Scheduled maintenance will begin on May 30th, 2025. Server will be temporarily unavailable — learn more.
current user: public
If you have questions about the server, please let us know.

Query: [R] KOG0255 Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500    .  510    .  520    .  530    .  540    .
# Score Template Links and tools%idFirst MVYTSTYRHTIVVDLLEYLGIVSNLETLQSAREDETRKPENTDKKECKPDYDIECGPNRSCSESSTDSDSSGSQIEKNDPFRVDWNGPSDPENPQNWPLLKKSLVVFQIMLLTCVTYMGSSIYTPGQEYIQEEFHVGHVVATLNLSLYVLGYGLGPIIFSPLSETARYGRLNLYMVTLFFFMIFQVGCATVHNIGGLIVMRFISGILCSPSLATGGGTVADIISPEMVPLVLGMWSAGAVAAPVLAPLLGAAMVDAKNWRFIFWLLMWLSAATFILLAFFFPETQHHNILYRRALKLRKETGDDRYYTEQDKLDREVDARTFLINTLYRPLKMIIKEPAILAFDLYIAVAYGCFYLFFEAFPIVFVGIYHFSLVEVGLAYMGFCVGCVLAYGLFGILNMRIIVPRFRNGTFTPEAFLIVAMCVCWCLPLSLFLFGWTARVHWILPVISEVFFVLAVFNIFQATFAYLATCYPKYVASVFAGNGFCRASFACAFPLFGRAMYDNLATKNYPVAWGSSLVGFLTLGLAIIPFILYKYGPSLRTRSSYTEELast
1 -141.000[R] KOG0255 Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily)  ali  100  1MVYTSTYRHTIVVDLLEYLGIVSNLETLQSAREDETRKPENTDKKECKPDYDIECGPNRSCSESSTDSDSSGSQIEKNDPFRVDWNGPSDPENPQNWPLLKKSLVVFQIMLLTCVTYMGSSIYTPGQEYIQEEFHVGHVVATLNLSLYVLGYGLGPIIFSPLSETARYGRLNLYMVTLFFFMIFQVGCATVHNIGGLIVMRFISGILCSPSLATGGGTVADIISPEMVPLVLGMWSAGAVAAPVLAPLLGAAMVDAKNWRFIFWLLMWLSAATFILLAFFFPETQHHNILYRRALKLRKETGDDRYYTEQDKLDREVDARTFLINTLYRPLKMIIKEPAILAFDLYIAVAYGCFYLFFEAFPIVFVGIYHFSLVEVGLAYMGFCVGCVLAYGLFGILNMRIIVPRFRNGTFTPEAFLIVAMCVCWCLPLSLFLFGWTARVHWILPVISEVFFVLAVFNIFQATFAYLATCYPKYVASVFAGNGFCRASFACAFPLFGRAMYDNLATKNYPVAWGSSLVGFLTLGLAIIPFILYKYGPSLRTRSSYTEE 548
2 -31.400[U] KOG3764 Vesicular amine transporter  ali follow..  14  95........................................................................................................DLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLTN--RIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQP-----------------------------------ESQKGTPLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKM--------------RWLCALLGMIIVGVSILCIPFAKNIYGL--IAPNFGVGFAIGMVDSSMMPIMGYRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGFP-----WLMTIIGIIDILFAPLCFFLRSPPAKEEKMAILMDH 486
3 -30.900[G] COG2814 Arabinose efflux permease  ali follow..  13  21.................................................................................................AQVASWSGVFAMSVCAFALIASEFLPVSLLTPMARDLQVTEGMTGQGIAISGAFAVLTSLFISALAG--SLNRKTLLLGLTLAMGVSGAIVALAPNYAIYMLGRALIGVVVGGFWSMSAATAIRMVPKRDVPRALAIVNGGNALATVVAAPMGAYLSTVIGWRGAFLCLVPVSLIALAWQWKTLPSMPAAARAPGIGQ--------------------------------VFKVFTLFKHPGVVVGMLASSLLFMGQFGLFTYVRPFLETVTNVHGATISLFLLVLGAAGFIGTVLIGRVLQRS-----------FYQTMIVIPVLMALTALALIAFG-----SVAIVLVLLALWGLTGTSAPVGWWAWIAKVFPKDAEAGGGLFVAVVQMSIALGSTVGGILFDHSGYR--TTFVASAVLLAICAVLT...................... 398
4 -28.000[G] COG2271 Sugar phosphate permease  ali follow..  12  24..................................................................................................RRLRWQIFLGIFFGYAAYYLVRKNFALAMPYL-VEQGFSRGDLGFALSGISIAYGFSKFIMGSVSD--RSNPRVFLPAGLILAAAVMLFMGFVSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQI------------FMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGN----------RGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGS--VAASAI---VGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQE 448
5 -27.100[G] KOG4686 Predicted sugar transporter  ali follow..  8  2....................................................AREDEERIVDNEEVSRPTEEDQVVSRAGRRDNELSLPSGGCCMPSSTSHRFMALVFMCLLGFGSYFCYDAPGALQNYFKKDLNLTSAQFTLIYSIYSWPNVVLCFVGGFLID--RLFGIRLGTIIYMMILLIFACGGILDAFWMMILGRFIFGIGAESLAVAQNSYAVLWFKGKELNMVFGLQLSVARFGSTVNFWVMQPIYEYVSNFYKGHTALGVVLLLATLTCVMSMTCALILGWMDKRAERILQRNNNP------------------AGQIPKLTDVFSFKPPFWMVSIICVAYYVAIFPFIALGQNFFVDRFGLSPAEANTVDSLVYLIAAVSSPVFGFIIDKLGR------------NVTWVFTATLTTIGAHALLTFTQLTPYVGMIIMGLSYSMLAASLWPLVALII----EYQLGTAYGFCQSIQNLGLAVITIVAGIIVDHSGGEHMWLQLFFMGWLTIALISTGVIWAY-KNRGNLNMTPQ.... 463
6 -25.600[R] KOG0253 Synaptic vesicle transporter SV2 (major facilitator superfamily)  ali follow..  11  23.....................................................................................................QIYVLAYAGMGWVAEAMEMMLLSFVGPAVQSLWNLSARQESLITSVVFAGMLIGAYSWGIVSD--KHGRRKGFIITAVVTFVAGFLSAFSPNYMWLIILRCLVGL-GLGGGPVLASWYLEFIPAPSRGTWMVVFSAFWTVGTIFEASLAWLVMPRLGWRWLLAFSSV--SSLLLLFYRWTSES-ALAILEKIARMNKTQLPPGVLSSELETELEENKNIPTENTHLLKASLLALLSPTLMKRTLLLWVVFFGNAFAYYGVVLLTTELNN-LRNSNDVNYRDVFIASFAGLLISAAMVDRLGRK---------------ASMASMLFTCCIFLLPLLSHQSPFITTVLLFGGRICISAAFTVVYIYAPEIYPTAVTTGVGVGSSVGRIGGILCPLVAVGLVHGCHQTIAVLLFEVILVSGICVCLFPFETSGRDLTDSISASKEPPSA 498
7 -23.700[P] KOG0252 Inorganic phosphate transporter  ali follow..  10  18..................................................................................................QMYHFTAIVIAGMGFFTDAYDLFSISLVTKLLGRIYTLPPNVAAAVNGVAFCGTLAGQLFFGWLGD--KLGRKKVYGITLMLMVLCSLGSGLSFGMATLCFFRFWLGFGIGGDYPLSATIMSEYANKKTRGAFIAAVFAMQGFGILAGGIVSLIVSSTFDWRIVLMFGAI--ALLTYYWRMKMPETARYTALVARNTKQAASDMSKVLQVDLIAEEEAQSNSNSSNPNFTFGLFTREFARRHGLHLLGTTTTWFLLDIAYYSSAAETMNAIHEVFTVSKAQTLIALCGTVPGYWFTVAFIDIL--------------RFFIQLMGFIFMTIFMFALAIPYDHWRHRENRIGFLIMYSLTMFFANFFVVPAEIFPALRSTCHGISAASGKAGAIVGAFGFLYAAQSSDSEKTGIGVRNSLLMLACVNFLGIVFTLL--GKSLEEISR.... 517
8 -22.600[R] KOG2615 Permease of the major facilitator superfamily  ali follow..  13  13.........................................................................................................LFTVWIIVLCTALPISSLFPFLYFMIDDFNIAKKEEDIGFCSFMLGRAFTSVAWGLVAD--RYGRKPVILIGTASVVVFNTLFGLSLNFWMAIITRFCLGSFNGL-LGPIKAYAMEIFRDEYQGLALSAVSTAWGIGLIIGPAIGGFLAQPAKFFLPCLAISVFAFLVTIVSSRIPETLHNHKFNDDESYDALKDLSDDPESNKVAERNG--------------KSSLLNNWPLISSI-----IVYCVFSLHDMAYTEIFSLWANSPRKYGGLGYSTADVGSVLAFFGLLIFQLSLYSYAERLLGPIIVTRISGSLAMVVLSCYPLIAKLSGLALTVTVTSASVAKSVLGTSAITGLFILQNKAVRQDQRGAANGIAMTAMSLFKAIGPAAAGIIF-SWSEKRQGAAFLPGNVNPNSCSCPCPCPSL................ 440
9 -21.800[R] KOG2563 Permease of the major facilitator superfamily  ali follow..  9  2...........................................................GADDGAISADKVDIRLQPLNKNGAQDETDEEAADQIQLRVYKRWIVLLAVALLNNTNTMSWIGYAPSGNYVNSFYGESS--AAWLSMVYMMCTIPVGMFAMWAGR--EWGLRTAVLIAGWANGIGAVIRVISLRFPICMTGQGIAAIAYPFIMFLPTKVAGSWFPDTQRAIATSIGVMSNPLGVLMANLISPAIVKSPEHVIWLNIFTCVPSLIAMLIATFGVNRSEPKIPPTFSASKPQMD-------------------------FVSGMKSCFSSKQYIILLIVMGGGIGMFNCLYTVMLELLCP-SGYSNFFSGVCAALMIVGGVFGAAASSIFVDRTKLYE----------ETLKIALGAAVIFGLIFLQLTLHQGYSVILGVTCLLFGVLGLATYPIGLELASETFPVSEATSTGLIVLSGQIQSVIYVFIMKNFARPLQPDRMHIQVCQIMIFSLLATLLVLTLVVLFKPVYKRLEAERGNR 476
10 -21.700[R] KOG2816 Predicted transporter ADD1 (major facilitator superfamily)  ali follow..  10  4....................................................................................................FRLGELRHLLVTVFLSGLAEYLIRPVMTDVTVAAVCSGLDDSCSLAVYLTGVGMGTMVMMPLSD--RYGIKAMLTLPMCLSVLPPAILGYRRDTNFFYAFYVIKTL----------FDMAKNVHGTKRISMFGILAGVSSISGVCASLSARFLSIAST----FQVAAISLFIGLVYMRVFLKERLQD-----------------------ADDDDEADSGGCRSHQEVHNGGDLKMLTEPILRDAPTKTHVFNSKYSSWKDMYFLKARFGFNKNDFAELFLLVTIIGSISQLFILPTLSSTIGERK------------VLSTGLLMEFFNATCLSVAWSPWVPYAMTMLVPGAMFVMPSVCGIASRQVGSSEQ--GKVQGCISGVRAFAQVVAPFVYSPLTALFLSENAPFYFPGFSILCIAISLMIGFLQSLLIKDHPSLPLV.... 403
11 -21.500[P] COG2807 Cyanate permease  ali follow..  12  8.................................................................................................SGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAYSLTTAQTGLLTTLPLLAFALISPLAAPVAR--RFGMERSLFAALLLICAGIAIRSLPSPY-LLFGGTAVIGGGIALGNVLLPGLIKRDF-PHSVARLTGAYSLTMGAAAALGSAMVVPLALNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRAL---------------------------------HTRGIWRSPLAWQVTLFLGINSLVYYVIIGWLPAILIS-HGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKD------------QRGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASS--AHQAAALSGMAQSVGYLLAACGPPLMGKIHDANG------NWSVPLMGVAILSLL...................... 378
12 -21.200[P] COG2223 Nitrate/nitrite transporter  ali follow..  10  2....................................................................SHLSAPERATGAVITEWR-PEDPAFWQQRGHRVASRNLWISVPCLLLAFCVWMLFSAVAVNLPKVFNFTTDQLFMLTALPSVSGALLRVPYSFMVP--LFGGRRWTAFSTGILIVPCVWLGFAVQFSTFIIISLLCGFAGAN-FASSMANISFFFPKQKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAAFGSHGVEQPDGSQLYLANAAWIWVPFLAIFTLAAWFGMNELATS-------------------KASLKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAGFAMLSKTQ--FPDVQILHYAFFGPFIGALARSAGGAISDRLGGTRV--------TLINFVLMAIFSGLLFLTLPTGGVGGSFIAFYGVFLALFLTAGLGSGSTFQMISVIFRTDTAAALGFISAIGAIGGFFIPKAFGSSLALTG----SPVGAMKVFLIFYIACVVITWAVY-----GRHSKN.... 463
13 -21.000[R] KOG2325 Predicted transporter/transmembrane protein  ali follow..  8  28.................................................................................................DRLTNWRLIITAAVVSCLNAVENSVLGIGEWPYMREIDPNATAQFFGLSASKCGHAVFALIFSIWSY--KTSSKIPLIASRLIAIAACMIYLTIEYVKTLMAVYTLLGI-ANSGGTVLRGYVTLCSSNEDRPRAFAALGLSFIFSIIVGPTIQLIFSWFHLYSAPIWISFILTILTVFVILILIEDISRE----KKTKLRPSESQSSFSMERWRSLYEKLKKSNL--------------DWKLIVVCFFVRMAVSFSHSTLSTISILYMVMFGWDGATTVRVGITMVIFGVMSSTILLLYIFCHFGKILPQHKVFLFFTIAFGAVYIITYPFEFT-YSWCSTALMLYLSVTILVAGMSIPIMSTALDTVYSRILNIDQSVAHGAMAVIDDILYMITPIFTTTMFTLYGIG--------IVKSMAFGIIALTVLVSGQ.............. 484
14 -20.900[G] KOG0569 Permease of the major facilitator superfamily  ali follow..  9  3.................................................................................................SLSIHILSIALCLSSGFQQGYIASVLNQPYAQIEQFINSSHLLWSLLNVCFPIATIFGQFLAGWMCS--QFGRKHTALIASFLYIPGALLCAAAPAFELLFVGRIIWSLANGVNTVNATVWIVECAPPQIRGRMAAMQEFFMALGSLLTQAVGVPFSTDELWPYNFLPNCAVV-VVSMVMFSWVAESPQFIMEKYNDVDVESEIRICEQSIGKNKEKKKTAGGIESEHSGMEIMFMPWRAKDQTSRLIRYCAWVGVMVKIAYVFTFILYTLSHFTYSQATWLSFATGLLRLPFTLVPVFLVDRL--------------RRPLIIVSMLVSFVSILVMIIAININ-YATFIGLTVLLLVNTCGIGSVRFYAAELVPRNLLSSVSTLTMFEALTKIGVEFAFYPTANVIGAQ--------SLLLFLIPTGVFTVMCYLMCRMTVNE....... 477
15 -20.400[R] KOG0254 Predicted transporter (major facilitator superfamily)  ali follow..  14  27.................................................................................................MMSCADLNVLVATLITFCHGIALGWLSPMLPKLLSPFYIDVNEASWLGAVISIGGISGNFSFSYLMN--RFGRKVSIY----------ALAVPHTSIEWLYVARVFAGLTGGGMFVVLPIFIGEIADNSIRGRLCSFFTLTMNTGIMVGFVVSSHI----AYHVIPCAVVGLP-VLYVLLATRYPEPPQQLIRWKREEEAEKEMRLAIQQQNNDTDDNGLSMSDFLTKRSLKALATGL---VLMVANIFTGTFAFNNYM-----SNIFDAV---TQLDPNTNTIIIGAVQILGTLASIYLVDRY--------------RKILLIVSCAGSGIGTSAFG-SAFSAWL-PVTLMAFIIFIANVGVISVMVVLVEILPQKIRAATSFCLGCLSFFAFASLKTFPLMMFHLGLAATMWFCAAVSVICLFYVVVCLE------GRSMYD....... 472
16 -19.900[G] KOG2532 Permease of the major facilitator superfamily  ali follow..  12  2......................................................................................................QMNTLTLNFTVICMDDIVEDFHMFHNSTETHWFERSTEKSLLFSGVAIGGLIGLVPSVPQIS--SIGLRNTQTISGFISGLGSFLFPLAVSVGTSFLCRVLQGIGAAVLFTAVGVVPGVWAPKSEANTFMSILACAFQLSNVICPVSGLLCESAVGWRSIYYISGAITFVLYTVFWFTYTDDLHRNVSQKELRKISTGKVEKIKEP---------------------PYFAVSTDPTVIISWISLFGGNMGFYVLCIYGPTYLREVLKFDVKETGFLTALPFILSAIAKFSAGRISDKLTGLSERA------RFVFFASIFQIGLVAGLVVMAFTTN-----RVIAQIAFNFAIVSSGLNIMGVVADLPKNLIFVNLPICQFAGSFREILYKIETLKVRCLQHVH---TLTVMSFTAYASQFLSPT.................... 399
17 -19.100[G] KOG2533 Permease of the major facilitator superfamily  ali follow..  10  2.....................ASEWPETSRASSVEENPKLNIPEIVESVSDSKPSLKNQFSTTVIDSSDLNVFNDGAETTVKEQEFTSSELRRLQKLRLKMDLRIIPCLWILYFLSCCLFTVSLSFTMNTAQGHSLIQTLSALGLALFYVGYIIFEV---PSN-MAFIEPRIWVSRIQLTIGVVGACHAVLGNAQSYVALRFFLGVAESGLWPGLAYYMSRWYRGKHLGKRIGWYYTAAQIAAAAVSLVSAGFQKLYGYQWMFLIWGVVAIAQALSIPWWLPAVASKEPLPKWMKTLSPQRIGFLTPADKSLHSRYIAEMNVGKRWQWSDLLKSCLDLRVWPFILMYFGIVGVGNGIFNYCTLIIEEIPSFSGIDISLLNAPIWLADALGIVTVMPLYDRF------------HKKFSFFTGSCLIIIAGLAVANYAPRAW--SRYGGLLMIGFGLGPTVPICMAWCSASMATYGDVGVASSLALVTGLGNLGSVVTTYALYSGWPGDPTFRKSNDVIALIGVSIIACGIEFLLDKTGFGQFNASFNN 542
18 -15.400[G] COG0738 Fucose permease  ali follow..  12  17.................................................................................................SQKNYGFALTSLTLLFFMSGFITCLNDILIPHLKNVFQLNYTQSMLIQFCFFGAYFIVSLPAGQL--VKRISYKCGIVVGLIVAAILFIPAASYRVYALFLGALFVLASGVTILQVAANPYVTILGKPETAASRLTLTQAFNSLGTTVAPVFGAVLILSAATDATVNAEADAVRFPYLLLALAF---------------TVLAIIFAILKPPDVQEDEPALSDKKEGSAWQYRHLVL-----AIGIFVYVGVSVGSFLVNFLSDPTVAGLSETDAAHHVAYFWGGAMVGRFIGSAAMRYID--------------DGKALAFNAFVAIILLFITVA------TTGHIAMWSVLAIGLFNSIMFPTIFSLALHGLGSHTSQG-SGILCLAIVGGAIVPLIQGALADAIGIH---------LAFLMPIICYAYIAFYGLIGSK.......... 411
19 -15.400[S] KOG3097 Predicted membrane protein  ali follow..  9  2................................................................TGFTNAGFENDEPVKPKAGFEPDTASLREKVVLNPGEKWRILKNISIISIAFMVQFTAFQ-GTANLQSSINAKDGLGTVSLSAIYAALVVSCIFLPTL--IRKLTVKWTLVCSMLCYAPY-IAFQLFPRFYTLVPAGILVGMGAAPMWASKATYLTQV-VDAIIVRFFGFFFLAWQSAELWGNLISSLVLSSGAHGGGSSSNTTVSEEDLISMIYLSCIVAAVCIIAFFLDPLKRYGEKRKGSNSAAELSGLQLLSATFRQMKKPNLQLLI--PITVFIGMEQAFIGADFTQAYVA---------ALGVNKIGFVMICFGVVNALCSILFGSVMKYI--------------RTPIIVLGAVVHFTLITVE--PNPDNPIIFYAMSGLWGVGDAVWQTQINGLYGLLFRRNKEAAFSNYRLWESAGFVIAYAYATTLCTQMKL---------ILLAVLTLGCIGYVIVEILYRKKQRKLKK.... 487
20 -14.300[P] KOG3574 Acetyl-CoA transporter  ali follow..  13  2................................SPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQSFRAELSSILLLLFLYVLQGIPLGLAG-SIPLILQSKNVSYTDQAF-FSFVFWPFSL-KLLWAPLVDVKNFGRRKSWLVPTQYILGLFMIYLSTPDVIALTVAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENE------------VSVVKEETQGITDTYKLLFAIIKMPAVLTFCLLI-LTAKIGFSAADAVTGLKLVEEGVPKEHLALL-LQIILPLIISKYTA--------------GPQPLNTFYKAMPYRLLLGLEYALLVWWTPKYYYIVVLLSYALHQVTVYSMYVSIMAFNAKSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVK......................................... 477
21 -13.700[R] KOG3762 Predicted transporter  ali follow..  8  2.........................................................................................ENHVGERTVNIFGKVFAFICRLFYLSFFASFGSLFPLLAVYFKQLGMTAAQAGFLIGSRPIVEFLSGPFWSQFAS-----QKLLLLFSLGSLVLFTLGIGLVQPVTPLLILICLCEFFSAPALPLADAATLHSVRDNPAEFGIRLMAS---VGWGFAMFIMGIALDYSDYTLCFVMCVIFMLAAMGLASKFFDDDVPAPGEVHGLVMDTREAEVSHVVAEKARARITQSEGGGGSENSLLLAMKALASMHILLF-FVSVVVMGGGAGLVFSFLYWHLQDIGGSPVLFGILSVVNHASEIITYFYVFKLINKY--------------HVRVMYLCLAVNFFRFMALSILDNPWMVLPL--QILQGACLATVWSCASSYISLVAPPHAKQHAQYQVGYHGIGKGLGSIIGGSVISIIG--------TRTTFVIYGLICLATCAGSFGLNKLFKYEGIKYGA 571
22 -13.500[GEPR] COG0477 Permeases of the major facilitator superfamily  ali follow..  11  32................................................................................................................AAAVLVFNTQFFHSDDPLSNDL--------LSLSTLALAF-IGSALFGHFGD--KIGRKKTLVASLVLMGGSTVVIGLLPNYAQLCVCRVGQGIGLGGEWGGAALVATENAPEGKRAWYGTFPQLGAPIGLFVANGTFFLVSYLLAWRIPFVSSILLVAVGLYV-------------------RLTLHESHVFVEAEQKGKKLNAPVSVVFTKH--KPMVIGTFIMVATYSLFYIMTAFAQAYSRTAP-EAGYALGLGIPANTFTGLLLISAIVFGIFISISGFYADKI--------------RRKWLIWVTIAIGVLGLMPLFLENGTPVSVFAFLVIGMAIMGMTFGPMAALLPELFPRYSGASLAYN-LASIIGATIAAMISLKINASFG----VMGVGIYLAINALMTFLALLASKETKNVDLTE....... 437
23 -13.300[Q] KOG3626 Organic anion transporter  ali follow..  11  6.......................................................................................................IFLGLFSFVFFLEAIGGSYINSAVQNIERQFQMSSRTSGFMISASDFGIGAGAILVS-MLASPNFRMPHDTYMSLINLEDDTTPIEEYQPIGRFFFSLLLLGIGRTVPWSLGVPLLDDNIKKKSLPAYFGAISSIRVLGPICGYMIGSFCNKDPTWIGAWWMGFLFIGSIALFPSTMLFFFPQGKEGDGSAVQLRDVHKEKLKKSVDEDRTITMKLKD-----FAKSCKKVLSTKIYMGSVLGRVCDVLAFKGYIVFLPKYLENHFGIPQYLVHRGVFGFGLGVATGGYV--------TKKLKLNGRRAAMFVMLMSTLNVCLYSGKIFI---QTGFAYFSPCHAGCREAMQYGSDPVLDFTSCQCAPGGVVSKKFCENTCKTSSVIFFLTVLPGSFVAGLGVRSLSLGLQGMAVSLFG--TLPSPIL---WGLVI......... 661
24 -13.200[S] KOG3098 Uncharacterized conserved protein  ali follow..  8  71.................................................................................................IILFNFSKFPKFYAVTNVILGQKMPKSFVLESVIHSIHIGKYAGYYGQAVMYIIYMIGCLFSPSI--LNEIGAKYILICSAICFASF-PLGFFFVNSYYYYFSQMLLGFGYALYYQGHGGYLTSHSTRKTIESNINIAWCVGCICLLLSSGILATVTHMTL------ERRFSDLEIKLLFGVFLGASVLGIVNFISCPGKDVTNCIQETKKKGTFMEGFKQTCSALTSK-----SMLQLFPLFTVLGTSSSFWLSIF-----TTAMNFTAANSNLTYLAAIYPLSVGVGEIGTALFITQMSRRFKD------------LQPTMLIGAIFSILGFGLVPLLFGHSYLVISVIGVIVGIGDCCLNSCRSVICALAMPDRRAQAFSISKLYQALGSCVLFFASPII--------------YVYTIGVSIHLIIANVFFNITARRTQTMEK.... 516
25 -12.300[E] COG3104 Dipeptide/tripeptide permease  ali follow..  9  2......................................................................TVGASQQTSTIALHNDTGMLMSNLNIFKQPNAFYLIFSIEFWERFGFYG--MQAILTVYMVKIMGMDESASFVLFGAFSALVYGFVAIGGWIGD-KVIGTKRAITLGAIVMMVGYVLLGLSTADHPLVGPTLI--YIAMGFITVGNGLFAKIYPENDLDGAFTMYYMAINLGSFFSMIITPLVAIKMGYGMAFGVSAVGLAITVVNFLFMPVNKMYLVLVAVGSIIASLVCSYLLQNLTLAHGILVVAGLFILGCYFKEAFSMSGIERAKMLVAFILMLQGVVFFVLYFQMPTSLHHIFGFDVAPEQFQALNPFWIMIASPILAATYGKLGDKLAM----------PFKFAFGMALCALSFLVLSWGTSSNWLIASY--AFQSIGELLVSGLGLAMVAQLVPQRMMGFAMGMWFLTSASAAVIAGWVASLTSTPANVSGATE--GEVFAQIGYVTAGIAIVTFMIAPKLTRICRGESE 507
26 -11.500[H] KOG3810 Micronutrient transporters (folate transporter family)  ali follow..  11  28..............................................................................................ECWF-----LPTALLCAYGFFASLSEPFLTPYLLGPDKNLTEREVFNEI-YPVWTYSYLVLLFPVFLATDYLRY--KPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVV-DLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFS-VISLTCVSVAFAVAWFLPMPQKSLFFHHIGWEDIESKIPLNMEEPPVEEPEPKPDRLLVLKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAI---------GGVEA--------------------------VSTLLGAVAVFAVGYIKISWS---TWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYV--------VFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFL.. 457
27 -11.100[E] KOG1237 H+/oligopeptide symporter  ali follow..  13  11........................................................................................ALKSADSSTRRSGGRITFPFMIVTLFGLTLATGWLQNLIVYLIEEYNMKSIAAAKILNIFSGFTFMFPAIGAIAAD-SFFGTIPVILVSSFISLVGVVLLALTTLFDSLLGVLYTAGAGGLRFTLATAG--ANQYEKTKQGSFFNWFFFTWYLAASISATAIVYAEENISWSFGFGLCVAANLLGLIVFIS-FTSLLRVIFAAIRKRKAVVSTNEKDYHSESKKTPTKSFRFFNRAALKQNQWRLCSVQQVIRIIPLVLALFLSTPIAMQLGLTVLQGLVMDRRLGPH-IPAGSLQVITLLSTCLFIIVNDRFLYPFYQKLTGKFPTPIQRVGIGHVFNILSMAVTA-DMSVLWLFPPL--VIVGIGEAFHFPGNVALCYQEFPESMRSLIGICFYTSTALIDLIQKTTAWLPDDINHGRVDN-WILVIGGVLNLGYFLVCSWFYKYRNLENADHEQDAN 554
28 -11.100[G] KOG0637 Sucrose transporter and related proteins  ali follow..  10  14.....................................................................................TALETQSSPEDLGQPSPLRKIISVASIAAGVQFGWALQLSLLTPYIQLLGIPHKWSSYMWLC-ISGMIVQPIV-GYHSD-SRFGRRRPFIAAGVALVAVSV-IGFAADMGHFLTGFWFLDVANNTLQGPCRAFLADLAAGDKTRVANACFSFFMAVGNVLGYAAGSYTNLHKMFPFTM--KACDIYCANLKTCFFLSITLLLIVTFSSLWYVKDKQWSPPQGDKEEKTSSLFFFGEIFGAVRHMKRPM-----MLLIVTVINWIAWFPFILYDTDWREVYGGNSDGDERSKKLYDQGVQAGALGLMFNSIL-----------------------LGFVSLGVESIGRKMGGAKRLWGCVNFILAIGLAMTVLVTKSEHHREIAGPLAGPSSGIKAGVFSLFTVLGIPLAITYSIPFALASIFSTNSGAGQGLSLGVLNIAICIPQMI................ 457
29 -9.130[R] COG1268 Uncharacterized conserved protein  ali follow..  19  2.........................................................................................................................................KAKEVSLVALFVALTSVGAQISVSIGPVP---------LTLQVFFVILAGLVLGPKLGFLSILIYDIGALGIPVFAGFSGGIAHILGPT--GYIIAFPIATFIAG-YLTSLMGLLVIYLIGWMWLARFVGFNKAFILGVLPFIVPDIVKAATAVIIAERLQGNT....................................................................................................................................................................................................................................................... 162
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 0   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.