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Query: [S] COG5642 Uncharacterized conserved protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MESDMLAFGNVADVLGLPVKEVAARSPFGLISRIEDGLPIGALERVAHLLAPGDAQFKYRLIPKATYERRKMAHRLSSDEGTRLARVARVWGLAVDVWQNEEEARDFLFRPHPMIEDKRPIDVVILSEFGAEIAVDILGSLKYGSAALast
1 -73.100[S] COG5642 Uncharacterized conserved protein  ali  100  1MESDMLAFGNVADVLGLPVKEVAARSPFGLISRIEDGLPIGALERVAHLLAPGDAQFKYRLIPKATYERRKMAHRLSSDEGTRLARVARVWGLAVDVWQNEEEARDFLFRPHPMIEDKRPIDVVILSEFGAEIAVDILGSLKYGSAA 147
2 -6.250[S] COG4755 Uncharacterized protein conserved in archaea  ali follow..  1.....................................MESSFIGNLDEWIKLQKNLLTTL---------KDMEKKEKTEDMDRLDLILASRTAFQHMMRTLKAFDQWLQDPM--VIKHMPREMLEDVKNTSWELLQRLLELD..... 94
3 -6.060[K] COG2944 Predicted transcriptional regulator  ali follow..  13  83.....................................LTPSEIKALRENNHVSQPVFAYLNTSESTVQKWETGAKRPSGPALKLLSIVR.......................................................... 135
4 -5.430[R] COG3093 Plasmid maintenance system antidote protein  ali follow..  10  17...........................................VEFLEPMGITSALAEAMGVHRNTVSNLINGGVLTA---PVAIKLAAALGNTPEF---------WLN-----------IQHAVDLWDTRNRYQEEAKFVK..... 93
5 -5.270[DO] KOG1493 Anaphase-promoting complex (APC), subunit 11  ali follow..  35........................QDDHPGILLKTNTRMSITVKKLCGEWKWLQGGEDTCGICRMEFESACNMCKFPGDDC------PLVLGICRHAF-HRHCIDKWIAAPTNQPRAQCPL.......................... 126
6 -5.200[E] COG0509 Glycine cleavage system H protein (lipoate-binding)  ali follow..  11  23...............................GTYTVGITEHAQELLGDMVFVDLPEVGSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYTGGWIFK--IKASDESELESLLDATAYEALLED........... 128
7 -5.010[S] COG5613 Uncharacterized conserved protein  ali follow..  13  110..........................................LGKLVSNLEEVRKDIKIADIQRLHEQNMKKENQEKIKETEENAKQVKKSGIASKIFG-------WLSAIASVIVGAIMVASGVGAVAGAMMVASGVIGM...... 203
8 -4.970[R] COG0431 Predicted flavoprotein  ali follow..  14  33...........................LFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALPL-----SQDLEVPTHPAVAAAREAVLVADAIWGTVKNLLDWLSRALDLSDTRKFVTVSSVANAGHDQLFAIYKDL...... 160
9 -4.920[F] KOG1292 Xanthine/uracil transporters  ali follow..  331...............................HAINRGILAEGLGSLISGL---------PGVGMTTHTENIGVIGVTRVASRWTMVMAGVFLIILGLITKIGALLSTI--PDPLVGGVLASSMAMVVGVAVSNLQTV.......... 427
10 -4.720[J] COG0042 tRNA-dihydrouridine synthase  ali follow..  12  27...................................AGVTDRPFRELCLRYGAGMAVSEMMSCNPALWKTAKSQNRMVHEGESGIRSV-QIAGSDPQLMAEAAQFSVENGAQIIDINMGCPAKKVNKKLAGSALLRY........... 126

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.