLRHLRSEMGALNHASQETLKN----------------------NVFRNY---------------------QQFID----------------ASKEISHLEREIYQLTHSLIEQKQVIENLIMMTGDDKSSIHTVSSHSTTTSTTNPIQILMQKMEGIG--------LNNMSTSEKVILYGEMEQFDVETKKPVQ--KCMLILLSHRLIIGNINAAGKYV----MESTLSLNSVAPVNVKDRESGAANAGK--------------------------VLKLLIFPESRCYLCESARIRTLWFDELEQAKREILHKGSLVRQATIRGKRQTVKERKAAASSAIEEKPSFLEEEEDVGDENEERNDNDISWLSELPAELDDCIAHRDLDQAVELIHEWKQCPTKDAVIDIQLQMRENTIVQLLSDDVS---------RPGAVHGGPRAMKKARTLLTQLGRGTYAT------------------DVYLRRRSAMQRSAMRDV----------------------TVSEEPISYVKQLCTLYGNAVSDIANEFRSMPQY-------------YCQVLQWSYELSTLLLIRRHVIEVAPAIWKNVMHTMEDLTAI--GVHLNFE............................................. 501
12 -9.710[TDBLU] COG5032 Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family  ali follow..  8 1197....................................................................................................................................................................................................................................................................................................................................................................................................LPDLSKRVLIPFLTSKYHLTPIPKIDIRYPIYKENVTIHTWMQLFSLKLMEYAHSQNAE------KIFGICSKVVKDQEVNIPCFLLPFLVLNVILTES-ELEVNKVIEEFQLVINQPGPDGLNSVGQQRYTSFVDVFFKIV-DYLNKWRSAIARKENRYMSVEDATSRESSISKVESFLSRFPSK----------TLGIVSLNCGFHARALFYWEQHIRNATAPYAALESDYRVLQEIYAGIDDEIEAVSLNFHDYSFDQQLLYEIIIQKDPENKKAKIGLLNDSFIINDNHEYSKMLNLGIEASWRSLSIDSLKKCLSKSNLESFEAK---LGSIFYQYLRKDSFAELTERLQPLYVDAATAIANTGAHSAYDCYDILSKLHAINDFSRIAETDGIVSDNDIVLRRRLSQVAPYGKFKHQILSTHLVGYEKFENTKKTAEI------EIARISRKNGQFQRAFNAILKAMDLDKPLATIEHAQWWWHQGQHRKAISELNFSLNNNMFDLVDEHEERPKNRKETLGNPLK--------GKVFLKLTKQLGLKDLETYYHKAVEPVNEQSERFLSGELVTRIINEFGRSLYYGTNHIYESMPKLLTLWLDFGAEELRLSKDDREHIISSRKKSLELMNSNRLSMKIPQYF----FLVALSQMISRVCHPNNKVYKEHII------ANVVASYPGLMATIKSTSQKRSLRGKSILNVLHSRK................................................. 1963
13 -9.630[Z] COG5245 Dynein, heavy chain  ali follow..  11 1311........................................................................................................................................................................................................................................................................................................................................................................................................................................KPRHWNMIFRDSLKDVMVLNLTLNEILLTKIIEREFVIEKSLNRIKKFWKE---SSGLKLVREWDVLEQACKEDLEELVSMKASFEQDCLDLESKLTKLSEIQVNWVE-VQFYWLDLYLGENLDIQNFLPLETSK-TSEYKMITTRAFQLDTTIEVSLSTFLERQRRQFPRFYFLLLKIIGSGKHHDQVSKFMKKMFGSIESIIFLEDFITGVRSVEGEVLNLNEKIELKDSIQAQLNILDTEIKLSVFTQFRDCLGQLKDGTDIEV-QAILLSAQVMWTELVE---------------------KCLQTNQFSKYWKEVDMKIKGLLDKLNKSSDNVKKKIEALLVEYLHFNNVIGQLKNCSTKEEALWAKVQKFYQKNDTLDDLNSVFISQSGYLLQYKFE---------------------YIGIPER-----------LIYTPLLL-------IGFATLTDSLHQKYGGCFFGPAGTGKTETVKAF---------GQNLGRVVVVFNCDDSFD--------------QVLSRLLVGITQIGAWGCFDEF-------------NRLDE------KVLSAVSANIQQIQNGLQVGKS-------------ITLLEEETPLSPHTAVFITLNGYNGRSELPENLKKSFREFSMKSP-MILQIMGFEDSKSLAS-KIVHFLE--GLRTLKG----------RNCSPLISEFGEGEKTVVESL............ 1998
14 -9.540[R] COG5307 SEC7 domain proteins  ali follow..  8  2..................................................................................................................................................................................................................................................................................................QDASEPVINMPALPMNSVNEQHDRHEDLPEVGTTSVTKIINDSDNEDDENGMDLGRVASESLEGDAVVSIDINTEDSSLSPAKQENEKSPEGIEQKYQEEDLKDDKKSNETIATPVPDAASRASLEKQKSGLTNLEKSTHVVLIKCIEQLIQIKVCMKNEKMKNLMEQLKPLLQTECQFDFLIVELFQ---YCFESSQDEVMNISLDTISKLASFASSKDKTPASFGPPKSLLQCMVDMVCD------SINDEVVDGNLQLNVVKALSAHGAILLNSVRKLDTIQSVAQASLTQAVTVVYERLRASHLVFRSMCR-SPDKVSNIRSQAMSLHLIYRILEKNSDLFMDPTLQFRVHASRQYI-SRNAVSPVPQVFEVCCDIFYL--MVFSLRAHFK----QEIEVFFREVYFPMLDLKNTSYNQKLRICLNP--LFSISKVTTNGPSETISEDIEEILPSLESSERSSTPFLNTNSASLKSEVVQLTTFSDFQLKLKTLQCVLDILQSLSNWAESGLYLSRRGVSTDEQGFVGDYDALSRSDTPVTNPY------------YNGKQSFEANSHSSSSIALADPSQFESNKQRKKLLRTCINKFNYKPLKMLSENEYVDINDPKAIAE---FLFRADGIDKTTL-YLGEGD-EKSISVMHEFIDCLS------FINLKFVDALRRLQCFRLPGEAQKID--------------RIML-----------------KFSERYMKENPSAFANADTAYILAYSIILLNTDLHSPRIKNKMTKE--------------------DFIKNRGINDGALGFVILKNEIAMKDDQELAAIAPL.................................. 905
15 -9.080[T] KOG0521 Putative GTPase activating proteins (GAPs)  ali follow..  11  12.......................................................................................................................................................................................................................................................................................................................................................................................................................................KDSPRFRQFVSESDIEHLEQRLEKIIKLCNVAVDSGKEYVKNQSAFAMSLWD---QQHFLDNKNAHNALGKLIHCFQEMNKFHTILLDQA-----SRTVLKNLSVFVKDDINQVGHFLKVSEGYDNAIKNAQASKNRPQEMQEAANILSASKSCFQHTALDYVNY-ITLAQKVPSILSTLLDYYQACVTYYHQGFDLCNDFDEFFKNISEDLNALRGDYQQLEKAMQNRHMSVNRYCDS--TNSTSNKIEGYLFKKKSKGFK--TWCRRWFYLSDNQLVYRKRSNEDSFSVME-----EDLRICSVRPVNEGDRR-------------------------------FCFEVISPTKSHILQADSADMLSLWISALQHSIGAAIQHDSTHHSRPQSTNAPNNSLPCDCRSPEPRWASINLGI-SGVHLG---------------VHYSKVRSLTL-ENVKVMMELGNEVVNRYEARIGDDCGLKKPTEQCEIGVREAWIKA-KYVERRFV.................................................................................................................................................................................................................................. 497
16 -9.060[R] COG1204 Superfamily II helicase  ali follow..  9  449....................................................................................................................................................................................................................................................................................................................................................................................................................................................DLENYVFTEGSRLMSNKAVKLPEGSFRRTGKGYEEIHVPAPNDERLVKIKELPEWSHQAFLNTQSLNRIQSHLYPIAFGTDENILLCAPTG----------------AGKTNVAMLCI---------LNELQKHLREDLSFNLQNFKIVYIAPLKALVRLTPYNIRVAELTGDSQLTKQQISET-QIIVTTPEKWDIITRKANDLSYVNLVRLVI------IDEVHLLHDERGPVLESIVARIFRHQEETLEQVRLVGLLPNDVASFLHVDPKKGLFYFDSTYRPCPLKQ----EFIGITEKTPFKRMQTTNEACYEKVMQHAGKNQVLIFVHSRKETAKTARFIRDKALEEETIGHLLRSDAASREILRAEADSTSDENLKDLLPYGFAIHHAGMRREDRQTSEDLFADGTI---------------QVLVSTATLAWGVNLPAHTVIIKEKGIWTELSPQDVLQMLGRAGRPQFDTYGEG-------------IIITAHSELQYYLSLMNPIESQFMRRLADCLNAEVSLGTVRSIEDGV---DWLGYTYLYVRM-LRSPALYSVGPRADLLHSAAILLEKCKLVYNRQSGTLTATELGKVAASYYVTHNSMAIYNRLLMQTTSFIELFR--------------VFSFSDEFIPVREEEKVELAKLLERVPIPIRERLDEPAAKINALLQSYISRQRLDGFALVADM............. 1119
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 2 6 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.