current user: public
If you have questions about the server, please let us know.

Query: [I] KOG1684 Enoyl-CoA hydratase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350
# Score Template Links and tools%idFirst MALSVRQSSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTGDKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCPDADDVPELLQKYHSPPEKPFSLQPVLEQINKNFSADSVEGILENLQNDGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQKPQWQPTKLADVTEEHVQWFFRKLPDTEELKLLast
1 -130.000[I] KOG1684 Enoyl-CoA hydratase  ali  100  1MALSVRQSSSSVLATESSNKGMIILNRPKALNAINLEMVRKIYKHLKKCEKSKSLVIIKGTGDKAFCAGGDVRALVEAGPTDESKSFFREEYSTNALIGNYKIPYIAIIDGITMGGGVGLSVHGKYRVASDRTLFAMPETAIGLFPDVGGSYFLPRLQGKLGLYLGLTGYRLRGADVYYSGIATHYCESSKIPDLETALLNCPDADDVPELLQKYHSPPEKPFSLQPVLEQINKNFSADSVEGILENLQNDGSEWAKKTLETLSKMSPTSMKVTFRQLELGSQLSLAQCLIMEYRLAVRHLERSDFKEGVRALLIDKDQKPQWQPTKLADVTEEHVQWFFRKLPDTEELKL 351
2 -51.500[I] COG1024 Enoyl-CoA hydratase/carnithine racemase  ali follow..  23  1....MCEEFKDIIYEEKGQVAWVTLNRPATYNAFTPVMNREVTVALKKANQSDAIIVLTGTG-RAFCSGEDLDGV--TVDTDHGAILRARYHPMMQGMKQVEKPIIAAVNGTAAGAGMSLALAADFRLVHENAKFVSAFLGVGLIPDSGFLYQLPRMIGAKALELAVLGKPLSAEDAQRCGLVTEVFAADEWEDGVASFS------------------------------------------------------------MKLAALPTKAIGLIKRLMIDGMNEGFLEVLEKEAQAQRIAGQSADHREGLEAFK--QSRPPMFT........................... 258
3 -47.100[I] KOG1680 Enoyl-CoA hydratase  ali follow..  27  3.........TLSRTGAAENVALITLNRPSALNALCRELMLELSENLLKVEKDQSYVIVLTGSEKAFAAGADIKEMAKLEFADVFENDYFTNWD---TLSHITKPVIAAVNGFALGGGTELALMCDIVYAGENAIFGQPEITIGTIPGLGGTQRWPRYVSSVAMEICLSGDRLGAQEAKEDGLVSKVFPVQQLVG-------------------------------------------------------------AVLLADRIAKNSPLIVKTVKRSLNSAYQTSLNQGLEMEKQLFQSTFATNDRREGMSAFA--EKRAPKWT........................... 254
4 -46.300[H] COG0447 Dihydroxynaphthoic acid synthase  ali follow..  16  15WIDHSEGYSDIRYHKSTDGIAKITINRPEVRNAFRPQTVKEMMTAFSDARFDENIIVLTGEGEKAFCSGGDQKVRGDYGGYKDDSGVHHLNVDFQRDIRSCPKPVVAMVAGYAIGGGHVLHMLCDLTIAAENAIFGQTGPKVGSFDGGWGASYMARLVGKKAREIWFLCRQYNAQEALDMGLVNTVVPYADLEKETVRWC------------------------------------------------------------REMLRNSPIAIRCLKAALNADCDGQA-GLQELAGNATMLFYMTEEGQEGRNAFN--EKRAPDFS........................... 279
5 -40.500[I] KOG1679 Enoyl-CoA hydratase  ali follow..  24  1.....................................MVETFNDVLEDIKKDNGSVVLRSLSPGIFCAGADLKERKGMTPEE-ATEFVKELRGLLIAIEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRILSALAKELIFTARVFNGAEAKDLGLVNHVVKQNE--------------------------------------------------------TQDAAYQQALKLAEEILPNGPVGVRMAKLAIDKGMQVDLATGYSIEEICYSQVIPTKDRLEGLAAFA--EKRKPVYK........................... 231
6 -40.300[I] KOG0016 Enoyl-CoA hydratase/isomerase  ali follow..  15  50.LTESASTYRDIVVKKEDGFTQIVLSRSTEKNALNTEVIKEIVNALNSAAADDSKLVLFSAAGSVFCCGLDFGYFVKNNRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPAIGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGASANEMLIAGRKLTAREACAKGLVSQVFLTGTFTQ-------------------------------------------------------------VMIQIKELASYNPIVLEECKALVRCNIKLELEQANERECEVLRKIWSSAQGIESMLKIPLLGPRKTQND........................... 323
7 -28.300[I] KOG1683 Hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase  ali follow..  15  22FSQSAFAVHSTHRVEKQGDVAVMKIDLPTTENVLNKALFAEMNETLDRLQSDQSVIVVMSGKPNSFVAGADIQMFKAEKTAAGVSNLLREGQKQLLTIELSQKPIVAAIMGSCMGGGLEIALACHYRIAVNKTLLGLPEVTLGIMPGDGGTQRLPKLTTQNVLDLTLTGKRIKANKAMKIGIVDRVIQPL---GDGICTSTETTHKYLEEIAVQSARELANGKLKINRDKGFVHNATQAVMTSKFVLDNVILKMAKNKLIKLTNGNYPAPLKIL--DVVRTAYLDPKNGYEAEAKAFGELSQTFQSKALFGLFEGSTNKNKYGKGLPVNEI.................... 355
8 -5.860[C] COG1062 Zn-dependent alcohol dehydrogenases, class III  ali follow..  12  57...........................PVVLGHEGAGVVVEVGEGVTSVKPGDHVIPTAECGECEFCRSGKTNLCVAVRETQGKGLMPDGTTRFSY-------------NGQPLYHYMGCSTFSEYTVVAEVSLAKINPLGCGVTTGIGAVHNTAKVQGAIGL--VVQGARQAKAGRIIA--ATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQS--------VIIGVAGSGQEISTRPFQLVTGRVGRSQLPGMVEDAMKGDIDLEPFVTHTMSLDEINDAFDLMHEGIRTVIR.................................... 368
9 -5.850[IQ] KOG1394 3-oxoacyl-(acyl-carrier-protein) synthase (I and II)  ali follow..  14  195...................IPYAITNMGSALLAIDLGLMGPNYSISTACATSNYCFHIRRGEADMMIAGG-----TEAAIIPIGLGGFVACRALSQR-QTASRPWDKARDGFVMGEGAGVLVMESLEHAMKRGAPIVAEY-LGGAVNCDAHHMTDPRADGLG-----------VSSCIERCLEDAGVSPEEVNYINAHATSTLAGDLAEINAIKKVFKSTSGIKINATKSMIGHCLGAAGGLEAIATVKAINTGWLHPSINQFNPEQAVDFDTV----NEKKQHEVDVAISNSFGFG-----------GHNSVVAFSAFKP.............................. 473
10 -5.750[Q] KOG0022 Alcohol dehydrogenase, class III  ali follow..  11  56....................GNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFT-------------CSGKPIHHFVGVSTFSQYTVVDENAVAKIDAIGCGFSTGYGSAVKVAKVTGGVGL--VVMGCKAAGAARIIA--ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS--------VIVGVPPDSQNLSINPMLLLTGRTSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGIRTVLT.................................... 374
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 5   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Flexible structure alignment by chaining aligned fragment pairs allowing twists. Bioinformatics. 2003 Oct;19 Suppl 2:II246-II255.