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Query: [I] KOG0301 Phospholipase A2-activating protein (contains WD40 repeats), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MADDGLGDVPMETESMPQYTISHVIEAHKSDTKALAVTQGGCLISGGRDETVKFWAKKGKQYTKTHAFEQPKGITVNSIAYAELADGWRLFVGRRDGTIAVFGPSQAEPYAIFNEHKQNVCCLHINEKATHMLSGSWDSNVIIWPITELNSSSFTTIVCPGHTLSVWALASFPDLPNTYLSASADKTIRMWFGDTTLSVFKGHTDVVRALVVLSSSHFLSAGNDGHIIHWDVASASILRKFATQAHEFIYSMTLSDSHILTTGEDGTLEFWAIDGGKDGNLAIVSEAVIQLPTTNTWDAKVLLNSDIAVAGSDGRIYIMTTDKNRKADDDILDAFDAEVVAKLTAKTERMKQEEHETVTIKVDIDDRPTQLNLKYKKGTDPGLCAQEFLSENNLPIHYLEEITRFIKDRIPEARAFDLKSGKKVIVDGKEYDYALGVNFGKGEPDKQMPFNVNESPQFAAQRFVERHQLPVSVIPSLAGMISQEMDKLSKGAASAQSGYEDPFTGPGRYVPQGSSNSGGHGADPFTGSGRYVPQASNSSGFDTGFSGDPLTGDGGYRASAPENTGSHAVPLSSLPQNKKKPRGPLVPVPDFYIIGLAGKGEKAIAKLKELNEKQDAFQLNPDQINGLEELFVLPTSSNYSSEVTQSAFEMSLQWPVEHLTPVLDFLRIALTHHSLNSYFCDRERGQELVGRLIAILVSDPADVALKVLVCRCIANAFSHPVGRNLFASTELSTLAPLVVRQVLNEKTVLQMSAATALANWSLALLQQSEQCEQLGPKEDLLRAILNGIESVDSFGYLGEDAIIRLLQALVTVMWGDASVIRLAKNRNIAQIAARLKDAVSNDSGKNIARDIVEMTYAVLast
1 -210.000[I] KOG0301 Phospholipase A2-activating protein (contains WD40 repeats)  ali  100  1MADDGLGDVPMETESMPQYTISHVIEAHKSDTKALAVTQGGCLISGGRDETVKFWAKKGKQYTKTHAFEQPKGITVNSIAYAELADGWRLFVGRRDGTIAVFGPSQAEPYAIFNEHKQNVCCLHINEKATHMLSGSWDSNVIIWPITELNSSSFTTIVCPGHTLSVWALASFPDLPNTYLSASADKTIRMWFGDTTLSVFKGHTDVVRALVVLSSSHFLSAGNDGHIIHWDVASASILRKFATQAHEFIYSMTLSDSHILTTGEDGTLEFWAIDGGKDGNLAIVSEAVIQLPTTNTWDAKVLLNSDIAVAGSDGRIYIMTTDKNRKADDDILDAFDAEVVAKLTAKTERMKQEEHETVTIKVDIDDRPTQLNLKYKKGTDPGLCAQEFLSENNLPIHYLEEITRFIKDRIPEARAFDLKSGKKVIVDGKEYDYALGVNFGKGEPDKQMPFNVNESPQFAAQRFVERHQLPVSVIPSLAGMISQEMDKLSKGAASAQSGYEDPFTGPGRYVPQGSSNSGGHGADPFTGSGRYVPQASNSSGFDTGFSGDPLTGDGGYRASAPENTGSHAVPLSSLPQNKKKPRGPLVPVPDFYIIGLAGKGEKAIAKLKELNEKQDAFQLNPDQINGLEELFVLPTSSNYSSEVTQSAFEMSLQWPVEHLTPVLDFLRIALTHHSLNSYFCDRERGQELVGRLIAILVSDPADVALKVLVCRCIANAFSHPVGRNLFASTELSTLAPLVVRQVLNEKTVLQMSAATALANWSLALLQQSEQCEQLGPKEDLLRAILNGIESVDSFGYLGEDAIIRLLQALVTVMWGDASVIRLAKNRNIAQIAARLKDAVSNDSGKNIARDIVEMTYAV 858
2 -68.000[A] KOG0306 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  10  79HLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGLASGSKDTDIIVWDVINES---GLYRLKGHKDAITQALFLR--EKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEEEPDPKKIKGSSPGIQDTLEAEDGGRILACHGTDSVLELFCVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCEY-ALCSFFVPGDRQVVIGTKTGKLQLYDLASGN-------LLETIDAHDGALWSMSLSPDQRFVTGGADKSVKFWDFELVKDENSTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIF--YVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWG---------LDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGH--HQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMEREAEYEESVAKEVPGETQGDSYFTGKKTIETVKAAERIMEAIELYREETAKMKEHKAICKAAGKEVPLPSNPILMAYGSISPSEIFKGIKSSELEESLLVLPFSYVPDILKLFNEFIQLGSDVELICRCLFFLLRIHFGQITSNQMLVPVI----------------EKLRETTISKVSQVRDVIGFNMAGLDYLKRECEAKSEVMFFADATSHL------EEKKRKRKKREKLILTL...................................................................................................... 942
3 -67.000[U] KOG0276 Vesicle coat complex COPI, beta` subunit  ali follow..  11  4.................RLEIKRKLAQRSERVKSVDLHPTEPILASLYSGTLCIWNYQTQV---MAKSFEVTELPVRSAKFVA--RKQWVVAGADDMYIRVYNYNTMDKVKVFEAHSDYIRCVAVHPTLPYVLSSSDDMLIKLWDWEK---GWACTQIFEGHSHYVMQVTFNPKDTNTFASASLDRTIKIWNSPDPNFTLDAHQKGVNCVDYFTGGDLITGSDDHTAKVWDYQTKSCVQTLEGHTHNVAVCFHPELPIIITGSEDGTVRIWHATTYR-------LENTLNYGLERVWAIGYIKSSRVVIGYDEGTIMVKLGREIPVAS---MDNTGKIIWAKHNEIQTANIKSIGADYEVTDGERLPLSVKEL---GTCDLYPQSLKHNPNGRFVVVCGDGEYIIYTASFGSGLEFVWSSEGECAVRESSIRPTFSAEKIFGGTLLAMCSSDFICFYDWAECRLIQR------IDVTVKNLYWADSGDLVAIASDTSFYILKFNRDLVTSHFDSGRPTEEEGVEDAFEVLHENDERVRTGIWVGDCFIYNNSSWKLNYCVGGEVTTMYHLDRPMYLLGYLASQSRV--KEFNVIGYTLLLSLIEYKTLVMRGDLDKASLPTIPKDQHNSVAHFLESRGMIEDALEIATDPDYRFELAIQLGRLEIAQEIAVEVQSESKW--KQLGELAMSSMAEECMKYAMDLSGLLLLYSSLGDA---------------EGVTKLATLAKEQGKNNVAFLCLFMLGKLELLVESNRIPEAALMARSYLPSKVSEIVALWRKDLSKVNSKAAESLA................................................... 790
4 -63.700[S] KOG0308 Conserved WD40 repeat-containing protein  ali follow..  12  1.MSSCVNTSQTGPKKISFIIRDEHEYSNRSAVSALQYDAQNGLFTGGSDTIIRTWSVPHHKDAQYQGSLEQHTDWVNDMILCG--HGKILISASNDTTVKVWNIERDNKIDCIRTHKDYVSCLAYAPIVEKAVSASFDHNIFVYDINA---NFKTVNNLIGCKDSIYSLATTPNL-SLVLGAGTEKCIRLFDTNEKIMKLRGHTDNVRALVVNDDGTALSAGSDATIRLWDIGQQRCIATCIAHEEGVTLQVDSSFTTVYSAGKDKMVVKTPLYDFTK-------SQLLFKEEAPVKKLLLSEKDNLWVGTWKSDIKRWSIRPSAQL--SIGGDEDGPSTSNANHSVSASSSPPVTFKYIRVKDQK-GQQSTPELVIPGAPAIKKHAMLSDKRHVLTRDSDGNVALYDVLAARKIKDYGKRI-----EEVVDENSRQVYIPSWFVVDSKSGMLQITLDELDALSSWLSSKDAGFDDNDRECKMTNVDAADADDVQKATLNFISLPEHTPLIICEGNGRPLYRLLVGDAGKEFEANELAQIAPMWVIDAIERNQLPKFNKMPFYLLPHPSTNPKQPKKDRLSATEMLQVKKVMEH--------VYEKILSTNDVGSIPLNQIHTKMEM-----YCNDQRLEPDMDLRTVKHLY-WKQS------ELL................................................................................................................................................................................................ 676
5 -63.300[BK] KOG1063 RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily  ali follow..  12  32.LVSFGAQNAVAVFCPKTAQILTTLPGHKASVNCTHWLPTSKLLSGDSDGIIILWELSTLNWRHVLQLPLSHKKGVTCITAYMSETDAMFASASSDGVVNVWDVSFPVCLDSICVDTKAIVTLSLNPGRFALALGGLDNKIKLYSGER-TGKFTSVCELKGHTDWIRSLDFSLPLHTMLVSSSQDKVIRIWKLVSVESVLIGHEDWVYSVEWQPPVIILSASMDKTMMIWRPEKKTCVGELSHCALGFGGHWSPNSLSILAHGYGGAFHLWRNVSSSKESENWQMQKVPSGHFAAVTDVTWARTGELLSVSQDQTTRVFSAWKNHELARPQVHGHDINCVAMVQGKGNHRFVSGAEEKVVRVFEAPLSFLKTLAGGEGSFPEDLQADVQVLGANMSALGLSQKPIYLH-----------SSSEPLERNGGGEGLDTFETVPEAAPAELKEPPIEDQLAFHTLWPESHKLYGH--GNELFSLCSDHKGNLVASSCKAQSASMAEVGTWKAVGRLQSHSLTVTHLEFSYDDTLLLSVSRDRHFSVFSIQRTDNGEVSHKLMAKVEAHKRIIWACSWNPFGHQFATSSRDKTVKIWSVENDARIKQILVLPPFGSSVTAVAWTGLDRNEKSGCVAVGMESKIIETEEGTTATAALALRLEPFMCHVSAVNRLAWRPTEKCESNQSL----------RWLTSCGDDNCVRVFNFKF.................................................................................................................................................. 840
6 -63.000[D] KOG0642 Cell-cycle nuclear protein, contains WD-40 repeats  ali follow..  13  441.DIANNKDALRKTWN-----PKFTLRSHFDGIRALAFHPIEPLITASEDHTLKMWNLQKTAPAEPIYTFRAHKGPVLCVVMSS--NGEQCYSGGTDGLIQGWNTTNPNLRGPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFNDIKELGIPASVDLVSSDP-SHMVASFSKGYTSIFNMET-VDTTANSSCQINRVISHPTLSSITAHEDRHIKFYDNNTGKLIHSMVAHLEAVSLAVDPNGLYLMSGSHDCSIRLWNLESKT-------CIQEFTAHEESIHDVAFHPSKCIASAGADALAKVFV.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 780
7 -62.500[T] KOG4378 Nuclear protein COP1  ali follow..  9  12LLAASGGD-TVKLFDVSADSVLSYTPSPGCAVNSVKWNHTNLVASTGEDKKISLWRKNGQSLGTVKDGGDSAEECLSAISFSKKGS-RYICSGGTGQIVKIWDLQRKLCIKKLKGHTSTITGVMYNCKDEHLASVSVGGDLIVHNLASGARATELK-QVVQFVHVLRLLDYSRSSRHLLVTAGDDGTVHLWDTTGKMSWLKQHSAPTAGVCFSPSNEIASVGMDKKLYTYDSGSRRSSSCIAYEAPFSSLAFGDNGYILVAGTSNGRVVFYDIRGKPQ-----VTVLHAFSNSEDVTSLSWQTSKPIVNEKNYTSEMALLGSTVEDSVVDPLPSTTPSASQSAMAPGSRGVSASTVNASSVEQTPNRNHLWPSGPLGRLHALRANDSYNDDMGVFSPIIDVSSVEKWADSEGYNNKDHLVVDNK---------PSSLLFPSSSKGYSFGDNGSKEHPIFDWK-PSSTSKQDDPRAAFSSFGSITPTASSKSEDSALTPPEAWGGDKFSEKFNQLANEKFSDKFSHLHAPSRLAVSSTGASTSGSMFSSSRDFPLSHGQTNFANASLEFPRIRDFSSTFETSSTQT---------DNNLPSSPLFTKGITAPGNIDSLRLSPNFTRRFSTYAERISTTSSFSDGASLSLGGSPKIKKTGSETREEVLNHLLARPETVVAT-EAGAMPLMNGGLKQSQTDQQQVMGSSNFTLQLFQRTLEGT--------------------------DSFQNSIHDDVRNLHIEILRQ-HEMEMSKVLSSILENQAEQMKELKLLRKENQELRQRL..................................................... 787
8 -60.600[R] KOG0645 WD40 repeat protein  ali follow..  17  1.........................SGHTGRLWSVAAHPMLPFATSSQDKSVRIYNSNTYNLVHVID--GFHTRSIRRVAWRP-IERPVLAVASFDSVVSINEKDDWECTAALEGHENEVKCIAWSCNGNYLATCSRDKSVWIWEATE-DDEFDCLAVLQEHTQDVKVVTWHPTE-DLLVSGSYDNSICFWRDDALTCQLQGHTNTVWALAFSPNGNLASADNDGNVFLWIKISSNQTSLPHIHKGAVYTISWMNDATLCSAGGDGKIVVYQREKHDEALWHVAYEQDHAHGVYEINSLEYLRDDRLLSGGDDGECRVWSFK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 322
9 -60.200[A] KOG0319 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  9  123LLATGSADHIVKVWNLTEQQCTHTLKGP-SVVSAILFGKHEKLVVGYIEGQLNLYNIMRGAPKKLVNTWKSHNSHITALLQVP--DSRVVVALSRDQTMSIHETETQETLRVLPLYES-IEGGAIGHNGN-LFTVGEEGVVKEFVIET----AKLVRKKRIASSNLDHLAYDVVS-NRFLAISAEQNLIILDFENARQIVGFHDEIYSCCLLGKDESMAVASNTSEIRLYNTKTLDCQLIRGHTESVLVVSPTWDTSLLASCSKDNSIIFWRLVTSPENDSTLVPVAAATGHANTVTALAISNTGRLASVSTDCTIKLWGLGVSTKLKESTMVAHGKDVNCVDISESDALIATGGMDKLVKLWQVDTHKMQ-AGTLSGHRRGVGDVKFAKNSHKLASCSGDMTIKIWN---------ISEKSCLQTISGHSCAVFRVIFARNDSQLISADSAGIIKIWTIKTADCECSIDAH--TDKIWSLSKNHNESEFVTAGTDGRIVVWKDVTEEKQKAEDNKRREAIEQDQTLTNLLSQKRYSEALVFALTLAKPFCAFKVINALMAEETPEELGSAIRRLDTRQ--------IEILLQFTVKWNTNSRTSSVAQRVLYEIVHIVDPEELVSMPGAYGYIESFLPYTQRHMDRLDRAKQDVSLFDF-VWRQMRSSV............................................................................................................................................................................................ 793
10 -59.500[S] KOG0271 Notchless-like WD40 repeat-containing protein  ali follow..  13  19.LGGSGILVPVDISTNELQICNQLLGSSDDPVPISFFTTEGAIVDSIRKSLEEIDFETTLKLVRCSASIPGHGEPVISAQFSP--DGRGLASGSGDQTMRIWDIELELPLHTCKSHKSWVLCIAWSPDATKIASACKNGEICIWNAKTGEQ---IGKTLKRHKQWITSLAWQPMHCRLLASCGKDGNIFIWDQGTVVRCLSGHTASVTCLRWGGEGLIYSGSQDRTVKMWRADDGVMCRNMTGHAHWITLALNTDYALRTSCFEPSKRCIKPDTVEECQKVAQTRYE----------AALEIAGGELVSGSDDFTLFMWNPKETKQS-INRMTGHMQLVNQVVFSPDTRYIASASFDKSVKLW--CGRTGKYLASLRGHVGPVYQVAWSADSRLLVSGSADSTLKVFE---------LKTKSLYYDLPGHGDEVFTVDWSPEGTKVVSGGKDKVLKLW................................................................................................................................................................................................................................................................................................................................................................................................................ 471
11 -59.200[D] KOG0267 Microtubule severing protein katanin p80 subunit B (contains WD40 repeats)  ali follow..  10  2.......................SLCGHTSPVDSVAFNSEEVVLAGASSGVIKLWDLEES---KMVRAFTGHRSNCSAVEFHP--FGEFLASGSSDTNLRVWDTRKKGCIQTYKGHTRGISTIEFSPDGRWVVSGGLDNVVKVWDLTA----GKLLHEFKCHEGPIRSLDFHPLE-FLLATGSADRTVKFWDTFELIGTTRPEATGVRAIAFHPDGQTLFCGLDDGLKVYSWEPVICRDGVDMGWSTLGDFCINEGKFIGCSYYRNSVGIWVSDISELEPYGAVSEDSPDYETREIKNIYVDSTGGLNVAQNPGSLKATLPLESRTKSGMLLRPAHVRKTLAKFEESKQSAVVQSATRKKSTQNAFLSEQNASKPFDAEDSIIKGITNKFEKALSSEPPTDEANRMFLKPPRIHRSSNSKYN---------DTRRAMSADPATFGKGGMENSGDVE--IPSKTERVLSREKPGDEQKNTEYPSGSRELNPVKIVEGVNVVSGRTRSLVEKFERGEKTTHTEGASTTIEQNNNAVQEDPRKTSRQTGETPVISTRRARSTPARVMPIVLNRDSNVTSDTQPARTSSFPVMPVILNQASNVTYDEPSVALTQESRTSHARILPVTFNQATNITSEEASVTLRRQRRNSAARVRPVLLSQATSHECPVTSVRPLRTSPARVMPTKLNQSVNMTSDTSHIASMHRVSPTQMLATPITENLMLTHNEFLSTLQSRLTKLQIVRHF----ERSDVKGAIGALLTDQSV-ILTEKIEILTLDMFSQLVPVLTSLLGSRTER-NVSLDMLLKLVAVFGTVI---RSTVSAPRIVGV--------DLHANERNLPN-LFCGTAQDSK 940
12 -58.600[R] KOG0286 G-protein beta subunit  ali follow..  13  2...............GEMEQLRQEAEQLKKQIADARKACADVTLA-ELVSGLEVVGRVQM---RTRRTLRGHLAKIYAMHWAT--DSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN--IVTSSGDTTCALWDTGQQKTVFVGHTGDCMSLAVSPDFNFISGACDASAKLWDVREGTCRQTFTGHESDIAICFFPNGEAICTGSDDASCRLFDLRADQELICFSH-----ESIICGITSVAFSLSGRLFAGYDDFNCNVWDSMKSERV--GILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 339
13 -58.400[S] KOG0293 WD40 repeat-containing protein  ali follow..  12  248.DLSLYSDHQCGKHQI-PSQTAQILESHTDEVWFLQFSHNGKLASSSKDQTAIIWEISADGHISLKHTLVGHHKPVIAILWSP--DDRQVLTCGAEEVIRRWDVDSGDCVHMYEKGGISPISCGWYPDGQGIIAGMTDRSICMWDLDG----REKECWKGQRTQKVSDIAMTDDG-KWLVSVCKDSVISLFDREATVERLIEEEDMITSFSLSNDNKILVNLLNQEIRLWNIEGDPKISRYKGHKRSRSCFGGYKQAFIASGSEDSQVYIWHRSTGK-------LIVELPGHAGAVNCVSWSPTNLLASASDDGTIRIWGLDRINQQNQKKKLVQGSSSNGVIHRCNGN............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 589
14 -58.300[A] KOG0285 Pleiotropic regulator 1  ali follow..  14  91ELRKSATEKALVVGPT-LPPRDLNNTGNPGKSTAILPAPGSFSTAALMERMPSRWPRPEWHAPKNYRVLQGHLGWVRSVAFDP--SNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQ----NKVIRSYHGHLHGVYCLALHPTL-DVVLTGGRDSVCRVWDIRTKMQIVLPHDSDVFSVLARPTDPVITGSHDSTIKFWDLRYGKSMATITNHKKTVAMALHPKENDFVSASADNIKKFSLPKGEF-------CHNMLSLQRDIINAVAVNEDGVMVTGGDKGGLWFWDWKSGHNFQRPGSLESEAGIYAACYDQTGSRLVTCEGDKTIKMWKED----------EDATPETHPLNFKPPKEIRR.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 476
15 -58.100[A] KOG0291 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  9  159LLAIGCRDSSTKIVAINYTKRTYNLSGHTDAIVACFFEANSLLNTISRNGQLCLWECSLAPSDADEPRKEQRDVQLTAANYNT--RTKVLVVAFSSGAFYLYELPDVNMIHSLSISDYPISAALFNCTGDWVALASREGQLLVWEWQS----EQYIMKQQGHSSEMTCIAYSSDG-QFIATGGEDSKVKLWNSSFCFVTFSEHTSGVTGIQFSRNKKLVSSSLDGTVRAFDVNRYRNFRTFTSPNPAQFVAVDYSGELVVAGGQDFDIFLWSVKTGK-------LLEIISGHEGPVVSIAFSPVATLVSGSWDKTVKIWNCLESN--SEHETIDAVSDVTNVTFSPSGEEIAVATLSGNITIF--DIKSAGQVTTIEGRNDYFSTIEYSADGECILAAGKSANICIYHVREAILLKKFEITQNHSLDG-LNDFISRKHLSEFGNMALVEEREELERLPGVQRGDMSSRRFQQ--EVRVFSVKFSPTGQAFAAAGTEGLCI--DKGVVFDPFDLSLEVTPKAVHESLKQQNYTKALVMSLKLNEPNLIALADLSPEFAQRLLQQLARQLQSTPHIEFYLQWSCCLLTKHGNQDGVFQHTGLLALHEVLSRKYEMLN--KICDYNKYTLKVLLDRADKLEQKNE........................................................................................................................................................................................................................ 905
16 -57.900[T] KOG0279 G protein beta subunit-like protein  ali follow..  16  2...............AEGLVLKGTMCAHTDMVTAIATPVDNSIVTSSRDKSIILWKLTKEDKSVAQRRMTGHSHFVQDVVLSS--DGQFALSGSWDGELRLWDLATGESTRRFVGHTKDVLSVAFSTDNRQIVSASRDRTIKLWNTLG--ECKYTISEADGHKEWVSCVRFSPNTLPTIVSASWDKTVKVWNNCKLRNTLAGHSGYLNTVAVSPDGSCASGGKDGVILLWDLAEGKKLYSLEAGSIIHSLCFSPNRYWLCAAT-ENSIRIWDLESKSVVEDDGSTGIGNKTKVIYCTSLNWSADGNLFSGYTDGVIRVWGIGR....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 325
17 -57.600[R] KOG1524 WD40 repeat-containing protein CHE-2  ali follow..  9  1...............MKLKLSASRKTRHTEMVCGVGWIGTEAILSAADDHVFLLTNTATNESQQILN--MPETFFPTSLHIFPGGQNDVFAVSTSDGKINILS-RNGKVENMVDAHNGAALCARWNSDGTGLLSSGEDGFVKMWSRS-----GMLRSVLAQFATAVYCVAWDSTSSNVLYCNADHCYIKSLKMQVAPIKWKAHDGIILCCDWNPTSDIVTGGEDLKFKVWD-GFGQILFNSSVHDYPITSISWNTDGTLFAVGSHNILRLCDKSG--------WSHSLEKMNAGSVMALSWSPDGTLAVGTAAGLVFHAHIIDKRLTEFEIVQTQKTVIEVRDVSSEVSRETLETKERISKIAILYKYSSKNWNTPTMIEYNERTVNIIVQCEKIFLVSDGMTITIFTYEGRKLINLNPPGQV-----MALLDERKIDLANDTLVVRDRADNKVLHFFDPTTGKAQGDGNLKHEHDIVELTVNPLNDRNVAFRDQIGAVHIAMVKTFGVSQRMVKIGSLVEQLVFNDVTNMLCGISEGK---------------PLPNVAFHDRNLLQKSLIQKNIGSVGKFPQLANFAGNTIVIRKSDGCLLPTGILPFYGTLITM-ASQSKWDQAIRLCRSIGNDTMWATFAGLAVLHKNMIVMEIAYAALDDEKVSLINE-----------------------IKDKTDKETRQAMQVVLTGKLADADVLLERSGLSFRSLMLNIQMFK---KRALELGLEIVMGYREKYLKNQKETDPLFLKHMSEVEIDWVHIRELIAAEKAKGNN......................................................... 760
18 -57.600[S] KOG0295 WD40 repeat-containing protein  ali follow..  14  37.LSENDIKPLGGILEKKWTTVLRLQRKVNDLESKLQESQREIHGAPTRDKRQAADWIPRPP---ETQKLTGHRLPITRVIFHP--LWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQ---TYDCLKSLKGHEHTVSSVTFLPTG-DFVLSASRDHTIKQWDTGYCVYTFRGHNDWVRMIRISNDGTFASASLDQTVTVWSFATKSAKLVLRDHEHAVQQPEGNSTHILFSGSRDRSIKAWNINTGD-------VLFTLLAHENWVRGLAFHPKGKLISVADDKTLRVWELSAQRCM--KAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVW............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 401
19 -57.300[S] KOG0316 Conserved WD40 repeat-containing protein  ali follow..  13  1..........MSATEL-PTKEAHILKGHEGAVLAARFNGDGNALTCGKDRTIRLWNPHRG---ILIKTYKSHGREVRDVHVTS--DNAKFCSCGGDRQVYYWDVSTGRVIRKFRGHDGEVNAVKFNDSSSVVVSAGFDRSLRVWDCRS----HSVEPVQIIDTFLDTVMSVVLTK-TEIIGGSVDGTVRTFDMRIGREMSDNLGQPVNCISISNDGNVLAGCLDSTLRLLDRTTGELLQVYKGHISKTDCCLTNSDAHVIGGSEDGLVFFWDLVDAK-------VLSKFRAH-DLVNSIDVDFYLRFFVAGDKRELPPEGRLYVDFFGRQQILTSIDFVIYVSNSPFFFY............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 340
20 -57.300[Z] KOG0318 WD40 repeat stress protein/actin interacting protein  ali follow..  15  38.FLYTN-GNSVIIRNIENPAIADVYTEHSCAVNVAKYSPSGFIASGDASGKIRIWDTVNKEHLTSVGEISGQSKSINSADFRPARP--RIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYDGTSSELVGE--FGSPAHKGGVYALAWKPDS-TQLLTCSGDKTCRLWTPSKPLRVVKGHNKPITVLGLSDDRSIYTGSHDGVVTNWNSGSGTNDRITGTGHGNQINGIAAWGDFVYTCGIDDSLRQFSVEGNSYTDYVVKLNCQPRGIKYEASSIAVNADTSVAVGGDDQKLHIYTLKGGVLEP-KVELDHLGAVTDVSYSPDLKYLVACDAHRKVVLYSVEEYKPAHNKEWGFHSARVNTVAWSPNSLLVASGSLDTTIIIWS--------VANPAKHTIIKNAHPQSQITRLVWLDNNTVISTGQDCNTKVWHVENI........................................................................................................................................................................................................................................................................................................................................................................................................... 608
21 -57.100[A] KOG0265 U5 snRNP-specific protein-like factor and related proteins  ali follow..  15  32ALLESGVRRTSNLQ-----APIMQLEGHEGEIFTAEFHPEGELLSSGFDRQIYIWQVYEDC--ENVMAMSGHSGAVMEAHFTP--DGSHIFTCSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQQLCSGSDDRTIKIWDARKKH-----AAHTLESPFQVTAVCFGDTG-EQVISGGIDNEVKIWDKQAVLHHLRGHSDTITGMSLSPEGDILTNAMDNTLRVWDVRGERCVKVFQGHQHNLRCAWSPGSDKITSGSADRHVYIWDVNTRR-------ILYKLPGHNGSVNAVDFSPKEPILSGSSDKTLYLGEIDE....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 347
22 -57.000[K] KOG0263 Transcription initiation factor TFIID, subunit TAF5 (also component of histone acetyltransferase SAGA)  ali follow..  13  255.QSPKLLKEFRKLHEPNAEDAPSRDYIPLPPHKGVDILSEVEAVK-DWSKRLHLGPRASLP-SVCMYTFHHTNNNMNCAEFSP--DSTMIACGFQESYIRLWSIKDSDGSVRLLSHSGPVYGTTFSPDNKYLLSCSEDASARLWSVDT----KTALVAYKGHTGPVWDVAFGPFG-HYFATASHDQTAQLWSHIYPLRVFAGHLSDVDCVTFHPNSAVLTGSSDKTCRLWDVHRGHSVRVFNGHTQPVAVAIAPDGHTMASADSEGLIHLWDIGTGR-------RIKTMRGHRGNIYSLSFSRESTLVSGGSDCTVRAWDVFKTN--YNNPVSSSLTGSVVTPFSAKTSTFNE----------VNWSTSPDQMVALYTKQTPIFNVSFTRRNLCLAISV........................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 642
23 -57.000[S] KOG0296 Angio-associated migratory cell protein (contains WD40 repeats)  ali follow..  13  34.EDEAEQEQNDTMNNMVMDMSVQGFFEHKDSVFSVSINPVHSCASGGGDDLGYIWDITTGE---QICQLTGHKDSIVAIDWSF--DGTYIATGGMDSQVRLWKSSTGFEFITAFETVDEIVWLSWHPKGLFLAAGCNDGSIWMWSLPS----GKVVQVMYGHTAPVNAGKFIPPGGKRLATVDDSGTLIVWNDHRFDPGNEETAAGWTSFDCNAEGNLFLGGSSGKVKVVNINSSHILASLEAQTESVAIALCTALPICACASVDGTVALYDSASLK--------FRKSLPHEQAVIDCKFLPNTPLLTACADCVIRKWDVRSGQLL--GEYTGHQEPILCMAITPDGKRVVTGSDDTELLVFDCE............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 398
24 -56.300[R] KOG1539 WD repeat protein  ali follow..  10  161.VLVGSQEGPLQLWNINTKKMLYQFKGWGSSVTSCVSSPALDVAIGCADGKIHVHNIKLDE--EIVTFEHASRGAVTALSFSTDGR-PLLASGGSFGVISIWNLNKKRLQSVIDAHDSSIISLNFLANEPVLMSASADNSLKMWIFDTNDGDPRLLRFRSGHSAPPLCIRFYSNG-RHILSAGQDRAFRLFSVIQ-CNVVTCHMDTAEAYVWRLQNFVLGEHILKPCPENPTPIKGVFVSRNHLLLAIACAISACGNFAVVGTAGGWIERFNLQSGISGSYFDMSEKRRYAHDGEVIGVACDSTNTMISAGYHGDLKVWDFKKRELKSQ----DVGCSLVKIVYHRVNGLLATVADDFVIRL---DVVTLKMVREFRGHTDRITDLCFSEDGKWVISSSMDGSLRIWDVILAKQIDGVHVDVP----------ITALSLSPNMDVLATAHSDQNGVWVNQSMFSGLPSVESYASGKDVVNVKLPSVSALTSSEADDDMDRQVLENSEALQASSFSISQKQIPELVT---SLLPKSQWQSLINLDIIKARNKPIEPPKKPEKAPFFLPSIPSLSGDILFKANDSEADGENEENNKKDQNSMKNFDALESPFSKHLKSSWDSKHFLDFTNYMKSLSPSA-------------------------LDMLRMLEIIDEDVEEELIKRPEFILIGQLLDYFINEVSCKNDFEF-MQAVVKLFLKIHGETIRCHPSLQEKAKKLLETQSLVWQKMERCIVTFLSNSQF................................................................................................ 931
25 -56.000[S] KOG0281 Beta-TrCP (transducin repeats containing)/Slimb proteins  ali follow..  16  177.KIIQDIETIESNWRCGRHNL-QRIQCRSENSKGVYCLQDEKIISGLRDNSIKIWDKTSL---ECLKVLTGHTGSVLCLQY----DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGL--MVTCSKDRSIAVWDMASAT-DITLRRVLVGHRAAVNVVDF---DDKYIVSASGDRTIKVWSTCEFVRTLNGHKRGIACLQY-RDRLVVSGSSDNTIRLWDIECGACLRVLEGHEEL-VRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRASTLCLRTLVEHSGRVFRLQF-DEFQIISSSHDDTILIWDFLNVP--PSAQNETRSPSRTYTYISR................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 508
26 -55.400[R] KOG4227 WD40 repeat protein  ali follow..  11  26.DPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGGLVSGGDDRRVLLWHMEQASRVKPIQLKGEHHSNIFCLAFNS--GNTKVFSGGNDEQVILHDVESSETLDVF-AHEDAVYGLSVSPVNNIFASSSDDGRVLIWDIRESPHG--EPFCLANYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRKLRYGGNLSLQSAMSVRFNSNGTLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCTMK-RDQYILSGSDDFNLYMWRIPADPEARVVNGAFMVLKGHRSIVNQVRFNPHTYICSSGVEKIIKIWSPYKQPGC-TGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQSVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSGYTDSESSASLPRSRYQDKRLLALSNESDSEENVCEVELDTDLFPRPRSPSPEDESSSSSSSSSSEDEEELNERRASTWQRNAM-----------RRRQKTTREDKPSAPIKPTNTYIGEDNYDYPQIKVDDLSSSPTSSPERSTSTLEIQPSRASPTSDIESVERKIYKAYKWLRYSYISYSNNKDGETSLVTGEADEGRAGTSHKDNPAPSSSKEACLNIAMAQRNQDLPP----------------ETPRTPSNGPGHEHSSHAWAEVPEGTSQDTGNSGSVEHPFETKKLNGKALSSRAEEPPSPPVPKASGSTLNSGSGNCPRTQSDDSEERSLETICANHN--PHNNGQNLGELE----------VVAYSSPGHSDTDRDNSSLT----GTLLHKDCCGSEMACETPNAGTREDPTDTPATDSSRALKRQRIEL.... 926
27 -55.400[B] KOG0273 Beta-transducin family (WD-40 repeat) protein  ali follow..  17  156.SKPMEIDGDVEIPP----NKATVLRGHESEVFICAWNPVSDLASGSGDSTARIWNLNENSNGGSTQHDVPSNKDVTSLDWNS--DGTLLAMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHT----GEAKQQFPFHSAPALDVDWQNNM--TFASCSTDMCIHVCRCDHPVKTFQGHTNEVNAIKWDPSGMLASCSDDMTLKIWSMKQDACVHDLQAHSKEIATSNPNSSIMLASASFDSTVRLWDVEQGV-------CTHTLMKHQEPVYSVAFSPDGKLASGSFDKYVHIWNTQSGSLVHS----QGTGGIFEVCWNARGDKVGASASDGSVCV................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 519
28 -55.200[A] KOG0268 Sof1-like rRNA processing protein (contains WD40 repeats)  ali follow..  12  81TVLSGACDGEVRIWNLTQRNCIRTIQAHEGFVRGICTRFCGTFFTVGDDKTVKQWKMDGPGYGDEEEPLHTILGKTVYTGIDH--HWKEAVFATCGQQVDIWDEQRTNPICSMTWGFDSISSVKFNPIETLLGSCASDRNIVLYDMRQAT-----PLKKVILDMRTNTICWNPMEAFIFTAANEDYNLYTFDLDTPVMVHMDHVSAVLDVDYSPTGKFVSASFDKSIRIFPVDKSRSREVYHTKRMQHVVKWTSDSKYIMCGSDEMNIRLWKANASEKLGLTSREKAAKDYNQKLKEKFQHYPHIKRIARHRHLPKSIYSQIQEQ--RIMKEARRRKEVNRIKHSKPGSVPLVSEKKKHV.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 440
29 -55.100[A] KOG0299 U3 snoRNP-associated protein (contains WD40 repeats)  ali follow..  14  119......LDYTSKINPDVKIETAQLRGRHMRPLVGVVAYENF-VYSADKSGLIQKWEALQEKDTENRRGENDHVKEITCLAISN--DGRWIVTGGLDHRIVIRDSVTLEPQHCWKHHRDAVMGLAMRRGTNEMFSCSADRSIKVWSLDQ----MSYIETLFGHQDVIFGVDALARE-RCVSVGGRDRTSRLWKGGTSMKATAGYMEGSVDCVAMIDEDFVTGSDNGVIALWSVQRKKPLFTYPLAHGLTSLAAIPYSNLFASGSWDGNIRLWKIAEGLR-SFEPLTIATPLSVYGCINSLSLSLQGKFAACGRETRVGRWKTLRGIPNS---GFVFNIPLTVIPSVTDGDEIDE......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 524
30 -54.700[R] KOG1334 WD40 repeat protein  ali follow..  10  251..ARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTLASSGDDLRVIVWDWVRQK--PVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASNTKRVAKHRGPAHELALEPDSYKFLTSGEDAVVFTIDLRQDRPASVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRHHLVYCDFPTNITCVVYSHDGTLLASYNDEDIYLFNSSLSDGAQYVKRYKGHRVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQF------MEGDRGDIVNCLEPHPYLPLATSGLDQHVRIWTPTAKT---ATELTGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFV----RHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDT...................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 667
31 -54.700[S] KOG2106 Uncharacterized conserved protein, contains HELP and WD40 domains  ali follow..  10  148TVYFIAS--VVVLYNVEEQL-QRHYAGHNDDVKCLAVHPDRITIATGQPPHVRIWDSVTLNTLHVIGI-GFFDRAVTCIAFSKSNGGTNLCADSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGEITSLLLDTRRKLPLIRSDYSRTRKAKVVLCVTFSENGD--TITGDSSGNILVWGKGTSYAVQGAHEGGISPLCMLRDGTVSGGGKDRKLISWSGNYQKLRKTEIPEQFGPITVAEGKGDVILIGTTRNFVLQGTLSGDF--------TPITQGHTDELWGLAIHASKPFLTCGHDKHATLWDAVGHRPV---WDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFV---DTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKY-----TRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVPEGSDGTDINAVCRAHEKKLLSTGDDFGKVH-PCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDT.............................................................................................................................................................................................................................................................................................................................. 709
32 -54.400[JT] KOG0643 Translation initiation factor 3, subunit i (eIF-3i)/TGF-beta receptor-interacting protein (TRIP-1)  ali follow..  10  5.......................LLQGHERSITQIKYNREGDLFTVAKDPIVNVWYSVNGE---RLGTYMGHTGAVWCVDADW--DTKHVLTGSADNSCRLWDCETGKQLALL-KTNSAVRTCGFDFGGNIIMFSTDKQMVSFFDLRDPSDNNEPYMKIPCNDSKITSAVWGPLG-ECIIAGHESGELNQYSSGEVLVNVKEHSRQINDIQLSRDMTFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKLAFEEEFGRVKGHFGPINSVAFHPDGKYSSGGEDGYVRIHYFDPQYFEFE................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 322
33 -54.400[S] KOG0282 mRNA splicing factor  ali follow..  15  261VGVNLRSTMPPEKCYLPK-KQIHVWSGHTKGVSAVRLFPLSLLLSCSMDCKIKLWEVYGER--RCLRTFIGHSKAVRDICFNT--AGTQFLSAAYDRYLKLWDTETGQCISRFTNRKV-PYCVKFNPDEDLFVAGMSDKKIVQWDIRS----GEIVQEYDRHLGAVNTIVFVDEN-RRFVSTSDDKSLRVWEWDIFKYIAEPSMHSMPAVTLSPNGKLACQSMDNQILIFGAQNRFRLNKKKIFKGACQVDFSPDMSYVISGDGNGKLNIWDWKTTK-------LYSRFKAHDKVCIGAVWHPHETVITCGWDGLIKLWD.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 579
34 -54.400[B] KOG0639 Transducin-like enhancer of split protein (contains WD40 repeats)  ali follow..  13  456MQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDNRDNYIRSCKLLP--DGCTLIVGGEASTLSIWDLATPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHN----QTLVRQFQGHTDGASCIDISNDG-TKLWTGGLDNTVRSWDLREGRQLQQDFTSQIFSLGYCPTGELAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGA--------SIFQSKESSSVLSCDISVDDKIVTGSGDKKATVYEV......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 768
35 -54.000[R] KOG0646 WD40 repeat protein  ali follow..  13  5VIASSSIDEGIGSWDLKTGTEQLQFKPCASPAHGLTAVGEKQLSARNTSGSIFYWSWTKPQ----AEVKSYPVEPIKALAANN--EGTYLVGGGISGDIYLWEVATGKLLKKWHGHYRSVTCLVFSGDDSLLVSGSQDGSIRVWSLIRLQGNTLYEHNFNEHTMSVTDIVIDYGGCNVIISSSEDRTCKVWSRGKLLKNI-IFPSVINALALDPGGCFYAGARDSKIYIGAINATQVLGSVSEKGKAICLAYCADGNLLISGSEDGVVCVWDPKSLR-------HVRTLIHAKGSRKGPVNNIQRKTIVANSNKTQVSWKSRGAL-----IPPPLEKYERPVEDTMDGIVTVDPPPFSDVPVYSS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 374
36 -53.300[S] KOG0310 Conserved WD40 repeat-containing protein  ali follow..  10  2...AQPYLPAEKFLSRKQ-ETILLDEDEPAVVSSVRISPKKPHVATTSSVRLTLYDTVVC---EPLNLFSRFKKGVCSIDFRH--DGRLLAIGGDEGKVRIFDVESKVALRVMQASQSTVKSVHFSPRGDTVFSMADDGKIKQYRVADTAVNAVPIIEIQAHEDAIRCGAVSSINDHIVLTGGYDHKVRLWDIRSKEKSLEDCEHPVESVLFLPGEQLIATAAGPIVKIWDTTTGRQLTALQAHYKTVTLRLATNSTCLLSAGIDRRVNAFRTTNYSLINSWS--------MPSPVLDIDVSRDDQMAIGMGNLLALYRRAEIKK--EATASAAIEDKRSLIRTSAPPVKLVEKDRDMQKVDVVAKNADKLKI---PKIDGMLSNFKHAAVIKLLFG--------------------------GKFRSAMDTAVVSYVIVMRGAIHRALAGQERSVQKNILVFLNHNLYKAQYFSTLKEVV......................................................................................................................................................................................................................................................................................................................................................................................... 447
37 -53.200[S] KOG1409 Uncharacterized conserved protein, contains WD40 repeats and FYVE domains  ali follow..  12  4IINQRVEQGESSMGG-AKPALLHRITGHVARINDVILLSKDEVWTASDDRSVRLYLKRDNDQFWP-SIHHFMPVAPTSLYYSE--ETYKLLVGLINGNVYEFDFNSMTESRKWTCHAGPISGLGFALSSELIFSCSRDKSIVWHCSENSN-------KMGSYLLENSCTAMVIDL-PFVFVGDHGGHVTVLRQPNLVSKLSAHTNAITSLTWDGNKKLYSGSSDHLIIMWDIGGGREAYELNGHNGKVTLCAAPAAKRLFSADEHGKLMCWDMNCKRVETPEWKTSDCCQK------NQPFFWNLQMWQRKVVGLRQHHCRTCGSAVCG-SCCDNWTTYPPMGYETKIRICNDCNARM---KDNPQNFNLTPLAIPHEIHTGITAMHLQETLGLLVTSGQNRVIMIWDVRSVCSAPSGSQ...................................................................................................................................................................................................................................................................................................................................................................................................................................................... 415
38 -53.100[A] KOG1272 WD40-repeat-containing subunit of the 18S rRNA processing complex  ali follow..  10  9NLMEKVLPPVEQVLTWTLIQICMQESDVELETKVKKYLRGEGNLETLKDKKLKTQLASRE---KLYGKSAKAAAKIEKWLLPA--EAGYLETEGLEKTWRVKDILSSRNQYDIVLPDFGPYKLDFTASGRHMLAGGRKGHLALLDMMNMS-----LIKEIQVRETVRDVAFLHND-QFFAAAQKKYAYIYGRDGTELHCL-KERGPVARLRFLKNHFLASVNMSGQLHYQDVTHGGMVASIRTGKGRTVMEVNPYNSVVGLGHSGGTVTMWKPTSQAP-------LVQMQCHPGPVSSVAFHPNGHMATSGKERKIKIWDLRKFE----EVQTIHSFHAKTLSFSQKGLLAAGTGSFVQILGDSSGGSSHNYMNHSMVKGYQIEKVMFRPYEDVIGIGHSMGWSSILI----------PGSGEPNFDSWVANPFETSKQRREKEVHSLLDKLPPE................................................................................................................................................................................................................................................................................................................................................................................................................... 445
39 -52.800[S] KOG0772 Uncharacterized conserved protein, contains WD40 repeat  ali follow..  11  5TAPKKNSEKKARVFDLQNAPRTEEPTHVPQSVSVSSKSESGVSSAVSDDEDDFMPDLPPGF-----QMQQSEAGPSSSRAEGP--EDSDDSDFDETEAISIIKLIPAACEAKISHGTQAISALRVEPPGVRFASGGLDYYVKLFDFQKMDMSMRYKELLPAESHVINSLAFSPNG-ETLVVASGEAIIRLLDRAG-LNITKGHTATVNCVEFNPLNKFISCSDDGSLRLWNLDDHKVITKCINKHRKVICTFSPDGKWIAAGCDDGSVQAWKYGSQY----VNVNYLVRKAHNGSITSIAFSPDSKLLSRGFDDTLKMWSLDNPKELLVKTGLENAFKSTDCGFSPRAEVVFTGTSSPN-TLQFFDPMTFDLVYKIDYPGISCHRIQWHPRLNQIIAGLSDGTIHVYYDQTMSQRGVMSCVTKPLREDMVLSPLSLEMFQPRGEEGEEKEVTGWRIKKYLRMQDNKLRPEFRKPADMPI-NGKSANGRVAASGGSLHSYLAKQIGTARNAEFLKDTDVRASILKHAKDAEENP------IDKAYRKTQPKKIFQETAVEPEDQDDEELQPVFKMPRTK........................................................................................................................................................................................................................................................................................ 620
40 -52.600[Z] KOG1523 Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC  ali follow..  11  1.....................MSLHQFLLEPITCHAWNRDRTIALSPNNHEVHIYKKNGSQW-VKAHELKEHNGHITGIDWAP--KSDRIVTCGADRNAYVWSQKDGVPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFEAENDWWVSKHIKKPIRSTVLSLDWHPNN-VLLAAGSCDFKCRVFSAYISEFGGSGTGGWVHGVSFSASGSLAWVSHDSTVSVADASKSVQVSTLKTEFLPLLSVSFVSENSVVAAGHDCCPMLFIYDDRGCLTFEDRNTALETLHQNSITQVSIYEVDKFCTTGIDGAMTIWDFKTLESS................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 363
41 -52.500[ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2  ali follow..  14  2.........KIKLIDVRSFKVAKIFRENTDKINAIDFAPNGELISCSEDDQIVIYDCEKGT---QSRTVNSKKYGVDLIHFTHANNTAIHSSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKTLRLWDLRSPNCQGLM------HLSGRPIAAYDPEG-LIFAAGVNSESIKLYDLRSTFKLNQEKECDWTGLKFSRDGKILISTNGSVIRLVDAFHGTPLQTFTGYPNNIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSV------LNGDHPGPVQCVQFNPKYMLASACTNMAFWLPTSEEG...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 316
42 -51.900[R] KOG0315 G-protein beta subunit-like protein (contains WD40 repeats)  ali follow..  12  8ILATGGYDHTIKVWQAHTGNCIKTMRVETSQVNALDRTPDKTRLAACGYQCIRLYDLESNC-TAPVINFDGVQKNVTRLGFQE--DGNWMFTAGEDHHVRIWDMIAAPPHSRIFDCEAPVNAACLHPNQVEIAMGSQNGSVFLWDVKS----ERHERIVPEVDASIQDVAISPDG-RYLAAANNKGNCYIWSLTSPNRKIPAHSRYILRCKFSPDSRLLTTSGDGTVCIWKTDDFSKWRELCIENYWVDAAFSADSKWLFTASSDGIARLWKLQTKS-------SIRDYTGHTKAITALSFKDEIPKSTNISDVQSSAKPP--------TQRDNPPGTNNLAFFETVGRVAMNPYMGNTTTEL............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 361
43 -51.900[R] KOG2394 WD40 protein DMR-N9  ali follow..  11  149LVFNVSDAIFICDLNSQEKDPVKSIHFSNSNPMCHAFAKDGHLLIGLNSGDVYTVSLRQQLQDNKDGSVNNRQDRCTSISWVPTESTFPAIRDPTQFSVDKAKYSKSNPVARWHICQGSINSIAFSNDGAHLATVGRDGYLRIFDFLT----QKLVCGGKSYYGALLCCSWSMDG-KYILTGGEDDLVQVWSDRKVVAWGEGHNSWVSGVAFDSNWSFGSVGQDTQLLLWDLEMDEIVVPLRRAPGGSPTYSTGSSAHIPMGTLQPAPCKRDVPKLSP-------IIAHRVHTEPLSGLMFTQES-VVTACREGHIKIWTRPSESETQTSSEANPTTALLSTSFTKDNKASLSSKIISGSTFK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 555
44 -51.800[A] KOG0284 Polyadenylation factor I complex, subunit PFS2  ali follow..  11  106.AVPADSTPDVPVDCILTKFIRTAMNKVKCPVYSVCWSPEGKLITGCQTGEFTLWNGTAFN---FETILQAHDSAIRALKWAS--NEQWLLSADQGGYVKYWQPNMNNAHMFSAHKDEAIRGLAFAPTDVKFATASDDGTARVWDFAR----YTEERVLRGHGAEVRCIDWHPTK-GLIATGSRDQPVKIWDSGSCLATLQEHKSSVMAVEFNKNGNLLTGGRDHLVKMYDIRMMKEMRTYRAHKKEVSLAWHPIHEGFVSGGGDGSIVYWMVDGEKEIGL------LEHAHDQAIWSMKWHPLGHLATGSNDNNTKFWARNRPGDTSNTNMIGHLDKEREPRMAPPKPSIETQETYRPDTFIPGMGLDEHLYEQLNRDHNMMTTDSTLLVPDDLTRQNFAPMIGAKRTLIKQPPAKK--------AQRQFERMWNNSKGIGAGSDDFTTMKGGLGREDAEG............................................................................................................................................................................................................................................................................................................................................................................................................ 558
45 -51.700[S] KOG1407 WD40 repeat protein  ali follow..  14  2......EETTIPFKSLH----SREYQGHKKKVHSVAWNSNGTLASGSVDQTARIWNIEPHGHSAKDLELKGHTDSVDQLCWDP-KHSDLVATASGDKSVRLWDARSGKCTQQV-ELSGENINITYKPDGTHVAVGNRDDELTILDVRKFK-----PLHRRKFNYEVNEIAWNMPG-DFFFLTTGLGTVEVLSSLKPLDTLTAHTAGCYCIAIDPKGRFAVGSADSLVSLWDISDMLCLRTFTKLEWPVTISFNYSGEYIASASEDLFIDIANVQTGRTVHQIPCR--------AAMNSVEWNPKYNLAYAGDDKNPKYNTDEGV...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 306
46 -51.600[U] KOG0277 Peroxisomal targeting signal type 2 receptor  ali follow..  16  2..............SAVCGGAARMLRTPGRHGYAAEFSPPGRLACATAQGTLLILDPDEAG--LRLFRSFDWNDGLFDVTWSENNE-HVLITCSGDGSLQLWDTAKAGPLQVYKEHAQEVYSVDWSQTRGLVVSGSWDQTVKLWDPTV----GKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDAAGVRIVIPAHQAEILSCDWCKYNELVTGAVDCSLRGWDLRNRQPVFELLGHTYAIRRVK--HASVLASCSYDFTVRFWNFSKPD------SLLETVEHHTEFTCGLDFSLQSPVADCSWDETIKIYDPACLTIPA.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 323
47 -51.000[Z] KOG0313 Microtubule binding protein YTM1 (contains WD40 repeats)  ali follow..  15  75..ISSEEVVEIEYVEKCTAPQPEQCMFHDDWISSIKGAEEW-ILTGSYDKTSRIWSLEG----KSIMTIVGHTDVVKDVAWVKKSLSCLLLSASMDQTILLWEWNVEKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDETRTPIVTLSGHMEAVSSVLWSDA--EEICSASWDHTIRVWDVGSSLKSTLTGNKVFNCISYSPLCKLASGSTDRHIRLWDPRTKDVSLSLTSHTGWVSVKWSPTHEQLISGSLDNIVKLWDTRSCK------APLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTT..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 418
48 -50.800[R] KOG0288 WD40 repeat protein TipD  ali follow..  14  162WMLQKMQD--AERLNEANDLYEEMLAKLKANGLETLARQQVDIVRRNEDGTDHFVESTIPS--TCANRIHAHEGGCGSIVFEY--NSGTLFTGGQDRAVKMWDTNSGTLIKSLYGSLGNILDMAVTHDNKSVIAATSSNNLFVWDVSS----GRVRHTLTGHTDKVCAVDVSKFSSRHVVSAAYDRTIKLWDKGYCTNTV-LFTSNCNAICLSIDGLVFSGHMDGNLRLWDIQTGKLLSEVAGHSSAVSVSLSRNGNRILTSGRDNVHNVFDTRTLEICGTLRASGNRL---ASNWSRSCISPDDDVAAGSADGSVHVWSLSKGNIV--SILKEQTSPILCCSWSGIGKPLASADKNGYVCTWT.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 515
49 -50.400[U] KOG1332 Vesicle coat complex COPII, subunit SEC13  ali follow..  16  5....................INTVDTSHEDMIHDAQMDYYGTLATCSSDRSVKIFDVRNGGQ-ILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGEKSHEHAGHDSSVNSVCWAPHGLILACGSSDGAISLLTYTG-EGQWEVKKINNAHTIGCNAVSWAPAVIKRFASGGCDNLIKLWKEEEEEQKLEAHSDWVRDVAWAPSIGIASCSQDGRVFIWTCDDASSPKLLHKFNDVVHVSWSITANILAVSGGDNKVTLWKESVDGQ-----VCISDVNKGQGSVASVTEGQQNE........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 321
50 -50.300[YU] KOG2445 Nuclear pore complex component (sc Seh1)  ali follow..  12  1....................MQPFDSGHDDLVHDVVYDFYGRVATCSSDQHIKVFKLDKDTSNELSDSWRAHDSSIVAIDWASPEYGRIIASASYDKTVKLWEEDPDQELCTLNDSKGSLYSVKFAPAGLKLACLGNDGILRLYDALEPSEMKVLSIPPANHLQSDFCLSWCPSRSPEKLAVSALEQAIIYQRGKVAAKLPGHKSLIRSISWAPSIGIATGCKDGRIRIFKITEKLSPLASEESLTNSMFDNSADVDMDAQGRSDSNTEEKAELQSNL---QVELLSEHDDHNGEVWSVSWNLTGTLSSAGDDGKVRLWKATSNEFKCMSVITAQQ.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 349
51 -49.700[S] KOG0321 WD40 repeat-containing protein L2DTL  ali follow..  12  3MDIGKALSDVGGLRDITSANNSLPPTPDSSPAAPSKKHKLYDLESRGKIETPRKRIVFEKKYSRPSECLMMLNQLPFCLGFAN--NESLLAVCTETGALELFDSRSARRIHGWLAHNNAIFSVNFSKDDSLLATSSGDQTSKVFDLSTQQTRLGRRGVDGYHSHSVKQVNFCNDSPYNLVSCSRDGSIIFWDMRTKAHENSGRDCSITSATWLPQSTISSCSANSALKLWDLRTVHTVRPLPAATGVTNVCTSPDGERIYAASRDSIIYEYSSRHLNSGFCK-TYKDPRLRISSFYVKLACSPDGATLACGGTSGVVVFDTTRNCSSSAMLTGGHTKDVTAVDWSSEGQL-ASISDDGSVRVWNSSLHGSAA-NLREKNFSEIFYWGFSEK................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 490
52 -49.500[R] KOG0289 mRNA splicing factor  ali follow..  12  110.HDAACRVIARLTKEVAAREALATLKPQAGLIVPQAVPSSQPVVGAGEPMDLGELVGMTPEIIQKLGLHSASIPGILALDLCP-SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPN----ASCVQVVRAHESAVTGLSLHATG-DYLLSSSDDQYWAFSDTGRVLTKVTTSGCSLTCAQFHPDGLFGTGTMDSQIKIWDLKERTNVANFPGHSGPISIAFSENGYYLATAADDSSVKLWDLRKLKNFK------TLQLDNNFEVKSLIFDQSGTLALGGTDVQIYICKQWT----EILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFY............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 502
53 -49.400[T] COG5170 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  12  1MDDIEDSLDQWKFAQCFGDKGDVEDITEADIISAVEFDHTGDLATGDKGGRVVLFERNHSKKGCEYKFSLEIEEKINKIRWCKRTNRAHFLLSTNDKTIKLWKLYEKNLKVVANAHAYHINSISVNSDAETYISAD-DLRINLWNLSISDHSDIKPENMEELTEVITSAEFHPINCNHLMYSSSKGNIKLLDLRQSKSFFSEIISSISDVKFSQNGRYILSRDYLTLKIWDVNMKAPVKTIPLHDDKFECTFSGDDKHVLSGSYSNNFGIYPTDSSLPGDRGQIVLQADKAYNKKILHASWHPFEDSVAIAATNNLFVFSK......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 462
54 -49.300[T] KOG1354 Serine/threonine protein phosphatase 2A, regulatory subunit  ali follow..  14  1.MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELATGDKGGRVVIFQQEQENKIQSHSKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKVEASPRRIFANAHTYHINSISINSDYETYLSAD-DLRINLWHLEITDRVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLMENRPVETYQVHEDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 447
55 -49.100[S] KOG0294 WD40 repeat-containing protein  ali follow..  13  1....................................MPPEMEIIEATNEELLLGFKLIKSPTDGFTDSVKSYARSITSLA----VQWPWVASGGTDGRIFVYDMRTRKQSQIILSHAGRVNTLKFTPDLSLLLSGSDDGHMIATRVGSWT---KEYDWQKAHAGAVTHVSCHPSS-KLALSLGGDQVLNTWNLVNNLKNKATLDFQTGCLSWSKQGDHFTLSGPLVLEIWGIENAHVMRRIEMPSKPICITWL-DGNECLTGLDNGNIAWISLKDEDD-----TPPTFILAHEVRVKAIAYLNE--LATVSIAGQIKVWKIDMETRKLEEIARFMDCRPTDLGLLDLRQFGNVRPVEQRTKVEEKPKAKESDQSAKPAAPRGFVTIEYEQDKKLDAEKKKEKKKNKKDEESSEESNSSEDKENDDFSDSDSDVSSDHGHRKRKPMKREQQPTPASKGKAKQQ............................................................................................................................................................................................................................................................................................................................................................................................................ 431
56 -49.000[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  12  412RVKLNIDAEYLIPKLPSPRDLSMVYRGHTDLVRSVSVEPKGELVSGSDDKTVKIWEIATGRCIRTI----ETDEVVRCVAWCPNPKLSIIAVATGNRLLNAEADEQEKGVRVVITHFKPIRQVTWHGRGDYLATVMPEGANRSALIHQLS-KRRSQIPFSKSKGLIQFVLFHPVKP--CFFVATQHNIRIYDKQELVKKLLTNSKWISGMSIHPKGDLLVSTYDKKMLWFDLDSTKPYQTMRLHRNAVSVAFHLRYPLFASGSDDQAVIVSHGMVYNDLLQLIVPLKKLQTHEKGVLDVNWHPVQPVFSTGADSTIRLYT.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 784
57 -49.000[DO] KOG0305 Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits  ali follow..  15  98.HQNPKPVKPRRYIPQNSERLDAPGLRDDFSLNLLDWGSANVLAIAL-GDTVYLWDASSGS-TSELVTIDEDKGPVTSINWTQ--DGLDLAVGLDNSEVQLWDCVSNRQVRTLRGGHE-SRVGSLAWDNHILTTGGMDGKIVNNDVRIRSS---IVETYLGHTEEVCGLKWSESG-NKQASGGNDNVVHIWDRSLWLHRFEEHTAAVRALAWCPFQALLATGGDGKIKFWNTHTGACLNSVETGSQVCSLLWSQSERELLSSFTQNQLTLWKYPSMS-------KMAELNGHTSRVLFMAQSPNGCVASAAGDENLRLWNVFGEPPKT---TKKAASKKYPELFSHVNSL............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 443
58 -48.900[S] KOG0283 WD40 repeat-containing protein  ali follow..  12  369DHKHGKANEWVKVRELSALHMCQEIQAHEGAVWTIKFSQDAHLASGGADRVIHVWEVQECE---LMSMNEGSLTPIHPSLCDS--SGNEITVVEKKKKGKGSSGRSDKPVCSLKGHLDAILDLSWSKSQL-LLSSSMDKTVRLWDIETKT-----CLKLFAHNDYVTCIQFSPVDENYFLSGSLDAKIRIWSQDRHVVEWSDLHEMVTAACYTPDGQALIGSHKGICRAYDTEDCKLSQTNQIDRKITSFQFSPVNPEVLVTSADSRIRILDGSEVI-------HKFKGFRNTCSQLSASYSQDGKIICASEDSQVYLWKNDFHRTRSTLTTQSHEHWHGHVRGEPPPVQIHSKRHSKRISTS--SQPSSTISSPTKEETSATGPTTSNRNKKSGLPPMPKKAATKSQIQPEEEAGPELGSSESFRSSMNSSEQHSSRFGESPSINTSSRLSSWSWFDSGGH---------------PQTIQPTAWGMVIVTATVHGEI....................................................................................................................................................................................................................................................................................................................................................................... 884
59 -48.800[A] KOG0640 mRNA cleavage stimulating factor complex; subunit 1  ali follow..  12  89ALAPEPHSYETA-----------YVTSHKQACRAGAFSCDGSVATGSVDASIKILDVERMLAKSAIRTLYDHTDEVSYLEFHP--KEHILASASRDGTVKLFDIAKPSVKKAVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQC--VSAIPSQQHKAGVTCVKYSPTG-KLYATGSYDGDIKIWDSGRCINTIAEAHGAICSLEFTRNGKLLSSGMDSLVYLWELCTSRPIQTYTGAGTTEAVFNHTEDYVLFPDEATTSLCSWNSRNGC------RLTLNSLGHNGPVRYITHSPNGPFLTCSDDFRARFWYRRANNQ.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 424
60 -48.800[R] KOG2096 WD40 repeat protein  ali follow..  9  2.................................DSVLVVGIAVILGALIAVLFFGSYFRK---RTSEVQSMAKAEPQDPIRNP--KSNHPAPKKNHPKSQASDKNQNKRLNTLKGHGDAVTGLCFSSDGKSLATACADGVIRVFKLDDASLKFRFLRINLPAGGHPTAVAFADDASSIVVQGKLPLPSIKWDHIHEKRSVLTISGATATYGTADGSVVISCSEGTDIVLWHGKTGRNLGHVDTNQLKNMAAVSPNGRFLAAAAFTADVKVWEIVYQKDGSVEVSRVMQLKGHKSAVTWLCFSPNSEIITASKDGSIRVWNINVRYHLDEDDSGGNPLHYDRLSLCPEGKILAASHGSTLQWLCAETGNVLDTA--EKAHEGDITCISWAPKAMVLGTSGDDKKVKLWEAPKSQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 452
61 -47.300[DK] KOG0973 Histone transcription regulator HIRA, WD repeat superfamily  ali follow..  9  2.......................TFVGHDTGILAIDCHPSGKFITCGSNGLVVVWNAESNENVPKLLFQVESQSQSNSCRWSP--DGKRFAFGSDDSSVSVWEYVGLKECCVLRGHSMEVLTVEWSPNGKYLASGSIDYRIIIYNARKLPD---RITVLNDIQLPVKGLSWDPIG-KYLASLEGDKKLRFWATDSWQCV-NIEETMLTRLDWSPDGKYLMTPAAPLIKLIQRQTWKSDQFLAGHHKGTTCV-RMQLTCAAVGSRDKSISIWVFPGTLK---------FVINNIFNHTVMDFAWCGRLLACSQDGTVKVIHLSESVIGEMISNEAMSDLCYQIYSIRPPRYELTDKEEDESQDSFNLSDLSSSANNASFVTCPEDVLIKRKKLVAAQQSSDIQLTKSMEDNSKENESKNSEKTMMEERNKQ------IDVRKDG----------------------KRRIQPVFCGTTTADPMTSLSSEGKKTVAPPPAKRKALAPAVPAKKGEVDLEDSSDSDDDDEEEEEDMEISDIESVRNKKRKVPATTSQPMLALDLKKPALRPMEPKSLKTQEGTVLMEAPEQQPKLSQHVVDRKGMFVE------DNRWKHGGVETTQIKLIKKKQQTAENEDDMMDGERRVNHECLWMAVLGSPVIIVA-VVLGCGDKCLRVYRTFCGTHIVSLRLDSLPVLIGVTEHAAYALTENGRLST--------LKLGKAVVTRQPLFDCVEASTDNSLISADVSETGVPLIVCSNGTTNSAGPLVRLLKRMRKQATAPGVAPQVVKAVKESQLLHCAEQLGNPQDYQTM-----LMLYVETLCEGGSEKKLKNILNDLSALYDDV 898
62 -46.600[A] KOG0272 U4/U6 small nuclear ribonucleoprotein Prp4 (contains WD40 repeats)  ali follow..  12  127QINVSTDDTEIKSNLRQLNEPLKELLAGLGENAINKRQYEDERKQQQREQDQATWYHEGPDSLRLWLADYSLPRAKDRLVRAR--EALEVPSAARAGRMVEKKLQSLAPLCSQVGDTRPVSSAAFSEDSSLLLTSSWSGLCKLWSVPD----CELKQTLRGHASYVGGVALRPGVKAAMASGGHDGAVKLWGNEESIADITGHPHRVSKVAFHPSGRLATACYDSSWRLWDLEQKTEVLHQEGHAKPVCLSYHSDGSVLVTGGLDAFGRVWDLRTGR-------CIMFLEGHLGAVFGVDFSPNGFIATGSQDNTCKIWDLRRRQPV--YTIPAHTNLISDVKYQQEGSFLVTCSYDSTTKIW--SNKTWQPLKTLQGHDNKVISVDIAPNSQYIATTSFDRTFKLWS.................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 550
63 -46.300[S] KOG4328 WD40 protein  ali follow..  11  187.SIPVKPEKIEFDLDLLTLEPQNVARVVPGRIFVVQFLPCENVAAGDKLGNVGFWNLDCGNEEDGIYLFTPHSAPVSSIVFQQ-NSLSRVISSSYDGLIRLMDVEKSV-FDLVYSTDEAIFSLSQRPNDEQLYFGQDYGVFNVWDLRA----GKSVFHWELHERRINSIDFNPQNPHVMATSSTDGTACLWDKKPKTLSTVNHSRAVHSAYFSPSGLLATTSLDNYIGVLSGANFENTCMIYHNNTKFKAVWGWDDSYIYVGNLSKKIDVINPKLKRTVMELHNPLQR-----AIPCRIHCHPYNVLAGSTAGGQVYVWTTK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 516
64 -45.900[R] KOG2321 WD40 repeat protein  ali follow..  8  68AMATGVYKPHIKVFDFAEMSLKFERHTDAENVQFEILSDDWTSVHLQTDRTVDFHSQGGIHYSTRI------PKYGRDLKYHY--PNCDLYLAAAGDEVYRLNLEQGRFLNPLKSPTGGVNVIDINPMHQLLAFGTDAGSVEFWDPRDRSPSTVPSTPYSDNSRSVTALKYRNDG-LNVAIGLSDGATLLYDLRSYMSKDQGYSMPIKSLHWMDSALRVLSADSKIIKIWEKDTGKPFSSIEPTVELNDVCPIEGTGLILTANEGSPMHAFYIPSLNPAPRWCSFLDNITEEMEENPAPTIYDDYKFVTKKELLNLGLDHLVGTGVIRA----MHGFFIDNNLYEKARLIANPFSYEEHRQKIVKERLEKQRASKIRSQN--------------RPKVNAGLASRLSYQENKLRKKTGVTDGPSILEDERFKNVFEFEVDEDTLEYKQ------HPSRSEARGLTAAEESEEEKEHTKGIKFSSDEESLSDMEEENET........................................................................................................................................................................................................................................................................................................................................................................ 559
65 -45.300[R] KOG1188 WD40 repeat protein  ali follow..  11  42LVAVLCSNGSIRIYDKERLNVLREFSGYPGLLNGVRFANSCDVYSACTDGTVKCWDARVAREKPVQLFKGYPSNIFISFDINC--NDHIICAGTEDALLVFWDARMNSLGAYSETHSDDVTQVRFHPSNNMVVSGSSDGLVNVFDINIDNEE-DALVTTCNSISSVSCIGWSGKGYKQIYCMTHDEGFYWWDLNHVVNMKEDALDYLIGGLYHEKTDVIGGTNKGRIHLMNCSMSGVTSLQGGHAATVSFCWNVQDDSLLTGGEDAQLLLWKPGAIEK-------TFTKKESMKIASSVHQRVRVHSNDSYKRRKKQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 387
66 -45.200[R] KOG2444 WD40 repeat protein  ali follow..  10  4..........................EFDNPPLCMKSNKDGSLVVGFVDGSIRFYDTQQHEEEFQEIWKFQTKSSIRGVDLDE--HKKRVYAVTKNRSLCVFDIDTGKRVRCIKCHRSVPTAICTLPKSQQLATADESGEVKTWNLDPEVSENANIRKWQEQDEDINDLKVDVK--SNLLATSSDGTLGAYDKAKLKMRSELMHSELYSVC-GTNRSVYVGGEDGYVEVFNLNENLLERVESGFEMGVGIVELRSGLLGLTSQGSNRMRLLNVQPSKRLGYAGYHGD-EKSDDDGIDAITISTDKSFTMISMSCTIKKWDMGP---IIDEIPILRAQDAKSKKMRKTEGFFDGLVGPKNDSDSDDDDEPKSKKRRNDEDSDEEIDEEEQEEDDEEEEEDSD......................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 383
67 -45.200[R] KOG1273 WD40 repeat protein  ali follow..  12  2.........NAPIIDPLQGDFPEVIELEHGVIKCVAFNHRGSLAAGCADGGCVIWDFETRGIAKEIR--NDCSAAITSVSWSK--YGHRLLVSAADKSLTLWDVSTGEKIARTIPLSSAPMIVDFDIDCTTLLPVSVPEMPDVLAPPQ-----RSKCPESNPPFSPAAACFNKCG-DLVYIGNSKGEILIVDYKSLALVSASGAAPVKNIVFSRNGQLLTNSHDRTIRIYENLLPAKNKMKTVGSKCLAPCFSGDGEWVVGGSGEHKIYIWDRAGH--------LVKILEGPKEALIDLAWHPVHPIVSVSLAGLVYIWAKDYTENWSA--APDFKELEENEEYVEREDEFDLIPETEKVKVL--DVNEDEEVDIDTVEKDAFSDSDMSVEELRYLPAEPIPDT...................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 426
68 -44.700[R] KOG2055 WD40 repeat protein  ali follow..  8  154.AKKQDVTEEEDEFNALSEKSVIPKSLKSLFKSSVSYINQSSLLAPGTINIKRLKDANFQA---------PSHSGIRCMSIHP--YFPLLLTCGFDRTLRIYQLDVNPLVTSLHLRSSALQTALFHPDGKRVIAAGRRKYMYIWDLESAQVQKVSRMYQENFQPSMERFHVDPTG-KYIALEGRSGHINLLHTGQFATSFK-IEGVLSDVLFTSDGSMLVLSYGAEVWHFNVEQRSVVRRWQVQDGVSTFCLDPSNKYLAIGSKSGIVNIYDLQTSNADA-APKPVTTLDNITFSINSMSFSQDSQVLAIASKDTLRLVHVPSFSVFRNPTSATPLGRVTCLAFGKGGELCVGNEAG---RVGLWKLAHYDLKFVPDKII--NWEIRLGKFGYVLLGIQILIL....................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 549
69 -44.600[R] KOG1310 WD40 repeat protein  ali follow..  14  23.SHEVDQRMQFHSSLVRRLSQEQELEGHQGCVNALAWNSNGSLISGSDDLRINIWNYSSRK--LLHSIDTGHTANIFCTKFVPETSDELVVSGAGDAEVRLFNTSRLSPSALYQCHTRRVKKLAVEPNPNVVWSASEDGTLRQHDFRESTSAKRALADPPKQTLSLKSCDISATRPHLLLVGGSDAFARLYDRRMLLSERGRTNLHLTHVTFSPNGEVLLSYSGEHVYLMNVGAIDMKRRYVGHCNV-ASFLGQRGEYIASGSDDGRWFIWEKQTGR-------LMKVLVGDESVLNCIQCHPFDSVATSGIDNTIKIWSPTASV--PSIVAGGSAGPATANVVEVMESNQQKLSRNRENPLSVELMQRFRMQEFAEGNFH............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 747
70 -44.600[R] COG2319 FOG: WD40 repeat  ali follow..  15  204.DLAIGLAENIYLWSKELGPT-RVLEESIYDVSSVAYSYNGDLAVGRVDGTLQFWQDNERV----PRISIHHPGDIGVLAWKPVLETNRLLVGKGNGNIFVYDIIAVLVATITNAHDEQVCGLTWNHDGSQFASGGNDNRVCLFKGSDLRQ----PLYVWQQNAAVKALSFCPWQRSLLATGAHDKHIRFYNNGKKIDELYCGAQ-ITSIHWSPKYREFSVTVQHRFAVYSWPQLECLVSVLPSVPD-TTGRCEMTDSIIIASSNETIKFFDLSEESSWH----NSRVLTWHGIFDSQILEMLEG--IDGKIDSHLR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 535
71 -44.000[R] KOG0322 G-protein beta subunit-like protein GNB1L, contains WD repeats  ali follow..  13  31.LLAGTIKGSVFLWDLQTNRSALHFEVGSDPITSLHHTPDR-LVTQEKGGTITMFSIGGSSYVKERSIPGNHRSALHTNTSKT--NEQLLFYPCEESSIGVLHVTDAAAPTQILVPDDPCFKPFECASQLFLLAGYESGHFLTWDISSSV-----ILDVMELAQDATSVDYDPVT-NRGIVGGPTDKLISFSYQQLGSELCIKNPGVNGVRIRPDQKFASAGWDGRIRIFSWKSLRPLAVLTQHKNGGVMDLAFSAPIMAAAGMDGQISLWDLYN....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 323
72 -43.400[KL] KOG4283 Transcription-coupled repair protein CSA, contains WD40 domain  ali follow..  14  16.NSFANRFKSRRILSLQLSNRKDFVSPHRGSVNSLQVDLGRYLLSGAADGSAAVFDVQRATDYEAKQHENGHKYAISSAIWYPI-DTGLFITGSFDHYLKVWDTNTAQAVVDFKGKVYRTAMSSMAMSHTLIAAGTEDVQVRLCDIAS----GAFSHTLSGHRDGVMSVEWSTSSEWVLYTGGCDGAIRFWDRAGCFRVLDQS---QTQLGFRPPILRTAVGSKVC........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 253
73 -43.000[R] KOG2919 Guanine nucleotide-binding protein  ali follow..  10  106YFQGALVELGRRCWTSST--------EAQHYTKGCYWSPDGTLLVPVHLDGMHVIEMPSDLYSADTVVHVPEGGTVYDCVWYPQPETCLWLATRQHEPIHMWDAFDGSLRCSYSGYDMAAISLAFSHDGEQIYAGY-KRCIKIFDTSRPGR----FCDDYPVKFAISCIAQTTAHPHTLTCGNWHGYIQHFDLRCPLFTLGGHKGGITQLRYGEFGNFSGARKCDKILQWDMRYKQPLVELQRHVDTIQFDLASDSNWLASGDTRGFVNVWDLKKYGD-------PSVLPLHSDCCNGVALNPAMPILATSSGQ--FHFTDQSAQ--GDNVTLNGTETTELPAPADVNQNQKEVLYENAVVMWWCGQTG......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 487
74 -42.600[D] KOG1036 Mitotic spindle checkpoint protein BUB3, WD repeat superfamily  ali follow..  10  1............MTTVTPSAGRELSNPPSDGISNLRFSNNSDLLVSSWDKRVRLYDVSTNSLKGEF----LHGGAVLDCCFHD--DFSGFSVGA-DYKVRRIVFNVGK-EDILGTHDKAVRCCLFCDVTGQVITGSWDKTVKCWDPRGASGPE--RTQVGTYLQPERVYSMSLVG-HRLVVATAGRHVNIYDLRNEQRRESSLKYQTRCVRCYPNGTYALSSVEGRVAMEFFDLSEAAQAKK--YPVNSIAFHPIYGTFATGGCDGFVNIWDGNNKK-------RLYQYSKYPTSISALSFSRDGQLAVASSYTAIFVRSVNEIEVKP--KPKVYPNPAA...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 354
75 -42.500[A] KOG0647 mRNA export protein (contains WD40 repeats)  ali follow..  10  10TSALGTSTAMANEKDLAND--IVINSPAEDSISDIAFSPQQDFSASSWDGKVRIWDVQNGV--PQGRAQHESSSPVLCTRWSN--DGTKVASGGCDNALKLYDIASGQ-TQQIGMHSAPIKVLRFPSNTECIVTGSWDKTIKYWDMRQ----PQPVSTVMMPER-VYSMDNKQSL--VVATAERHIAIINLATTIFKATTSPLKWQTRCVACYNEADYAIGSVEGRCSIRYIDDGMQKKS-SLVYPVNSIAFHPLYGTFVTAGGDGTFNFWDKNQRHR-------LKGYPTLQASIPVCSFNRNGSFAYALSYDWHQGHMGNRPDYPNVIRLH----ATTDEEVKEKKK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 364
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.