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Query: [S] COG5619 Uncharacterized conserved protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNHLALTSYLGTLAEVGFVNEFRQVVPTRTTNITTIEVGDTSKISGDETGADIAEGSTIHYLACLRQAKYSCILFDGSLVQLKYSTCEGRITNHRYLYFPCPAKLDLRSTADETIYDIVDDACLAGALDAPRLGFMRFDFEPPKREQDRRPPGEHPDAHIHIGIGSCRIPLVSPISVDEFFSFLLKFYYAEFWDHQVHGQSRFREPRTILPLEQGFFHFGWIRPTPLast
1 -108.000[S] COG5619 Uncharacterized conserved protein  ali  100  1MNHLALTSYLGTLAEVGFVNEFRQVVPTRTTNITTIEVGDTSKISGDETGADIAEGSTIHYLACLRQAKYSCILFDGSLVQLKYSTCEGRITNHRYLYFPCPAKLDLRSTADETIYDIVDDACLAGALDAPRLGFMRFDFEPPKREQDRRPPGEHPDAHIHIGIGSCRIPLVSPISVDEFFSFLLKFYYAEFWDHQVHGQSRFREPRTILPLEQGFFHFGWIRPTP 226
2 -7.480[T] KOG3589 G protein signaling regulators  ali follow..  8  333....................................................................GMDEALKDPVGREQFLKFLESEFSSENLRFW---LAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLD---SKSYDKTTHNVKEPGRYT---FEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNV.......... 471
3 -6.540[R] KOG4359 Protein kinase C inhibitor-like protein  ali follow..  9  1MAEEQVNRSAGLAPDCEASATAETTVSSVGTCEAAGKSPEPKDYDST------------VFCRIAGRQD--LHCENEDLICFK---DIKPAATHHYLVVPKKHIGNCRTLRKDQVELVENMVTVGKTILERNNFTDFTNV---GFHMPPFCSISH--LHLHV................................................................ 148
4 -6.080[S] KOG2967 Uncharacterized conserved protein  ali follow..  7  26MSKKQLRRQKYKVKWEEKKLVKRAAERIRKKEKRAALKESGDLSKLRKRKDFRTMAQSNSKQRIALDMSFDDLMIEKDQ-QIGWCYTANRHSPDPFQFHVVGFDGPSRKIYDGNEHNLNQDIHLHQEKLENLFKPEEIVY--TSESENVLSDLDDTKVYVEKGFGHAKLPLRRVLTINQVYEILVHYSVHKNWKDALLSIIPERKNAQLKEEVVE........... 270
5 -5.950[U] KOG1691 emp24/gp25L/p24 family of membrane trafficking proteins  ali follow..  8  86.................................................................EAGQFSFTAYENGSYVACITAIDYKPETTLTIDFDWKTGVHSKEWTNVAKKSQVDMMEYQVKTLMDTVISIHEEMYYLREREEEMQELNRST--------NSKMSLVVCLSVAGLQFWHLKTFFEKK.................................. 210
6 -5.910[T] KOG4566 Cytokine-inducible SH2 protein  ali follow..  11  385............................................................YWGPITRWEAEGKLADGSFLLLSLSFRHGKTLHTRIEHSNGRFSFYEQPDVEGHTS----VDLIEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSYL------CRFVIRQYTRPNKMKDYLQEKHY..................................... 535
7 -5.650[S] COG4345 Uncharacterized protein conserved in archaea  ali follow..  7  14..................................................MEKAQENIELYGGHLLKEPNRYEIRTGVVVAARFA---DKLRRTAFAVFGGVVPREEIVRATSELNKKIYEKLISMGVGKLDIVRISVEASIEGGK................................................................................ 106
8 -5.640[S] COG2380 Uncharacterized protein conserved in bacteria  ali follow..  10  106DSLKKSVVKRYFLLRDNVDISQPTIVFLTQTGKLEFKVDRAKKELSPYVNELMANLELWVAQQVYKAKMADLMITDGTLHYVAKAKNLGYVKKHRKIYLYPEHIKVLQELKVGQRTPIIYTWYVKLNENEGITSVARLEV-PAELGLEEAVKLANLTAYL-AEFNDKRAPQN--LIPIKYLENYLRRRLGSQ.................................. 319
9 -5.500[T] KOG3275 Zinc-binding protein of the histidine triad (HIT) family  ali follow..  12  18...........................................................IFGKILRKE--KFIHEDDKCVAFH---DVAPQAPTHFLVIPRKPIAQLSLAEDGDADLLGHLMLVGRKVAKELGLADGYRV-VINNGKHGAQSVYH--LHLHF................................................................ 115
10 -5.330[S] COG1306 Uncharacterized conserved protein  ali follow..  10  287.NKKAVDERFKFIKDSGM----NAVVIDFKDDNGNLTYSSKLSLPNKLRSVKNFIDVPYILKKAKELGIYVIVFKDSKLYYYDNFKHALWNKKTNKPWWVDIFSPATWEYNISIAKEIQSFGVDE----------IQFDYPVSLAISRMNKYEMQPVDALESFLIMAREQLYVPISVDIYVDVISPMFYPSHYTD............................... 518
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.