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Query: [GOU] KOG1444 Nucleotide-sugar transporter VRG4/SQV-7, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIYTSSKSLQYLAVPIYTIFKNLTIILIAYGEVLFFGGKVTSMELTSFIMMVLSSVVATWGDQQAIAIKASSLEDLDQELVESTIFVLNPGYLWMFTNCISSALFVLIMRKRIRLTNFKDYDTMFYNNVLALPLLLVFSFIMEDWSTKNLSVNLSADSLAAMVISGLMSVGISYCSGWCVRVTSSTTYSMVGALNKLPIALAGLVFFDAPKNFLSFFSIFLGFLSGLLYAVAKQKKIQQQKVLAATLEKLast
1 -112.000[GOU] KOG1444 Nucleotide-sugar transporter VRG4/SQV-7  ali  100  1MIYTSSKSLQYLAVPIYTIFKNLTIILIAYGEVLFFGGKVTSMELTSFIMMVLSSVVATWGDQQAIAIKASSLEDLDQELVESTIFVLNPGYLWMFTNCISSALFVLIMRKRIRLTNFKDYDTMFYNNVLALPLLLVFSFIMEDWSTKNLSVNLSADSLAAMVISGLMSVGISYCSGWCVRVTSSTTYSMVGALNKLPIALAGLVFFDAPKNFLSFFSIFLGFLSGLLYAVAKQKKIQQQKVLAATLEK 249
2 -87.300[GOU] COG5070 Nucleotide-sugar transporter  ali follow..  78  98MIYTSSKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQAVAAKAASLAEGAA----GAVASFNPGYFWMFTNCITSALFVLIMRKRIKLTNFKDFDTMFYNNVLALPILLLFSFCVEDWSSVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQPLRK..... 337
3 -81.200[GOU] KOG1442 GDP-fucose transporter  ali follow..  18  105MIGANNLSLSYVTVAFYYIGRSLTTVFSVVLTYVILRQRTSFKCLLCCGAIVVGFWLGVDQESLTEVFSWR-------------------GTIFGVLSSLALAMFSIQTKKSLGYVNQEVWLLSYYNNLYSTLLFLPLIIINGELESIITYPHLASWFWAAMTLSGLCGFAIGFVTALEIKVTSALTHNISGTAKACAQTVIATQYYHDVRSALWWTSNVVVLVASAAYTRVKQLEMMRQHQQRSTATQ 335
4 -72.800[GE] KOG1441 Glucose-6-phosphate/phosphate and phosphoenolpyruvate/phosphate antiporter  ali follow..  13  138.VVGGNISLRYLPVSFNQAVGATTPFFTALFAYIMTFKREAWVTYGALVPVVTGVVIASGGEPGFHWF----------------------GFIMCISATAARAFKSVLQGILLSSERLNSMNLMLYMSPIAVIALLPVTIFMEPDVMSVTLTLGHKYMYILLLVNSVMAYSANLLNFLVTKHTSALTLQVLGNAKGAVAVVISILLFRNPVTVMGIGGYSITVLGVVAYGETKRRFR............ 355
5 -66.500[G] KOG1581 UDP-galactose transporter related protein  ali follow..  13  100TTTCQYEALKYVSFPVQTLAKCAKMIPVMVWGTLIMQKKYKGFDYLVAFLVTLGCSVFILFPAGDDVSP-----------YNKGRENTVWGVSLMAGYLGFDGFTSTFQDKLFKGYNMEIHNQIFYTTLCSCVLSFTGLILQGHLLPAVDFVSLHRDCLLDIALLSTVATASQFFISYTIRTFGALTFAAIMTTRQLASIMLSCIWFSHPLSWEQCIGSVIVFGSLYAKNLLNNKKNSQTQPPPPELPQ 337
6 -66.000[G] KOG1583 UDP-N-acetylglucosamine transporter  ali follow..  11  82.VCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLKKRYNLRQYSSVAMITAGIILCTLVSSGDVKDNTHHSLKVD--TSYSDFFWWTVGIGLLTIALLVTAYMGIYQEVIYKKYGKHPSEALFFTHMLPLPGFLIMAGNIVPLLGAIGLEWKFPLMLFYLLCNVVTQYVCISAVYVLTTECASLTVTLVVTLRKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFANVINQVRDAYRARSSRKTH 341
7 -65.400[S] KOG1443 Predicted integral membrane protein  ali follow..  16  95.IGLSNVSFQYVPLTIYTIIKSSSIAFVLLFGCIFKLEKFHWKLALSVIIMFVGVALMVFKPSDST-------------STKNDQALVIFGSFLVLASSCLSGLRWVYTQLMLRNNPPHPIHTIHQLAPIMGITLLLTSLLVEKPFPGITTVLSIVRGIVLLILPGFAVFLLTICEFSILEQTPVLTVSIVGIVKELLTVIFGIIILSERLSFYNWLGMLIIMADVCYYNYFRYKQDLLQKYHSVSTQD 393
8 -44.900[S] KOG2766 Predicted membrane protein  ali follow..  11  123..YVIVRAYQYTTLTSVQLLDCFGIPVLMALSWFILHARYRVIHFIAVAVCLLGVGTMVGADILAG-------------REDNSGSDVLIGDILVLLGASLYAISNVCEEYIVK--KLSRQEFLGMVGLFGTIISGIQLLIVE--YKDIASIHWDWKIALLFVAFALCMFCLYSFMPLVIKVTSATSVNLGILTADLYSLFVGLFLFGYKFSGLYILSFTVIMVGFILYCSTPTRTAEPAESSVPPVTS 352
9 -43.700[R] KOG3912 Predicted integral membrane protein  ali follow..  10  105..ILLFTGLYLTYATSFQMIRGAALIFVGIFSTMFLNHTLTGRHWLAIFTISCGLLDIISLDVHRVEYD-------LVTLPYTDYKSILTGDLLIIIAEILHGLQYVCEEKQLKTSNVAPLQAAGWQGIFGLGITSMLAICMDDWGDLFAALQGSISLIMTLIAFTISCAMYNFIGLYIAMYSSSANRLLADGLRVYFIWVFVIIMEWEYMNLVTIMGFLILQMGIILYR................... 342
10 -35.900[GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily  ali follow..  11  108..GLIFHALSLTGVNNVILVGRLEPTLALALSVWLLKEQINFGEFIGAIAAFIGVILTIILQPPVSDMMNMGGWQLGL------------GEFFVAAGSVALAISTIIGKKYLT--HIPLGIYSIFRTALGTVIFFFIALVLYGREHFADV--FSPFLWQWMFLYGGVIVVVGQSFWIGLKTSTVSTASLVASFTPIAGIVAAYFILSEVPTVAQYLGGGLIMLGIFLSQISKSRQTSHKSPIASTPAE 339
11 -33.600[R] KOG4510 Permease of the drug/metabolite transporter (DMT) superfamily  ali follow..  8  102.VFGMYFSLMYLSISDAVLITFMSPTLTIFLSFLLLGEPFSKLEALGSLISFSGVVLIIRPTFLFGEQTQGQQSPQDDIVETQNPKLRLIAIGVSLLGVCGLSSVYIIIRYIGNKA--HAIMSVSYFSLVTTVVAALGVLLIPSMSLQLPHSWKQ---WGLFLNLGISGFIHQILLTMGIQRERAGRGSLMTYTQVIYAVFWDVVLFHHWPNIWTWCGMAVIVSSTIWVINMRASKQNVVATAELLSTS 344
12 -31.300[R] COG5006 Predicted permease, DMT superfamily  ali follow..  9  91.......SIQTVPLGIAVALEFTGPLAVALFSSRRPVDFIWVVLAVLGLWFLLPL-------------------------GQDMSHVDLTGAALALGAGACWAVYILTGQRAGAEH--GPATVAVGSLIAAIIFVPIGAVQAGD-------ALWHWSILPLGLAVAVLSTALPYSLEIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTGIQILALCAIIAASMGSTLTIRREPQIKQVDVK.... 295
13 -29.900[S] KOG2765 Predicted membrane protein  ali follow..  12  191..YFFQLALEMDEAAMITLVSSTSSFFIICLAAVFPSATGDKLTITKVIAVAMNIGGVVA-----------------ITMNDLHDTKMTRGVLLALFSAFFYAAYLVFVKRKSDTE--EKVDIPLFFETFELP---------------------SQGQFALLFLNGLVGTVLSEALWWGCFLTSSLIGTLAMSLQIPLAILFDVLLKNKPYSPMFYMGSIPIFVALVFVSLLMRNDDSDPLMK...... 392
14 -26.800[S] COG2510 Predicted membrane protein  ali follow..  16  6..........................................................................................WQFWALMSAVFAALTAIFAKVGIQ--GINSDFATLVRTFVIIGALCLFLTVTGQWQKPGE---ISARSWLFLVLSGLATGASWLAYFRALQIGDASRVAPIDKLSVVLVALFGAAFLGERMSTINWIGILLIGCGVVLVAL.................. 141
15 -25.400[G] KOG2234 Predicted UDP-galactose transporter  ali follow..  8  152...GVLSVPLYFNPATVKMLSNLKVLVIAVLLKMVMKRRFSIIQALALLLIGISVNQLRSLPEG---------------ATAIGIPLATGAYVCTVIFVTVPSMASVFNEYALKSQYDTS---IYLQNLGIVDLFVLFSGLLSSVITNVHNLFHSRATMFLILNNAAQGILSSF----FFKYADTILKKYSSTVATIFTGIASAALFGHVITMNFLLGISIVFISMHQFFSPLAKARDEQQQNGNLELG 420
16 -24.500[R] COG2962 Predicted permeases  ali follow..  7  93.......AVNNHHMLEASLGYFINPLVNILLGMIFLGERFRRMQWLAVILAVCGVLVQLWTFGSLPIIAL----------------------GLAFSFAFYGLVRKKIAVEAQTGMLVETL-WLLPVAAIYLFGIADSPTSH------------ALSLNLLLMAAGVVTTIPLLCFTGAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEVPGADKMVTFAFIWVALAIFVMDAIYTQRKK......... 294
17 -13.600[S] COG3238 Uncharacterized protein conserved in bacteria  ali follow..  7  94VVFSEGASASALGVATFQTALISALLLSLLCDRF--KKYFTPWRITGALFAVIATIFVVSPQWHSTSFILL--------------------AILPFLAGLLAGWQPAGNAKVAEATG-SMLVSITWNFIVGFCVLGAALAIRIALGHVTIQLPDTW-----MYLGGPLGLLSIGLMAILVRGLGLLMLGVASTAGQLLGSVLIDELIPNTVYLVTIIGTLFALVGAIVTTIPEYRASKMAQRIEVSE.. 323
18 -12.200[X] KOG4831 Unnamed protein  ali follow..  8  57.................................................................................................................................................................YLMPFLLNQCGSLLYYLTLASTDTLAVPICNSLAIIFTLIVGKALGEDIGGKRAVAGMVLTVIGISLCITSSVPWTAELQLHGKGQ.. 143
19 -11.700[G] COG4975 Putative glucose uptake permease  ali follow..  11  77..ANQLKSISLIGVSTMPVSTGMQLVGTTLFSVIFLGEWSSMTQLIAMILLVTGVALTSLKAKN---------------ERQSDNPEFKKAMGILIVSTVGYVGFVVLGDIF----GVGGTDALFFQSVGMAIGGFILSMNHKTSLKSTALN----------LLPGVIWGIGNLFMFYSQPKVGVATSFSLSQLLVIVSTLGGIFILGERKDRRQWAGIIIIVIAAIILGNLK................ 287
20 -9.790[R] KOG4314 Predicted carbohydrate/phosphate translocator  ali follow..  11  400..YLYLLALKKLTATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYAD--------------------NFHADSIIGVAFAVGSASTSALYKVLFKMFLGSANFGEAAHFVSTLGFFNLIFISFTPVILYFTKVEHWSSFAALPWGCLCGMAGLWLAFNILVNVGVVLTYPILISIGTVLSVPGNAAVDLLKQEVIFNVVRLAATIIICIGFLLMLLPEEWDEITLRFINSLKEK 626
21 -9.210[P] COG2076 Membrane transporters of cations and cationic drugs  ali follow..  12  30.................................................................................................................................................................IIIFILIAVSFILLIRSYQKIPMAAAYTVFVGIGTVGTYLTG-IVLGESFSAAQMFFLALLLAGILGMKLFTKESKSQPGGEK..... 111
22 -9.120[P] KOG4505 Na+/H+ antiporter  ali follow..  8  1......MAWSQVEISKPHLAYAIIGGFTSLFMLCSLIIKEKLFLGEATMATATGLIFGPYV-FVPTSWGNTDYITEELARVLLVVEVFAAGAELLAIAACITATDPVLASSIVGKGKFAHLRNMLCNDGMAIPFLLAIYLIIEKPARHAGRDWVCIIILYECTFGCVLGAIIGVIARKMIKFSERRGL-MDRESFLVFYFVLALFCGG--GTIIGVDDLLVSFCAGAAFSWDSWFSKKTEESH...... 291
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.