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Query: [L] KOG1636 DNA polymerase delta processivity factor (proliferating cell nuclear antigen), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLELRLVQGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEGFEHYRCDRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANIVLRQNTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYKVAEMGYIRYYLAPKIEEEEDTNPLast
1 -105.000[L] KOG1636 DNA polymerase delta processivity factor (proliferating cell nuclear antigen)  ali  100  1MLELRLVQGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEGFEHYRCDRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANIVLRQNTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYKVAEMGYIRYYLAPKIEEEEDTNP 263
2 -66.600[DL] KOG3194 Checkpoint 9-1-1 complex, RAD1 component  ali follow..  11  1MFQAETVCLKQIQSTLRCID-FSKECTIEITSRGLRFAVEE-SQSLQAHAFLDKSLFQTFNFQGDYMFQTMISPLLQSLSIYTDGKECKVQYNGPGCPFIWEVEEMAGYATACELLTMECEDDVDINRLASTLCTKIIMKSNWLYDALVELDNNMGEIHTSSQKSTFLLRCVGALSTTEIEYPNEK-----SVLESFETDSENTYSYRFSLIRHALKALQVGSKVNLRIDENGTLSIQIMLGLCTFVDFCIVPLDLVSEDEE. 288
3 -50.200[DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component  ali follow..  9  1.MKYTLENARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRSMFEVYDMPPHFYCKISMKGCLAVFRNMNEVEYCELNLLDNQTNLQVNLR-CKLETTKEATISIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANSGSVVAKNYIEGARVNDKFMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLFAELNASLTLEFDEGMPFLLKIKKHGEIECLLIMSTLSPDDISFSE 267
4 -49.900[DL] KOG3999 Checkpoint 9-1-1 complex, HUS1 component  ali follow..  11  3.FKTRISNLYTLTRLVQALDKIGRFCWLRLMPETVNFVIVPDFRMTQVWSVLEVEIFEDYVVDNVINLEVPIDNFYKALRSAANASDSTVRLSKKNNQPLLSLSTTWSGRAFGSNIVTHNIPVRVLSQSYVSDCHIFLPQLNFLRHVVDKYKSLSDRIIMSANMSELQLSVNIPSARVSTKWKSQVEDISRHPSQTRAPEEFVHMRLDSKDLVNMLKISSVAKRVIACFCEGHALVLYVYITDTAVLTYYISTYVD....... 287
5 -11.600[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)  ali follow..  9  136....TMLQRTSFAVSREESRYVLTGVLLAIANGVATIVGTDGKRLAKIDAEVTLDK------SFSGEYIIPIKAVEEIIKMCSDEGEAAIFLDQDKIAVEC-------DNTLLITKLLSGEFPDFSPVISTESNVKLDLHREELITLLKQVALFTNEVKFSFLPGELTLTANCT-----------KVGEGKVSMAVNYSGELLEIAFNPFFFLDILKHSK-DELVSLGISDSYNPGI---ITDSASGLFVIMPMRLHDD.... 366
6 -4.820[L] KOG4557 Origin recognition complex, subunit 6  ali follow..  10  12..RLGLAEPDMLRKAEEYLRLSRVKLDLAASWMKCPLDRAYLIKLSGLNKETYQSCLKSFECLLGLNSNIGIRDLAVQFSCIEAVNMASKILKSYESSLPQTQQVDLDLSRPLFTSAAL-CKILKLKVDKNKMVATSGVKKAIFDRLCKQLEKIGQQVDREPGDVATPPRKRKKIVVEAPAKEMEKVEEMPHKPQKDEDLTQDYEEWKRKILENAASAQKATAE....................................... 252
7 -4.800[S] COG2859 Uncharacterized protein conserved in bacteria  ali follow..  9  92......FKGNVPGELFPKLEEAQKKIVAELNAQGINEKEIILGQWTSKRTD-DDPTMPRYNADGSVTIKTNVAAVEKVVAKLNE-------------------------------LQVATDGAIAESKVAYRFNGIGALRAEMIAAATKDARNAALQF---ATDSGSQVGSISDASQGVFQIFASGSDEDDPTAINKTVRVVTTVTYALQ..................................................... 266
8 -4.350[S] COG4856 Uncharacterized protein conserved in bacteria  ali follow..  6  43..................DSEVIENVPVKVYYDKTNLYISGIPETVTVTLSGPRSIVQSAKAQQDFTVYADLKNA-----------------SIGTQEVKLQVKDVSDRLKVKVNPATVNVNVQEKVTKKFSVDVELSKSVIADGYQAGTPIIDPKKVSITGAKDTIEQIAYVKATLESDGKHKSEFTDKATVSVFDSNLNKLDVEVSPQEVEVTVPVEKVGKSVPVKIKQEGTPESDIEISS.................... 250
9 -4.300[U] COG5043 Vacuolar protein sorting-associated protein  ali follow..  9  1..........MLEGLLNFLNRLLGEYIENFDATQLKVAV--NGDVTLRNLQLKRSAFRKLELPEELTLKIPWSSLKNKPVEIYIVGIRALASMEENVKSQSEVDPHQVLESKRRQMQLWEASQIGKAETAYDPKTQ-TFTESLITRMIDNIQINIRDIHIRF-EHLPVSNVVPGGYSFGLLLSEFSIESCNEEWTSTFVETESQTIYKLCSLRGFGIYSDETAECIDKTDINE-FQALITDFQSREKDYIIAP--KLPTPEIP 270
10 -4.210[S] COG4848 Uncharacterized protein conserved in bacteria  ali follow..  8  1...MKMTSRKLSDILKQRLQHENRSFLFDREKDTLRVEDQTTKKGITLDL---PPIIAKWELKKDEAIDEIVYYVSEAMTAMEGKAQ---EMTGKETRIYPVIRSTSFPDKSSEDIPLIYDDHTA------ETRIYYALDLGKTYRLIDQ----RMLEKENWTKERIRETAAFNLRSLPTVVKEDTVAGNYFYFFRANDGYDASRILNEAILNEYKQHAEGELAISV---PHQDVLILADIRNESGYD--LGQMSMSFFAGGT 240
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rodrigues AP, Grant BJ, Godzik A, Friedberg I. The 2006 automated function prediction meeting. BMC Bioinformatics. 2007 May 22;8 Suppl 4:S1-4.