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Query: [O] COG5596 Mitochondrial import inner membrane translocase, subunit TIM22, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSLSGLLPPNLGGNSPNADGNLTPEEKAALQQAKIIGYMNRISESCVFKSSMAGVLGFGLGGIFGMFISSLDLQHIDPKIYEKPFREQIRIQARDMGSRSFSTAKNFGLLGLIYSGSECCIEAFRAKTDIYNAIAAGVFTGGALAVRSGPKAIVLGGAGFGLFSYGIEKYMHWGELast
1 -75.200[O] COG5596 Mitochondrial import inner membrane translocase, subunit TIM22  ali  100  1MSLSGLLPPNLGGNSPNADGNLTPEEKAALQQAKIIGYMNRISESCVFKSSMAGVLGFGLGGIFGMFISSLDLQHIDPKIYEKPFREQIRIQARDMGSRSFSTAKNFGLLGLIYSGSECCIEAFRAKTDIYNAIAAGVFTGGALAVRSGPKAIVLGGAGFGLFSYGIEKYMHWGE 175
2 -59.100[U] KOG3225 Mitochondrial import inner membrane translocase, subunit TIM22  ali follow..  41  1MVYTGFGLEQISPAQKKPYNELTPEEQG----ERGAEMIMNFMTSCPGKSVVSGVTGFALGGVLGLFMASMAYDTPVQQISDLPFRQQMKLQFTDMGKKSYSSAKNFGYIGMIYAGVECVIESLRAKNDIYNGVTAGFFTGAGLAYKAGPQAALMGGAGFAAFSAAIDLYMKSED 197
3 -56.900[U] KOG3324 Mitochondrial import inner membrane translocase, subunit TIM23  ali follow..  17  17...YRQYNPYQQVNLPYRKLYELPTSPEFLFEEEATKKRLTWGENLTFFTGWGYCTGSVLGAFKGTIAGMRAA------ERGESLKIRTNRILNSGGLVARRGGNCLGSVGLMFAAMESGVTYMRDGDGSLTTVIAGLATGVLYRAASGPRSAVVAGAVGGVAALAAVAGRR... 180
4 -55.600[U] KOG1652 Mitochondrial import inner membrane translocase, subunit TIM17  ali follow..  23  1.....................................MEEYAREPCPWRIVDDCGGAFTMGTIGGGIFQAIKGFRN----SPVGVNHRLRGSLTAIKTRAPQLGGSFAVWGGLFSMIDCSMVQVRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAG.... 130
5 -35.900[S] KOG4608 Uncharacterized conserved protein  ali follow..  11  342.SVVAVMEPKVIEHVEIVPMTGWERLKSIYERENSMEK-----DVTFRVVRMSFLGGFLVGGATGYAQARHAYETNNVGRKYLSVKRKIDYAIVRFAKGGFGVGFKCALISGSIVFLATHITAYRDKFASWYFPAISASVGGVFTFPIGLLGSMKAVGLGVTSGLTLSAVV.... 510
6 -9.280[S] KOG4096 Uncharacterized conserved protein  ali follow..  20  16...........................................PSCFTKIRMGLMMGAMIGGATGILLGGFMGFR---------AGMRGKDLLLQTGKTVAQSGGSFG----VFMGVAQGLRYIFFKN------LAG...................................... 90
7 -8.210[C] KOG0768 Mitochondrial carrier protein PET8  ali follow..  113................................................RAIIGAGAGGLAGAFTYVTLLPLDAIKTKLQTKGASQVYSILGFYSGVSAVIVGSTFSSAVYFGTCEFGKSLLSKFPDFPTVLIPPTAGAMGNIISSAIMVPKELITQRMQAGASGRSYQVLLK... 250
8 -8.060[R] KOG1519 Predicted mitochondrial carrier protein  ali follow..  12  38...................................................VGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVLQLRRDG-QKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTAEAICHGIGEYYRGGLSNVLFFGLRGPIKEH.. 210
9 -7.990[C] KOG0751 Mitochondrial aspartate/glutamate carrier protein Aralar/Citrin (contains EF-hand Ca2+-binding domains)  ali follow..  449...................................DYMRDKFTKDGKIPLYGEIIAGGTGGMCQVVFTNPLEIVKIRLQTAGEVQQAGKKIGVFTVLKELGFLG---AIYFPAYAHAKLASADEDGMNSPGTLFASAFIAGVVIKTRLQVAARAGQTTYNGVIDCARKLIKEE.. 609
10 -7.790[U] COG0811 Biopolymer transport proteins  ali follow..  12  129..............................................................................................PFLATVASVSPYIGLFGTVWGIMH-AFMALSGAKQATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLSLRVNAIEQDYG 208

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Shiryaev SA, Ratnikov BI, Chekanov AV, Sikora S, Rozanov DV, Godzik A,Wang J, Smith JW, Huang Z, Lindberg I, Samuel MA, Diamond MS, Strongin AY. Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase. Biochem J. 2006 Jan 15;393(Pt 2):503-11.