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Query: [C] KOG0758 Mitochondrial carnitine-acylcarnitine carrier protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTTTENVSTERKANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMCFAGYALGKRLQQRGEDAKLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDVAKSKSETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPEGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAACFFGIELANKFFNIVAPNFLast
1 -102.000[C] KOG0758 Mitochondrial carnitine-acylcarnitine carrier protein  ali  100  1MTTTENVSTERKANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMCFAGYALGKRLQQRGEDAKLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDVAKSKSETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPEGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAACFFGIELANKFFNIVAPNF 306
2 -87.500[C] KOG0762 Mitochondrial carrier protein  ali follow..  37  1............MSALLDLFAGSLGGAAGVLAGHPLDTVKVRLQTQS----GPTPQYRGTFHCFKLIVQKEGFRGLYKGMSSPLLSLSAINAIVFGVHGGTCRQM----EDPDSITSHFVGGCAAGMAQSVIAAPTERIKLLLQIQDDK-AHTKFNGPIDATKQLLRTHGLKSLTRGFLATVARDAPAFGVYFASYEWMARSMCKDGETSTLSSGQLLFAGGTAGMLSWLFNYQTDIIKSRFQADNS---YKSYMHCIKQTYLERGYRGFFVGLNSALIRAFPSNAATFFTVEWTYRILLDFNVI. 281
3 -86.000[C] KOG0763 Mitochondrial ornithine transporter  ali follow..  29  1MHGGGTGNNINFVEGLIDFLAGSLGGAAQVYVSQPLDTVKVKLQTFPE-------AYRGMLDCFLSTYRKDGLRGLYAGSVPAVFANVAENSVLFAAYGGCQKFVAFETAGDLTTVQNACAGSLAACFSTLTLCPTELIKCKLQALREPAHPQDIRTPWTLTRYIWRTEGIRGFYRGLSSTFLREMPGYFFFFGSYEGTRELLRRDQSKDDIGPLRTMIAGAIGGVCLWTSTFPADVIKSRIQVKN---LNESMFAVGADIVRREGVLALYRGLLPSVLRTIPATATLFVVYEYTKRALSA..... 303
4 -86.000[C] KOG0754 Mitochondrial oxodicarboxylate carrier protein  ali follow..  21  1..MATRSEETVRSLAHWQFLAGGLSGFIEIICFHPLDVVKTRMQIQGAHPFGGEVVYTCPLDAIVKIYRYEGLSSLWKGIVPPICVETPKRGGKFLMYESLKPYFQF-GAPQPTPLTHAMSGSMAAILESFLVNPFEVVKITQQAHRG-----KRLKTLSVVKYIIKHDGIKGLYRGITALVARNAVFHFGFFGFYNALKDIVPS-PEDKTYNILRKVIIAGLASSLACVMSVTLDMAKCRIQGPQPEVKYQWTISTIKSTFKEEGFRSLFKGLGAMILRVGPGGAMLLVTYEYLFEFLKSQN... 299
5 -85.900[C] KOG0756 Mitochondrial tricarboxylate/dicarboxylate carrier proteins  ali follow..  23  1..MATRTESKKQIPPYMKAVSGSLGGVVEACCLQPIDVIKTRLQLDRVG------AYKGIAHCGSKVVRTEGVRALWKGLTPFATHLTLKYTLRMGSNAMFQTAFKDSETGKVSNRGRFLSGFGAGVLEALIVTPFEVVKIRLQQQKGSPELFKYKGPIHCARTIVREESILGLWSGAAPTVMRNGTNQAVMFTAKNAFDILLWNKGDGKILQPWQSMISGFLAGTAGPFCTGPFDVVKTRLMAQSRDSRYKGMVHAIRTIYAEEGLVALWRGLLPRLMRIPPGQAIMWAVADQVTGLYEMRYLR. 305
6 -84.900[C] KOG0750 Mitochondrial solute carrier protein  ali follow..  25  1...................MNGGLAGIIGVSCVFPIDLVKTRLQNQTVGADG-KLQYSGIADCAKQTWRSGGARGMYSGSGVNILLITPEKAIKLVANDFFRHKLAKEGEKQLSVGRGMLAGGLAGMFQISVTTPMELLKIQMQDQGRTKPGQQKLSATQLTMKLVKENGIAALYKGLSSTLARDVTFSVIYFPLFAYLDSLAPRKDGSGDAVFYGSFLAGLTSGAASSFCVTPLDVIKTRMQTINKGAVYKNIPDAFVTIFKNEGPKALFKGAACRMMVMAPLFGIAQTVYYIGVAEK....... 290
7 -82.700[C] KOG0755 Mitochondrial oxaloacetate carrier protein  ali follow..  20  2..............ATSDFVLGGLASVGATFFTNPIEVIKTRIQLQGEARGTYVEPYKGIVNAFITVAKNDGITGLQKGLAPALYFQFIINSFRLSIYSEAMERRMHNRKGEVSYGMGLLWGAIGGVVGCYFSSPFFLIKTQLQSQAAKGYQHAHTSMTDALRQIYSRNGVRGLWRGSVAALPRAALGSGAQIATFGKTKALLVQYDLVTQ-PTLNSFSAGLIAGSIMSVAITPPDVITTRLYNQGVDALYRGWLDCFVKILRSEGVYGMYKGFWANYLRIAPHSTLVLLFFDELVAVRTKYSNQ. 303
8 -82.200[C] KOG0766 Predicted mitochondrial carrier protein  ali follow..  19  2..SEIKKTEKLGVKSSKHLAAGALGGFISSTTLQPLDLLKTRCQQSQRD--------SLPKMVRRIILHEGGVFSLWKGTLPSILRSTTGSSCYFYFLNWLRHFAPQSKNIASSHIQNLWMGGFARAAVGFAFMPVTVIKVRYESNLY-----SYTTIYSSIRDIWKKEGISGFFRGFGVTALRDAPHAGLYVYFYELSKQNLHKVQGTVPHRNIVNVMSGLISGATATAITNPFDMLKTRVQLEPH--IYKNFLHSAKLVYANEGFRGFLDGFFLRVLRKSISSTITWSVYEWALHRK....... 293
9 -81.200[C] KOG0749 Mitochondrial ADP/ATP carrier proteins  ali follow..  18  5.GGGGGHGKGDLKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQEVSKQAADQRYKGIVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHRHFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDFLP---NPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSSEMVYKNTAHCWLVIAKQEGIGAFFKGALSNIIRGTGG-ALVLALYDEMKKYF....... 307
10 -81.100[C] KOG0752 Mitochondrial solute carrier protein  ali follow..  23  12MSGTELDEPGKLKRAVIDASAGGVAGAISRMVTSPLDVIKIRFQVQLEPTAQLKPKYNGLFRTTKDIFREEGLSGFWRGNVPALLMVVPYTSIQFAVLHKVKSFAKAENHAQLSPYLSYISGALAGCAATVGSYPFDLLRTVLASQ---GEPKVYPNMRSAFLSIVQTRGIKGLYAGLSPTLIEIIPYAGLQFGTYDTFKRWSSSTNPSDSLSSFQLFLCGLASGTVSKLVCHPLDVVKKRFQLNA----YKNMFDGLGQILRSEGWHGLYKGIVPSTIKAAPAGAVTFVAYELASDWFEA..... 324
11 -80.900[C] KOG0753 Mitochondrial fatty acid anion carrier protein/Uncoupling protein  ali follow..  24  2..........GEVKDWRPFVYGGVASITAEFGTFPIDTTKTRLQIQGQDQSFSQLRYRGMTDAFVKISREEGLRALYSGIWPAVLRQATYGTIKFGTYYTLKKLANENEDGSERVWSNILCAAAAGAISSAIANPTDVLKVRMQVH----GKGQHKGLLGCFGEIYKYEGVRGLWRGVGPTAQRAVVIASVELPVYDFCKLQLMNAFGD---HVGNHFISSFIASLGSAIASTPIDVIRTRLMNQATPKLYSGSLDCAVQTIRNEGLPALYKGFIPTWVRMGPWNIIFFITYEQLKKY........ 303
12 -79.300[C] KOG0757 Mitochondrial carrier protein - Rim2p/Mrs12p  ali follow..  22  2.....ATGGQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPN-SNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGS-KQMNTLQCARYVYQTEGIRGFYRGLTASYAG-ISETIICFAIYESLKKYLKEATEKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREE--GTKYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLLEDRT... 320
13 -78.800[C] KOG0759 Mitochondrial oxoglutarate/malate carrier proteins  ali follow..  24  2.......SNEGGVPNVVKFAFGGTAGMGATLVVQPLDLVKNRMQLSGT---TGKKEYRSSMHALTSIMKNEGVFAVYNGLSAGLLRQATYTTTRLGTYAFLLERFTE-KDKPLSFGMKAVLGMTAGGIGSFVGTPAEIALIRMTGDGRVEQRRNYTGVVNALTRITKEEGVLTLWRGCTPTVLRAMVVNAAQLATYSQAKQALLASGKVQD-GIFCHFLASMISGLATTIASMPVDIAKTRIQSMDGKPEYKNAFDVWGKVIKNEGIFALWKGFTPYYMRLGPHTVLTFIILEQMNAAYFQ..... 295
14 -77.800[C] KOG0764 Mitochondrial FAD carrier protein  ali follow..  23  1...............................LLSPIRLFFLSVQIQEMSAAAGAAAGSLIVGSLEQIFKREGMRGLYRGLSPTVMALLSNWAIYFTMYDQLKSFLCSSGDHKLSVGANVLAASGAGAATTIATNPLWVVKTRLQTQGMRVGIVPYKSTFSALRRIAYEEGIRGLYSGLVPALAG-ISHVAIQFPTYEMIKVYLAKKKSVDNLNARDVAVASSIAKIFASTLTYPHEVVRARLQEQGHHSRYSGVRDCIKKVFEKDGFPGFYRGCATNLLRTTPAAVITFTSFEMVHRFLVTHIPS. 306
15 -77.200[C] KOG0770 Predicted mitochondrial carrier protein  ali follow..  26  39LHKKRGDSDEDLSPIWHCVVSGGIGGKIGDSAMHSLDTVKTRQQGAPNVK-----KYRNMISAYRTIWLEEGVRGLYGGYMAAMLGSFPSAAIFFGTYEYTKRTMIE-DWQINDTITHLSAGFLGDFISSFVYVPSEVLKTRLQLQGRFNSGYNYSNLRNAIKTVIKEEGFRSLFFGYKATLARDLPFSALQFAFYEKFRQLAQKDGRDGELSIPNEILTGACAGGLAGIITTPMDVVKTRVQTQQPPSLSNSISLSLRTVYQSEGVLGFFSGVGPRFVWTSVQSSIMLLLYQMTLRGLSNAFPT. 367
16 -76.600[C] KOG0768 Mitochondrial carrier protein PET8  ali follow..  25  113.............RAIIGAGAGGLAGAFTYVTLLPLDAIKTKLQTK-----GASQVYSNTFDAIVKTFQAKGILGFYSGVSAVIVGSTFSSAVYFGTCEFGKSLLSK-FPDFPTVLIPPTAGAMGNIISSAIMVPKELITQRMQAG-------ASGRSYQVLLKILEKDGILGLYAGYSATLLRNLPAGVLSYSSFEYLKAAVLEKTKQSHLEPLQSVCCGALAGAISASITTPLDVVKTRLMTQIHGAMYTGVAGTVKQILTEEGWVGFTRGMGPRVVHSACFSAIGYFAFETARLTILNEYLK. 399
17 -76.300[R] KOG1519 Predicted mitochondrial carrier protein  ali follow..  21  27.SKQDISPHITNVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQL-----------YGIKTRDAVLQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRK-HVRAPEFATHGVAAVLAGTAEAIF-TPLERVQTLLQNH----KHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHL-PTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQ-IGGEFQSFPKVFQKIWRDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFI....... 307
18 -75.700[C] KOG0760 Mitochondrial carrier protein MRS3/4  ali follow..  22  7.......ESLPTTSVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSLSPPT-----KNMNIVSTLRTMITREGLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAK--FTSVRNLNYVISGAVATLIHDAISSPTDVIKQRMQMYNS-----PYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQNKM---NLERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQETG-LTRGMIEASRKIYHMAGPLGFFRGTTARVLYSMPATAICWSTYEFFKFYLCGLDAD. 288
19 -75.200[C] KOG0761 Mitochondrial carrier protein CGI-69  ali follow..  23  32.TLILSADPRYRIKPMQQVVSALVGGLITTFVVTPLEVVKTRVQTQPGRDPQNLRPLRGAMDAFVKIVCTSGFSGLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHVSTASLPYYVPMASGICSRTIVVTAITPIEMVRIKMQSE-----YMTYAELWRVLRSLIRQHGILGLWRGWPPTVMRDAPFSGTYWAVYEAIKRAF----SVTEPTFLFSFLTGAISGAVATFVTMPFDLITTHTQIEAVANSRPSVLSRMRQIYRLQGVRGLYVGVMPRMLRVVPACAIMISTFEYSKSFFFHYNLD. 431
20 -74.100[C] KOG0769 Predicted mitochondrial carrier protein  ali follow..  19  1............MLTLESALTGAVASAMANIAVYPLDLSKTIIQSQVSPSSSENRRYKNVVDCMINIFKEKGILGLYQGMTVTTVATFVQNFVYFFWYTFIRKSYNRDGPITPSTIEELVLGVAAASISQLFTSPMAVVATRQQTVHSA----ESAKFTNVIKDIYRENDITAFWKGLRTGLALTINP-SITYASFQRLKEVFDHSNDAGSLSAVQNFILGVLSKMISTLVTQPLIVAKAMLQSA--GSKFTTFQEALLYLYKNEGLKSLWKGVLPQLTKGVIVQGLLFAFRGELTKSLKRL.... 308
21 -73.000[C] KOG0767 Mitochondrial phosphate carrier protein  ali follow..  23  51VEEQYSCDYGSGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQ-------KYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQ-----PGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEK--------GSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPP. 346
22 -71.900[F] KOG0036 Predicted mitochondrial carrier protein  ali follow..  22  172VPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRS-----NNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGS-DQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALR----KTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQAEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQS... 468
23 -71.300[C] KOG0751 Mitochondrial aspartate/glutamate carrier protein Aralar/Citrin (contains EF-hand Ca2+-binding domains)  ali follow..  27  350HHKDDRGVGTAFLESAYRFLLGSVAGACGATAVYPIDLVKTRMQNQRTSGSVGEVMYKNSLDCFKKVVKFEGLLGLYRGLLPQIVGVAPEKAIKLTMNDYMRDKFTK--DGKIPLYGEIIAGGTGGMCQVVFTNPLEIVKIRLQTA----GEVQQAGKKIGVFTVLKELGFLGLYKGSRACFLRDIPFSAIYFPAYAHAKLASA--DEDGMNSPGTLFASAFIAGVPAAGLVTPADVIKTRLQVAARATTYNGVIDCARKLIKEEGPMSLWKGTAARVCRSSPQFAVTLLTYEVLQRLFYVDFA.. 648
24 -68.200[R] KOG2745 Mitochondrial carrier protein  ali follow..  14  1MAGFPE--HARAEDTEVNVWIRFGLRLGVSAALHPFEYSKTLIQLGYEPIAKPIMKLPNIFQYAGHIRRIDGFYGCYRGLAPKLVGSLVAMVVSDRVADQLGLEQPEENKDDVQFKKSLKRDIVLMVSGVVASHPFHVISLRMMAQ-FVGRETLYTSIVGSVAEIWKSEGIAGFFAGLVPKLLGDLACLVLSSSTIYILNKYIIKDKLGR-------QYNSGFTQFAVSSLLYPLQVVSTCSAVSGSRPAYRNWVDCWNDLQVRGELKRGSSLFWRSQSISSPVIATSFAPLPKLARY........ 315
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.