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Query: [O] KOG0550 Molecular chaperone (DnaJ superfamily), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTEVETTHMNAGTESQQEPAELAEKQKAIGNAFYKEKKYAEAIKAYTEAIDLGSDSALAIYYSNRAATYMQIGEFELALCDAKQSDRIKPDVPKTQSRIRQAYEGLSILNEAEVYLKNKQAGLALNALDRLQRRIDSTTQPPMSWMYLKAQVYIFQNDMDRAQKIAHDVLRLNPKNVEALVLRGKVMYYSGENAKAITHFQEALKLDPDCTTAKTLFKQVRKLENTKNQGNDLFRQGNYQDAYEKYSEALQIDPDNKETVAKLYMNRATVLLRLKRPEEALSDSDNALAIDSSYLKGLKVRAKAHEALEKWEEAVRDVQSAIELDASDANLRQELRRLQLELKKSKRKDHYKILGVSKEATDIEIKKAYRKLALVYHPDKNAGNLEAEARFKEVGEAYTILSDPESRRRFDSGVDLEPGMEGGAGMDPFDILRAYQAGGSFPGGGFPGGGFPGGSYNSQGFGMGGGFPGFTSFQFSLast
1 -114.000[O] KOG0550 Molecular chaperone (DnaJ superfamily)  ali  100  1MTEVETTHMNAGTESQQEPAELAEKQKAIGNAFYKEKKYAEAIKAYTEAIDLGSDSALAIYYSNRAATYMQIGEFELALCDAKQSDRIKPDVPKTQSRIRQAYEGLSILNEAEVYLKNKQAGLALNALDRLQRRIDSTTQPPMSWMYLKAQVYIFQNDMDRAQKIAHDVLRLNPKNVEALVLRGKVMYYSGENAKAITHFQEALKLDPDCTTAKTLFKQVRKLENTKNQGNDLFRQGNYQDAYEKYSEALQIDPDNKETVAKLYMNRATVLLRLKRPEEALSDSDNALAIDSSYLKGLKVRAKAHEALEKWEEAVRDVQSAIELDASDANLRQELRRLQLELKKSKRKDHYKILGVSKEATDIEIKKAYRKLALVYHPDKNAGNLEAEARFKEVGEAYTILSDPESRRRFDSGVDLEPGMEGGAGMDPFDILRAYQAGGSFPGGGFPGGGFPGGSYNSQGFGMGGGFPGFTSFQFS 476
2 -82.500[V] KOG0624 dsRNA-activated protein kinase inhibitor P58, contains TPR and DnaJ domains  ali follow..  21  5.QHLLILWSSLFASTFAGTAEEVAKHLELGSQFLARAQFADALTQYHAAIELDPKSYQA--IYRRATTYLAMGRGKAAIVDLERVLELKPDFYGARIQRGNILLKQGELEAAEADFNIVAGGDCATVEEYINHIIEIQVWDA-SLYRMRAKCLEERGELKKAIHDMRIVSKLSTDSTDTMFETSKLLYTVGDLEESLNVIRECLKLNPDHKSCYPFYKKLRKVVKSLESMKKKVENSDWMACLEEGQKTMKFDPTP-SVQLNVFRITNRCQREAGHISEAIAECNEILNDDPSDADILCERAEAHILDEDYDSAIEDYQKATEVNPDHREAKEGLEHAKRLKTQAGKRDYYKILGVKRNASKREITKAYRKLAQKWHPDNFSDEEEKKKAEKKFIDIAAAKEDEEKRRQFDQGVD---PLDPEAQRQGGGHHGGFGHGFPHGFHHFGGGGGGEHS---------------FKFNWG 491
3 -71.800[O] KOG0548 Molecular co-chaperone STI1  ali follow..  14  15.SGDFTTAINHFTEAIALAPTNHVLFSNRSAAHASLHQYAEALSDAKETIKLKPYWPKG--YSRLGAAHLGLNQFELAVTAYKKGLDVDPTNEALKSGLADAEASVARSRAAPNPFGDADFVNMMQEIQKNPSSLNLYLKDQRVMEKELGNAAYKKKDFETAIQHYSTAIEIDDEDISYLTNRAAVYLEMGKYNECIEDCNKAVERGRELRSDYKMVARAQKALTEHRNPDTLKRLNDAERAKKEWEQKQYFDPKL----GDEEREKGNDFFKEQKYPEAIKHYTEAIKRNPNDHKAYSNRAASYTKLGAMPEGLKDAEKCIELDPTFSKGYSRKAAVQFFLKEYDNAMETYQAGLEHDPSNQELGVKRCVQQINKANRGDLTPEELKERQAK-GMQDPEIQNDPVMRQVLSDLQENPSAAQK----------HMQNPMVMNKIQKLISAGIVQMK.................... 572
4 -65.200[U] KOG0547 Translocase of outer mitochondrial membrane complex, subunit TOM70/TOM72  ali follow..  13  102.YPSLPNGEPDIAQLKGLSPSQAVQLKNRGNHFFTAKNFNEAIKYYQYAIELDPNEPVF--YSNISACYISTGDLEKVIEFTTKALEIKPDHSKALLRRASANESLGNFTDAMFDLSVNTSSNYDTAYALLSDALQRLYSATDEYLVANDLLTKSTDMYHSLLSANTVDDPLRENAALALCYTGIFHFLKNNLLDAQVLLQESINLHPTPN-------------SYIFLALTLADKENSQEFFKFFQKAVDLNPEY----PPTYYHRGQMYFILQDYKNAKEDFQKAQSLNPENVYPYIQLACLLYKQGKFTESEAFFNETKLKFPTLPEVPTFFAEILTDRGDFDTAIKQYDIAKRLEEVQEK---IHVGIGPLIGK------ATILARQSSQDPTQLDEEKNAAIKLLTKACELDPRSEQA----------KIGLAQLKLQMEKIDEAIELFEDSAILARTMDEKLQATTFA.. 607
5 -61.600[R] KOG1129 TPR repeat-containing protein  ali follow..  13  6.DSTYVDELENEDMGLALDQNVIAPNARPGTSFARPKTSAKGVNPILRPT-TNAGRPLS--GVVRPQSSFKSGSMDQAVRTARTAKTARAVSSTSARNMRLGTASMAA-------------GADGEFVNLARLNIDKYAADPQVNRQLFEYVFYYLNDIRVAHQIAGTASKAAGEDYYWKNQLAKCYLRLGMLQDATKQLQSSLEQKKL-------------IETFALLSKAYNRVDQPMAALKTYSAGLEVFPEN----VTMLTGMARVQEALGEYDESVKLYKRVLDAESNNIEAIACVATTYYYGGKPELAMRYYRRILQMGVSSPELFLNIGLCCMAAQQFDFALSSILRAQSTMTDDVA-ADVWYNIGQILLVSAARSFRIALSHDPDHSESLVNLG-DEARSLYSSATSKNPYMFEG----------NYNLGLVSFTQGKYHECRELIEKALAAFPEHEHCKKILN.... 449
6 -60.300[S] KOG4648 Uncharacterized conserved protein, contains LRR repeats  ali follow..  14  1........MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLLDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYT---------------KGMDADPYNPVLPT-NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKIQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGAN----ALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHQRQNVVKPIDNPP---HPGSTKPLKKVIILIQTIDVPDSTTAAAPENNPINLANVKKNSSQDVLFPTSDTPRAKVLKIEEPPIPANSFQLESDFRQLKSSPDMLYQYLKQIE................. 574
7 -59.400[DO] KOG1173 Anaphase-promoting complex (APC), Cdc16 subunit  ali follow..  12  337.RDHDTDTLIPIAECLDRVQRSTDLMAAEAEKCFYDCDYKQCLKILNELLKVDPFHNTA--LTIQIACLVENGDFNRLFYVAHKLVDRYPDKAISWYAVGCYYDMIGKSDPARRYLS---------------KATALDRLYGPAWL-AYGHSFANENEHEQAMAAYFKATQLMRGCHLPLLYIGVECGLTKNLELAEKFFLQAMNIAPLDVYV------------LHELGVIKYEYEFFDGAATIFQCTVDIVKQRAKSNEPLFINLGHSLRKVHKYEEALYNFQYALLLKPQSPTTYTSIGFIHALLGNLDPAIEAFHKSLALNRDCIVTSTILKSCIEDLMDDSATIDEICSAALRDVAKN---ITANSRRVLNSDK-----------------------FNGMKLKFDEEEEFANSDSNMVVEMS................................................ 715
8 -58.700[B] KOG1156 N-terminal acetyltransferase  ali follow..  12  23.HKQYRNGLKFCKQILSNPAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVC--WHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQEDYEMAAKILEEFRKTQQTSPDKVSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERYKDKEKVAIIEELVVGYETSLKSCREPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQTLRSYVDLLKLE----DVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDK.......... 590
9 -58.400[DO] KOG1155 Anaphase-promoting complex (APC), Cdc23 subunit  ali follow..  13  156INRELVSLERDLSALRRTGAIDSFGLYLYGVVLKEKGNESLARASLVESVNSYPWNWSAMKEFFLGNAYQELRMHTESLAKYEYLQGIFSFSNYIQAQTAKAQYSLREFDQVEIMFE---------------ELLRNDPYRVEDMD-LYSNVLYAKEACAALSYLAHKVFLTDKYRPESCCIIGNYYSLKGQHEKAVMYFRRALKLNKKYLSAWTLM------------GHEYVEMKNTPAAIDAYRRAVDINPTD----YRAWYGLGQAYEMMGMPFYALHYFRKSIFFLPNDSRLWIAMAKCYQQLYMLEEAIKCYKRAVNCTDTEGIALNQLAKLHQKLGRNEEAAYYFEKDLERM------------------DAEGLEGPNMFEALVFLATHFKNHKKEEAEVYCTRLLDYSGPEKEKAKS----------RGIRMAQTGFPSMDLEHFP..................... 578
10 -57.500[DO] KOG1174 Anaphase-promoting complex (APC), subunit 7  ali follow..  12  21LLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSVKYKMAECYTMLKQDKDAIAIL-DGIPSRQRTPKINMMLANLYKKAGRERPSVTSYKEVLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDLYLIKGMDVY------------GYLLAREGRLEDVENLGCRLFNISDQH----AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLETQEKAKTLLDKALTQRPDYIKAVVKKAEEDGIALLRNALANQSD-----------CVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQ.... 516
11 -56.200[T] KOG4162 Predicted calmodulin-binding protein  ali follow..  12  354LLLLIAEALAVRDTVLSQSPEFRQAYDLLTLATVRWGLVQLLNESFEKALKFSFGEQHV--WRQYGLSLMAAEKHSHALRVLQESMKLTPSDPLPCLLASRCYESLETVKQGLDYAQQALKREVKGLRPSRSQLFVGIGHQQLAI--QSNLKSERDACHKLALDALERAVQFDGNDHLAEYYLSLQYALLGQLAEALVHIRFALALRMEHAPCLHLF------------ALLLTSSRRPREALGVVEDALHEFPDN----LQLLHVKAHLQLHLEDAETALGTVQHMLAVWRDQIEIWLLLADVYLRIDQPNEALNCIHEASQIYPLSHQIMFMRGQVHVYLEQWFDAKQCFLNAVAANPNHTE-------------------------ALRALGEAHLVLGERLAEKMLKDAAKLDPSCPKI----------WFALGKVMEILGDFHASADCFATSLQLEPSCPVLPFTS..... 855
12 -55.600[R] KOG1124 FOG: TPR repeat  ali follow..  10  23.SLSFLTPQIPENLCKSPTKIHIGTHGISGQSFLSHPTFSSKNTYLYAVVDRSSSGV-FSPQKESANGEGEESNTEEGVLVVRRPLLENSDKESSEEEGKKYPARIDA-KKMPIFEPERSESSSSSSAAAAARAQERPLAVNLDLSLYKAKVLARNFRYKDAEKILEKCIAYWPEDGRPYVALGKILSKQSKLAEARILYEKGCQSTQNVRRARELFDAAKHVAAWHGWANLEIKQGNISKARNLLAKGLKFCGRN----EYIYQTLALLEAKAGRYEQARYLFKQATICNSRSCASWLAWAQLEIQQERYPAARKLFEKAVQASPKNRFAWHVWGVFEAGVGNVERGRKLLKIGHALNPRDPVLSLGLLEYKHSSANLARALLRRASELDPRHQPVWIAWGWTTARELYQRALSIDANTESA-------SRCLQAWGVLEQRAGNLSAARRLFRSSLNINSQSYVTWMTWA.... 519
13 -52.000[D] KOG1126 DNA-binding cell division cycle control protein  ali follow..  15.NQNYDNSIFYSERLHAIEDSN-ESLYLLAYSHFLNLDYNIVYDLLDRVISHVPHPDASCMLDVLGTMYKKAGFLKKATDCFVEAVSINPYNFSAFQNLTAIGVPLDANNKNLLAFNDAQKADSNNRDTSLKSHFVEPRTQALRPGARLTYKLREARSSKRGESTPQSFREEDNNELLKLFGKGVYLLAQYKLREALNCFQSLPIEQQNTPFV------------LAKLGITYFELVDYEKSEEVFQKLRDLSPSR----VKDMEVFSTALWHLQKSVPLSYLAHETLETNPYSPESWCILANCFSLQREHSQALKCINRAIQLDPTFEYAYTLQGHEHSANEEYEKSKTSFRKAIRVNVRHYN---AWYGLG----------------------MVYLKTGRDQADFHFQRAAEINPNNSVL----------ITCIGMIYERCKDYKKALDFYD..................... 557
14 -48.700[R] KOG0553 TPR repeat-containing protein  ali follow..  15  1...............................................................................................................................MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTEIFEAAATGKEMPQDLRSPARTPPSEED--------AEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPAN----AVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSGLLNNP---GFMSMASNLMQQLMSGMISGGNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQ---------QNPELIEQLRSQIRSRTPSASNDDQQE........................ 313
15 -47.300[R] KOG1125 TPR repeat-containing protein  ali follow..  14  305.QVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEA--WQFLGITQAENENEQAAIVALQRCLELQPNNLKALMAL--------------------------------------------------AVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRRMSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPED----YSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAIS-------------------------GNIWAALRIALSLMDQPELFQAA--------------NLGDLDVLLRAFNLDP.......................................................... 626
16 -47.100[R] COG4785 Lipoprotein NlpI, contains TPR repeats  ali follow..  13  3.PFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVILARMEQILASRADDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFN--------------------------------------------------YLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLD--------------KQAKEVLKQHFEKSDKEQWGWNIVEFYLGNI-SEQTLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALLELSLLGQDQDDLAESDQQ......................................................................................................................... 294
17 -45.800[S] KOG4340 Uncharacterized conserved protein  ali follow..  10  55.ACLYPEATRVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSLVEQLLSGEGGEESTDGQVNLGCLLYKEGQYEAACSKFSATLQASGYQPDLSYNLALAYYSSRQYASALKHIAEIQLRNYEVAQETLTDMPPRAEEELDPVTLHNQALMNMDARPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLY-------------DALITCQTAPEEAFIKLDGLAGMLTEQLRRLTKQV-QEARHNRDDEAIKKAVNEYDETM---EKYIPVLMAQAKIYWNLENYPMVEKVFRKSVEFCNDHDVWKLNVAHVFMQENKYKEAIGFYEPIVKKHYDNILNVSA--------------------IVLANLCVSYIMTSQEEAEELMRKIEKEEEQYDDPNRKMYHLCIVNLVIGTLYCAKGNYEFGISRVIKSLEPYNKKLG.......... 542
18 -45.500[OT] KOG1308 Hsp70-interacting protein Hip/Transient component of progesterone receptor complexes and an Hsp70-binding protein  ali follow..  12  1MDPCKVNELRAFVKMCKQDPSVLHT------------EEMRFLREWVESMGGKVPPATQ--KAKSEENTKEEKPDSKKVEEDLKADEPSTEESDLEIDKEGVIEPDTDAPQEMGDENVEITEEMMDQAND---------------KKVAAIEVLNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIQDCDRAIEINPDSAQP--------------------------------------------------YKWRGKAHRLLGHWEEAAHDLAFACKLDYDEDASAMLKE-----VQPRAQKIAEHWRKYERKHEEREIKERIERVKKAQEEQERAQREEEARRQSGAHYGPFPGGFPGGMPGNFPGGMPGMGGDMPGMAGMPGLNEILSDPEEVMVAFQDVAQNPANMSKYQSNPK----------VMNLISKLSAKFGGQA..................... 369
19 -45.200[R] KOG1128 Uncharacterized conserved protein, contains TPR repeats  ali follow..  10  358VLIKDRLLRTSYILASGLTPF--QSSVLLAGILNSLGCTSEALLILEKL----------EMWDGVIDCYKQLGQMDKAETLIRRLIEQKPNDSMLHVYLGDITRNLEYFTKA----------------------IELSDDRNARAHRSLGHLLLMDKKFEEAYKHLRRSLELQPIQLGTWFNAGYCAWKLENFKESTQCYHRCVSLQPDHFEA------------WNNLSAAYIRHGQKPKAWKLLQEALKYNYEH----PNVWENYMLLSVDVGEFSQAIQAYHRLLDMNKRGADDEVLELIAQTLLRR--EAEISMDESEDKAQNEAENRKEKEEMIKLLARISANHQTLSPKTLRVYALLKKPSVLSSETRTEFEKYVRLLEKSLAAANGKLTWPKEEKLLEVVETAVRLAEDRLELAKFIASDTDKDSGSRVSGDETEKLQEIVEVAKSLLDSVAI................ 787
20 -43.300[S] KOG3060 Uncharacterized conserved protein  ali follow..  13  7.KMSWSDVRDQFRTWREETGRHSEEVVQLWVAVLE-----------DKVHKTGNERHLI--LEQVIIAALDTARFDIATKCTKQLSLEFPGSLRVMK--------------------------------------------------FKAMRYEALEQYDEADEVLDAIIAKDETNAAPRKRKIAILKARGRRLEAIKELNEYLKKFMSDQEA------------WHELCNMYLAEGEFGKAAFCMEEVLLHNPHS----HLIHQRLAEIRYTMGNMESARTYYSQALKLNPHNLRALYGIYLCCNHLDNSRAVSSKRKELQKLSQWALEQLLTKQTIVPLEAAFG--------NLEIKSN................................................................................................................... 282
21 -42.700[U] COG5010 Flp pilus assembly protein TadD, contains TPR repeats  ali follow..  15  21AMVALSLSACAGQQGRKELTTGSIPKLTRPVQSMNATELAAAAERIGQAYERNPKDREA--GLNYANLLRMTGRNEQALAVMQQVAIYHPADREVLGAYGKA--------------------------------------------------QAAAGQLEQALATISRAQTPDRPDWKLKSAEGAILDQLGRSAEARLRYREALDLKPNEPSV------------LSNLGMSYLLTKDLRTAETYLKSAASQPDAG----SSVRQNLALAVGLQGRFQEAETIAGQELTSEQAEANVAYLRS-VLSQQGAWKQLAKA............................................................................................................................................................... 268
22 -42.400[G] COG2956 Predicted N-acetylglucosaminyl transferase  ali follow..  10  3........................ELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSR--DYVAGVNFLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQT------------LMESASLTYEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDVAERLVKLGKDKQ-------RVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNS----ARVSIMMGRVFMAKGEYAKAVESLQRVISQDRELVETLEMLQTCYQQLGKTAEWAEFLQRAVEENTG-ADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKHLNEAEEGRAKESLMVLRDMVGEKVRSKPRYRCQK.......................................................................... 359
23 -39.600[NU] COG3063 Tfp pilus assembly protein PilF  ali follow..  13  14VLALGACSTSYRPSRAEKANQVSNIKTQLAMEYMRGQDYRQATASIEDALKSDPKNELA--WLVRAEIYQYLKVNDKAQESFRQALSIKPDSAEINNNYGWFLCG-------------------------------------------------RLNRPAESMAYFDKALATYPTPYIANLNKGICSAKQGQFGLAEAYLKRSLAAQPQFPPA------------FKELARTKMLAGQLGDADYYFKKYQSRVEV----LQADDLLLGWKIAKALGNAQAAYEYEAQLQANPYSEELQTVLTG............................................................................................................................................................................. 252
24 -39.400[U] KOG3081 Vesicle coat complex COPI, epsilon subunit  ali follow..  13  1...............MSAMGAGPDHLFNLRN-NFYLGAYQTAINNSEIANLSPENAVERDCLVFRS--YIALGSYQLVISEIDES---AATPLQAVKLLAMYLSTPQNKESTISSLKEW--------------LADSTIGNNDTLRLIAGIIFMHEEDYNETLKHTHA-----GGTMDLYALNVQIFIKMHRAEYAEKQLRVMQQIDEDHTLTQLASAWL----------NLAVGGSKIQEAYLIFEDFSEKYPMT----CLILNGKAVCCMQMGNFDEAETLLLEALNKDAKDPETLANLVVCSLHVGK--SSSRHLSQLKLSHPEHI-----VKRVSSAEDNFERAVQLVA........................................................................................................................... 293
25 -37.800[Z] KOG1840 Kinesin light chain  ali follow..  12  161.GDSTHKALELTHRAAKLCLEWIMCLHVTAAVHCKLKEYNEAIPVLQRSVEIEHALAKFAGLMQLGDTYAMVGQLESSISCYTEGLNIDPRVGETCRYLAEALVQALRFDEAQQVCET--------ALSIHRESGLPGSIAEAADRRLMGLICETKGDHENALEHLVLASMAESEVAFVDTSIGDSYLSLSRFDEAICAYQKSLTALKTAKG-----NHPAVGSVYIRLADLYNRTGKVREAKSYCENALRI-EISPEEIASGLTDISVICESMNEVEQAITLLQKALKIKIMIAGIEAQMGVLYYMMGKYMESYNTFKSAISKSTFFGIALNQMGLACIQLDAIEEAVELFEEAKCILEQE-------------------PYHPETLGLYSNLAGAYDAIGRDDAIKLLGHVVGVREEKLGT--ANPVTEDEKRRLAQLLKEAGNVTGRKAKSLKTLID................ 640
26 -37.600[U] KOG2376 Signal recognition particle, subunit Srp72  ali follow..  10  29.DTKYEEAVKVADQVLSIVPTDEDAIRCKVVALIKDDKFDDYLIKDVKINGALSNSFPIDLGFHKAYCLYRENKLDEALVCLKGL----ERESKTLLLEAQILNCLGKVDACVDVYQKLNKSGRAGKASQVLESLKIRPTTTYQLAYNTACSLIENSNYVDAEQLLLTAMRIETQLAPISVQLAYVQQVLGQTQESKSSYVDIIKRNLADESLALAVNNLVALK----------GSKDISDGLRKFDLLKDKDSQNHKHKEAIYANRVLLLLHANKMDQARELCATLPGMFPESVIPTLLQAAVLVRENKAAKAEELLGQCAENFPEKSLVLLARAQIAASASHPHVAAESLSKALRERAGDNDGATAVLDSAIRWWSDSMTDSNMLRILMPVAAAFKLRHGQEEASRLYEEIVKNHNS......................................................... 491
27 -37.200[S] KOG4555 TPR repeat-containing protein  ali follow..  16  1...........................................................................................................................................................MPQANLTLSPHDQQVLDSIFNP--LELSSLQTNNLIPAESDLKDEEPDTQ-------------AIKASRELELKAIALSESGELDGALELFQQSLNLAQ-----RASVLNNRAQTLRLAKRDEEALDDLNKALELANDQCHAHCQRGVLYRKLDNLEAARADFEAAAQLGSKFAREQLVEINPYAALQMLRQAFDQLK........................................................................................................................... 185
28 -37.100[A] KOG0495 HAT repeat protein  ali follow..  11  415.RAVECCNTSVLNKARENIPTDRQIWTTAAKLEEANGNIHMVEKIIDRSLTSLTVNGRKQTWIDDAEFCAKENAFECARAVYAHALQIFPSKKSIWLRAAYFEKNHGTRESLEALLQ---------------RAVAHCPKSEILWL-MGAKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPTPR--------------MMKSARLEWALEKFDEALRLLEEAVEVFPDF----PKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAGLKEIASTMMARALQECPNAGELWAEAKPQRKTKSVDALKKCEHDPHVLLAVSKLFWSEHKSKCRDWFNRTVKIDPDLGDA----------WAYFYKFELLHGTEAQQQEVLDRCISAEPTHGESW........ 884
29 -36.200[S] KOG2796 Uncharacterized conserved protein  ali follow..  14  47LLTAHGQGYGKSGLLTSHTTDSLQLWFVRLALLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHHAELQQYLGNPQESLDRLHKVKTVCSK-------------ILANLEQGLAEDGGMSSVTQEGRQASIRL-----RSRLGRVMYSMANCLLLMKDYVLAVDAYHSVIKYYPEQPQLLSGIGRISLQIGDIKTAEKYFQDVEKVTQKLDGLQ------GKIMVLMNSAFLHLGQNNFAEAHRFFTEILRMDPRN----AVANNNAAVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLLESSRSMQKKQALLEAVAGKEGDSFNTQ................................................................................................................................................ 374
30 -36.100[T] KOG1130 Predicted G-alpha GTPase interaction protein, contains GoLoco domain  ali follow..  12  1MREDHSFHVRYRMEA------SCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLQLGEAKASGNLGNTLKVLGNFDEAIVCCQRH----------DISRELNDKVGEARAL--NLGNVYHAKGKSFGCPGPQDVG--------------EFPEEVRDALQAAVDFYEENLSL------VTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQEEGRACWSLGNAYTALGNHDQAMHFAEKHLEIS-------------------REVGDKSGELTARLNLSDLQMVLGLSTNNSIMSENTEI----DSSLNGVLPKLGRRHSMENMELMKLTPEKVQNWNSEILAK................ 425
31 -34.000[S] COG3898 Uncharacterized membrane-bound protein  ali follow..  15  78................VRRRDRGYQALSTGMIAAGAGDGALARKKTKEAAKLIRSDQEPLIHLLEAQASLLEGDHEGARQKFESMLDDPEMRLLGLRGLYLEAERLGDRNAARHYAG---------------RAAAVAPQLAWAAE-STLEELTARGDWDGALKLVDAQKSTRQIERDAANRRRAVLLADSDPNAARTAALEANKLQPDFAPAAVAA------------AAALFKQNDVRKGSKILETAWRAEPHPE------IAELYTHARPGDAVLDRLNRAKKLQEMKKNHAESSMTVARAALDAQDFSTARSEAEAAIRMDRREGAYLLLADIEEAETGDQGKVRQLLSKAVRAPRD................................................................................................................... 395
32 -32.900[S] KOG4507 Uncharacterized conserved protein, contains TPR repeats  ali follow..  11  238IKNEPYQVVECAMRALHFSSRHNKALVNLANVLHRAHFSADAAVVVHAALDDSDF---FTSYYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSKEYQKQHDHYLRQQEILEKHKLIQEEIHETQMAKEAQLGNHQICRLVNQQHSLHCRWDQPVRYHRGDIFENVDYVQYLVKELEVRMDLKAKMPDDHARKILLSRINNYTIPEEEI-AVGNSTFAIACLQRALNLAPLQYQDVP--LVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTTKCPECENSLKLIREEEPSERGTEEDPVFSVENSGRDSDALRLESTVVEESNGSDEMENSDETKMSEEILALVDEFQQAWPLEGFGGALEMKGRRLDLQGIR-KKPKGDHKKTPGKKVETGQIENGHRYQANLEITGPKVASPGPQGL... 947
33 -32.900[R] KOG4234 TPR repeat-containing protein  ali follow..  34  100.........................................................................................................................................................................................................................KALAEANEAKAEGNKLFVNGLYEEALSKYAFALELVQELPELRSICYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFEDAVTDLKKILELDPSNDQARKGIRRLEPLAAEKREKMK.............................................................................................................................. 235
34 -32.700[O] KOG4642 Chaperone-dependent E3 ubiquitin protein ligase (contains TPR repeats)  ali follow..  17  5.EEKEGGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLV--AVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKA------------------------------------------------------------------------------------HFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQES-----------------ELHSYLSRLIAAERERELEECQRNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKIS-----------------FELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAF.................................................................. 293
35 -32.400[D] KOG1915 Cell cycle control protein (crooked neck)  ali follow..  11  104.NKSVNEARNVWDRAVSLLPRVDQLWYKFIHMEEKLGNIAGARQILERWIHCSPDQQ---AWLCFIKFELKYNEIECARSIYERFVLCHPK-VSAYIRYAKFEMKHGQVELAMKVFERAAFAEFEEQYKFALDQIPKGSKFVAFEKQNGDKEGIEDAIIGKRRCQYEDEVRKNPLNYDSWFDFVRLEETVGNKDRIREIYERAVANVPPPEAQEKRYWQRYIYLWINYAFFAEMVTEDVESTRDVYRACLKLIPHSKFSFAKIWLLAAQHEIRQLNLTGARQILGNAIGKAPKD-KIFKKYIEIELQLRNIDRCRKLYERYLEWSPGNCYAWRKYAEFEMSLAETERTRAIFELAISQPALDMPEL-----KTYIDFEISEGELERTRALYERLLDR-KKDGIKRAREIFDRANTYNKDSTPELKEE--RAMLLEDWLNMETGFGKLGDVRVVQSKLPKKVKK............. 607
36 -30.900[O] KOG0530 Protein farnesyltransferase, alpha subunit/protein geranylgeranyltransferase type I, alpha subunit  ali follow..  11  3................DSDIPSSTLYKDNVDWKDITPIYPSKEEEVAVKIAVTEDFTDA--FAYFRAILIKNEKSDRVMALLEDCIRLNPANYTVWQYRRVCLTELGWDLKKE--------------MRYLSDIIQESPKNYQVWH-HRRFIVETIGEVNDELHFCSEVIRDENKNYHAWQHRQWVVRTFKVPLEKELTFLHMLLLDNRNNSAYNYRYFL------MTLYDKTEDASQLDIEINLAKKFIENIPNNESA----YLAGLLITNGVTSNSDVVSFVEDLYETTPEEKRSPFLLAFIADMMESAGRAKKLYKDLQSIDPVRVNYYRHQSLLAQTMLIKAQTKVTAK........................................................................................................................... 328
37 -30.500[O] COG4235 Cytochrome c biogenesis factor  ali follow..  15  33.....................................................................................................................................................GVSYYQTGNY-QQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKNPGDIEGWIML------------GRVGMALGNASIATDAYATAYRLDPKN----SDAALGYAEALTRSSDNRLGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIERSIAQAMQHLSP................................................................................................................................ 217
38 -29.100[H] COG3071 Uncharacterized enzyme of heme biosynthesis  ali follow..  12  96AEGDFLQVEKLLTRNADHAEQPMVNYLLAAEAAQQRGDEFRTNQYLERAAEVADGDQLPVNIT-RVRIQLAQGHIHAARHGVDRLLDQAPRHPEVLRLAEQAYLRSGAYRSLLDILPAMSKTQIHTP--------EEVAALEQQAYIGIMNQCMADEGSEGLKRWWKDQSRKVRNEIPLQVALAEHLIECDDHDVAQKIILDSLKHQYDERLALLIPR---------------LKAGNPEPLEKSLRQQIKQHGAT----PLLNSTLGQLMLKHGEWEKASEAFKAALAQRPD-GYDYAWLADALDKLHRPEDAAQARREGLLLTLRQNGESSALTKLIH........................................................................................................................................ 406
39 -27.900[O] COG5536 Protein prenyltransferase, alpha subunit  ali follow..  1...............MDPIDPELNEILDFTEYGPLTPIPQDDGENPLAKICYTTGYEQG--MAYFRAIMAKKEYSLRALNLTGFLIMNNPAHYTVWAYRFQILNHTPS-------------------------------------------------YIDNELEWLDEIAEDFQKNYQVWHHRQKILSLTKNYERELEFTKKMFEIDSKNYHV------------WSYRVWILQNFNDYSQELKLTNELLEKDIYN----NSAWNHRFYVLFETSKLEEELNYLKDKILFAPDNQSAWNYLCGVLDKSGKLDNLIANLRKNLPALHKPLLEFLAMYEPSSSEEIYQKL------ANEVDVPHAA---LWTWMSQRSNP.................................................................................................. 294
40 -27.500[S] KOG4814 Uncharacterized conserved protein  ali follow..  136LIQRSSPEADLTMEKITVESDHFRVLSYQAESAVAQGDFQRASMCVLQCKDMLMRLPQHHLCYNFGVETQKNNKYEESSFWLSQSYDIGKMDKKSTGPEMLAKVLR-----ATNYLDWDDTKYYDKALNAVNLANKEHLSSPGLFL--KMKILLKGETSNEELLEAVMEILHLDMPLDFCLNIAKLLMDHERESVGFHFLTIIHERFKSSENIGKVL--ILHTDMLLQRKEELLAKEKIEEIFLAHQTGRQLTAESMNWLHNILWRQAASSFEVQNYTDALQWYYYSLRFDLDFTKLQRNMACCYLNLQQLDKAKEAVAEAERHDPRNVFTQFYIFKIAVIEGNSERALQAIITLENILTDEES................................................................................................................ 503
41 -27.500[O] KOG0551 Hsp90 co-chaperone CNS1 (contains TPR repeats)  ali follow..  17  12............................................................................................................................................................DVMDSFLEKFQSQPYRGGFHEDQWEKEEKVPLFMSRAPSEIDPRENPDLACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKADKLKRIEQRDVRKANLKEKKERNQNELLQAIKARNIRLSEAACEDEDSASEGLGELFLDYPEYAQSDFISAFHEDSRFID.......................................................... 302
42 -27.000[R] COG0457 FOG: TPR repeat  ali follow..  14  448.KEITPEHEIALTEAFYHAEDLLKWFISVSDPFNRAAFWQLITPMYEEMLQIPEHKDIVTTLNILDVLYYKMGEYKKALQFSERALAIHPDVATSLDNLAGLYESMGNYKQALQLSER--------ALEIYEKVLGPQHRDVAITLDNLAGLYESMGEYEKALIFYQRTIEIHSNFATSLDNLAVLYRQMGEYEKALQLSQRALELGPQHPDIATTLNNI---------ALLYDSMGDYQKTLPLYQRALEINEKQYLGIATTLNNLAGFYRRVGDYEKALSLSQRSLEIHPDVARTLNSLALIYENIGDYEKALAFYQRSLDIHPDVGRTLNNLARLYEIMGDHEKALTLYQRTIEIKEK--------------------PQHPDVATILNNLAGLHYRIGEKKALPLYQRALDIVEKKLGQ--NQPNSVVIKNNYNRLLSKMSENEKK.......................... 914
43 -26.900[S] COG4700 Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats  ali follow..  11  60.....................................................................................................................................................LMRLQDKLNPERHLRKLTEELAIAET-NQNHYALANELARLGRYHEAVPHYQQALSGIFAHEA-----------AMMLSLAQAQFAIQEFAACQQTLEDVMRYNPDFQS--ADGHLLFARTLAAQEKYADAESEFEVLISYYPG-PQARIYYAEMLAKMSRLREANEQYVAVVDTAKRSRPHYRKHHREWIKTANERLKQSVVQ........................................................................................................................... 248
44 -25.900[O] KOG3696 Aspartyl beta-hydroxylase  ali follow..  188MATDVDDRFETLEPEVSHEETEHSYHVEETVSQDCNQDMEEMMSEQENPDSSEPVVEDERLHHDTDDVTYQVYEEQAVYEPLENEGIEITEVTAPPEDNPVEDSQVIVEEVSIFPVEEQQE----------------VPPETNRKTDDPEQKAKVKKKKPKLLNKFDKTIKAE-------LDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQC-----EDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFHLG....................................................................................................... 532
45 -25.500[S] COG1747 Uncharacterized N-terminal domain of the transcription elongation factor GreA  ali follow..  2............................................DTRDLTAYSAEKFKE--LDRIIAEAKRQSILDVLKGICDEHLAHSKNSIIALYISGIISLSKQLLDDSVTLLTIFGDNHKNQIVEHLCTRVLEYGESKLALRAL--GECYKTSGNEQLYDVWERLVRIDYEEAEITRVLADKYEQEGNKEKATEFYKKALYR--------------------------FIARRQNAAIKEVWTKLVALIPDD----VEFFYREQKKISEKLGEGRGSVLMQDV--------------YVYYKENEDWTTCINILKHILEHDEKDVWARKEIIENFRCKYRGHSQLEEYLKISNISQSWRNV--------------------------------------FEAINDFEKHISFDEGS........................................................ 293
46 -25.200[O] COG3914 Predicted O-linked N-acetylglucosamine transferase, SPINDLY family  ali follow..  11  3.............................QDVMTANHVSPSNDAAAPSALDLARNQRLSLDLLSVSEALNAAGQQAAAAELYKTWVAFNDNNPT-----------------------------------------------IHLAYFNYAVMLNQLGDRAGAVQAFRACLKANPEFAPGHINLGRALEDAGLIGHAVEQWSHYAEVTKNVDAETI-----HRHMTLQNMGRVLEGAGKLEEAETALLQAFELRPEL----PEAGQHWASLRQRQCKWPVLAPSNHISPRKMLDAMSSLTLSCYADDPMFQLAKAYRLSKTLIGARPDLSRFPRRSPKQKSGTGQRLR-VGYLSSDLRDHAVGCEVLELHDKDSLEVFAYYCGNVRGTDSTQERIKAAVHCWRDIHGVDDATAASQIIAD......................................................... 340
47 -24.900[R] COG4976 Predicted methyltransferase (contains TPR repeat)  ali follow..  11  2...........TFNQLSSGDLIADRRADYAKMLAEAGDAPGAAELMAQALELAPDWAAG--WFRLADYEEKSGRIEAAVDALRNTLRLNPEDIFGASLKLALLGATETPEQPPSVYVERLFDDYAERFDH-------------ALVEKLGYSVPEKLAAVIGRVNGGGRFRHVTDLGCGTGLFGERIRDRADFLEGFDLSANMLAKAEA------------------KGVYDRLAQADLSLAPEDSGVFGALEQRRADLVSA-----ADVLMYLGNLEGVFVIADRLLA---SVEDACGADGFVLRPSLRYAHPEASIASLCK......................................................................................................................................................... 279
48 -23.900[A] KOG2047 mRNA splicing factor  ali follow..  368.....RRPALANSVLLRQNPHNVEQWHRRVK--IFEGNAAKQILTYTEAVRTVDPGKPHTLWVAFAKLYENHKDLVNTRVIFDKAVQVNYHLASVWCEWAEMELRHKNFKGALELMRRATAVPTVEVAADGNEPVQMKLHRSLRLWSFYVDLEESLGTLESTRAVYEKILDLRIATPQIIMNYAFLLEENKYFEDAFKVYERGVKIFKY--------HVKDIWVTYLTKFVKRYGKTKLERARELFEHAVSMAPSDAV--RTLYLQYAKLEEDYGLAKRAMKVYEEATKKVPEGQKMYEIYISRAAEIFGVPRTREIYEQAIESGLPHKDVKIKFAELERSLGEIDRARALYKYSSQFADPRSD-----------------------PEFWNKWHEFEVQHGNEDTYRELRIKRSVSASYSQTHFILPENMMQKDKLLDVEDAKGELKRAGLPEDEMAAL................ 806
49 -23.700[O] KOG0543 FKBP-type peptidyl-prolyl cis-trans isomerase  ali follow..  20  235.........................................................................................................................................................................................................................EKLEQNTVVKEQGSVYFKEGKYKQALLQSQKAQAP-------PLASHLDLAMCQLKLQAFSAAIESCNKALELDSNNEKGPFRRGEAHLAVNDFELAWADFQKVLQLYPNNKAARAQLAVCQQRIHRQLARKKFYAKMFERLAEEENKAKAEACSGDHPTDTEMKAEWKSNT....................................................................................... 399
50 -23.100[DO] KOG4322 Anaphase-promoting complex (APC), subunit 5  ali follow..  16  234.....ASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSFDRLILTGAESKSNYAALNLAALHCRFGHYQQAELALQEAIRISNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNDSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYSETVLNLAFAQLILGIPEQALSLLHMAIEP--DKGRAMFLVAKCQVASAASYDQ----------PKKAEALEAANLNEAKNYF-AKVDCKERIRDVVYFQARLYHTLGKTQERNRCMLFRQLHQELPS...................................................... 746
51 -21.300[ODR] KOG4151 Myosin assembly protein/sexual cycle protein and related proteins  ali follow..  30  1.......................................................................................................................................................................................................................MVARVQTAEEIRDEGNAAVKDQDYIKADELYTEALQLTTDEKALRPVLYRNRAMARLKRDDFEGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKEALRLSPNDKGIVEVLQRLVKANNDKIKQ................................................................................................................................ 134
52 -21.200[R] COG4105 DNA uptake lipoprotein  ali follow..  14  46.........................................................................................................................................DQTEPADVLYNQGLANLNAGRLDEASKKFDAVDRQHPYSRKSMVMGAFADYRKGSYDEAISSAKRYLALYPSTDDAPYAQYII-GLSYYRQIKDVTQDQKEARQTLQTMQDLVTRWPTSEDQLAGKEMQIGRYYLERREYIAAVKRFRTVVENYSNTREALARLTESYYAMGLTSEAQTAAAVLGTNYPDSKDSYKLLQSNGLSPRENAGSWISK............................................................................................................................ 281
53 -21.100[R] COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion  ali follow..  11  2....................KKTDTLPATLSALIQEYSIAEGIQMAEQQVRENPAKALC--RHSLFQLLCVAGDWSRALHQLQLCARMEANYTQEARLYREL---------------------------------------------------VRCEMFRHTVFQGEQRPGFLLPQPVWVESLLAALACHDDTGEVDKHRNTALEAITDTGGQWNAFDWASDSDSRLGPVLELVTGGVY-----PFSQIRSLESPQPTRLTDLLWKPVNITLVNGDTHGAWESASDALRLDGPGETTVRALGQKVWLTSHGDISLLDMAH-CTFHAQENDG................................................................................................................................................. 273
54 -20.800[U] KOG1586 Protein required for fusion of vesicles in vesicular transport, alpha-SNAP  ali follow..  15  4.SGKEAEAMALLAEAERKVKNSQSFF---SGLFGGSSKIEEACEIYARA----------------ANMFKMAKNWSAAGNAFCQAAQL-------HLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIE------------------IYTDMGRFTIAAKHHISIAEI-------------YETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKV------AGYAALLEQYQKAIDIYEQVGTNDTPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDS-LLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKK........................................................................................................................................... 285
55 -19.200[M] KOG3364 Membrane protein involved in organellar division  ali follow..  4............................................................................................................................................................................................................................VDFWPTLKDAYEPLYPQQLEILRQQVVSEGGPTAT-----IQSRFNYAWGLIKSTDERLGVKILTDIYKEAESRRECLYYLTIGCYKLGEYSMAKRYVDTLFEHERNNKQVGALKSMVEDKIQK.................................................................................................................................... 126
56 -16.800[R] KOG0376 Serine-threonine phosphatase 2A, catalytic subunit  ali follow..  17  3....................KEALELKNEANKFLKEGHIVQAIDLYTKAIELDSTN--AILYSNRSLAHLKSEDYGLAINDASKAIECDPEYAKAYFRRATAHIAIFQPKEAVGDFRKALALAPSD--PAARKKLRECEQLVKRIRFQEAIHNTEPPSPLANINIEDMDIPSDYDGVIL-----EKQITKEFVEDMKERFCQGKKLPLKFRDLKELLEKTPSLIDIPVKGDETLVIGQYFDLLNIFKLHGPPSPTNKYLFNGDFVDRG---------SWSTEVAFTLYAYKLLYPDVFINRGNMNKVYGFEGECRSKYNERT-LFSDDNVTLDQLRNIDRFSKKQPGQSGLMMEMLWTDPQPAPRGPSKRGVGLQFGPDVSKRFCEAIRSHEVRDQGYEVEHDGYCITVFSA-----PNYCDSTGNLG................................................ 436
57 -16.500[T] KOG1309 Suppressor of G2 allele of skp1  ali follow..  2....................PVEKDLKTAYKALYDEKEPLKALHLYDEILKGSPTN--LTALIFKAACLEKLATMENAKELLDKALMTAEGRGD--------------------------------------------RSKIGLVNFRYFVHFFNIKDYELAQSYFKKAKNLGYVDDTLPLWEDRLETKLNKKNKKQKDSTNKHTIKPVESIENRGDNNSSHSPISPLKIETAPQESPYQSTISLFTVNLPESKEQVNIYISPNDRRGSEFQYNAKLSHEVDPKAVSLKIFPKKLEITLSKID--LEEDILTESSRLSDEGKNSDSATRLLSAETASKERLSYPSSSKKKIDWSKLDIDEEADEEAGSADSFFQKLYAGADPDTKRAMKSFIESNGTALSTDWEDV----KGTVKTSP.......................................................... 386
58 -16.500[R] COG5091 Suppressor of G2 allele of skp1 and related proteins  ali follow..  2....................PVEKDLKTAYKALYDEKEPLKALHLYDEILKGSPTN--LTALIFKAACLEKLATMENAKELLDKALMTAEGRGD--------------------------------------------RSKIGLVNFRYFVHFFNIKDYELAQSYFKKAKNLGYVDDTLPLWEDRLETKLNKKNKKQKDSTNKHTIKPVESIENRGDNNSSHSPISPLKIETAPQESPYQSTISLFTVNLPESKEQVNIYISPNDRRGSEFQYNAKLSHEVDPKAVSLKIFPKKLEITLSKID--LEEDILTESSRLSDEGKNSDSATRLLSAETASKERLSYPSSSKKKIDWSKLDIDEEADEEAGSADSFFQKLYAGADPDTKRAMKSFIESNGTALSTDWEDV----KGTVKTSP.......................................................... 386
59 -16.500[R] KOG3807 Predicted membrane protein ST7 (tumor suppressor in humans)  ali follow..  11  215.ERNPPARIKAAYQALELNNDCATAYVLLAEE--EATTIVDAERLFKQALKAGETNVLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPTMLNIHENLLESLLELQAYPDVQAVLAKDDISLPKSAAICYTAALLKTRTVSEKFSPETASRRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLHILKRGDSEAIAYAFFHLQHWKRIEGALNLLQCTHHVSVYPKKELPLFITHQFPEIMGIFAKAV----------LGLWCPQPWASSGFEENTQDLKSEDLGLS........................................................................................................................................................................................... 542
60 -16.400[B] KOG2084 Predicted histone tail methylase containing SET domain  ali follow..  19  20..........................................................................................................................................................RRGFFNEFCVDVRDACGDK-GKLKSNAARVLSIFSDREVCDPVLGVLEHVQPQKDALFSAQRRAQADKLYLMSGSGDGEESRELLQQALMAANLAVMRAPDEGLTLALAYRSRASILIRLGEGEAALNDLKLAINFLKSSVDYYLKMAKAYAVMGEPARAEISLKIAEKMPGCDATHIALCRKELSSVKPKPKEATSEQVPQLAHGESAELVGASKVVRLVETKDK................................................................................................ 264
61 -15.600[MOT] KOG1550 Extracellular protein SEL-1 and related proteins  ali follow..  11  401.....................................LMEEAVDEIEAASSAGDPHAQSIMGFVYGIGMMREKSKSKSFLHHNFAA--AGGNMQSKMALAFTYLRQDMHDKAVQLYAELAETAVNSFLISKDSPVVEPTRIHSGTEENKGALRKSRGEEDEDFQILEYQAQ--KGNANAMYKIGLFYYF-RDHTKALHWFLKAVDVERNYTKALEWLTLAAKIGYLYVKGY--VDKKNYTKAREYFEKAVDNEDPSGHYNLGVLYLKGIGVNR--DVRQATKYFFVAAN--AGQPKAFYQLAKMFHTKKNLEMATSFYKLVAE--RGPWSSLSRWALEAYLKGDVGKALILYSRMAEMGYEVAQSNAAWMCMGVSGFCTDKERHERAHSLWWRASEAALLIGD------YYYGRGTERDFVRAAEKSQSNAQAMFNLGYMHEH-FDLHLAKRYYDESLQ................. 866
62 -15.500[O] KOG1150 Predicted molecular chaperone (DnaJ superfamily)  ali follow..  23  2.............................................................................................................................................................................................................................................................................................RGSRGGWAGEMAASGESGTSGGGGSTEEAFMTFYKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDK-DDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQ............................................................. 135
63 -14.700[O] COG5159 26S proteasome regulatory complex component  ali follow..  12  2....................SLPGSKLEEARRLVNEKQYNEAEQVYLSLLDKDSSQSSATSILELGQLYVTMGAKDKLREFIPHSTEYMMQFAKSKTV-KVLKTLIEKFEQVPDSLDD--------QIFVCEKSIEFAKREKRVFLKHSATLHYQKKQYKDSLALINDLLREKPSLVDVHLLESKVYHKLRNLAKSKASLTAARTAANSIYCPTQTVAELDLM-----SGILHCEDKDYKTAFSYFFESFESYHNLTTHNSYEKACQVLKYMLLDDVKNILNAKYTKETYQSRGIDAMKAVAEAYNSLLDFNTALKQYEKELMGDE----TRSHFNALYDTLLESN----------------CKIIEPFECVEISHISKIIGLDTQQVEVLDQGNGWLYVYETPNQDATYDSALEL............................................................ 415
64 -14.700[S] KOG4459 Membrane-associated proteoglycan Leprecan  ali follow..  25............ESEAGWGMVTPDLLFAEGTAAYARGDWPGVVLSMERALR-------------------SRAALRALRLRCRT--------------------------QCAADFPWELDPDWSPSPAQASGAAALRDLSFFGGLLRRAACLRRCLG-PPAAHSLSEEMELEFRKRSPYNYLQVAYFKINKLEKAVAAAHTFFVGNPEHMEMQQNLDETQPHMQEFRLGVRLYSEEQPQEAVPHLEAALQ--EYNADLFQAITDHYIQVLNCKQNCVTELASHSREKPFEDFLPSHYNYLQFAYYNIGNYTQAVECAKTYLLFFPNDEVMNQNLAYYAAMLGEEHTRSIGPRESAKEYRQRSLLEKELLF......................................................................................................... 377
65 -14.500[R] COG4783 Putative Zn-dependent protease, contains TPR repeats  ali follow..  12  188.......................................QQGIISFTQGNEQEADRIGIQVLQRSGFDPQAMPNFLQKLADQSRYVSKPPEMLLTHPLPDSRLSDARNRANQMKPHPTASSQDYLFAKMRILGMYGADENSLTPELLDQAVQLYQAKKYDEARNLLQPLLAQQPGNIWFLDLMTDIDLGQNKSAAAIARLQNAMVKQNDEPVLQLNL------------ANAYVQGRQPAAAIKLLHRYTFAYPND----PNGWDLLAQATATQGLRDQE-----------------LAARAESLALSGKLTQAIGLLSDASARVKLGSLEQARYDARIDQLRRLNERFRKYQKS......................................................................................................................... 486
66 -14.000[S] COG1729 Uncharacterized protein conserved in bacteria  ali follow..  19  229...............................................................................................................................................................AGKSNGTIVAALPSTNDPEELYRNSYQFILSGDYGTAEQGFRDHISRFPRDAKAADAH------------GESLLGQQKYRDAAEVFLAASKDYPKAKKA-PDMLLKLGVSLVGLKQHDVACATFSEVGKRYPDISSALKERVKQ............................................................................................................................................................................ 363
67 -13.700[O] KOG0713 Molecular chaperone (DnaJ superfamily)  ali follow..  54  2.............................................................................................................................................................................................................................................................................................................................................SAKKLEGSSAPANRRDPYEVLCVSKDANDQEIKSAYRKLALKYHPDKNANNPDASELFKEVAFSYSILSDPEKRRHYDN................................................................ 80
68 -13.500[S] COG2912 Uncharacterized conserved protein  ali follow..  11  41ELAAIDMLVARLKSRIVEGTPAIQRLRVLNQFFYRELGFGPNANDYYDP----ENSYLNAVLQTRRGIPISLA----LLMEIGQQIGLPPNHFLVRMSIPAGEVVIDPLTGQPYLEKEGIEDPNSVPLGVFLQVAT-HREIVARMLRNLKAIYLQESRWQRLLAVQQRLVILLPESIEEVRDRGLAYANLECFRPALADLEAYVDARPDAADTPKLKERMPTLRAMSRN....................................................................................................................................................................................................................................................... 279
69 -13.300[O] KOG0719 Molecular chaperone (DnaJ superfamily)  ali follow..  43  28.........................................................................................................................................................................................................................................................................................................................................................MDIDPYSVLGVEKDASDELIRRAYRKKALQHHPDRIHDEEEARIEFDKVAIAYGVLSDKKRRKHYDK................................................................ 97
70 -13.200[S] COG3014 Uncharacterized protein conserved in bacteria  ali follow..  20....................IGYRMDLEHFNTLYYEESPKKAYEYSKQFTKKKKNA--LLWDLQNGLSALYARDYKTSLGVLDQAEQR---------------------------------------FDKTQSAFTRGAGYVGATMINDNVRAYGGNIYEGVLINYYKAID---------------YMLLNDSAKARVQFNRANERQRRAKEFYY---------------------EEVQKAIKEIDSSKKHNINMERSRAEVSEILNNTYSNLDKYEAYQG----------LNPAVSYLSGLFYALNGDKNKGLGYLNEAYGISQSPF................................................................................................................................................... 242
71 -13.200[S] COG1655 Uncharacterized protein conserved in bacteria  ali follow..  13  86.........................................................................................................................................................................................................................ELVEKNISLKWHSKKYPDIYDINIAIERFKLSLVSIEAHSSKKAMNCLKIAWMYRIQQNEDMEKVFLKNALEGGMNKFSLMYLIGELHRRLGDEDKALLWFGNVITNSLAPQKLKEMARNQKDLIRENEKKLSQTQDNDSNDDDNSEATTP............................................................................................................ 252
72 -12.900[OT] KOG1464 COP9 signalosome, subunit CSN2  ali follow..  13  44.EDDPKAALSSFQKVLELEGEKGKALKQMIKINFKLTNFPEMMNRYKQLLSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALKDAFKTNTKLGKLYLEREEYGKLQKILRQLH----QSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAMGVIRECGGKMHLREGEFEKAHTDFFEAFKINPFDSQEAKPYKNDPEILAMTNLVSAYQNNDEFEKILKTNHSNIMDDPFIREHIEELLRNTQVLIKLIKPYTRIIPFISKELNIDVADVESLLVQ---CILDNTIHGRIDQVNQLLELDHQKRG-----GARYTALDKWTNQLNSLNQAVVSKLA................................................................................................................... 443
73 -12.800[O] KOG0724 Zuotin and related molecular chaperones (DnaJ superfamily), contains DNA-binding domains  ali follow..  27  9...........................................................................................................................................................................................................................................QGGYSLGVRCSSYK----------LFIMPSRRSESAIRLITYSEELVDGKPFFAFGHAFHSAALKLHGCAEEPTDDEGGDKKVGD--DKEKEYVPSFNSYANKGKKKSGTQQQDHYALLGLSNLATEDQIRKSYREAALKHHPDK-AKKDEIESRFKAIQEAYEVLMDPTRRRIFDS................................................................ 195
74 -12.800[A] KOG1258 mRNA processing protein  ali follow..  51.KQAINTLRSVYDRFLGKYPLLFGYWKKYADFEFFVAGAEASEHIYERGIAGIPHSVDLTNYCA---KMETNGDANEVRELFMQGANLDFLSHPFWDKYLEFEERQERPDNVFQLLERLQYARYFERFVQVSQSQPIQQLLPPDVLASIRADVTREPA-SEIKRPYFHVKELDEAQLVNWRKYLDFEEVEGDFQRICHLYERCLITCALYDEF---FRYARWMSA---------QPDHLNDVSIIYERASCIFASISR--PGIRVQYALFEESQGNIASAKAIYQSILTQLPGNLEAVLGWVGLERRNAPLTNAHAVLRSIINEGKCNTGITEVLKLVWKIEGDIELARNMFLQNAPALLDCRHFWISFLRFELEQNSKNYTEHHARVSNVMEMIRNKTRLPPRTIMDLTKLYMEYLCHQSN...................................................... 524
75 -12.500[A] COG5107 Pre-mRNA 3`-end processing (cleavage and polyadenylation) factor  ali follow..  21.SDNIHGDELRLRERIKDNPTNILSYFQLIQYLETQESYAKVREVYEQFHNTFPFYSP--AWTLQLKGELARDEFETVEKILAQCLSGKLENNDLSLWSTYLDYIRRKNNLITG--GQEARAVIVKAFQLVMQKCAIFEPKSSSFWNEPFNKWEEQQRIDMLREFYKKMLCVPFDNLEKMWNR---YTQWEQEINSLTARKFIGELSAEYMKARSLYQEWLNVTNGLKRASPINLSDSNIQQLQIWLNWIKWERENKLMRISYVYKQGIQYMIISENSDRQNILYTALLANPDSPSLTFKLSECYELDNDSESVSNCFDKCTQTREKLTFVFCVYMNTMKRISGLSAARTVFGKCRKLKRILTDVYVENAKTAFKVLELGLKYFQNDGVYINKYLDFLIFLNKDSQIKTFETSVE............................................................. 511

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.