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Query: [O] KOG1864 Ubiquitin-specific protease, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGATGSSQLEKEISTTESVNNANEHYYGLVNFGNTCYCNSVIQALFFCRPFREKVLNYKQTLKKSGASKDNLVTCLADLFHSIASQKRRVGTIAPKRFITKLKKENELFDNYMQQDAHEFFNYLINTISETLIQEKIAEREKASRHGTLKKGNVTVNLAPATAGLPRSDEKGTSERNGGITVEGNEFLNKSDTTTWIHEIFQGILTNETRCLSCETVSSKDEDFLDLSIDVEQNTSISHCLRVFSETETLCGDQKYFCETCSSKQEAQKRMRIKKPPQLLALHLKRFKFVEPLNRHTKLSYRVVFPLELRLFNVSDDAEYGDRMYDLVATVVHCGATPNRGHYITLVKSNSFWLVFDDDIVEKLEVSSMEEFSGMSTDANIQMPPGNQSAPQKEFRICLYSVLSGKRLRCLast
1 -131.000[O] KOG1864 Ubiquitin-specific protease  ali  100  1MGATGSSQLEKEISTTESVNNANEHYYGLVNFGNTCYCNSVIQALFFCRPFREKVLNYKQTLKKSGASKDNLVTCLADLFHSIASQKRRVGTIAPKRFITKLKKENELFDNYMQQDAHEFFNYLINTISETLIQEKIAEREKASRHGTLKKGNVTVNLAPATAGLPRSDEKGTSERNGGITVEGNEFLNKSDTTTWIHEIFQGILTNETRCLSCETVSSKDEDFLDLSIDVEQNTSISHCLRVFSETETLCGDQKYFCETCSSKQEAQKRMRIKKPPQLLALHLKRFKFVEPLNRHTKLSYRVVFPLELRLFNVSDDAEYGDRMYDLVATVVHCGATPNRGHYITLVKSNSFWLVFDDDIVEKLEVSSMEEFSGMSTDANIQMPPGNQSAPQKEFRICLYSVLSGKRLRC 410
2 -96.300[O] KOG1871 Ubiquitin-specific protease  ali follow..  20  1....................SISLRPRGLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLSEVKTPTVNAMMSFMTNFSSDLQCDMAFEPTEIYKLWNDSREEHVEGRQEDAEEFLGYVLNKLNDEMLEVIKLIDKPTPQQNGQEPAE-------------PEDGGDVWQMICNNRNKGSVTRQTDFGRTPVSDIFRGELRSRLQR-EGEHSTDVIQPFFTLQLNIEKAASVKEALEILVGRDQLEG---VTGSKTKQEVVAWQQMTLEKLPVVLILHLKYFDYRS--DGCTKILKKVDFPVELKIDAKIKKTSQKQRAYRLFAVVYHDGKEASKGHYITDVFGYSSWLRYDDSSVKPVSEKHVLQPHT-PRVPYLLYYRRSDTLPPQQQQTQQQNGGGSGGV.. 400
3 -85.900[O] COG5533 Ubiquitin C-terminal hydrolase  ali follow..  21  422..PQQNLSSSRQTILNNSQVLDLDLIVGLENIGNCCYMNCILQCLVGTHDLVRMFLDNTYLNFINFDSSRGSKGLLAKNFAILVNNMHRHGPVQTIQFKKICGHINPMYSDSMQQDCQEFCQFLLDGLHEDLNQNGSK---------------------KHLKQLSDEEERMREKMSIRKASALEWERFLLTDFSAIIDLFQGQYASRLQCQVCEHTSTTYQTFSVLSVPVPRVKNILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITRLPKKLIINLKRFDN-----QMNKNNVFVQYPYSLDLTPYWTRGQVPPFRYRLYGVACHSG-SLYGGHYTSYVYKKKGWYFFDDSLYRPITFST----EFITPSAYVLFYERI....................... 804
4 -85.200[O] KOG1868 Ubiquitin C-terminal hydrolase  ali follow..  20  286...........................GFPNLGNTCYMNAVLQSLFAIPSFADDLLTQGVPWEYIPFEALIMTLTQLLALKDFCSTKIKR--ELLGNVKKVISAVAEIFSGNMQNDAHEFLGQCLDQLKEDMEKLNATLNTGKECGD-----------------------------ENSSPQMHVGSAATKVFVCPVVANFEFELQLSLICKACGHAVLKVEPNNYLSINLHQETSIQNSLDLFFKEEELE----YNCQMCKQ-KSCVARHTFSRLSRVLIIHLKRYSFNNAW-LLVKNNEQVYIPKSLSLSSYCNEMGDPLQAYRLISVVSHIGSSPNSGHYISDVYDKQAWFTYNDLCVSEISETKMQE--ARLHSGYIFFYMHNGIFEELLRKAENSRLPSTQA... 905
5 -84.600[O] KOG1872 Ubiquitin-specific protease  ali follow..  16  80..VPATPVKFIEDMNEAEAATAMRLPAGLTNLGNTCYMNATVQCLNAVPELRTALSTFSNDGTDTMSTAFSISSAMKSIFAQM----EKGTTVTPIVLLQALHRASPQFATYRQQDANECWAEILKMLQQKLRPKNQEPSNTV----------------------------------------------QKRHSSFIDQFFGGTFEVKMSSEEDPDSTVTSENFLQLSCFISMDVKMQSGLKSKMKEQLV-----KKSETLGRDAKYIRTYLVSRLPAYLTVQFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPESNNSGYYTLQAVLTHKGRSSSSGHYVAWVRSGDVWFKFDDDEVSAVATDEILRLSGDWHCAYVLLYAPRRLEK................... 474
6 -79.400[O] KOG1867 Ubiquitin-specific protease  ali follow..  20  313..TASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYIS-LCHELHTLFQVMWSG--KWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPA---------------------------------------LIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERCLVTEMLAKFTETEALEG-KIYVCDQCNSKRRAQKQLMICHLPQVLRLHLKRFRWSGR-NNREKIGVHVGFEEILNMEPYCCRERPECFIYDLSAVVMHHGKGFGSGHYTAYCYNGGFWVHCNDSKLSMCTMDEV-----CKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPN. 700
7 -73.700[O] KOG1870 Ubiquitin C-terminal hydrolase  ali follow..  20  276VSRGGSGFSASYNCQEPPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRHVAPSMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKK---------------------------PYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNR--YWRDKLDTVVEFPIRLNMSEFVCNLSARPYVYDLIAVSNHYG-AMGVGHYTAYAKNNGKWYYFDDSNVSLASEDQI-----VTKAAYVLFYQRRDDEFYKTPSLSSSGSSDGGTRP. 945
8 -69.900[O] COG5207 Isopeptidase T  ali follow..  17  341......................KNYGCGLINLGNSCYLNSVIQSLVNGGNWSLDFLGSKFPLDVVYPDNNLKCQWIKLLNAMKCEPELYPNGIKPTTFKKCIGQNHQEFSSNRQQDAMEFLTFLLDLLDKKFFS------------------------------------------------------SSSSGIPNPNDLVRFMMEDRLQCNICGKVKYSYEPTEAIQIPLEENDDMLERIKAYFEGQTIE----FKCANCKEKVTANKKPGFKSLPQTLILNPIRIRLQNWIPV--KTSNELSLPGLIDRDDMLDLGYSTAKPYALTAVICHKGNSVHSGHYVVFIRDKWKWVLYNDEKLVAADSIED-----MKKNGYIYFYTRC....................... 803
9 -67.400[Z] KOG2026 Spindle pole body protein - Sad1p  ali follow..  19  125...SKLDQLQPKHSRTVDGVLYLPGVVGLNNIKANDYCNVVLHALSHVGPLRDYFLQKQSYAHVVRPPGDSLVQRFGELMRKMWNPRNFKSHVSPHEMLQAVLWSSKRFQITEQGDPIDFLSWFLNTLHRALKGNKHPNSS--------------------------------------ILYKIFLGEMKIYTRKMPPVELDDAAKAQLLATEEYKDQVEDKNFIYLTCDLPTDEFRENIIPQVNLYQLLSKFNGTAKEYKTYKANFMKRFEITRLPQFIILYIKRFTKNTFFL--EKNPTIVNFPIKVDFGDILGDKDVKDTKYNLVANIVHDG-DPKKGTYRAHILHNGQWYEMQDLHVTEILPQMI-----TLTESYIQIYERCPNSSFKPQHQLWPKTAGTAHAL. 501
10 -66.700[O] KOG1873 Ubiquitin-specific protease  ali follow..  21  206.GSITSDIKLEGAVTSDIEARDGYVVRGLVNLGNTCFFNSIMQNLLSLDRLRDHFLKENGSGVGGP-----LASSLRKLFTETKPEAGLKSVINPRAFFGSFCSKAPQFRGYDQHDSHELLRCLLDSLSTEESALRKKR---------------------------------------------GVSDNDEKSTTLIESVFGGETSSIVSCMECGHSSKVYEPFLDLSLPVPKAARIHSADESESKGTQDEDEDSEKVITVK--RDATKKVLINKAPPVLTIHLKRFSQDLRGRL-SKLNGHVAFKEVIDLRQYMDSRGEDPPVYRLAGLVEHSG-TMRGGHYVAYVRGSTAWYNVSDAYVRQVSLEKV-----LHSEAYILFYERIFSQE................... 961
11 -63.100[O] KOG1865 Ubiquitin carboxyl-terminal hydrolase  ali follow..  21  56..APVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASQQCLTYIPP------------------------------------------------------------------------------------------------------------------------------------------------------LANYMLSREHSQTCHRHKCCMLCTMEAHITWPLIPGHVIQPSQALAAGFHRGKQEAALEFLMFTVDAMKKACLPGHKQILILVWKRFSDV----TGNKIAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKVEGQWYKMDDAEVTASGITSV-----LSQQAYVLFYIQKSEWERHSESVSRGREPRALGAE. 305
12 -61.300[O] COG5560 Ubiquitin C-terminal hydrolase  ali follow..  20  340..PIEGNHHWPSNYFAYNKLEPASGTTGLVNLGNTCYMNSALQCLVHIPQLRDYFLYDGYEDEINEENPLGYHGYVARAFSDLVQKLFQNAAFPPSMFKSTIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDLNRIIKKEYTEKPS--------------------LSPGDDVNDWNVVKKLADDTWEMHLKRNCSVITDLFVGMYKSTLYCPECQNVSITFDPYNDVTLPLPRTITLDDCLQLFSKPEILGLTDSWYCPTCKEHRQATKQIQLWNTPDILLIHLKRFESQRSF--SDKIDATVNFPITLDLSRYVVYKDDPGLIYDLYAVDNHYG-GLGGGHYTAYVKNDNKWYYFDDSRVTETAPENS-----IAGSAYLLFYIRRHKDGNGLGSSKLQEIIQKSRHG. 1132
13 -57.000[O] COG5077 Ubiquitin carboxyl-terminal hydrolase  ali follow..  22  206...................SKIATGYVGLKNQGATCYMNSLLQSLYIIHAFRRIVYQIPTDSPQGKDS---IAYALQRCFYNLQFMNEP---VSTTELTKSFG---DSLDSFMQHDVQEFNRVLQDNLERSMRD--------------------------------------------------------TKVENALTNLFVGKMKSYIACVNVNFESARSEDYWDIQLNVKGMKNLEDSFRSYIQVETLEGDNCYFADTY-GFQEAKKGVIFESFPPILHLQLKRFEYDFERDMMIKINDRYEFPLEFDAKAFLSPEQSQNCEYVLYGVLVHSG-DLHNGHYYALLKKDGPWYKYDDTRVTRATLREVLEKLKRFMSAYMLLYLRKDKLDE.................. 533
14 -55.000[O] KOG0944 Ubiquitin-specific protease UBP14  ali follow..  14  315......................GPGYTGLVNTGSSCYMNSVLQALVTVDSFQTRYGEQGLETLVNCPLHNDFNAQFSKVVRAMLSGDYSNNHIKPLQFKRVAAGNHRDFSTSKQQDVEEYIRFLFEKIAENSRTEVIDPT----------------------------------------------------------DSFKFKAINRFEDRGTRRVRYTDQEEMLIRLPISGDPSGTPSARGEVDPNLVASIVEMGFSNHQAKYALKQVPTVAEAVEWLFANMDSIPVESA-----AVGLSSDAPEPVTESATQKTFKDGGEKYKLIGMISHMGSRPDSGHYVAHMLKEGKWVLFNDEKVALSQDPP-------KKLAYVYLYKRIA...................... 758
15 -9.500[C] COG1150 Heterodisulfide reductase, subunit C  ali follow..  12  20.............................................................................................................................................................................................EELSELVEPVFEEEEVLSVQACYQCGTCTGSCPSGRRTSY---RTRLIMRKLQLGLVDEVIKSDELWMCTTCYT---------YERCPR-AVKAARNLAAKK....................................................................................................................... 115
16 -9.030[L] COG3677 Transposase and inactivated derivatives  ali follow..  1............................................................................................................................................................................................................MSTHCHCPQCGH-------------------------GNVVKNGFVKDKQRFKCKSCQYQLLYMSGMSMNATAKLLGVSIRDFGEANYEKPAPDSAIVVELDE....................................................................................................... 104

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Godzik A. Fold recognition methods. Methods Biochem Anal. 2003;44:525-46. Review.