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Query: [R] KOG1519 Predicted mitochondrial carrier protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPFMRKILSNMIDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVLQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFILast
1 -99.600[R] KOG1519 Predicted mitochondrial carrier protein  ali  100  1MPFMRKILSNMIDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTRDAVLQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLRKHVRAPEFATHGVAAVLAGTAEAIFTPLERVQTLLQNHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKFI 307
2 -77.900[C] KOG0754 Mitochondrial oxodicarboxylate carrier protein  ali follow..  21  2............................ATRSEETVRSLAHWQFLAGGLSGFIEIICFHPLDVVKTRMQIYTCPLDAIVKIYRYEGLSSLWKGIVPPICVETPKRGGKFLMYESLKPYFQFGAPQPTPLTHAMSGSMAAILESFLNPFEVVKITQQAHR-GKRLKTLSVVKYIIKHDGIKGLYRGITALVARNAVFHFGFFGFYNALKDIVPSPEDKTYNILRKVIIAGLASSLACVMSVTLDMAKCRIQGPQPVKYQWTISTIKSTF--KEEGFRSLFKGLGAMILRVGPGGAMLLVTYEYLFEFL 295
3 -76.300[C] KOG0758 Mitochondrial carnitine-acylcarnitine carrier protein  ali follow..  21  2..........................TTTENVSTERKANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMCFAGYALGKRLQQREDAKLTYPQIFVAGSFSGLFSTLIAPGERIKVLLQTQGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDVASKSETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAEGTYKHGIRSVFKDLI--VKDGPLALYRGVTPIMLRAFPANAACFFGIELANKFF 299
4 -75.000[C] KOG0756 Mitochondrial tricarboxylate/dicarboxylate carrier proteins  ali follow..  20  2............................ATRTESKKQIPPYMKAVSGSLGGVVEACCLQPIDVIKTRLQLYKGIAHCGSKVVRTEGVRALWKGLTPFATHLTLKYTLRMGSNAMFQTAFKDETGKVSNRGRFLSGFGAGVLEAIVTPFEVVKIRLQQQKGFKYKGPIHCARTIVREESILGLWSGAAPTVMRNGTNQAVMFTAKNAFDILLWNKDGKILQPWQSMISGFLAGTAGPFCTGPFDVVKTRLMAQSRDRYKGMVHAIRTIY--AEEGLVALWRGLLPRLMRIPPGQAIMWAVADQVTGLY 299
5 -74.600[C] KOG0766 Predicted mitochondrial carrier protein  ali follow..  18  2...........................SEIKKTEKLGVKSSKHLAAGALGGFISSTTLQPLDLLKTRCQQSSLPKMVRRIILHEGGVFSLWKGTLPSILRSTTGSSCYFYFLNWLRHFAPQSKNASSHIQNLWMGGFARAVGFAFMPVTVIKVRYESNLY-SYTTIYSSIRDIWKKEGISGFFRGFGVTALRDAPHAGLYVYFYELSKQNLHKQGTVPHRNIVNVMSGLISGATATAITNPFDMLKTRVQLE-PHIYKNFLHSAKLVY--ANEGFRGFLDGFFLRVLRKSISSTITWSVYEWALHRK 293
6 -73.500[C] KOG0762 Mitochondrial carrier protein  ali follow..  19  1.....................................MSALLDLFAGSLGGAAGVLAGHPLDTVKVRLQTYRGTFHCFKLIVQKEGFRGLYKGMSSPLLSLSAINAIVFGVHGGTCRQMED---PDSITSHFVGGCAAGMAQSVIAPTERIKLLLQIQDDKKFNGPIDATKQLLRTHGLKSLTRGFLATVARDAPAFGVYFASYEWMARSMKDGETSTLSSGQLLFAGGTAGMLSWLFNYQTDIIKSRFQAD--NSYKSYMHCIKQTY--LERGYRGFFVGLNSALIRAFPSNAATFFTVEWTYRIL 275
7 -73.300[C] KOG0753 Mitochondrial fatty acid anion carrier protein/Uncoupling protein  ali follow..  23  2...................................GEVKDWRPFVYGGVASITAEFGTFPIDTTKTRLQIYRGMTDAFVKISREEGLRALYSGIWPAVLRQATYGTIKFGTYYTLKKLAINEDGSERVWSNILCAAAAGISSAIANPTDVLKVRMQVHGKGQHKGLLGCFGEIYKYEGVRGLWRGVGPTAQRAVVIASVELPVYDFCKLQLMNAFGD--HVGNHFISSFIASLGSAIASTPIDVIRTRLMNQTPKLYSGSLDCAVQTI--RNEGLPALYKGFIPTWVRMGPWNIIFFITYEQLKKY. 303
8 -73.200[C] KOG0755 Mitochondrial oxaloacetate carrier protein  ali follow..  19  2.......................................ATSDFVLGGLASVGATFFTNPIEVIKTRIQLYKGIVNAFITVAKNDGITGLQKGLAPALYFQFIINSFRLSIYSEAMERRHNRKGEVSYGMGLLWGAIGGVVGCYFSPFFLIKTQLQSQAAKQHTSMTDALRQIYSRNGVRGLWRGSVAALPRAALGSGAQIATFGKTKALLVQYDLVTQPTLNSFSAGLIAGSIMSVAITPPDVITTRLYNQRGLLYRGWLDCFVKIL--RSEGVYGMYKGFWANYLRIAPHSTLVLLFFDELVAVR 297
9 -72.900[C] KOG0763 Mitochondrial ornithine transporter  ali follow..  21  2..........................HGGGTGNNINFVEGLIDFLAGSLGGAAQVYVSQPLDTVKVKLQTYRGMLDCFLSTYRKDGLRGLYAGSVPAVFANVAENSVLFAAYGGCQKFVAETAGDLTTVQNACAGSLAACFSTLTCPTELIKCKLQALREQDIRTPWTLTRYIWRTEGIRGFYRGLSSTFLREMPGYFFFFGSYEGTRELLRRDDQSKDDILRTMIAGAIGGVCLWTSTFPADVIKSRIQVK--NLNESMFAVGADIV--RREGVLALYRGLLPSVLRTIPATATLFVVYEYTKRAL 301
10 -72.600[C] KOG0750 Mitochondrial solute carrier protein  ali follow..  25  1............................................MNGGLAGIIGVSCVFPIDLVKTRLQNYSGIADCAKQTWRSGGFRGMYSGSGVNILLITPEKAIKLVANDFFRHKLAKEEKQLSVGRGMLAGGLAGMFQSVTTPMELLKIQMQDQGRQQKLSATQLTMKLVKENGIAALYKGLSSTLARDVTFSVIYFPLFAYLDSLAPRDGSGDAVFYGSFLAGLTSGAASSFCVTPLDVIKTRMQTINKGVYKNIPDAFVTIF--KNEGPKALFKGAACRMMVMAPLFGIAQTVYYIGVAEK 290
11 -72.500[C] KOG0770 Predicted mitochondrial carrier protein  ali follow..  17  21.PTSEGTPDQPNNNRKDDKLHKKRGDSDE------DLSPIWHCVVSGGIGGKIGDSAMHSLDTVKTRQQGYRNMISAYRTIWLEEGVRGLYGGYMAAMLGSFPSAAIFFGTYEYTKRTMIEDWQINDTITHLSAGFLGDFISSFVVPSEVLKTRLQLQSGYNYSNLRNAIKTVIKEEGFRSLFFGYKATLARDLPFSALQFAFYEKFRQLAKDGRDGELSIPNEILTGACAGGLAGIITTPMDVVKTRVQTQQPPSSNSISLSLRTVY--QSEGVLGFFSGVGPRFVWTSVQSSIMLLLYQMTLRGL 361
12 -72.500[C] KOG0761 Mitochondrial carrier protein CGI-69  ali follow..  18  8.QMENGGEEEGCRLECKEMDPLRLTTLILSADPR-YRIKPMQQVVSALVGGLITTFVVTPLEVVKTRVQTLRGAMDAFVKIVCTSGFSGLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHSTASLPYYVPMASGICSRTIVTAITPIEMVRIKMQSEYM-TYAELWRVLRSLIRQHGILGLWRGWPPTVMRDAPFSGTYWAVYEAIKRAF---SVTEPTFLFSFLTGAISGAVATFVTMPFDLITTHTQIELGQSRPSVLSRMRQIY--RLQGVRGLYVGVMPRMLRVVPACAIMISTFEYSKSFF 425
13 -72.200[C] KOG0752 Mitochondrial solute carrier protein  ali follow..  18  2.............ISGYSKELVIMSGTELD--EPGKLKRAVIDASAGGVAGAISRMVTSPLDVIKIRFQVYNGLFRTTKDIFREEGLSGFWRGNVPALLMVVPYTSIQFAVLHKVKSFAAENHAQLSPYLSYISGALAGCAAVGSYPFDLLRTVLASQGEPKVYPNMSAFLSIVQTRGIKGLYAGLSPTLIEIIPYAGLQFGTYDTFKRWSMRNPSDSLSSFQLFLCGLASGTVSKLVCHPLDVVKKRFQLN---AYKNMFDGLGQIL--RSEGWHGLYKGIVPSTIKAAPAGAVTFVAYELASDWF 322
14 -72.200[C] KOG0768 Mitochondrial carrier protein PET8  ali follow..  19  79.THEKPGPEFLKWIKPASRSSPRIQTLIKQLSVWER---AIIGAGAGGLAGAFTYVTLLPLDAIKTKLQTYSNTFDAIVKTFQAKGILGFYSGVSAVIVGSTFSSAVYFGTCEFGKSLLSKFPDFPTVLIPPTAGAMGNIISAIMVPKELITQRMQAGASG---RSYQVLLKILEKDGILGLYAGYSATLLRNLPAGVLSYSSFEYLKAAVLEKTKQSHEPLQSVCCGALAGAISASITTPLDVVKTRLMTQIGAMYTGVAGTVKQIL--TEEGWVGFTRGMGPRVVHSACFSAIGYFAFETARLTI 393
15 -72.100[C] KOG0759 Mitochondrial oxoglutarate/malate carrier proteins  ali follow..  17  2................................SNEGGVPNVVKFAFGGTAGMGATLVVQPLDLVKNRMQLYRSSMHALTSIMKNEGVFAVYNGLSAGLLRQATYTTTRLGTYAFLLERFTEKDKPLSFGMKAVLGMTAGGIGSFVGPAEIALIRMTGDGRRNYTGVVNALTRITKEEGVLTLWRGCTPTVLRAMVVNAAQLATYSQAKQALLASGKVQDGIFCHFLASMISGLATTIASMPVDIAKTRIQSMGKPEYKNAFDVWGKVI--KNEGIFALWKGFTPYYMRLGPHTVLTFIILEQMNAAY 293
16 -70.300[C] KOG0757 Mitochondrial carrier protein - Rim2p/Mrs12p  ali follow..  18  2..............................ATGGQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAITNSLMNPIWMVKTRMQLERGSKQMNTLQCARYVYQTEGIRGFYRGLTASYAG-ISETIICFAIYESLKKYLKETEKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREE-GTKYKSFVQTARLVF--REEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLL 316
17 -69.400[C] KOG0749 Mitochondrial ADP/ATP carrier proteins  ali follow..  17  1......................MGDEGGGGGHGKGDLKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVYKGIVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKFAGNLASGGAAGATSCFVYPLDFARTRLAADGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDFLP--NPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKYKNTAHCWLVIA--KQEGIGAFFKGALSNIIRGTGG-ALVLALYDEMKKYF 307
18 -69.000[C] KOG0760 Mitochondrial carrier protein MRS3/4  ali follow..  18  1...........MNIDDYESLP---------------TTSVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSNMNIVSTLRTMITREGLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRNLNYVISGAVATLIHDAISSPTDVIKQRMQMYN-SPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQNKM--NLERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQETGLTRGMIEASRKIY--HMAGPLGFFRGTTARVLYSMPATAICWSTYEFFKFYL 282
19 -67.500[F] KOG0036 Predicted mitochondrial carrier protein  ali follow..  17  150.NIPEIILYWKHSTIFDVGENLTVPDEFT--VEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIASSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQAGAPEVTMSSLFKHIL--RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
20 -66.800[C] KOG0769 Predicted mitochondrial carrier protein  ali follow..  20  1.....................................MLTLESALTGAVASAMANIAVYPLDLSKTIIQSYKNVVDCMINIFKEKGILGLYQGMTVTTVATFVQNFVYFFWYTFIRKSYRDGPITPSTIEELVLGVAAASISQLFTPMAVVATRQQTVHSAESAKFTNVIKDIYRENDITAFWKGLRTGLALTINP-SITYASFQRLKEVFHSNDAGSLSAVQNFILGVLSKMISTLVTQPLIVAKAMLQSA-GSKFTTFQEALLYLY--KNEGLKSLWKGVLPQLTKGVIVQGLLFAFRGELTKSL 305
21 -66.000[C] KOG0767 Mitochondrial phosphate carrier protein  ali follow..  17  53...........................EQYSCDYGSGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNNTYLWRTSLYLAASASAEFADIALAPMEAAKVRIQTQP-GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYF 340
22 -65.800[C] KOG0751 Mitochondrial aspartate/glutamate carrier protein Aralar/Citrin (contains EF-hand Ca2+-binding domains)  ali follow..  19  325.DIQAIDPERLKRVSQMDRLINIKAVHHKDRGVGTAFLESAYRFLLGSVAGACGATAVYPIDLVKTRMQNYKNSLDCFKKVVKFEGLLGLYRGLLPQIVGVAPEKAIKLTMNDYMRDKFTKD-GKIPLYGEIIAGGTGGMCQVVFTPLEIVKIRLQTAGEVQQAGKKIGVFTVLKELGFLGLYKGSRACFLRDIPFSAIYFPAYAHAKLASAD-EDGMNSPGTLFASAFIAGVPAAGLVTPADVIKTRLQVAARATYNGVIDCARKLI--KEEGPMSLWKGTAARVCRSSPQFAVTLLTYEVLQRLF 643
23 -65.000[C] KOG0764 Mitochondrial FAD carrier protein  ali follow..  23  1........................................................LLSPIRLFFLSVQIGSLIVGSLEQIFKREGMRGLYRGLSPTVMALLSNWAIYFTMYDQLKSFLCSNDHKLSVGANVLAASGAGAATTIATPLWVVKTRLQTQGMRPYKSTFSALRRIAYEEGIRGLYSGLVPALAG-ISHVAIQFPTYEMIKVYLAKKSVDNLNARDVAVASSIAKIFASTLTYPHEVVRARLQEQSEKRYSGVRDCIKKVF--EKDGFPGFYRGCATNLLRTTPAAVITFTSFEMVHRFL 300
24 -59.200[R] KOG2745 Mitochondrial carrier protein  ali follow..  13  5...............................PEHARAEDTEVNVWIRFGLRLGVSAALHPFEYSKTLIQLLPNIFQYAGHIRRIDGFYGCYRGLAPKLVGSLVAMVVSDRVADQLGLEQPEENKDDSFKKSLKRDIVLMVSGVVASPFHVISLRMMAQRETLYTSIVGSVAEIWKSEGIAGFFAGLVPKLLGDLACLVLSSSTIYILNKYIIKDK------LGRQYNSGFTQFAVSSLLYPLQVVSTCSAVSGSRAYRNWVDCWNDLQ--VRGELKRGSSLFWRSQSISSPVIATSFAPLPKLARY. 315
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.