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Query: [V] KOG1717 Dual specificity phosphatase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQSTLast
1 -132.000[V] KOG1717 Dual specificity phosphatase  ali  100  1MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST 381
2 -72.000[V] KOG1716 Dual specificity phosphatase  ali follow..  24  3..........................................................................................................................KRERENPCSICGHYHKYEEGEVCGVCGH-------------------------------------CMPVSSDTVAPQQVHVSAFPSEILPFLYLGSYDNASRSELLKTQGISRVLNTVPMCQNLYR--NSFTYHGLDNEK------VLQFDDAIKFLDQCEKDKARVLVHCMSGKSRSPAVVVAYLMKRKGWRLAESHQWVKQRRPSISPGKYLDFGLETYLLFLKLLLIAFSLYTEFYQQLQEFEQGIFGSEMMSAMN 219
3 -43.100[R] COG5350 Predicted protein tyrosine phosphatase  ali follow..  9  1..................................................................................................................................................................................................................MTCIVVSPLSRIA--EMAVKHKAREMVTLIAKEQSFPAVVAAERHLTLAMNDIAFKGTGDLIAPDDAHVLKLWDQSAPLLIHCWMGISRSPAAAIAALSLYPDQDETELAQRLRTVSPYVTPNSRIIAIGDRLLGR................................... 143
4 -20.200[V] KOG1572 Predicted protein tyrosine phosphatase  ali follow..  17  61................................................................................................................................................................................................................MVDNGIFRSGFPDSANFSFLQTLGLRSIIYLCPEPYP-FLKSNGIRLFQFGIEGNKEPFVNIPDHKIRMALK-LDEKNHPVLIHCKRGKHRTG-CLVGCLRKLQKWCLTSIFDEYQR-AKARVSDQRFMEIF......................................... 198
5 -20.200[V] KOG1720 Protein tyrosine phosphatase CDC14  ali follow..  14  215................................................................................................................................................................................................................................LNFFANNNVQLVVRLNSHLKKHFEDIG-IQHLDLIFEDGTCPDL-SIVKNFVGAAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPVVGPQQHW---LYLHQNDF.................................. 336
6 -18.800[A] KOG2386 mRNA capping enzyme, guanylyltransferase (alpha) subunit  ali follow..  15  122.........................................................................................................................................................................................................................SFKQVIHNQRIAGRKLGLVIDLTNT-TRYYSKKEGIKHVKIACKGRDNVSVNAFVNEVNQFVLNLKHSKKYILVHCTHGHNRTGFMIVHYLMRSGPMNVTQALKIFSDARPPGIYKPDYIDALYSFYHEIKPESVICPSTPEWKRSTELDLNGEALPDDEDDDG 292
7 -17.800[A] KOG2634 Initiator tRNA phosphoribosyl-transferase  ali follow..  17  360..............................................................................................................................................................................................................EERLVFWLSSTNLAVGASQVACKETSIDCILNCDQNISVPVSYLEEHLHLPMKGSKFDRFSISRNLPPAVNFAKLKMSSGKKVLVCCQDGAFDGGKSFEEKSITKM--DMRRMLIFICKYAVNARPSRGNLKQVFGFLSSHRENSDE............................ 505
8 -17.500[T] COG2453 Predicted protein-tyrosine phosphatase  ali follow..  23  219................................................................................................................................................................................................................................LDYFVANKVKLIVRLNGPLKKTFENVG-IRHKEMYFEDGTVPEL----SLVKEFIDLTEEEDGVIAVHCKAGLGRTGCLIGAYLIYKHCFTANEVIAYMRIMRPVVGPQQHW---LHINQVHF.................................. 339
9 -15.400[S] COG3453 Uncharacterized protein conserved in bacteria  ali follow..  17  5................................................................................................................................................................................................................QINDEYSVSGQITVDDLDEIKALGFKSIVCHRPD-IAARAQELGLEITHIPVGPMGVTA-----DAVKSMVDALDEFQRPMLGYCRSG-ARSTAVYQQTLHIR...................................................................... 111
10 -14.300[P] COG2897 Rhodanese-related sulfurtransferase  ali follow..  15  8.................VSADWAESNLHA--PKVVFVEVDDTSAYDRDHIAGAIKLDWRTDLQDPVKRDFVDAQQFSKLLSERG-----ANEDTVILYGGNNNWFAAYA--------YFKLYGHE--KVKLLDGGRKKWELDGRPLSSDPVSRPVTSYTASPPDNTIRAFRDEVLAAINVKNLIDVRSPDE-----------------------FSGKILAPAHLPQEQSQRPGHI-AINVPWSRAANEDGTFK---------SDEELAKLYADA------GLDNSKETIAYCRIGERSSHTFVLRELLGHQNVKNYDG.............................................................. 260
11 -13.600[O] COG5533 Ubiquitin C-terminal hydrolase  ali follow..  13  131.IRNVIENYPKFIQLQTIEPGKLSSMLHFHGDALLLIDVRPRSEFVRAHIKCKNIICIDPASFKDTDQQIESVSLITSPHSDITFFSNRDKFKFIILYTDTQLHNNFQQRQTRILAKILSQNS-SGTKILILENGFSNWVKLGGAYQSSVSETAHSPHPPTTLSKLNTPSTIQNKANTVERISPDIRAAQAHAYLPPASNVFSPRIPPLPQQNLSSSRQTILNNSQVLDLDLIVGLENIGNCC-----------YMNCILQ-VGTHDLVRMFLDN-TYLNFINFDSS---------RGSKGLLAKNFAILVNNMHRHGAFTPPNVRTIPVQTI-QFKKICGHINPMYSDSMQQDCQE........................ 548
12 -13.100[V] KOG1529 Mercaptopyruvate sulfurtransferase/thiosulfate sulfurtransferase  ali follow..  14  22.................VSVDWLHSNLGD--ADIKVLDASPIQEYQVAHIPGALFFDLNGIA-----DRKTNLRHMLPSEEAFAAGCSAENNDGVVVYDGMGLFSAAR------VWWMFRVFGHD--KVWVLDGGLPKWRAS-----GYDVESSVSNDAILKASAATEAIEKIYQGQTISPITFQTKFRPHLVLALDQVKENIEDKTYQHID--FDGIAPEPWK---LPSGHIPGSKCVP--FPLMFDSSQTLL---------PAEELKKQFEQE------DISLDSPIAASCGTGVTACILALGLYRLGKTNVAIYDG.............................................................. 300
13 -12.800[R] KOG3636 Uncharacterized conserved protein, contains TBC and Rhodanese domains  ali follow..  12  310.......ADLSQALCLAISVSEILQANQLQGEGVFVVDCRPAEQYNAGHLSTAFHSD-SDLMLQNPSEFAQSVKSLLEAQKQSIESGSIAGGEHLCFMGSGREE------EDMYMNMVLAHFLQKNKEVSIASGGFMALQQ----LADINVDGPENGYGHWIASTSGSRSSINSVDGESPNGSSDRGMKSLVNKMTVALKTKSVNVREKVISFIENTSTPVDRHVSSSDRVGKPYVFSIGDEEEYDTDEIDSSSMSDDDRKEVVNIQTWINKPDVKHHFPCKEVKESGHMFPSHLLVTATHMYCLGLAYIQSRQALNSVVKITSKKK---HP------ELITFK..................................... 642
14 -9.860[T] COG2365 Protein tyrosine/serine phosphatase  ali follow..  17  105.....................................................................................................................................................................................................................LYRSSN-NQADAALLQKLHIKWICDLRSSSEQPTPEIQGVLNKHIPIGTAKNEKTTDGFKEIFSEILTDAKAGLPFVFHCTAGKDRTAALLLTYAITNRYQDLKIAFDEMKKQFGSVD---GYLEKGIGITAE................................... 315
15 -9.580[D] KOG3772 M-phase inducer phosphatase  ali follow..  16  346....FHTVAGKHQDLKYISPEIMASVLNGK-KEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFL------LKKPIVPTDGKRVI--------VVFHCEFSSE------RGPRMCRYVRERDRL--ELYVLKGGYKEFFMKCQSYCE......................................................................................................................................................................................................................................... 481
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 4 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;