current user: public
If you have questions about the server, please let us know.

Query: [R] KOG0126 Predicted RNA-binding protein (RRM superfamily), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350
# Score Template Links and tools%idFirst MNPLTKVKLINELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRLQMHILAGIMGVLKGVVIEVEVGAEINPIGIKGPDAPGRGVLRIPVTVGVTEDFSCTVDLEIIMFFKCSQIQLGGYYFCILast
1 -96.700[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali  100  1MNPLTKVKLINELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRLQMHILAGIMGVLKGVVIEVEVGAEINPIGIKGPDAPGRGVLRIPVTVGVTEDFSCTVDLEIIMFFKCSQIQLGGYYFCI 351
2 -50.700[A] KOG4207 Predicted splicing factor, SR protein superfamily  ali follow..  14  7............................PPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPLEPHTKAPRGFAFVRFHDRSDAQDAEAAMDGAVLDERELRVRMARYGRRDLPRSSQEEPRGRSWGGRYGRRSGSPRGRHRSQSRGPSYSRSRSRSHYGGSRYSLSIYRRSRYSRSPYRRSHYRGSRYGRSPYSRSYSRHHYSRSPYRESRYRRSPYIRSSRSRSPYRRSHSKSGSHSASPSTSKSSS................................................................................................ 233
3 -43.800[A] KOG0108 mRNA cleavage and polyadenylation factor I complex, subunit RNA15  ali follow..  28  2..............................SMTAGNVVFVGNIPYDVSEQQMTEIFNQVGPVKTFKLVLDPETGSGKGYGFCEFFDSETTAMAVRKLNNSELGPRKIRVEFPSNDPRRNQSYEYTERTDRYMEQQNAHES................................................................................................................................................................................................................... 111
4 -42.500[R] KOG0130 RNA-binding protein RBM8/Tsunagi (RRM superfamily)  ali follow..  25  45.......REAIHSYERVRNEDDDELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVKGPKRVKKSEKRRR............................................................................................................................................................................................................................... 165
5 -41.700[R] KOG4454 RNA binding protein (RRM superfamily)  ali follow..  11  2........................EIKPTPSPPEERTIYVANFSEEVDEELLEELFIQAGPVVKVILRDV--RDSNAKFALVEFEDELSVLFAIELMNGVRLFNQELQVKPRNGTNQEELYKRKKGEIEERVRSVAAPDRDGRRDSYRDDRNRNRNGNNRDSWQQQQPPRHHRQYDPLPPPPPPPLMGGSGGHWRSGGERGPPQYSTPQMLPHQHFVNQMMQQQINRSAPPYNGRHQNSTPHRHHDRHGYDRSSSRHHRNDDRRRSAHFLDIRKFQAPPTSWAFGNFQCFFWNLFSKITYLQE................................................ 278
6 -40.800[J] KOG0899 Mitochondrial/chloroplast ribosomal protein S19  ali follow..  20  33MAFCTKLGGHWKQGVNVPVSSMLGSLR-----YMSTKLYIGGLSPGTDEHSLKDAFSSFNGVTEARVMTNKVTGRSRGYGFVNFISEDSANSAISAMNGQELNGFNISVNVAKDWPSLP........................................................................................................................................................................................................................................ 146
7 -39.400[J] KOG0122 Translation initiation factor 3, subunit g (eIF-3g)  ali follow..  21  207.............................RRRNDENSVRVTNLSEDTREPDLMELFHPFGAVTRVYVAIDQKTGVSRGFGFVNFVSREDAQRAINKLNGYGYDNLILRVEWATPRPT.......................................................................................................................................................................................................................................... 294
8 -39.300[A] KOG0121 Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily)  ali follow..  26  18.......................SRSEQERSLRDSCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMGLDKYKKTPCGFCFVEYYVRSEAEAAMRFVNGTRLDDRLIRVDWDAGFVEGRQYGR.................................................................................................................................................................................................................................... 117
9 -39.200[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  18  184............................SRERDDMCTLKIMQVNENADENSLRELLFPFAPIPRVSVVRNKETGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPKVKE......................................................................................................................................................................................................................................... 274
10 -39.000[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  12  71....REKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKKRS-KSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREID................... 397
11 -38.500[A] KOG0107 Alternative splicing factor SRp20/9G8 (RRM superfamily)  ali follow..  10  2...................................SRVYVGNLDPRVTERELEDEFRSFGVIRSVWVARR-----PPGYAFLDFEDSRDARDAIREVDGKNGWRVEQSHNRGGGGGRGGGRGGGDGGRGRGGSDLKCYECGESGHFARECRSRGGSGGRRRSRSRSRSPPRYRKSPTYGGRRSYSPRARSPPPPRRRSPSPRGRNYSRSPPPYRARDEVPYANGNGLKDVRRSRS.................................................................................................................... 196
12 -38.100[R] KOG0226 RNA-binding proteins  ali follow..  18  175.......QQAKKKFVRSGGGQVWEDPSLAEWDENDFRVFCGDLGNEVSDELLAKAFRKYPSFQKAKVVRESRTNKSKGYGFVSFRDSEDYVRAMREMDGKYVGNRPIKLRKSAWKERNIDVIKQKRKQKKE............................................................................................................................................................................................................................ 298
13 -37.000[A] KOG4209 Splicing factor RNPS1, SR protein superfamily  ali follow..  16  43AIQNEMVGHMNLNTSSQSNSSQSLLTPEEKAEADAKSVYVGNVDYGATAEEIEQHFHGCGSVSRVTIQCDRFSGHPKGFAYVEFTEKEGMQNAL-AMTDSLLRGRQIKVDPKRTNKPGMSTTNR................................................................................................................................................................................................................................... 165
14 -36.800[R] KOG4208 Nucleolar RNA-binding protein NIFK  ali follow..  15  2..............................AAFSRSAGPILSLNP-QEDAELQKEVAQCDTVTRFRLSRKKRTGNSKGYAFVEFESEDVAKIVTETMNSYLFGERLLECHFMPPEKKME........................................................................................................................................................................................................................................ 89
15 -36.700[R] KOG0114 Predicted RNA-binding protein (RRM superfamily)  ali follow..  19  1.....................MNKRNHIRLPPEVNRLLYVRNLPYKITSDEMYDIFGKFGAIRQIRV---GNTPETRGTAFVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYQSNKAFKRVDMDKKQEELNNIKA........................................................................................................................................................................................................................ 111
16 -34.800[R] KOG0125 Ataxin 2-binding protein (RRM superfamily)  ali follow..  15  77STQNGSLTQTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNE--RGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVT................................................................................................................................................................................................................................... 198
17 -34.200[A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)  ali follow..  10  4.....................................VYIGRLPNRASDRDVEHFFRGYGKLSDVIM--------KNGFGFVDFQDQRDADDAVHDLNGKELCGERVILEFPRRKVGYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTRFRLVIDNLSTRYSWQDIKDHIRKLGIEPTYSEAHKRNVNQAIVCFTSHDDLRDAMNKLQGEDLNGRKLKCTDETRDRSRSRSPRRRSRSRSPTRSRSPPARRRSPGSDRSDRKSRSASPKKRSDKRARSESKSRSRSGGRRSRSNSPPNRSPSPKKRRDNSSPRSGSAS............................. 280
18 -32.800[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  11  77...........................................HFEDFFEDLFEELGKFGEIESLNICDNL-ADHMIGNVYVQFKEEDQAAAALQALQGRFYSGRPIIADFSPVTDFREATCRQYEENNCNRGGYCNFMHVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSERQERDGSRGRRQASPKRGGSPGGGREGSEERRARIEQWNREREEKEEGGA....................................................................................... 296
19 -31.800[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  23  407..................................QRNIFVRGFGWDTTQENLKTAFESYGEIEECSVVMDKDTGRGKGYGFVMFKTRKGAREALKRPEK-RMYNRIVVCNLASEKPGKA........................................................................................................................................................................................................................................ 490
20 -30.800[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  12  375....SEGADQKMSSPEDDSDTKRLSKEEKGRSSCGRNFWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDGSGEKSKDQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREKRSVVSFDKVKEPRKSRDSESHSRVRERSEREQRMQAQWEREERERLEIARERLAFQRQRLERERMERERLERERMHVEHERRREQERIHREREELRRQQEL..................... 700
21 -30.600[R] KOG0149 Predicted RNA-binding protein SEB4 (RRM superfamily)  ali follow..  26  12.......................HYLNSPFGDTTFTKVFVGGLAWETQSETLRQHFEQYGEILEAVVIADKNTGRSKGYGFVTFRDPEAARRACAD-PTPIIDGRRANCNLASLGRPRPPLPYA................................................................................................................................................................................................................................... 111
22 -30.300[A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily)  ali follow..  24  1......................MSGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNR---HGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRG........................................................................................................................................................................................................................................ 94
23 -30.200[R] KOG1457 RNA binding protein (contains RRM repeats)  ali follow..  14  81.......................LFVHELKTRPGVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLI----KLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENLRLEFAKANTKMAKS...................................................................................................................................................................................................................................... 177
24 -30.000[A] KOG0144 RNA-binding protein CUGBP1/BRUNO (RRM superfamily)  ali follow..  26  387.........................AGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKP....................................................................................................................................................................................................................................... 481
25 -28.300[K] KOG4210 Nuclear localization sequence binding protein  ali follow..  22  232............................MSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEDSGKCKGFAFIDFKNEEGSTNELKDKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNNSSS......................................................................................................................................................................................................................... 337
26 -28.200[A] KOG0145 RNA-binding protein ELAV/HU (RRM superfamily)  ali follow..  23  290............................PGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS........................................................................................................................................................................................................................................ 380
27 -27.900[A] KOG0146 RNA-binding protein ETR-3 (RRM superfamily)  ali follow..  19  9.ANGQADNASLSTNMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPRPIQVKPADSESRGGSSCLRQPPSQDRK........................................................................................................................................................................................................................... 153
28 -27.800[AJ] KOG0148 Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)  ali follow..  22  61.AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPQITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAP........................................................................................................................................................................................................................................ 178
29 -27.500[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  25  187LEQMNSVRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPL........................................................................................................................................................................................................................................ 309
30 -27.300[A] KOG4212 RNA-binding protein hnRNP-M  ali follow..  26  646............................PGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKME--NGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRN............................................................................................................................................................................................................................................. 729
31 -27.300[A] KOG4206 Spliceosomal protein snRNP-U1A/U2B  ali follow..  14  3............................TADIPPNQSIYIQNLNERIKKEELKRLFSQFGRILDVVALK---TPKLRGQAWVTFSEVTAAGHAVRQMQNFPFYDKPMRLQYAKAKS........................................................................................................................................................................................................................................... 91
32 -26.800[A] KOG0533 RRM motif-containing protein  ali follow..  12  71................................SKVIRVNISNLAPTVISSDLEELFGDYR-LSSVSVNFNE-HGDSLGTGDISLTK-RDAERLVQKFSGVALDGKIMKFAVIDSSNMAGRVDFGNRSRSSPGRSSRGFQSGPRRNNGKPEDFLRDGVHAGDIKRGGAGRGGFRKGGRGGARDAKPKKTEAE................................................................................................................................................................ 226
33 -26.500[A] KOG0120 Splicing factor U2AF, large subunit (RRM superfamily)  ali follow..  27  200............................TVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNA........................................................................................................................................................................................................................................ 290
34 -26.200[R] KOG0110 RNA-binding protein (RRM superfamily)  ali follow..  23  333....QPLAPAAVDAGNAKWKHQQDSLSKEDDISESGRIFFRNLAYTTTEEDLRKLFEQFGPVVEVNLPLDKLTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLHLLPSKDIEKNPKE...................................................................................................................................................................................................................................... 449
35 -25.500[K] KOG0147 Transcriptional coactivator CAPER (RRM superfamily)  ali follow..  26  223...........QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGG........................................................................................................................................................................................................................................ 330
36 -25.400[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  13  651.......KDRVPVKGRPMFISANDPEKRVSTTLEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRVTHK-DGKPKGIAFVDFDTEASAQKCVASGDKLMLRERELEVALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRAITNKTPQITARLDAMDVSEGTSTSQPLSNDQ......................................................................................................................................................................... 828
37 -25.200[A] KOG0131 Splicing factor 3b, subunit 4  ali follow..  25  3.............TRIAPGVGANLLGQHSAERNQDATVYVGGLDAQLSEELLWELFVQAGPVVNVYVPKDRVTNLHQNYGFIEYRSEEDADYAIKVLNMIKLHGKPIRVNKASQDKKSLDV...................................................................................................................................................................................................................................... 110
38 -24.500[R] KOG0118 FOG: RRM domain  ali follow..  19  166............................QREDVIRRTVYVSDLDQQVTEEQLAGLFVSCGQVVDCRICGD--PNSVLRFAFIEFTDEEGAMTAL-NLSGTMLGFYPVKVLPSKTAIAPV........................................................................................................................................................................................................................................ 253
39 -24.100[AJ] KOG0123 Polyadenylate-binding protein (RRM superfamily)  ali follow..  23  1.........................MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKS...................................................................................................................................................................................................................................... 96
40 -24.100[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  10  92..................................RYQLYVGNLTWWTTDQDIANSLRDIGDLQEVKFFENRANGQSKGFSVISLGSESSLRAVLDQLPKKEMHGQAPVVTYPSKQALTQFESLQKTRPVPPPQQNGPPRGPAPPSMGGEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPAPPSSQQNFNIIVL............... 702
41 -24.100[A] KOG1190 Polypyrimidine tract-binding protein  ali follow..  16  1MDGIVPDIAVGTKRGSDELFSTKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKG------KNQAFIEMNTEEAANTMVNYYTSVTPRGQPIYIQFSNHKELKTDSSPN................................................................................................................................................................................................................................... 143
42 -24.000[K] KOG1548 Transcription elongation factor TAT-SF1  ali follow..  15  82.......SAEGYPSGSRNKKSKSENSEASPAPVINKAVYIQGLPLDVTVDEIEEVFKKCGVIAKNIDNGTPEDGTPKGDALIVFFRSESVELAEQLFDDTEFRYGSGQKMRVQKANIDY........................................................................................................................................................................................................................................ 200
43 -23.000[R] KOG4733 FOG: RRM domain  ali follow..  16  37..........PSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTN........................................................................................................................................................................................................................................... 142
44 -22.900[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  25  227................................RNITTLYVGNLPEEITEPELRDQFYQFGEIRSIALVPR------QQCAFVQYTKRNAAELAAERTNKLVIQGRKVSIKWAHSQAKQGTAAKT................................................................................................................................................................................................................................... 313
45 -22.400[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  11  33...................................EVIQVTNVSPSASSEQMRTLFGFLGKIDELRLFDDSPLPVSSRVCFVKFHDPDSAVVAQ-HLTNTVFVDRALIVVPYAELKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKE................... 405
46 -21.600[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  16  21RALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCR......................................................................................................................................................................................................................................... 137
47 -21.300[K] KOG2068 MOT2 transcription factor  ali follow..  14  73.ERLASEGNMDRKKIQKSKPKSSDGRKPLTSVRQRNLVYIVGLPLNLADEDLKEYFGQYGKVLKVSMSRTQQFPNNTCSVYITYGKEEEAIRCIQSVHGFILDGKALKACFGTTK............................................................................................................................................................................................................................................ 196
48 -21.000[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  13  167KEAIDG----RIIHGRQVRVRFA---------VHGAAIRVKELSPTVSNEMLYHAFSHFGDVERAVHIVD-EKGRPTGEGIVEFERKPNCNEAMAAIRDKVFSPKPLICEVLEPRDEDDGLAE.................................................................................................................................................................................................................................... 279
49 -20.800[T] KOG0116 RasGAP SH3 binding protein rasputin, contains NTF2 and RRM domains  ali follow..  10  252..........ARESKAPAPVSEHSSAATIDQQAEGYTIFVANLLMDATPEQLNETFKGFGAITKDGIQVRSYRLKGNCFGFVTFASAEAVKLVLQKESAIRIGNRRVSIEEKRGNNDNGRPAMRNGGYRNDNGYRNDGYRPRGNGSNGGRGYGRNGSERRGESRNGEAHNGDGKVHQNGTVEASR...................................................................................................................................................................... 428
50 -20.700[A] KOG4205 RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1  ali follow..  19  9.ATAVATLRETSVDGHEEARLNADSDDGSHGSQDPGKMFIGGLSWQTTAENLRDYFGRFGEVNECMVMRDPATKRARGFGFITFVDPSSVDKVLNN-REHELDGKKIDPKVAFPKRTQAKLVTK................................................................................................................................................................................................................................... 132
51 -20.000[TR] KOG4019 Calcineurin-mediated signaling pathway inhibitor DSCR1  ali follow..  8  1.........................MEEVDLQDLPSATIACHLDPRVFVDGFESLFRTYDKDITFQYF------KSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGS........................................................................................................................................................................................................................................ 93
52 -19.600[K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif)  ali follow..  16  19....SKETMKSQKADRKKKKLKEKLLKEASKADNRGVCYLSRIPPHMDHVRLRHILAQYGELGRIYLAAGGFRGQRFSEGWVEFAKKSVAKRVADMLNGEQIGGKKKS................................................................................................................................................................................................................................................... 143
53 -19.200[R] KOG1995 Conserved Zn-finger protein  ali follow..  16  274.............................DDNCDNARIYISNLPPDVTTDELKDLFGGIGQVGNIKIYTD-EKGNYKGDACLAYEDPSAAHSAGGFFNNYEMRGNKISVTMAEKSAPRA-----------------------------------------------------------------------------------------------------------PTFDQSFIILVGNMSFCNAKFMFLVSEDCLDLVSYWGFALYTHLGMTERMSVSDLIMLSLQTCECRRGGGRGGGGGGYGGGGGDRRRDNYSSGPDRNHHGGNRKL----IFNCKM-------HC. 489
54 -18.600[A] KOG4211 Splicing factor hnRNP-F and related RNA-binding proteins  ali follow..  19  286................................TTGHCVHMRGLPYRATENDIYNFFSPLN-PVRVHIEIGP-DGRVTGEADVEFATHEDAVAAM-SKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGG................................................................................................................................................................................................................... 390
55 -17.100[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  23  865............................KSIGPRGTVLSCNGFPKDVTLEDVVEFFNDYE---SIRIRRGDD-GVMTGECMLACQNQENARRASMDLDGQKLRNSVISV.................................................................................................................................................................................................................................................. 945
56 -16.900[AR] KOG1365 RNA-binding protein Fusilli, contains RRM domain  ali follow..  14  146....ELLEKTHQFVNIEYQPAPILEDQEVGADGDNVVCRARGLPWQASDHHVAQFFAGLDIVPGGIALCLSSEGRRNGEVLVQFSSQESRDLAL-KRHRNFLLSRYIEVYKAGLDEFMH........................................................................................................................................................................................................................................ 259
57 -16.800[D] KOG4660 Protein Mei2, essential for commitment to meiosis, and related proteins  ali follow..  17  235HAAMRALQN-TLLRKRTLDIHFSPKENPSEKDMNQGTLVIFNVDTTVSNDELLQLFGAYGEIREI-----RETPNRRFHRFIEYYDVRDAETALKALNRSEIGGKCIKLELSRPGGARR........................................................................................................................................................................................................................................ 348
58 -16.700[A] KOG1996 mRNA splicing factor  ali follow..  19  306................................CPTKVVLLRNMAGEVDEDETKEECEKYGKVGKCVIFEIPGAPDDAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDK........................................................................................................................................................................................................................................... 395
59 -16.600[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  11  114VEELKREQEIRERRNQDYFDPSGRLGSLDDGDPQTTNLYVVNLSSKVDENFLLRTFGRFGPIASVKIMWPREKRRERHCGFVAFMNRADGEAAKEKMQGIIVYEYELKIGWGKVVFLPS........................................................................................................................................................................................................................................ 257
60 -16.200[AR] KOG0109 RNA-binding protein LARK, contains RRM and retroviral-type Zn-finger domains  ali follow..  10  345.DKTAAEDTIHNLHHYKLHGVNINVEASKNKSKASTKLHVGNISPTCTNQELQAKFEKYGPVIECDIV--------KDYVLIHFIHMECCPQARLRTAPGMGDQCGCYQCKKEGHWSKECPVDRTGRVADFTEQCNEQYAAVHTPYTMGYGESRYYNDAYAALHYYKRYWLLWLPLRPPLPPIVEPRHAAAMLPTVGEGYGYGPESELFQASAATRNSLHDMARYEREHYMDRACFSMAQATVIEPAVGGATGQVRVLHCTTHAEENHLSWWNLEKGWRDLSELDSSVEE--RNGAASVFKKKEWSTQGEENKQDRNGPVTQADHPIPLDLEIIPTPTSKEGQLAIYYLKL 712
61 -16.200[J] KOG2314 Translation initiation factor 3, subunit b (eIF-3b)  ali follow..  15  1MAAVVDIDVLTAQLGINWSDSVYQDDQSEFDTGFGNIIVVDHLPVVPKEK-VKKIYNQLGVIKGLLMPVDPDTKMTLGYCFIEFNTPQEAQNAKEKSHGYKLDKSIFAVNMFDDFDR.......................................................................................................................................................................................................................................... 147
62 -15.000[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  13  342..............SKDQSMELEKLGAHMVGMTPCDTLLIRGLPDGINNSLIFDSLGALVCL---SSISMIKLSESKRFAYLQMKSADEAKMLLNLTYKIRIKDKDVQVSWCRD............................................................................................................................................................................................................................................. 440
63 -14.800[J] KOG0129 Predicted RNA-binding protein (RRM superfamily)  ali follow..  21  444........................HQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAKSYFPPKGYAFLLFQDESSVQALIDA---EEDGKLYLCVSSPTIKDKP......................................................................................................................................................................................................................................... 538
64 -14.400[O] KOG0415 Predicted peptidyl prolyl cis-trans isomerase  ali follow..  19  205.EEIAEELQQREMAEQAQILEMVGDLKDADEVPPENVLFVCKLNPVTTDEDLEIIFSRFGKINNCEIVRDRRSGDSLQYAFIEFDNAKSCEQAFFKMDNVLIDDRRIHVDFSQSVSQNYKYKPKSQQQEAPKRRQSPQRRPEVKRSHQRSPSPRRRRSPSPKKDKKRDYRREPARRRR............................................................................................................................................................................. 381
65 -14.000[S] KOG4610 Uncharacterized conserved protein  ali follow..  10  265...................................................VLNVILQDAPFLTFRL-----------LIIFQYKIINYMNVFFTCKNSLVIILQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS.............................. 523
66 -12.900[R] KOG2135 Proteins containing the RNA recognition motif  ali follow..  10  363................................RDNCTLQVAKIPPENTIAKLNEHFATFGTVDNIQVRYNGEIDS----ALVTYASKFDAGKAYKSPTPV-LNNRFIKV-------------------------------HNPGGEGSENATGKPSSPTSPPKPVEKPKIATVQESKFVSVAAQNYRKQIQDAKERLTKEKSILSTLVQAQNQHNIILDKWMVKQKELLIKARTSTDETDKKNATKLVKHLHKKIKACKEEVDGILLKISEKSMVVDEIAAQIEELKNPQKSDDSTRKRKAGSDGDEPQSKMSSVVIVRGVTDELVTDLMAHMEKFGEVFDHSV....... 641
67 -12.800[R] KOG4198 RNA-binding Ran Zn-finger protein and related proteins  ali follow..  10  237............................SFYAERSKIVHVAGLTNDVTQLELESWFTNHGHPVALWTLKTPEPYKSTGTGFVLFASHEDAADAL-AFNGYCLGDRMLEIIPSSTKVLDKASDILIPFPSSKNRPRPGDSFPGPTHVSAATGSNTFSPDFPYGNSYGNGSSHFIANYGGSVHHSNENTMQSDLQHQNGNNAVNHHHSSRSFGGNVPFRAGDWKCGSEGCGYHNFAKNVCCLRCGASRATAAVVADHASGPVNGSYSHNSYSHIPPVMSTSPPNHSVYPYSQLSINSVTANHGQNFGGQNGGNVSRFDDHGRFKEVSRPSVTTD-----ECGFTNFRRRSNCL 580
68 -12.500[A] KOG4213 RNA-binding protein La  ali follow..  11  81.....EISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLH-KAFKGSIFVVFDSIESAKKFVETPG-QKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTEN..................... 403
69 -10.700[R] KOG2891 Surface glycoprotein  ali follow..  10  147....................................TIHISHLPMR-SENIFKRIFEKFGRVRMVDIPICDPYRKSM--GYVQFEEYSSFVRAMDEFRGNKLVRKNICVSFDKQKHLSDSNIQRRERIRKKFIAKAKAEDEEREKLKKQQEEELDRERQKQEELKKAEAEKQREREERRKEKHMKKIQERGQVEISQKIRIEERKLMIAQRKLESIRTLEKLFERIQLKQRDKNRRVKQDDDKDIQRGRLVEKYKAATEKLVCDQRKIVQEIKSNTPLLGLLKSKSKKSAVPVDASSEDEAAASKRHKMGNGVTESAPPGDVNSALNPLN..................... 479
70 -10.500[A] KOG2217 U4/U6.U5 snRNP associated protein  ali follow..  11  14................................................................................................................KKNRHRSRSSERPRRVTEDEDVTLDLTDDSSSRHRHHKHKKHKEHRHKHHKQKERERANEVISLEESDSDSSDCVEVPVQAQVQAQAKLRDARESSNRDKERDSGRDRELLRERERERDRERERDRDREKEREREREKERLREREEREREREKERIREREKERLRERERERERERVRELTAPPPPQISKHAEYESRREREIERERDARKRSGRERERERN................... 233
71 -10.100[K] COG5175 Transcriptional repressor  ali follow..  13  94.EELKMERAKLARKEKERKHREKERKENEYTNRQKNLVYVVGINPPVPYEEVEKYFGQYGKINKIVVNRKTPHSNNTT-VYITFGSKDDAARCIAQVDGTYMDGRLIKAAYGTTK............................................................................................................................................................................................................................................ 233
72 -10.000[O] KOG0111 Cyclophilin-type peptidyl-prolyl cis-trans isomerase  ali follow..  30  1..............................MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMR........................................................................................................................................................................................................................................... 86
73 -9.900[A] KOG4008 rRNA processing protein RRP7  ali follow..  10  39............................KKDPSKENSIIVSNIPAFVGEGVVLAIIDQFASFEVEESFVDNSLSQGQLTMSITFDKPEAVIQTLALCQ............................................................................................................................................................................................................................................................. 114
74 -9.770[K] KOG4501 Transcription coactivator complex, P100 component  ali follow..  8  459.................................................TAVLEVLPDLGS------------------GFIRLIRYDNSEQVIAAILDDNLPPDLAQMDRQEVYIPPDPQDKQQRQTGLRHFNVHDGDRYDVLTRDQPECIIKQGKGLPGAPRNAEQLLDDKRDLKQLKERQKYAMVEETTLERGEYDDEYDDSYEAQNEGQAPPVSLLRGRLQEAASSSAYNAQDELENDDEESSGGHSDPEPSMRTNRDFCENPEVIRARYEQRQLSKYGQKSGGHGASPSVVGAPKGQGQSQQTQRSRGQKEAHKSTRANHNRKAGAA-----KRSKGMMG...... 735
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;