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Query: [F] KOG1096 Adenosine monophosphate deaminase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSATVCKMTSARLVPTLVLFYFEFITELSTNQLKAVGRYLRLKRNPILFNGTQETFSKSLFNFPHFPYRQNVEKCVGRILKNAEDTNGVHFFNPAADNSDEETTAASPSSDVARPNPLDSAREYGMNNLPPDITEAQIETVDSELFDSGPFKKNFAFGNADHSTASPFEISTTPIEVNESRAHKTIEISNREKGAKSRRWSCLARLESQNDGCLSPSSLKSVLDEIQTEPRCKSPQHIDLHTFRDAVDVNYQRMAITGEELSGVPLEDLKTASGHLIEALHLRSKYMERIGNQFPSTTRNFLSGHYPANLPKHRVKNTETTVQTSFNPPDPPKDHWGKNDPLPKYEKIYHLRRNRGVTEICNDDGSIDQQFKNVNVTKEEFLNDTEKLTAMIVDGPLKSFCFRRLSYLENKFQLHVLLNELRELHEQKGVSHRDFYNIRKVDTHIHAASSMNQKHLLRFIKKKIKTEADTVVLNNNGTKVTMKEVFKKMGIDAYDLSVDMLDVHADRNTFHRFDKFNTKYNPVGESTLREIFIKTDNYVGGKYFADLLKEVLSDLEDSKYQHAEPRLSIYGRSKNEWDNLAKWALTHDVWSPNARWLVQIPRLYDVYRAKNMVKNFDDMLDNLFTPLFEVTNDPSSHPELHLFLQQISGIDSVDDESKHEFVNFDRSTPCPPEYTDLENPPYNYYLFYMYRNICALNAFRRARGLNTFALRPHCGEAGHVSHLLTGYLTSESIAHGILLRKVPVLQYLYYLTQIGIAMSPLSNNSLFISYQRNPLPEYLQKGLNVSLSTDDPLQFHYTKEALMEEFSIAAQVWKLSSCDMCELARNSVMQSGFEDKVKIHWLGPNYKEEGVLGNDIHRTNVPDIRVSFRHEALVDELYNLFRVQNTLKQLast
1 -297.000[F] KOG1096 Adenosine monophosphate deaminase  ali  100  1MSATVCKMTSARLVPTLVLFYFEFITELSTNQLKAVGRYLRLKRNPILFNGTQETFSKSLFNFPHFPYRQNVEKCVGRILKNAEDTNGVHFFNPAADNSDEETTAASPSSDVARPNPLDSAREYGMNNLPPDITEAQIETVDSELFDSGPFKKNFAFGNADHSTASPFEISTTPIEVNESRAHKTIEISNREKGAKSRRWSCLARLESQNDGCLSPSSLKSVLDEIQTEPRCKSPQHIDLHTFRDAVDVNYQRMAITGEELSGVPLEDLKTASGHLIEALHLRSKYMERIGNQFPSTTRNFLSGHYPANLPKHRVKNTETTVQTSFNPPDPPKDHWGKNDPLPKYEKIYHLRRNRGVTEICNDDGSIDQQFKNVNVTKEEFLNDTEKLTAMIVDGPLKSFCFRRLSYLENKFQLHVLLNELRELHEQKGVSHRDFYNIRKVDTHIHAASSMNQKHLLRFIKKKIKTEADTVVLNNNGTKVTMKEVFKKMGIDAYDLSVDMLDVHADRNTFHRFDKFNTKYNPVGESTLREIFIKTDNYVGGKYFADLLKEVLSDLEDSKYQHAEPRLSIYGRSKNEWDNLAKWALTHDVWSPNARWLVQIPRLYDVYRAKNMVKNFDDMLDNLFTPLFEVTNDPSSHPELHLFLQQISGIDSVDDESKHEFVNFDRSTPCPPEYTDLENPPYNYYLFYMYRNICALNAFRRARGLNTFALRPHCGEAGHVSHLLTGYLTSESIAHGILLRKVPVLQYLYYLTQIGIAMSPLSNNSLFISYQRNPLPEYLQKGLNVSLSTDDPLQFHYTKEALMEEFSIAAQVWKLSSCDMCELARNSVMQSGFEDKVKIHWLGPNYKEEGVLGNDIHRTNVPDIRVSFRHEALVDELYNLFRVQNTLKQ 889
2 -60.700[F] KOG1097 Adenine deaminase/adenosine deaminase  ali follow..  12  58......................................................................................................................................................................................................................................................................................................................................................................IFNSFERYSGVGNDIQLTLPER---AANELIMCEKKREYEKGIMDPSKFAPGH-----HIFQVLTKVKKSPLFQILRRMPKGAALKAHDTSMCSSRVVIEITYRD-----NLWVCTTQNGCRVEEFRFAKDKPKDVSFENGEWQPMEKLRELRGEENLRKTTNAHAWRHMMGIFGLLDGLLQYAPWGDYYYNALKEFYADGVQYLEVRSVLP----------------------------------QLYSLDGSRMPKRETVQIYKDTLERFKKEHPG-DSKLIYAPIRHVQPELVGEYIKECTELNKEFPSFVVGFDLVGQEDVG-------HPLSNFAAELLKLPDHIHFYFHAGQTNWYQNLLDAILGTKRIGHGYTITKHPVLMRLAKYLNIALEVCPVSNQVLGSDYRSHPAATLIAENVPMVIASGSPGFWRAA--PLSHDFYMAFLGIAADLKFLKRTAKNSIKYSSLKDEAKAEAMEKWKKQWDKWVENIVRQR............................. 530
3 -52.500[F] COG1816 Adenosine deaminase  ali follow..  14  1........................................................................................................................................................................................................................................................................................................................................................................................................................................MSNLPIYNFIRKLPK-CEHHVHLEGCLSPDLVFRLAKKNGITLPS-----------------------------------DDAAYTTPSTLLASYEHFGCLDDFLRYYYIAVSVLEASDFEALAYEYFSIAHSQGVHHAEVFFDPQTHTSR---------------------------------------------GISYDVVVSGFSAACERANRDFGMSTNLIMCFLRHLPSEAAHETFAEALKRNDFENGIVAGVGLDSSEVDFPPELFQEVYKLAAEKGIRRTGHAGEEGDPSYIRSGLLSLQRIDHGIRLVEDKELMKRVAEENIMLTMCPLSNLKLVNSIAELPVREFLEAGVPFSINCDDPAYFG---GYTLENYFAIQKHFNLTVKEWVFIANAAINGSWISGKRKEELLSSVQKCVKEYTAEIQQPKTLETAVEVQ.................... 366
4 -14.500[FQ] KOG3968 Atrazine chlorohydrolase/guanine deaminase  ali follow..  14  219...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SETLMGELGNIAKTRDLHIQSHISENRDEVEAVKNLLTNKTVAHGCYLSAEE--LNVFHERGASIAHCPNSNLSLSSGFL--NVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDG---------------EIGNFEVGKEFDAILINPK........... 403
5 -12.900[Q] COG1228 Imidazolonepropionase and related amidohydrolases  ali follow..  16  228...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TVEQSRTFLQKAKERGFGLKLHADEIDPLGGALAGELGAISADHLVGASDQG--IQKMAAAGTIACLLPGTTFYLGKD----RARDMIDQGLAVTISTDFNP--SSPTENLQLIMSIAALRLKMTPEEWHAVTVNGAHAGQLAVGRAADVVVWDAKNYYYVPYHYGVNHVHSVEVVYERRRAFEGLS........... 423
6 -12.100[K] COG5641 GATA Zn-finger-containing transcription factor  ali follow..  7  129PVCKNCLTSTTPL--MLCLFL---LH--GKPRPISLKT-IKSRRKSNTNHAHNLDNFRNQTLIAE-KANRVTSEDKKKKSSQLLMGTSSTAKISKKPKTESKERSDSHLSATKLEVLMSGDCSRPNLKPKLPKQDTAIYQEKLLTFPSYTDVKEYSNSAHQSAFIKERSQFNAASFPLNASHSVTSKTGADSPQLPHLSMLLGSLSSTSISNNGSEIVSNCNNGIASTAATLAPTSSRTTDSNPSEVPNQIRSTMSSPDIISAKRNDPAPLSFHMASINDMLETRDRAISNVKTETTPPHFIPFLQSSKAPCISKANSQSISNSVSSSDVSGRKFENHPAKDLGDQLSTKLHKEEEIIKLKTRINEL------------ELVTDLYR---------------RHINELDGKCRLEERLQRTVKQEGNKG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 550
7 -11.600[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  7  1MAETLSRLSDLRVID---L---D-VRKRNVDSNKSV--LME-RLKKAIEDEGGNPDEIEITSEGNKKTSKRSSKGRKPEEEGVEDNGLEENSGDGQEDVETSLENLQDIDIMDISVLDEAEIDNGSVADCVEDDDADNLQESLSDSRELVEGEMKELPEQLQEHAIEDKETINNLDTSSSDFTILQEIEEPSLEPENEKILDILGETCKSEPVKEESSELEQPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSPEDDSDTKRLSKE---------EKGRSSCGRNFWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARC---FVTMSTAEEATKCINHLHKT.......................................................................................................................................................................................................................................................................................................................................................................................................................................... 470
8 -10.800[KA] KOG2868 Decapping enzyme complex component DCP1  ali follow..  8  9MNLAAIKKIDPYAKEIVAFYTFNFIYHRNAESIFINNRLLQSQPPFLLYRNERSRIGLLKSKDQGTNGQAQRHVSAPQQPKQDSSQPASIFNMLTKAQKDYNAQVSGGQPKTPSAENVTAGNVLKFFESAKQATAESLFHRVQPLSVDQLEKQQRAATPGEDLLPPAGRDNHESRLSPFQKMQQLNIQLLSDLKIGKSYATAQSPTVAPSSSALMANDDAGKCLRRLLAGDKPGPALMPPTMFDAPNNGNPEPQQPQQPQQPLLNSTQFVQAFTYLIQ--KLHKAYLNGCSNLLLDSSSTY............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 371
9 -10.500[S] KOG1181 FOG: Low-complexity  ali follow..  13  54MQPVV--LE--RL-PLL-----NYL-KR-VDQLLTINTLVSIKHEPEVHINDTGPPRGQAESDPE-PERNEEHPSFGDDIQAANDECQECQPETESDKISVAACDDIPSVSVKQEPEYDGYEKQTGVKQEPLKLKLKITKNHGKLNSSLIDDLDEAGQAFGRSSKKKKKRKHKEREKEASNETENCRTESQNQPAIKIKQEPVDYAPEATVMTTIPMTQFESSLNESERSEEVDEAMIQSQEDVKPNRMELDRMMQISNVTSGVDMAEEAMALERAEEACPEDSLHKVKSVKSTARKST.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 367
10 -10.000[U] KOG3709 PACS-1 cytosolic sorting protein  ali follow..  9  14LYATIFNVSINRIL-SIIVFCIQYPHKRKSNVLQ-IQRRKKFKNRLPGKGVGACAGKIFLSSCYSQAPEIVDDRDKQKKNVEDSEDETETDYDDVGDELNEMPSARSGRHKTSTDIETRTGRTKGKNKLFNMFRPEDGRRPVVKEMPWEDDDIDSPYDSGPEMFNDDASIRSNPFFDSKEKNDHLAAMYEVSDGEGDHGEGGWNSDGDNTKENVARHRLIQKDSIGSGHPDYSVQTPVRSAGIRVVSSSFDSHSMPHSSTLNSIKNDHGVHRGVSLSEQLC................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 400
11 -9.880[O] KOG4275 Predicted E3 ubiquitin ligase  ali follow..  8  31IASRRCKLSRTDLPKDL-----FYLQSKHISTEGCLEKLVGL-----VLTHVAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFFSNLSDNISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVSTREIPTYASAVNGGPQHVHVQQQATTTNGGSQSSSSPSTSTQSSNNRDASSSSQAHVAHQEARNEEQEDAQSKSDCECSDEEIMATFSERVSISLKTDTSGRRVNAAAEPSPVDLANVDNGPAGNTAPSPGCSKPGSSSSKADASSQ...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 311
12 -9.370[K] KOG0848 Transcription factor Caudal, contains HOX domain  ali follow..  12  188.........KYRVVYTLELFHYRYITRRKAEATLGLERQVKIRR-----------------------AKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVSG.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 294
13 -9.360[O] KOG0823 Predicted E3 ubiquitin ligase  ali follow..  11  114FDCNIC-LEKAE--PILTLFFYQLPLIYLNIKECPVAEVIPIYGNGDDCDGTKPKLEDCGISLPPRPNAKRVESVRQKIINRGNPFFPGHENEAIEHIRR-----IDSIGLQALAQGDEFGLTNIINNGGDNGGQQQQQQHHHHHHPPFGPLRLLPPYATFPGLLVDTSDIPAPFDDDAFDVDSFVDTTSLRRNRRRPSPAVRASYQRNRSNNASQTISFRLGSSASSAPREFAVPSSSIMTRSQTVNPTEVVTSSTSASSSRRRTEDVNNGPRTRSR--RLR.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 404
14 -9.330[O] KOG4628 Predicted E3 ubiquitin ligase  ali follow..  8  234.TCVIC--DKLRVLPCSHPY-----HTHCIDPLTENRRVCPICKRKVFTKGEARASRSRQPSLDNVTDTDDDTTPLLQQQQSNGRQVGQVSSASSAGGAAGSSSSVAAAAVAGTTRHGTFRRGHAGRNPFEESQSSDDENARINPFDRAPNLPAHLAEQLTESRRSVWSRINFASFFRRQPAVISVAAPPYLERVESGTSAMGLPVTGTIAVASPASNNILNPNLSGSFKDEDDMPPHRSIYEPIAISTPAADSATVDDSAFLQTPTQGGIGVAALPHSASDRQFLI.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 536
15 -9.310[FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases  ali follow..  15  199...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SWEVTLDDIQLARELDAIASMHIGFGTWGPHDRSGLLDSD-LVHVNRIQPHE--YEYIAESGASLSVTPEVEMMMGHGYP--ATGYLHKHRGLVTLGVDVVV---ATAGDMFAQMKFALQAERMTTNDVLTFALNGAKALKLDDKSSFNLFPLNHEPVGAVVQSARPENVDSVRPVKRHGKLLFDLDGLRNKVLAASE 438
16 -9.210[R] KOG2295 C2H2 Zn-finger protein  ali follow..  8  145......GGGDTLTQPAMLNLYTEYKTDFKRQQLNEFEEWFKNKYHPEDSVKRSEEQRGENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRR--GWITF-VNIKEICWGLNNQRLRDC--------------EMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLC-----AKIALNLDEKFR........................................................................................................................................................................................................................................................................................................................................................................................................................................ 630
17 -9.200[KB] KOG4161 Methyl-CpG binding transcription regulators  ali follow..  7  550.NLYVCPREDCR---DFLLIHIRHYHKEFAEHVSHCPKMQELAVKRTHPSSIDQVEAVPKNQIPN-QQDLQQSRSFKRQSVSATATSSTPSDITPTKALLSPKMEPPSVSPTVESGIKQEDVSLDAGPTQSFNPSLSRSCKRARLSPSKRPSGSRKSNRQRSQRRPILSDNPAGHGLTEQDVEETRQSFNTPTPDTRIDSKKRRSGAATTPISSIDSPAMGDSVSTPSSNDQTDINAALAPPPAETLSKAPQYIKENGE----------------LIRIVRMRQE............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 827
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 3 7   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.