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Query: [A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPYLast
1 -88.200[A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily)  ali  100  1MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY 221
2 -55.700[A] KOG4212 RNA-binding protein hnRNP-M  ali follow..  18  59.NRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEVGEVTYVELLMDGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADIKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHG.................... 300
3 -55.500[A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)  ali follow..  27  2.............VRVYIGRLPNRASDRDVEHFFRGYGKLSDVIMKN-----GFGFVDFQDQRDADDAVHDLNGKELCGERVILEFPRRKVGYNEERSGSNRYSRPCSTRFRLVIDNLSTRYSWQDIKDHIRKLGIEPTYSERNVNQAIVCFTSHDDLRDAMNKLQGEDLNGRKLKCTDETRDRSRSRSPRRRSRSRSPTRSRSPPARRRSPGSDRSDR.. 223
4 -55.500[A] KOG4206 Spliceosomal protein snRNP-U1A/U2B  ali follow..  18  2.....LTADIPPNQSIYIQNLNERIKKEELKRLFSQFGRILDVVALKTPKLRGQAWVTFSEVTAAGHAVRQMQNFPFYDKPMRLQYAKAKSDCLAKAEGTPSGQETMPPNNILFIQNLPHETTSMMLQLLFEQYPGFKEIRMAKPGIAFVEYEDDVQASIAMQPLQGFKITPQPMVISFAKK....................................... 232
5 -53.700[AJ] KOG0148 Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)  ali follow..  24  2........EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKK----------DTSNHFHVFVGDLSPQITTEDIKAAFAPFGRISDARVKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQ........................ 188
6 -53.700[R] KOG0118 FOG: RRM domain  ali follow..  16  161.RTSMAQREDVIRRTVYVSDLDQQVTEEQLAGLFVSCGQVVDCRICGDNSVLRFAFIEFTDEEGAMTALN-LSGTMLGFYPVKVLPSKTAIAPVNPTFLPRTEDEREMCARTIYCTNIDKKVTQSDVKIFFESFCGEVYRLRHSTRIAFVEFVMAESAIAALN-CSGVVLGSLPIRVSPSKTPVRPRSPRHPMH........................... 358
7 -53.100[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  18  116SMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAE---EARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPP....................... 320
8 -52.900[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  16  581.AVQKAAPGTEDARTIFVSNLDFTTTEDEIRQAIEGVASIRFARKANSLVHRGFAYVVMENDQKAQQALL-KDRVPVKGRPMFISANDPEKRVGFKFS-------TTLEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRKPKGIAFVDFDTEASAQKCVASGDKLMLRERELEVALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRA.. 797
9 -51.600[K] KOG4210 Nuclear localization sequence binding protein  ali follow..  13  113.EVVKKKKKDENKYGVWIGNLSFDTTKDDLVRFFIAKTKDNEDEKSRAMKNKGFCYMFFKNVEQMKAVLE-LSESHLNGRNMLIKDSENYSGRPD--KDDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMKCKGFAFIDFKNEEGSTNELKDKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNNSSS................... 337
10 -51.400[A] KOG0145 RNA-binding protein ELAV/HU (RRM superfamily)  ali follow..  19  33SPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIR--------------DANLYVSGLPKTMTQKELEQLFSQYGRIITSRIVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQ.............................. 219
11 -50.200[R] KOG0110 RNA-binding protein (RRM superfamily)  ali follow..  14  670....DADDEPEPNTTLFLRNLNFKTVQETVEKHFRHLGSIHTVEIAKRRKSLGYGFIQFKKSSVAEHALKNLQLTHIDGNPVELKRSDRVLKTQDNDGAQRRLASQKKTGTKILVRNIPFQAQYREVRDIFKAFGELRSLRIAHRGFGFVDYMSKAEAKRAFDALSASTLYGRRLVLEWSANDDNQDVEELRKRTAA........................ 881
12 -50.000[K] KOG0147 Transcriptional coactivator CAPER (RRM superfamily)  ali follow..  16  138.PVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRRSKGIAYVEFCEIQSVPLAI-GLTGQRLLGVPIIVQASQAEKNRLA--AMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD................................ 332
13 -49.900[AJ] KOG0123 Polyadenylate-binding protein (RRM superfamily)  ali follow..  16  180..EAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR........................ 385
14 -49.800[A] KOG0120 Splicing factor U2AF, large subunit (RRM superfamily)  ali follow..  15  85.....GSTITRQARRLYVGNIPFGVTEEEMMEFFNQQMHLVGLAQAAGNLDKNFAFLEFRSIDETTQAM-AFDGINLKGQSLKIRRPHDYQPMPGITDTPAISTVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNAQNAANTTQSV........................ 300
15 -47.500[A] KOG0131 Splicing factor 3b, subunit 4  ali follow..  16  13.LLGQHSAERNQDATVYVGGLDAQLSEELLWELFVQAGPVVNVYVPKDNLHQNYGFIEYRSEEDADYAIKVLNMIKLHGKPIRVNKASQDKKSLD-------------VGANLFIGNLDPDVDEKLLYDTFSAFGVIASNPKNSRGFGFISYDSFEASDAAIESMTGQYLSNRQITVSYAYKKDTKGERHGTPAER......................... 205
16 -46.600[A] KOG0144 RNA-binding protein CUGBP1/BRUNO (RRM superfamily)  ali follow..  14  1MNGTHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDR----------KLFIGMISKKCTENDIRVMFSSFGQIEECRILSRGCAFVTFTTRAMAQTAIKAMHQAQTCSSPMVVKFADTQKDKEQKR............................... 196
17 -46.100[A] KOG0146 RNA-binding protein ETR-3 (RRM superfamily)  ali follow..  15  42.NPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDGMHKGCAFLTYCERESALKAQSALHEQKTLPRPIQVKPADSESRGGSSCLRQ-----PPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTINSKGCAFVKYSSHAEAQAAINALHGSQTASSSLVVKFADTDKERTMRRMQQMAGQ........................ 247
18 -44.800[A] KOG1190 Polypyrimidine tract-binding protein  ali follow..  11  48..KGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKG---KNQAFIEMNTEEAANTMVNYYTSVTPRGQPIYIQFSNHKELKTDSSPNQARAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAA. 296
19 -43.600[K] KOG1548 Transcription elongation factor TAT-SF1  ali follow..  14  98.ENSEASPAPVINKAVYIQGLPLDVTVDEIEEVFKKCGVIAKNIDNGTGTPKGDALIVFFRSESVELAEQLFDDTEFRYGSGQKMRVQKANIDYKKEKTVNKDVGGALKKKAVVLKHI--IDLKDDITEEAEKCGRVTNVVLEPDGVVTVRFSNNEEAEACVRLMQGRYFDGRVVEASIYDGKVRFQKSGKHTLDDEEDEEK................... 354
20 -42.500[J] KOG0122 Translation initiation factor 3, subunit g (eIF-3g)  ali follow..  14  102.....EEILLERPRAPGTKADESKATGDGLSQLGKGGAVLMVCRICHKHWTSKCPYKDLAAPTDVFIDKPPTGESSTMSAAPGTGKAAPSMRAGADRSAVGSDMRRRNDENSVRVTNLSEDTREPDLMELFHPFGAVTRVYVVSRGFGFVNFVSREDAQRAINKLNGYGYDNLILRVEWATPRPT.................................... 294
21 -42.000[R] KOG4733 FOG: RRM domain  ali follow..  16  49SSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT---------------------NLYISNLPLSMDEQELENMLKPFGQVISTRITSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPN...................... 235
22 -41.700[A] KOG0121 Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily)  ali follow..  21  18.SRSEQERSLRDSCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMGLDKTPCGFCFVEYYVRSEAEAAMRFVNGTRLDDRLIRVDWDAGFVEGRQYGRGK--------------TGGQVRDEYRTDYDAGRGGYGKLLSQKIAPNTDN......................................................................... 153
23 -41.300[J] KOG0899 Mitochondrial/chloroplast ribosomal protein S19  ali follow..  13  52..SSMLGSLRYMSTKLYIGGLSPGTDEHSLKDAFSSFNGVTEARVMTNGRSRGYGFVNFISEDSANSAISAMNGQELNGFNISVNVAKDWPSLPLSLDESIEEAEKKENKMMFVDAFLMKKKNAALNRKIWSRRSTILPEYVIYNGKTHVRCKITEGVGHKFGEFA....................................................... 232
24 -41.100[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  26  103LMDEVPKKKFTGRCRLFVGNLPNEVKETELKELFSPHGDIAECYLS----GKGFAFLRLDTRAHAESAKEAIDGRIIHGRQVRVRFAVHGA--------------------AIRVKELSPTVSNEMLYHAFSHFGDVERAVHRPTGEGIVEFERKPNCNEAMAAIRDKVFSPKPLICEVLEPRDEDDG................................. 276
25 -40.600[R] KOG0226 RNA-binding proteins  ali follow..  13  86.PALGRLPTMPPVPPSIFMPPQLRAAPIMFPPRVLGIPAPATIEGAPATPAVNAIPQELLRTQALQSDIDKMNFKKQTDPFKKKIKEQQAKKKFVRSGGGQVWEDPDENDFRVFCGDLGNEVSDELLAKAFRKYPSFQKAKVKSKGYGFVSFRDSEDYVRAMREMDGKYVGNRPIKLRKSAWKERNIDVIKQKRKQKKELG.................... 300
26 -40.500[R] KOG0114 Predicted RNA-binding protein (RRM superfamily)  ali follow..  22  3.KRNHIRLPPEVNRLLYVRNLPYKITSDEMYDIFGKFGAIRQIRVGNTPETRGTAFVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYQSNKAFKRVDMDKKQEELNNIKA............................................................................................................... 111
27 -39.400[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  20  44.PPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLVEYESHRAAAMAAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRG...................... 320
28 -38.500[A] KOG4209 Splicing factor RNPS1, SR protein superfamily  ali follow..  16  65SLLTPEEKAEADAKSVYVGNVDYGATAEEIEQHFHGCGSVSRVTIQCDGHPKGFAYVEFTEKEGMQNAL-AMTDSLLRGRQIKVDPKRTNKPNRPPFRGRGGRGRGNVIVKYVYAGGFRPRGRGARRRPGFAPY....................................................................................... 205
29 -38.500[AR] KOG1365 RNA-binding protein Fusilli, contains RRM domain  ali follow..  9  165.LEDQEVGADGDNVVCRARGLPWQASDHHVAQFFAGLDIVPGLCLSSEGRRNGEVLVQFSSQESRDLALK-RHRNFLLSRYIEVYKAGLDEMHVATGSSTEAMEFVSANAIIVRMRGLPYDCTDAQIRTFFEPLKLTDKILFRPTGDAFVQFETEEDAQQGLLK-HRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEEKKK........ 384
30 -37.400[A] KOG4211 Splicing factor hnRNP-F and related RNA-binding proteins  ali follow..  15  4......GTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIREGRPSGEAFVELESEDEVKLALKK-DRETMGHRYVEVFKSNNV-EMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGQGRSTGEAFVQFASQEIAEKALKK-HKERIGHRYIEIFKSSRAEVRTHYDPPR............................ 199
31 -37.100[R] KOG0130 RNA-binding protein RBM8/Tsunagi (RRM superfamily)  ali follow..  17  61.ELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVKGPKRVKKSE.......................................................................................................................... 161
32 -37.000[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  20  179.DAYRDSRERDDMCTLKIMQVNENADENSLRELLFPFAPIPRVSVVRNGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPKVKE................................................................................................................................ 274
33 -36.800[D] KOG4660 Protein Mei2, essential for commitment to meiosis, and related proteins  ali follow..  17  176....EHPNGEHPSRTLFVRNINSSVEDSELSALFEPFGEIRSLYTA--CKSRGFVMISYYDIRAAHAAMRALQNTLLRKRTLDIHFSIPKENPSEKDMNQG----------TLVIFNVDTTVSNDELLQLFGAYGEIREIRENRRFHRFIEYYDVRDAETALKALNRSEIGGKCIKLELSRPGGARRLSVPSQSQDLERTEVTNFYNQVGSHVANSP.... 378
34 -36.100[A] KOG4207 Predicted splicing factor, SR protein superfamily  ali follow..  25  1MSCGRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPLEKAPRGFAFVRFHDRSDAQDAEAAMDGAVLDERELRVRMARYGRRDLPRSSQEEPRGRSWGGR............................................................................................................... 113
35 -35.700[A] KOG4205 RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1  ali follow..  13  35...DDGSHGSQDPGKMFIGGLSWQTTAENLRDYFGRFGEVNECMVMRDKRARGFGFITFVDPSSVDKVLNN-REHELDGKKIDPKVAFPKRTQAKLVTKTK----------KVFIGGLSATSTLEDMKQYFETYGKVEDAMLRHRGFGFVTFDSDEVADKVCEI-HFHEINGKMVECKKAQPKEVMLPVQLNKSRAAAA...................... 228
36 -35.600[A] KOG0107 Alternative splicing factor SRp20/9G8 (RRM superfamily)  ali follow..  33  2.............SRVYVGNLDPRVTERELEDEFRSFGVIRSVWVARR--PPGYAFLDFEDSRDARDAIREVDGKNGWRVEQSHNRGGGGGRGGGRGGGDGGRGRGGSDL............................................................................................................... 96
37 -34.100[A] KOG0108 mRNA cleavage and polyadenylation factor I complex, subunit RNA15  ali follow..  21  1.......MSMTAGNVVFVGNIPYDVSEQQMTEIFNQVGPVKTFKLVLDGSGKGYGFCEFFDSETTAMAVRKLNNSELGPRKIRVEFPSNDPRRNQSYEYTERTDRYMEQQ............................................................................................................... 106
38 -32.900[R] KOG0125 Ataxin 2-binding protein (RRM superfamily)  ali follow..  9  9QGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTGEHNLTLYGSTQAHGEQSSNSPSTQNGSLTQTEGGAQTDGQQSQTQSSENSES-------KSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANG........................ 203
39 -32.700[AR] KOG0109 RNA-binding protein LARK, contains RRM and retroviral-type Zn-finger domains  ali follow..  14  290.LPPPLPPRGACPDDEAVHQKPAPGHRAGDPLSFQAVGKVLECDIIK-----NYGFVHIEDKTAAEDTIHNLHHYKLHGVNINVEASKNKSKAST----------------KLHVGNISPTCTNQELQAKFEKYGPVIECDI-VKDYVLIHFIHMECCPQARLRTAPGMGDQCGCYQCKKEGHWSKECPVDRTGRVADFTEQCNEQYAAVHTPY....... 481
40 -32.000[R] KOG4208 Nucleolar RNA-binding protein NIFK  ali follow..  16  2........AAFSRSAGPILSLNP-QEDAELQKEVAQCDTVTRFRLSRKGNSKGYAFVEFESEDVAKIVTETMNSYLFGERLLECHFMPPEKKMES.............................................................................................................................. 90
41 -30.900[R] KOG4454 RNA binding protein (RRM superfamily)  ali follow..  25  2..EIKPTPSPPEERTIYVANFSEEVDEELLEELFIQAGPVVKVILRDVDSNAKFALVEFEDELSVLFAIELMNGVRLFNQELQVKPRNGTNQEELYKRKKGEIEERVRSV............................................................................................................... 110
42 -30.300[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali follow..  24  23ADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPK............................................................................................................................... 119
43 -29.600[J] KOG0129 Predicted RNA-binding protein (RRM superfamily)  ali follow..  18  443.SHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAFPPKGYAFLLFQDESSVQALIDA---EEDGKLYLCVSSPTIKDKPVSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRYGGVCYAGIYPKGAGRVAFSNQQSYIAAISA-RFVQLQHGEIDKRVEVKPYVLDDQLCDECQGARCGGKFAPF............... 665
44 -29.400[R] KOG1457 RNA binding protein (contains RRM repeats)  ali follow..  21  80VLFVHELKTRPGVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLT-ARQPVGFVIFDSRAGAEAAKNALNGIRFDPENLRLEFAKANTKMAKSKLMATPNPSNA.................................................................................................................. 188
45 -29.200[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  17  212.DRYSDWNPGVPSNKLAILNMPNDVDNTKITLSLGKCGRTMTKFDKNTKQIRTFAFVEFSNRETAEQWMTDYEGWLTDGRTLAVEYAKGDPAAGSGNKGDDAHMVGMTPCDTLLIRGLPDGINNSLIFDSLGALVCLSSISMESKRFAYLQMKSADEAKMLLNLTYKSPIKDKDVQVSWCR........................................ 439
46 -27.800[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  16  399....ESADRDIAQRNIFVRGFGWDTTQENLKTAFESYGEIEECSVVMDGRGKGYGFVMFKTRKGAREALKRPE-KRMYNRIVVCNLASEKPGKAGKEQDMAEP...................................................................................................................... 499
47 -26.700[A] KOG0533 RRM motif-containing protein  ali follow..  19  62.HGISSRGNDSKVIRVNISNLAPTVISSDLEELFGDYR-LSSVSVNFNGDSLGTGDISLTK-RDAERLVQKFSGVALDGKIMKFAVIDSSNMAGRVDFGNRSRSSPGRSS............................................................................................................... 170
48 -25.700[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  27  222.....EPPEDRNITTLYVGNLPEEITEPELRDQFYQFGEIRSIALVPR---QQCAFVQYTKRNAAELAAERTNKLVIQGRKVSIKWAHSQAKQGTAAKTDRR....................................................................................................................... 316
49 -24.500[R] KOG0149 Predicted RNA-binding protein SEB4 (RRM superfamily)  ali follow..  20  12.HYLNSPFGDTTFTKVFVGGLAWETQSETLRQHFEQYGEILEAVVIADGRSKGYGFVTFRDPEAARRACAD-PTPIIDGRRANCNLASLGRPRPPLPYAV......................................................................................................................... 112
50 -21.500[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  12  593SPRRREEHTDPTRWCVQVTNVPFRMKDEELLEWFSEKVRPAKLTRTSDGNASDRWVAEFSSESLMKRSFG--IRTLCTGRTLRLRYIDNAKADEILKIEDVYGEGKRQMNEELSCNGFPKDVTLEDVVEFFNDY-EPDRNSIVMTGECMLACQNQENARRASMDLDGQKLRNSVISV............................................ 945
51 -21.100[K] KOG2068 MOT2 transcription factor  ali follow..  17  107...........QRNLVYIVGLPLNLADEDLKEYFGQYGKVLKVSMSRTPNNTCSVYITYGKEEEAIRCIQSVHGFILDGKALKACFGTTK................................................................................................................................... 196
52 -21.100[TR] KOG4019 Calcineurin-mediated signaling pathway inhibitor DSCR1  ali follow..  13  2....EEVDLQDLPSATIACHLDPRVFVDGFESLFRTYDKDITFQYFK---SFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDK..................................................................................................................... 103
53 -20.800[K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif)  ali follow..  18  41....KEASKADNRGVCYLSRIPPHMDHVRLRHILAQYGELGRIYLAFRGQRFSEGWVEFAKKSVAKRVADMLNGEQIGGKKKS.......................................................................................................................................... 143
54 -20.600[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  21  159.RLGSLDDGDPQTTNLYVVNLSSKVDENFLLRTFGRFGPIASVKIMEKRRERHCGFVAFMNRADGEAAKEKMQGIIVYEYELKIGWGKVVF.................................................................................................................................. 254
55 -20.000[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  12  79.......................EDFFEDLFEELGKFGEIESLNICDNDHMIGNVYVQFKEEDQAAAALQALQGRFYSGRPIIADFSPVTDFREATCRQYEENNCNRGGYCNFMHVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSERQERDGSRGRRQASPKRGGSPGGGREGSEE.. 276
56 -19.900[T] KOG0116 RasGAP SH3 binding protein rasputin, contains NTF2 and RRM domains  ali follow..  20  265.SSAATIDQQAEGYTIFVANLLMDATPEQLNETFKGFGAITKDGIQYRLKGNCFGFVTFASAEAVKLVLQAESAIRIGNRRVSIEEKRGNNDNGRPAMRNGGYR..................................................................................................................... 372
57 -19.600[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  22  90.PTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRG............................................................................................................... 201
58 -19.400[R] KOG1995 Conserved Zn-finger protein  ali follow..  27  268.QCDADCDDNCDNARIYISNLPPDVTTDELKDLFGGIGQVGRIKQKRKGNYKGDACLAYEDPSAAHSAGGFFNNYEMRGNKISVTMAEKSAPRAPTFDQSF........................................................................................................................ 383
59 -18.700[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  15  394.LSKEEKGRSSCGRNFWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSS............................................................................................................... 505
60 -18.200[R] KOG2135 Proteins containing the RNA recognition motif  ali follow..  16  355..GGFTGAINRDNCTLQVAKIPPENTIAKLNEHFATFGTVDNIQVRYNGEIDS-ALVTYASKFDAGKAYKSPT-PVLNNRFIKVFWHNPGGEGSENATGKPSSPTSPPKPSVVIVRGVTDE-LVTDLMAHMEKFGEVFDHSVKADDDGVFPFRKTGDALKAMA--DGKVLNGVDLEMELKTERIEEIPSTDTNMSADQLLAAIPSNLESDEED........ 714
61 -17.900[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  11  81.SSGSLTPTMNRRYQLYVGNLTWWTTDQDIANSLRDIGDLQEVKFRANGQSKGFSVISLGSESSLRAVLDQLPKKEMHGQAPVVTYPSKQALTQFESLQKTRPVPPPQQN............................................................................................................... 194
62 -17.300[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  25  21.GGGGGGGGGGGTEVIQVTNVSPSASSEQMRTLFGFLGKIDELRLFPPDDSSRVCFVKFHDPDSAVVAQH-LTNTVFVDRALIVVPYAE.................................................................................................................................... 112
63 -17.300[A] KOG1996 mRNA splicing factor  ali follow..  19  299...PLTEILKCPTKVVLLRNMAGEVDEDETKEECEKYGKVGKCVIFEPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACF....................................................................................................................................... 390
64 -17.100[A] KOG4213 RNA-binding protein La  ali follow..  12  102....DEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRHKAFKGSIFVVFDSIESAKKFVETPG-QKYKETDLLIAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRAKEGIILFKEKAKEALGKAKDGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKA.. 345
65 -15.000[J] KOG2314 Translation initiation factor 3, subunit b (eIF-3b)  ali follow..  20  44YQDDQSEFDTGFGNIIVVDHLP-EKLEGVVKKIYNQLGVIKENGLLDTKMTLGYCFIEFNTPQEAQNAKEKSHGYKLDKSHI........................................................................................................................................... 136
66 -14.800[A] KOG4008 rRNA processing protein RRP7  ali follow..  11  39......KKDPSKENSIIVSNIPAFVGEGVVLAIIDQFASFEVEESFVQRSNTLTMSITFDKPEAVIQTLALCQSEEQIQEMADTYVERYDTEQTEARKEAKRKYSEPDEDGWITVTKAKKAAKSVKLKKEDVPLIGGLNNKKKKVDLAYYTFQIKKNRQEKAQELL-KKFEEDRKRITQLKQARN.................................... 257
67 -13.100[R] KOG4198 RNA-binding Ran Zn-finger protein and related proteins  ali follow..  22  240.........AERSKIVHVAGLTNDVTQLELESWFTNHGALWTLKTPEPYKSTGTGFVLFASHEDAADALA-FNGYCLGDRMLEIIPSSTKVLDKASDILIPFPSSKNRPR............................................................................................................... 343
68 -13.000[R] KOG2295 C2H2 Zn-finger protein  ali follow..  13  503.VKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLIALNLDEKFR.................................................................................................. 630
69 -11.600[K] COG5175 Transcriptional repressor  ali follow..  18  135...........QKNLVYVVGINPPVPYEEVEKYFGQYGKINKIVVNRKTPHSN-VYITFGSKDDAARCIAQVDGTYMDGRLIKAAYGTTK................................................................................................................................... 233
70 -11.200[AR] KOG2193 IGF-II mRNA-binding protein IMP, contains RRM and KH domains  ali follow..  24  2.............NKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVK---SGYAFVDCPDEHWAMKAIETFSGVELQGKRLEIEHSVPKKQRSR----------------KIQIRNIPPQLRWEVLDSLLAQYGTVENCE................................................................................ 111
71 -9.940[R] KOG1855 Predicted RNA-binding protein  ali follow..  14  262.PQGPNEIDTLDPSLIPSEELAAEITDA-VEFYFSNESILKDAFLLKHVRRNKEGFVSFKRVREWKVVGDAV-----KSRKIELNDVGTKVRRIEPLPSFDETMPSR----TIVACDLPLDLTIEKVSDLFSPCGEIALIRILKKECALVEYLESSSARDARHLNGPFQ.................................................... 453
72 -9.140[O] KOG0111 Cyclophilin-type peptidyl-prolyl cis-trans isomerase  ali follow..  30  2.........ATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDEKHRGFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKP.................................................................................................................................... 84
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;