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Query: [T] KOG1701 Focal adhesion adaptor protein Paxillin and related LIM proteins, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDLLast
1 -131.000[T] KOG1701 Focal adhesion adaptor protein Paxillin and related LIM proteins  ali  100  1MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLDDSSALPSISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 612
2 -56.900[TZ] KOG2272 Focal adhesion protein PINCH-1, contains LIM domains  ali follow..  18  5........................................................................................................................................................................................................................................................................................................AMHCTRCADGFEPTEKIVNSNGELWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPCCNKCGEFVIGRVSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEVCQKCHGLIDEE--PLRFRGEVYHGYHFSCTACGTELDSTAREVKSNELYCLRCHDKMGPICGACRRPIEERVVTALGKHWHVEHFVCAKCEKPFLGHRHY-EKRGLAYCETHYHQLFGNLCFVCNQVIGGD-------VFTALNKAWCVHHFACSVCDTKMTQ--KSKFYEYDEKPVCKKCYDRFPNELRRRLRTAH 327
3 -55.700[TZ] KOG1044 Actin-binding LIM Zn-finger protein Limatin involved in axon guidance  ali follow..  25  1..........................................................................................................................................................................................................................................................................................................................................................................................................................MYGTRCHGCGEFVEGE--VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRPMSSSPKETTFSNCAGCGRDIKGQALLALDKQWHLGCFKCKSCGKVLTGE--YISKDGAPYCEKDYQGLFGVKCEACHQFITGK-------VLEAGDKHYHPSCARCSRCNQMFTEGE---EMYLQGSTVWHPDCKQSTKTEEKLRP... 196
4 -44.200[K] KOG4577 Transcription factor LIM3, contains LIM and HOX domains  ali follow..  19  28.............................................................................................................................................................................................................................................................................................................................................................................................................................PQCAGCNQHILDK--ILKVLDRHWHSSCLKCADCQMQL-ADRCFSRAGSVYCKEDFFKRFTKCTACQQGIPPTVRKAQDFVYHLHCFACIICNRQLTGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRT-------TITAKQLETLKNAYKNSPKPARHVREQ---LSSETGLDMRVVQVWFQNRRAKEK..... 213
5 -41.600[TZR] KOG1704 FOG: LIM domain  ali follow..  14  32............................................................................................................................................................................................................................................................................................................................................................................................................PASRIRIAADAHRHSTSDDDSGCALDEYAW--VPSGLKPNMVHAYFACLPENRQSRYQLPPQDSDVRYCEDLNAEEADTCEKMLQGFGDECLEAEGRSWHFHHFQCAQCNDVLADQKYMQ-RANKPVCLKCFHSSSSFSCTTCRLSFSS-----DTPHMSQGDLHWHAECFCCCVCSKNLL---GVKYSRVGESLFCGYQTCGGEDEELLDEDR.. 307
6 -41.500[R] KOG0490 Transcription factor, contains HOX domain  ali follow..  18  1...........................................................................................................................................................................................................................................................................................................................................................................................................................MMVHCAGCERPILDR--LLNVLDRAWHIKCVQCCECKTNL-SEKCFSREGKLYCKNDFFRRFGKCAGCAQGISPSVRKARSKVFHLNCFTCMVCNKQLSGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLKAKQLETLKAAFAATPKPTRHIREQLAQETG............................... 218
7 -21.600[K] KOG2461 Transcription factor BLIMP-1/PRDI-BF1, contains C2H2-type Zn-finger and SET domains  ali follow..  10  449..............................................................................................................................................................................................................................................................................................................................................................................................SPAFGGGGGMGGGFGMGGSAHTSSFHQLPFVNSSSHNDSSFNGVPN----YVQQQENG-YACKDCNKTFGQLSNLKVHVRTHTERPF-----KCEICTKEFTQLAHLQKHHLVHTG-HRCDICDKRFSSTSNLLHNGQKPYCDVC--AKFTQSCGTCGKKYISPSGLRTHWKTTT-DMKDSMR-GEIDEGSMSGSGYGNLGIFENSELKRLMPIGQGPSGMQEQQAPP.. 724
8 -19.400[O] KOG2231 Predicted E3 ubiquitin ligase  ali follow..  17  46.............................................................................................................................................................................................................................................................................................................................................................................................................................NACVVCFKNVE-----IFSIGDCDHPVCYECS-----TRMRVLCQQNECPICRHVLSKVL-PCPKCDAPPYRTFLRNHVRSEHKLLY-CDLCVETLN---FTFER--RCYTQAELQLHNTPLCEYCNKRYVDRDELFRHL------RREHYFCHFCDADGCNYNDYADLAEHFRAEHFLCEKCATEQF........... 272
9 -18.300[R] KOG3608 Zn finger proteins  ali follow..  15  178..............................................................................................................................................................................................................................................................................................................................................................................................................................NWAMCHKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSF--QCAQCFKFFATKKLLKSHVVRHVNCYKCTMCDMTCSSAS-YRHLKDKPL-----------KCSECDTRCVRESDLAKHVQIVHSKTVHHPDCYACHCCERFFKSGKSLSAHLMKKHGFRLPSGHKRF--TYRVDENGF 393
10 -18.000[K] KOG2462 C2H2-type Zn-finger protein  ali follow..  9  117..........................................................................................................................................................................................................................................................................................................................................................................................DEHICPECGKKYSTSSNLARHRQTHRSIMDKKAR--HCPYCEKVYVSMPAY--SMHVRTHNQGCECQFCGKRFSRPWLLQGHIRTHCGVCEKAFADKCARCGKAFALKSYLYKHEESSKNRGGVPGSGAASGNRPPSSPKRQQAECAASDSAKSTRQAAMAFQGFPAGPEVTAYSHATSAQEEYHRV-YQDLLPNRHVPLALPLAMPYHQSDPTVQEQHSAKTSPNYAMVA... 442
11 -17.800[R] KOG4377 Zn-finger protein  ali follow..  11  1M-------PKAQHSP----------------QAIFTSFKLERSEYSGPGARLPGGSSSTVATAEDRLSLADHDGSATDLTPSRYRKRGRVWAPTSSLEQPSKRIVNQPTHFGARSETESRSSRHESLAQPTLQPSEPLETNSSTNLSSTILDKVSVVRAAGTFYPENANSAAQGETPEVVSSRYNSRQESNDLEVDQPEDLSMRPSLPEATATPAVVGPALNMNLLQFKQLIDLYQRQVLLPSFLAAASQPLALPGSAAGPGVSGPLLDMRILLENAAQQKLMLLNAAASATASAVAATTINSGQRTAAKRNRDHDIPSGYLK-----------------------------------------------------------------------------------------FRFNEDCGFE------RCGYRNHQSH---FHCNDCHYSFCDKT-RHERMDTLMGDDFRQF-MQCGSCGIDPTEAVTASSRKTSH---FHCRKCDYVCTDSN--LHLRQDYVRNAGFRKVG--GNEQCDSP------------CSYAQRHTH---YHCVTCDGGVLSRAQLAAHKHRTG-----------FPKQEADTTP. 493
12 -16.400[S] KOG4367 Predicted Zn-finger protein  ali follow..  13  9..............................................................................................................................................................................................................................................................................................................................................................................................................................KCPVCGSFYR-EPIILPCS----HN---LCQACARNILVQT--PESESPQSHRA-SAPTTPCQKSPNGVRVFLSPALAPVPRNSCITCPQCHRSLI-DRYQQSKAAALKCQLC-PKEATVMCEQCDVFY-------------------------CDPC-VPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPV 248
13 -16.300[R] KOG4299 PHD Zn-finger protein  ali follow..  6  2.......................................................................................................................DAKPWNHTSEAFQASILEDLKIIQKAGAERNAKSSHGSINSRSASPNKATSRRNRAQNGNSNGRASVDNSDDGSKDDLDYSPSVKRKHVNGEGAEKGDHDTSNNGPSITKLRRKVRRTYDTKDGFVAWNTLDDDFRPIVPDQERSRKINPQKGNNNNLLKENKSLKTTAKDLSDISSSSMKKANNSSKPLFSGKLTFKANIPVPTSEVVTENNVTRNVTVYSNQKHLGNESENFND--------------------------------MEGRAEDISSNELLPTPEEYPYRYNNDYCSACHG--------------------------------------PGNFLC----------CETC-------------NSFHFTCWYCNECKHHSLYNELDEQEELEILCFRCHKSALVSQCDYCN-------------------SYWHPDCWKCPNH........................................ 456
14 -15.700[R] COG5048 FOG: Zn-finger  ali follow..  9  177......LQQQQELREQLRAQQEANKKLELELKQTQYKQQQLQATLENSDGPQFLSPKRKISPASENVEDVYANSLSPMISPPMSNTSFTGSPSRRNNRQKYCLQRKNSSGTVGPLCFQELNEGFNDSLISPKKIRSNPNENLSSKTKFITPFTPKSRVSSATSNSANITPNNLRLDFKINVEDQESEYSEKPLGLGIELLGKPGPSPTKSVSLKSASVDIMPTIPGSVNNTPSVNKVSLSSSYIDQYTPRGKQLHFSSISENALGINAATPHLKPPSQQARHREGVFNDLDPNVLTKNTDNEGDDNEENEPESRFVISETPSPVLKSQSKYEGRSPQFGTHIKEINTYTTNSPSKITRKLTT-----------------------------PRGSIDKYVKEMPDKTF------ECLGCTKTFKRRYNI--RSHIQTHLE-YSCDGCDKAFVRNHDLIRHKKSHQEKAY-----ACP-CGKKFNRE--DALVV--HRS-YENVVIKRSPRKRGRPRKDGTSSVSSSPIKENINK--DHNGQLMFKLEDQLRRERSYDGNGTG-VSPMKTNQ......................................... 708
15 -15.500[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  10  682.......PKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPPP............................................................................................................................................................................................................................................................................................................................................ 954
16 -14.500[K] KOG1244 Predicted transcription factor Requiem/NEURO-D4  ali follow..  20  272..........................................................................................................................................................................................................................................................................................................................................................................................................................................................YCDFCGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAV-----KTYRWQCIECKCCN----------------ICGTSENDDQLLFCDDC-------------------DRGYHMYCWSCHLCLD...................................... 376
17 -14.400[T] KOG4825 Component of synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding glycoprotein (43kDa)  ali follow..  20  753..............................................................................................................................................................................................................................................................................................................................................................................................................................LCIFCGE--RSESFTEEGLDLHYWKHC-RCDHCKQVVEISSLTEH-----CDK--KDGFGKCYRCSEAVFKEELPR-----HIK----KDCNPAKPEKL-------------------ANRCPLCHENFSPG------------EEAWKAHLMGPAGCTMN..................................... 872
18 -14.400[R] COG5141 PHD zinc finger-containing protein  ali follow..  15  196..............................................................................................................................................................................................................................................................................................................................................................................................................................RCVICNEAECENSNAIV----------F-CDNCNTSVHQNCYFVPEGQWFCKKCLLHEVICCAFCPDR--GAFCTTLDGRWHTICFHDTSRLDLVRNIASIPKSRWKLVCCICKLRWGT--CVQCSD--------------KNCYAAYHITCARRAGFFYKIYSHSASY--SVDMETYCDK................. 361
19 -14.100[O] KOG1814 Predicted E3 ubiquitin ligase  ali follow..  15  161..............................................................................................................................................................................................................................................................................................................................................................................................................................................NAKLLEFQIRKFQCNVCFDEFNGTDCFQLTGHVSCQSCLRDYYTKCLDCGKDAPVLTLKELESIVGVQLTNCSFCQGPSKRD----PGQKLAICQKCDFAF----CSFCQATMYLNYQENEPEKALELEKRYGKRIIDCPTCDRVVERIDG-------CHMNC-LCGTH-----CFLCGAYL 400
20 -14.000[T] KOG1829 Uncharacterized conserved protein, contains C1, PH and RUN domains  ali follow..  9  3.............................................................DPSKWFGRAPYQQVGDTDDPIIEVDQISFTSSCSSGEHEGYVTARDTTKNRVNGDSVNDLISFEEDLNLPGTSEENSLLSPDSPSSSTPNFPPQYESQNLKESVIVRNSIFWFTESEVDAAKLVLPISNKGRVCRFDNDVDDNLLETTCRTLQISMGLCERSRWLNHLARDPVMSRLVRELDEDFASTSDEPEDQGAENGEEVSRPPASSFSSSSGSYHTIVGILDETVQLNPLNPGMTRVIVPARRGIQSVDIRRRINETPSAVCSAIIRQAVQKDPPIDQRMMEWMRGFAEVGTWIQEVAPASRKHDKYSYEVPPLSEDWILTIHKQPPIRQGLESQQW------------KCAACRQSLHTHNINDREQCPRF---CFFCSLCHRAVRESPVFDLPGDLVCIDAFSEHIIHCKKCRLQ-----------------PVCVRCN----------DMTDRLF----FEERAVSRCEGCGH--------------------SHSPKCPCPKCAR...................................... 575
21 -13.900[R] COG5236 Uncharacterized conserved protein, contains RING Zn-finger  ali follow..  12  63..............................................................................................................................................................................................................................................................................................................................................................................................................................LCVICARKLT-----YVSLTPCHHKTCHICLICRTENEEVMFTDRIDGDIYGINFTSE--FCPLSKDEQVCDFGSFKKYNEHLKCLICATHKHAFPCELEIFTQNGHPMCAFCSGKRFYSKCHICDK--MNPASPQYFKDYNQLFDHFKHSHYVCTVQT-------------------CLDNKFVVFKDE........ 296
22 -13.800[R] KOG3002 Zn finger protein  ali follow..  17  53.......................................................................................................................................................................................................................................................................................................................................................................................................................................................ELLECPVCTNLMYPPIHQCPNGHTLCSSCKLRVQNTCPTCRYELGNIRCLALEKVAESLEVPCRYCQDIF---PYYSKLKHEQHCR------FRSSCSECS........................................................................ 153
23 -13.700[R] KOG1819 FYVE finger-containing proteins  ali follow..  7  277.....................................................................................................................PTELTKLETVLCKGESAVPEDTSSTLTMSDFRTNATDEEKAKNNQRVWMCDMPSDSTSSLDSSVQDSSSETTSLASSALASPHSGSEENVSQIENEEGDDEAIGTNSNSSNEVTESPETIEEPDNVDMEESSESEVDTHIDETRNESDDEITDDVQASDVLQVETKKCKSSRLLEQKKFDKSVKTIIPMQTDPRSQIDPKNLRSRFRSSEDLVHRLFVCIAGVADQLQTNYSSEIRKVLKLILQPSEIIPVYEVVNAQVANSQTEGEETGVEAQETLPLPAFMGVR------DEDCEQCTACSMPF-------NFVRRRHH-----CRNC-------------GRIFC--------HKCSCNTISIPEHGYDRKPV-------VSSPQSNLS....................................................................................................... 625
24 -13.700[KL] COG5151 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1  ali follow..  16  311...............................................................................................................................................................................................................................................................................................................................................................................................................................CPRCKAKVCT----------------IECPSCSLVLILSTHLARSYHHL-LKNWSEI-THCFACQLPFPKPPVSPFDESTSSMRYACPSCKNHF--------------------------CLDCDVFA-------------------HEQLHECYGCQCSGN................................... 421
25 -13.700[KL] KOG2807 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1  ali follow..  16  311...............................................................................................................................................................................................................................................................................................................................................................................................................................CPRCKAKVCT----------------IECPSCSLVLILSTHLARSYHHL-LKNWSEI-THCFACQLPFPKPPVSPFDESTSSMRYACPSCKNHF--------------------------CLDCDVFA-------------------HEQLHECYGCQCSGN................................... 421
26 -13.500[O] KOG0006 E3 ubiquitin-protein ligase (Parkin protein)  ali follow..  16  204.....................................................................................................................................................................................................................................................................................................................................................................................................................................................NSRNITCITCTDVRSPVLVFQCNRHVICLDCFHLYCVPCGCPNSLIKELHHFRI-QQYGAEECVCPGCGAGLDQRKVTCEGGNGLGCGFAF-------CRECKEA---EQARWEAASKETIKKTTKP----CPRCHVPVEKNGG-------MHMKCPQCRLE-----CWNCGCE. 424
27 -13.500[O] COG0068 Hydrogenase maturation factor  ali follow..  14  104............................................................................................................................................................................................................................................................................................................................................................................................................................AATCPECQREIFDPF------SRFYRYPFTNCTHC-----GPRLSIIRAIPY-CNTSMSAFVMCPECEDSYHDV----ENRRFHAQPVACHTCGPKA----WLERADG---------KPVTASMFSMLDDVDAVCTLLQKGEIVAIK-GFHLAC---EAAVEKLRQRKRR-----YDKPFA................... 255
28 -13.000[S] KOG4623 Uncharacterized conserved protein  ali follow..  13  42..............................................................................................................................................................................................................................................................................................................................................................................................................................NCWFCNGNVR-------------DRNSWTCPSCEQ-----NGFTKDGD------YNRDITSCDQCAQRLKVEKLS----QFEPK-----------NESRFDQELKV--Y-RERLEKQF-RLCSSCERHVNKVLHEKKKMVLSSK...................................................... 189
29 -12.700[S] KOG3990 Uncharacterized conserved protein  ali follow..  16  4......................................................................................................................................................................................................................................................................................................................................................................................................................................................KVLFACSKCFSRHLYEEL---SGQQLCKGCRGST-GKCTYCRSEFQPATKSQ----------ACKKCEHYLGKYG---------CC-KIVAAFGGSKCMRCAS-----------------YEAKYGPPVQCDECKLRSAFDRRDENKKVNGKLLCWLCACA............. 133
30 -12.600[OU] COG5082 Arginine methyltransferase-interacting protein, contains RING Zn-finger  ali follow..  13  62..............................................................................................................................................................................................................................................................................................................................................................................................................................KCNNCSQR---------------HKDC-ICSYCGAT-------DDHYSRHCPK------IQCSKCDEV-------------H-QC-QCTLCKSK---------------CPSIWRAYILVDCYNCGGK--------------------HFG--DCKEKRSSRVPNEDGSAFTGSNLSVELKQ................ 204
31 -12.500[O] KOG3579 Predicted E3 ubiquitin ligase  ali follow..  10  98.RPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDSSLATSAP-----------------------------------CCTLCHERL-EDTHFVQCPSVPSHKFCFPC--SRQSIKQQG---ASGEVYCPS------EKCPLVGSNVQGEIATILAGDVKVK.................................................................................................................. 555
32 -12.300[S] KOG4260 Uncharacterized conserved protein  ali follow..  12  29.............................................................................................................................................................................................................................................................................................................................................................................................................................PPCRACTQLVSSFRAGLERTKRGHAGGDTAWEEEKLRSYKNSEVRLVEEKLCSEGEVINKDHCHNLAN-IDQLTVCCPLNTYGPDCLTCTECNGN-PEHYESFRDEKKLLCTQCHAA--PKSCRKCKKGWSMDSEAGCVDINECLEQQRPNPCFSCLECDRS-----------------CDGCDGD--PDMCRKCAD.. 282
33 -11.800[T] KOG3512 Netrin, axonal chemotropic factor  ali follow..  13  402...................................................................................................................................................................................................................................................................................................................................................................................................................GGRCKCNGHASECVATVSSGSGTALSDQDDGQDEDTPSAPSLANHFGRSTQMSAKLTMTCACK--HNTAGPECERCKPFYFDRPWGRATDNDANECKMCRRCRFNLELYKLSGRVSGGV-CYNCQHDTTGRYCHYCREGYYRDATKPPNHR-------------VCKRCDCHPVGSTGKTCNHLSGQCPCKE---GVTGLTCNRCA... 595
34 -11.800[C] KOG2282 NADH-ubiquinone oxidoreductase, NDUFS1/75 kDa subunit  ali follow..  14  42.....................................................................................................................................................................................................................................................................................................................................................................................................................................MVEPGTTVLQACEKVYHER--NCRMCLVEIEKAP------------------KVVAACAMPVMKGWNILTNSE-HPDCPICDEC--DLQDQSMMFGNDRSRFLEG-LVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQ-FMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDA... 256
35 -11.600[C] COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)  ali follow..  13  14.....................................................................................................................................................................................................................................................................................................................................................................................................................................EVNGADNLLEACLSLWHPA--ACRQCAVKQYQN---AEDTRG----------RLVMSCMTPASDGTFISIDDE-HPDCPVCENCH--LQDMTVMTGHSFRRYRFT-FISHEMNRCIACYRCVRYYKDYADGTDLGVYGAHDNVY-LESEFSGNLVEICPTGVFTDKTHSERYNRKWDQFAPSICQQCS... 234
36 -11.600[L] COG0551 Zn-finger domain associated with topoisomerase type I  ali follow..  10  6..............................................................................................................................................................................................................................................................................................................................................................................................................................KCPTCGRNMASTGVFLGCTG---YALP-RCTKCGTAMAHRKIHICGNNPNCDKGYDGPVVECDKCGADM----HLKLGRF---KYMGCTNCDNT----RKILKNGEVAPPKEEPVHFPELKCEKSDAYFVLRDGASGVFM----------SAHNFPKSRVQYRERLPEKLAYLADAPQKDPE--KATKWIVDFTNGKW 265
37 -11.500[K] KOG4218 Nuclear hormone receptor betaFTZ-F1  ali follow..  27  40...............................................................................................................................................................................................................................................................................................................................................................................................................................CPVCGDKVSG-----------YHYGLLTCESC------KGFFKQNNKRYCIE---------QNC--------IDKTQRK------RCPYCR---------------------------QKCLSVG........................................................................ 104
38 -11.400[K] KOG2482 Predicted C2H2-type Zn-finger protein  ali follow..  13  135...................................................................................................................................................................................................................................................................................................................................................................................................REELQKQRLREILEQQQQERNDTNFHGVCMFCNEEFLGNRSVILNHMAREHLDNLQCLYCEKTFRDKNTL----KDHMRKKQHRKINPKNREYDRFYVINYLELGKSWEEV-AVCLFCEKQAETIEKLYV-----HMEDAHEFDLLKIKSELGLNFY-----QQVKLVNFIRR--QVHQCRCYGCHVKFKSKADLRTHMEETK...................... 368
39 -11.200[S] KOG4617 Uncharacterized conserved protein  ali follow..  13  44...........................................................................................................................................................................................................................................................................................................................................................................................................................................................CQKYVEKLAVV----QSEMVACATNWSIPPVVCTKCFQNYINQFEYETKNLNNVYSLDNRTCSQVIYDNY-YSTDISKALTSEIWEK---SRCDSCITIKWNFPQNKSEVSFSERTMQFQNNCVICNLCKTTFDELFGWKIYTTPDVDFCVDVETTMNDTI--KCAEK. 239
40 -11.200[R] KOG4684 Uncharacterized conserved protein, contains C4-type Zn-finger  ali follow..  15  57..............................................................................................................................................................................................................................................................................................................................................................................................................................NCRVCQSLIN--------LDGKLHQHVVKCTVCNEATPIKN--PPTGKKYV---------RCP-CNCLLICKDTSR---------IGCPNCRRNLGPVMLISEEQPAQPALPIQPEGTRVVCGHCGNTFL-------------WMELRFNTLAKCPHCKKICSSSVGSAL............................ 189
41 -11.100[O] KOG0320 Predicted E3 ubiquitin ligase  ali follow..  10  2.....................................................................................................................................................SDSTIFRFNSSILDQSADSNVSSSSSNSSVSDSSVDSHSSIESNSGHNTSVESQSSAESDSSADSHSSLERPSPVERDLSVESDSSSATNTSESSVGEASNQLQSPQSNNPLNMANLSVSTEDAHSQIRSLTQDVIQMEAELDRMNRYCEEVVAQIDTFATRTSTPTTRRIRRRTSPVEVIDLSHLDRAPPVRSARNRDPDAFIDLCTPEGPRSRTVNLHSNDSLTILPRRSAENDPVVDLDVASPPKRVNRDIDESQKEELY--KCPICMDSVSKREPVST-----------KC----------------GHVFCRECIETAIHKCPICNKKLTARQFFRI---Y..................................................................................................................... 318
42 -11.100[R] KOG1280 Uncharacterized conserved protein containing ZZ-type Zn-finger  ali follow..  9  207.......................................................................................................EILQQTETVLMQHRSSRVPDMEAIESFVRVIEDQVVTSMADRRQRLGASSSSLHRLTRIEAISPGTNTALAMGMRAAMPVLVDQPTTMVRRQTARRTGEPIGIALQSAVASSSRSGKAGSSSGVAKAQTKTQGDQPTKKVSTVITSPLKDKRFLCSESKLLKATFTEAMFCSMLADEELFQPPIGLPWTANFMLDAVEPSGSVKSNGKLLLYPVKTKELMERFYRGLAEYKTWIGYQTEPTAESKATELPSASTSSAYFTVLGDIPYADSGSDDLESNASEEMASDLHGEGNSDDLAGLEEDKESGEEENGEDDGASDS-------------------FSDECG---------SEVM---YCGQCFDEGRNQ-------------TETHKDDRR--IKII-----YHRSFLDKFFSGEKLLNGDASKSY--NCVFCKK------RFSAEELQLHLSEM-HSNP-LTVML........................................ 632
43 -10.900[K] KOG4217 Nuclear receptors of the nerve growth factor-induced protein B type  ali follow..  10  2....................................................PCVQAQYSPSPPGSSYAAQTYSSEYTTEIMNPDYTKLTMDLGSTEITATATTSLPSIST--VEGYSSNYELKPSCVYQMQRPLIKVEEGRAPSYHHHHHHHHHHHHHHQQQHQQPSIPPASSPEDEVLPSTSMYFKQSPPSTPTTPAFPPQAGALWDEALPSAPGCIAPGPLLDPPMKAVPTVAGARFPLFHFKPSPPHPPAPSPAGGHHLGYDPTAAAALSLPLGAAAAAGSQAAALEGHPYGLPLAKRAAPLAFPPLGLTPSPTASSLLGESPSLPSPPSRSSSSGEGT------------------------------------------------------------------------CAVCGDNAAC-----------QHYGVRTCEGC------KGFF----------------------KRTVQKNA------------YVCKNC----------VDKRRRNRCQYCRFQ----KCLSVG........................................................................ 356
44 -10.900[O] KOG2813 Predicted molecular chaperone, contains DnaJ domain  ali follow..  9  2.......................................................................................................................................................................................DKPLLSGSEKTNESERLDSYQYLQRNSSSARNPSFAGAGVVTVEEIRTASAVSSDPPSLYPPVIKTPVSLPIPQAIGYPSASGAGHELQQRQFLDEIEIRELLIDHIGHRCCWGSRPARTWKIHAVEDCNVYVGTLDTFIEEREALTQTVPFTGGEFNGKKHGSEPGLWELDLRPQFPTLFVPYKETQVLVPNSETVEKCTGCTGRGDV----------------------VCPTCN---DGEPGFYKENQMM------KCSTCY---RGLVAHKDGSDTICTNCNGKGKLPCPTCQ---------SRGL------IKCQTCDDRAEGVQLCNTQAYQCTPAYFADSYFLNRFS--SEVISLRAEVPPTANV--VCERHTISVVPVTRVTMEDRGKAFSFYIGFGKEIYLKDYYPARF---CWGLCPCL 414
45 -10.800[TU] KOG3895 Synaptic vesicle protein Synapsin  ali follow..  10  590.KGEGVISTQPTQRPSEEPPAIPTTASSAVRPESSVSVSDSRNTDTLTERAGAGYQPVTNYEQQERVNPFDKEPSKSGSAASIHTSSSSSISSSSISSRINRNGNAIQSPPPPAGPPPPPPTNVTAVGSNANSSSGYRNSFSSSLSKDKTSYGNYGSTTSVETITRMDTNTTNIGATATEAGEASGVTAITNISNSDGIVAPTTGTITTSVTTNDWRSAIGMRSASVSAPAAVTTVLPGDTSGYDSNSIASQGEGLNNPSDLPSYTRPSYSRSESNASKHSDLDVIFGDSKTTPASYGNGKYTRAAGSISDADMIFGGPPSNYKTDRFGASKSMSMTSGGVGSGNGSGSGLGGYKIYDSIQNAAFSDFSDSGSMSSIGSHTKRWSASKEEDD............................................................................................................................................................................................................................ 981
46 -10.700[O] KOG4400 E3 ubiquitin ligase interacting with arginine methyltransferase  ali follow..  16  56..............................................................................................................................................................................................................................................................................................................................................................................................................................RQKKKRSE---YRRLRRINQRNRDKFCFACRQQGHIVQD-----------CPE--KDNVSICFRCGS--KEHSLNACSKKGPLKFAKCFICHEN-----------GHL-CEQNPKGLYPKCCKFCSSV--------------------HKDC-FGHVVGVA..................................... 183
47 -10.700[IG] KOG1340 Prosaposin  ali follow..  12  437..............................................................................................................................................................................................................................................................................................................................................................................................CTLCEYMLHFIQETLATPST--DDEIKHTVENICGQCRNFVEMGDAVIALLVQGLNPRC-TCPLCLFAVEQAQMKIRDNKSLCSHLPNEIKEECVDFVNTYSNELIDMLITDFKPQCVQLKLCPKTPPQLAFDPGFTAAPNCLICIKHILEESCDRCHKVI----DKYGDKIADLLLKEMDPKC-TCVLCEFIMTKLDAD---DVPPKQVCQKCFSVA-CGVCHGVTQAL 871
48 -10.600[K] KOG4216 Steroid hormone nuclear receptor  ali follow..  24  98...............................................................................................................................................................................................................................................................................................................................................................................................................................CKICGDKSSG-----------IHYGVITCEGC------KGFFRQSNATYCPR------KNCL----------IDRTSRN------RCQHCR---------------------------QKCLAVG........................................................................ 162
49 -10.600[R] KOG3253 Predicted alpha/beta hydrolase  ali follow..  9  432.KLPASPSGSEDLSSVSSSPTSSPKTKVTTVTSAQKSSQIGSSQLLKRHVQRTE----VLTHKQAQVPISSEPPEEGEKEDLRVQLKRHHPSSPLPGSKTSKRPKIKVSLISQGDTAGGPCAPSQGSAPEAAGGKPITMTLGQASAGAKELTGLLTTAKSSSSEGGVSASPVPSVVSSSTAPSALHTLQSRLVATSPGSSLPGATSASSLLQGLSFSLQDISSKTSGLPANPSPGPAPQATSVKLPTPMQSLGAITTGTSTIVRTIPVATTLSSLGATPGGKPTAIHQLLTNGGLAKLASSLPGLAQISNQASGLKVPTTITLTLRGQPSRITTLSPMGSGAAPSEESSSQVLPSSSQRLPPA......................................................................................................................................................................................................................................................... 790
50 -10.500[O] COG3058 Uncharacterized protein involved in formate dehydrogenase formation  ali follow..  14  190...........................................................................................................................................................................................................................................................................................................................................................................................................................................................CPVCGSVSSMVQIGTTQGLRYL---------HCNLC------------ETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAI---------AESCDDCGTYLKILYQEKEPKVARMEQEGYAR................................................ 296
51 -10.400[D] KOG3056 Protein required for S-phase initiation or completion  ali follow..  9  98VLNPTIFERRAGSSSIDSSQKVMILGQSKDLGTCRATKKNGDKCTSVVNLTDCDYCIFHVKQEYGKM--------SRRSELQSATAGRGINELRNKVLGKNEVFYGGQTFTAVPARKSAKLITKERDRLSMLAGYDVSPFAHTANHTSKPKTAEPTKIPYAERGGPVSRLAGGVEASRKQRVQDLERLRLLKEENERFEKKKQAEGHVLGSDNKKESEAGTPAVSMPTTPVPDKFKNRGFSFDASLTPKLSGSENFSFEINVGSRQAQNAKLKAAALLKKKPLEKINPNSTRGSESGKRRAIDELNEKFSSSAKRQKIDEDDRELMRKSRIEKIMAATSSHTNLVEMREREAQEEYF---------------------------------------------------------------NKLERKEAMEEKMLTTYKMPCVICQVCKYT------------------AFSASDRCKEQKHPL--KVVDAE-KRF----FQCKDCGNRT-----------------TVFKLPKQSCKNCKGSRWQRTAGRETLSVRGDEETFMGCLAGSANLNLLVPDEE................................ 581
52 -10.300[R] KOG1313 DHHC-type Zn-finger proteins  ali follow..  14  1...........................................................................................................................................................................................................................................................................................................................................................................................................MEDSSQGSFVATINEDYEAICWGCGLNLVLPS----------YAPVFKCGWCGAITNQNPVRPETKSFGLRRFRDRCFVVILAVFMLFVISTLAIS--TFILVAFKCAGKPTNILYGTHPGVGNGALFCNYCPKSPRTHHCRTCGMCV--------------LDMDHH--CPFIGNC---VGAGNHKYFI........................... 168
53 -10.200[T] KOG4846 Nuclear receptor  ali follow..  10  1....................................................................................................................................................................................................................................MSFETKPNYLLLTNPDTPLSVCTSPYYSPSGKTASIPSSEASKPEGTNGQWSHLPTGATYVTDEFSSEFQIQNGSTAAQSGNANNYADPLSHRRYFNNVNGYNHHQFYDTASQASVSSPATSVTSSLSPPDSLSNGHTTQRHHIGKAISF-------------------------------------CKVCGDKASG-----------YHYGVTSCEGC------KGFF----------------------RRSIQRKI------------YRCQVC----------IKRESRNRCQYCRFK----KCLDSG........................................................................ 215
54 -9.980[S] COG4357 Uncharacterized conserved protein  ali follow..  12  40...............................................................................................................................................................................................................................................................................................................................................................................................................................CFECHQELSSHPLEKYDLLDDANKHLIICGVCRHEMTFAEYYDYNSNLICPNCRSPFNPGCK-----------LHYHLYFQ--NPPPAMC........................................................................................................... 116
55 -9.950[P] COG3303 Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit  ali follow..  15  48.............................................................................................................................................................................................................................................................................................................................................................................................SLFNSATAELVYKPLEQPVEPAKPDLKIESVNEKFAEKYP------NQYNSWRSTANGDGENIIYADEE--AKEYNAPRGHFYAVTDVRNILMACWTCKGPDVPRLIAEWGEKDYFN-IGCADCHDT-KDKAEGRPHNNLSFNTAARTEKRAEICANCHVEYYFAGDIKQVTFFEIWSLGMHGK-VTCVDCHMPKVQGADGKVYTDHQDSTCANCHDQ............. 375
56 -9.840[S] COG4306 Uncharacterized protein conserved in bacteria  ali follow..  12  3.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................TYRAAQICTNGHV----ATTAADQKHEL------WEAF------CSHSGEAT-----------------------ILQYPKCSASI---RGDDYVEGVLGFGGDYEPPTF-CNNCGSRFPWAE................................ 82
57 -9.810[O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation  ali follow..  19  846..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KCGVCFDRPKEVVIV-----------KC-----------------YHLFCQQCIQRSLEIKCPGCGTAF----GQNDVRLV......................................................... 897
58 -9.790[O] KOG4275 Predicted E3 ubiquitin ligase  ali follow..  14  3...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................CESCGVEF-----TVFRRK------ACFDC--------------KRYYCANCIAS---RRCKRCSVFAQRPLSRTDLLKLKPKDIFYHISTEGCLE......................................... 76
59 -9.780[DR] KOG1101 Apoptosis inhibitor IAP1 and related BIR domain proteins  ali follow..  11  219..............................................................................................................................................................................................................................................................................................................................................................................................................................ACFACGGKLSNWEPKDDAMHRRHFPNCFKCFCCDGGLRC---WESGDDPWVE--HAKWFPRCEFLIKQTVQSKILTTGENYVNDIVSALLNAEDEKR-----EEKEKQAEE---MASDDLSLI-----KNRMALFQQLTCVLPILDNLLQEERTCKVC---MDKEVSVVFIPCGHLVVCQECAPSL--RKCPICRGII 609
60 -9.590[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  11  4.........................................................................................................................................................................................................................................................................................................................................................................................................................................................FQCDDCGENLKKPRLPRH-----CTAT------SCIDCGNMFGQVSVHY-----HNQCWFCSLCNATMTCEQDYFAHVYGKKHQEKANEVADMDYSK-EHPAVDKNNLTQQPDLDIYVGLSNDYPWFCSLCDINATSEQT............................... 168
61 -9.540[O] KOG4265 Predicted E3 ubiquitin ligase  ali follow..  18  276.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NECVVCLSDLRDTLILPCR---H--C-LCTSCADTL--------------------RYQANNCPICRLFP------GPPADPGGAEEARSP................................................ 335
62 -9.500[T] KOG2290 Rhomboid family proteins  ali follow..  9  1MSEAR-------RDSTSSLQRKKPPWLKLDIPSAVPLTAEEPSFLQPLRRQAFL-RSVSMPAETAHISSPHHELRRPVLQRQTSITQTIRRGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKP--LDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLSAPHTPVTPGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKGRSVRDGTFRRARRRSFTPASFLEEDTTDFPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQADLTGGALDRSELERSHLMLPLERGWRKQKEGAAAPQPKVRLRQEVVSTAGPRRGQRIAVPVRKLFAREKRPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDD--HRPFFTYWLTFVHSLV-----IAPVGFSQHETVDSVLRNRGVYENVKYVQQEN--------------------PSSEALIH-LGAKFSP----CMRQDPQVHSF---REREKHSAC-----------CEECSSTLAV-PIHPSAPELAGHKRQFGSVCHQPRVCDEPSSEDPHEWPEDITKWPICTKN................ 579
63 -9.440[U] KOG4173 Alpha-SNAP protein  ali follow..  13  7..............................................................................................................................................................................................................................................................................................................................................................................................................................LCARLAAGPGAAEPLPVERDPAAGAAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQ------------VADVPEKPRVPAFACQVCCQVFDALDDYEHH---------YHTLHGNVCSFCKRAF------PSGHLLDAHILEWHDS-YQCEGCTEKFKTSRDRKDHMVRMH...................... 169
64 -9.390[KD] COG5189 Putative transcriptional repressor regulating G2/M transition  ali follow..  9  120ISVGSWLRDEIISRRNSIVPASANGAASVSNPPYHRGYSISPQIAYTAYLPNLEKQYCKD-RHYEEAHISTSPNTTNMSQIPMNSAGNTSSSVRMTNNTSSANYNLQNNMAANTKNAGHKTNTMQAHSSNATNNTSINNMHANLQSNMDSNSTIRQSQHPHHQQNIIQQQLQSNSVNHTSGAVPTPSVMGSATASSTTANPNVISITGAPNSGLSMANHSQQLHLNGNLVDAVSTNDVFLRTSNSPSRHVPHNKQINSNNNSGININNNTSHNSNINMGSKNAMVNRPHTFNNYSLNKTSRNPIQHQSRKIDPHQTDLSPLVLVQDIDLSFMDDDILGPSNHNSMNSVVNPTTGSHNYNTFHSSVHAKSSQNMVEDQDIDDIDDDDDVDDDDDDDDDDDTENGSSSNGKSVHNNNYKMPQQAYIDDPARRLYVMDHEEQKPFKC-----PVIG-----------CEKTYKNQ-------------------GLKYHRL-HENPDGTFSVIDPD--GSAKDKPY-----------RCEVCGKRYKNLNG------------KYH................................................. 677
65 -9.350[R] KOG4323 Polycomb-like PHD Zn-finger protein  ali follow..  10  2........................................................................................................................................................................SQKNFFDEGKSYGVNDYAGFHFENGADSSLPQVSAQGVVRETDSSNFDASPVASGSGISDVGPFGADFHQLQQHVQTPYGGMTMPASSSSGATSVPPEQDPSLSVSFNRLPKSASTKTKNGRIRSSRREDDNRIPFYDLDVAEGAEDDLQEDFHVEGMKTKSGRKIQRPVAYNPNATALKRKSRKVDMVT--------------------------------------------------------LCSVCQRGHSPLSNRI-----------VFCDGCNSPY----------HQLC--------------HPPIDDATVQDVDAEWF-----CMKC........................................................................................................... 243
66 -9.350[R] KOG3183 Predicted Zn-finger protein  ali follow..  12  6....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FPDLGKHCSYCKQ------------DFLP--FTCDRCLQVYCLDHRSYMKHD---CPKGNRG--VVICPLCAKGVRLNPDEDPNITWNYEKAVKKKKCIKCRDCSID----------------HCLKHRF----GPDHSCSGP. 140
67 -9.340[O] KOG0802 E3 ubiquitin ligase  ali follow..  18  340................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GALHAALPDATSEELRAYDDECAICREPMAKAK-------RLHC----------------------------------NHLFHLGCLRCPTCRKPLFVGRTEN............................. 413
68 -9.330[S] KOG3726 Uncharacterized conserved protein  ali follow..  12  513........................................................................................................................................................................................................................................................................................................................................................................................................LARLLRKTIGALNTSSETVMESNNMPC-QPVGLDARAYWRAAVPIGLLVCLC----RRVIAAFYFPKREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPR--RCVVCQAPETPESYVCRTLD---CEAVY-------CWSCWDDMRQ----------------------RCPVCTPREELSSSAFSDSNDDT...................... 702
69 -9.330[K] KOG4215 Hepatocyte nuclear factor 4 and similar steroid hormone receptors  ali follow..  24  51...............................................................................................................................................................................................................................................................................................................................................................................................................................CAICGDRATG-----------KHYGASSCDGC------KGFF----------------------RRSVRKNHM-----------YSCRQC----------VDKDKRNQCRYCRLK----KCFRAG........................................................................ 115
70 -9.330[T] KOG3575 FOG: Hormone receptors  ali follow..  15  36...............................................................................................................................................................................................................................................................................................................................................................................................................................CKVCGDRPNN-----------DRYGASACLGC------TVFF----------------------RRAVVKNL------------YKCMNC----------ISCTYRNACRYCRFQ----KCFAVG........................................................................ 100
71 -9.310[B] KOG2084 Predicted histone tail methylase containing SET domain  ali follow..  14  277...................................................................................................................................................................................................................................................................................................................................................................................................................................GDVLLFEEPVAACLEPSYFGT--HCHHC--------FKRLHTPVSCLHC--SGIAFCSQCMGE----------SSYHR--FECEYMDRILQKSLYFGRRKTELYCWPSTACHFVGK--TATRPHRANELNNLKERQRSLRGRYSFSC-SCMACQENLDKQVRFWCTSANCSNLLKFPKDLAKDVRCPRCRKNI 587
72 -9.290[C] COG0348 Polyferredoxin  ali follow..  13  105...............................................................................................................................................................................................................................................................................................................................................................................................................................CAVCPLNIVTD--ASAWLRRKLEIR-LVMILLGSALSGLLLWEW-EHGWCG--------LCGAAYGVIGAKGLFRIKVEHRQQCDNCMDCYN------------------------------VCPEPQVLRDPLHAKK--SESPLVLSKDCISCGRCIDV-----------------CPE................. 273
73 -9.260[U] KOG2066 Vacuolar assembly/sorting protein VPS41  ali follow..  14  575........................................................................................................................................................................................................................................................................................................................................................................................................AEYDQKKLLPFLRKNANYNVNKARKLCSDGYIEETIYLLASGNHYDAVKMMVREYRNMEKVIDYCKDQND---PDLWIHLLGVVAEFPAHFSQEALDKLLVDYTNHAELQQCCYDSTLNDLNVLTQGLISAADESVSVNIVSRCSLCAQIIINSNKKFSDIKVFKCGHIFHLACSLCIACSDQIELIN................................ 806
74 -9.150[O] KOG4628 Predicted E3 ubiquitin ligase  ali follow..  14  49.........................................................................................................................................................................................................................................................................................................................................................................................................................................................FGPNLPSNGLKVYVVPARRPYYGCDS-FVALVAR-GECV--FERKIRVAQNASYSPSVFVGHTTGKALAT---YFTTEVVLIIN--YTK--YDTCVIC----LEDFIEDDKLRVLPCSHPYHTHCIVCPICKRKVFTKGEAR............................. 287
75 -9.120[O] KOG1571 Predicted E3 ubiquitin ligase  ali follow..  23  289..........................................................................................................................................................................................................................................................................................................................................................................................................................................................LCVVCSTNPKEIILLP--------------------CG---------------H----LCEDCAQKISV-----------------------TCPVCRGSIVS................................................................... 331
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhang Y, Stec B, Godzik A. Between order and disorder in protein structures: analysis of "dual personality" fragments in proteins. Structure. 2007 Sep;15(9):1141-7.