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Query: [TA] KOG1902 Putative signal transduction protein involved in RNA splicing, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPRAAPGKQTLPMREMADLDAVHLGLDENEADIAEELQDFEFNTRSEASESNGGDSSDSEPSISSVSTATSSLAGSSKRKTKKPAKQSPQPAVETKSSKSSAKNKAKREPTPEELNGGKKKKRTDSGTKKTTSSEASDKVKSKSPDTEDRQPSAKKSRTKIPSNANDSAGHKSDLSEAEDEKPSLPTLESDSESSDSDSGTQHKRNGGNGGGNGRGKPSSKSSTPEKDSVGGGTHSHSQKGYDYMTKLNYLFRDTRFFLIKSNNSDNVQLSKNKSVWATLPQNDANLNQAFKEARNVLLIFSVNESGKFAGFARMAAPSRRDIPQVAWVLPPSISPKALGGVIELDWICRKELSFNATLHLHNTWNEGKPVKIGRDGQEIEPKIGGELCRLFPEDEQIELTPILKKSKETARVMREKGIHVIYKPPRSLSSRGHGGGGRGGGRGSNHDHLGPMRHKRSYHGAPHHRPYRHHHGMGLPPGGGFKRSGSPYRQMGGAAGAPPGGPGDMAMPSWERYMSSAAAAEAYVADYMRNMHGQLPPLPFVPPFAQLPIPGAGAGAAGALPPGAAAAMYEQLPPPVRYYDGPGAPPLPDYPPPQRPPPPGFDKAPSYEEFAAWKNAGLPTVPPPGFPVYGGAANGGSNGAGGLAAAQAAAAGGGMGAGGGSGGGMGGPGGYRNRDGNNGSAGGRRREYGNRSGGGGSSRDSRPFRERGGGGGQRSYRDNRRLast
1 -151.000[TA] KOG1902 Putative signal transduction protein involved in RNA splicing  ali  100  1MPRAAPGKQTLPMREMADLDAVHLGLDENEADIAEELQDFEFNTRSEASESNGGDSSDSEPSISSVSTATSSLAGSSKRKTKKPAKQSPQPAVETKSSKSSAKNKAKREPTPEELNGGKKKKRTDSGTKKTTSSEASDKVKSKSPDTEDRQPSAKKSRTKIPSNANDSAGHKSDLSEAEDEKPSLPTLESDSESSDSDSGTQHKRNGGNGGGNGRGKPSSKSSTPEKDSVGGGTHSHSQKGYDYMTKLNYLFRDTRFFLIKSNNSDNVQLSKNKSVWATLPQNDANLNQAFKEARNVLLIFSVNESGKFAGFARMAAPSRRDIPQVAWVLPPSISPKALGGVIELDWICRKELSFNATLHLHNTWNEGKPVKIGRDGQEIEPKIGGELCRLFPEDEQIELTPILKKSKETARVMREKGIHVIYKPPRSLSSRGHGGGGRGGGRGSNHDHLGPMRHKRSYHGAPHHRPYRHHHGMGLPPGGGFKRSGSPYRQMGGAAGAPPGGPGDMAMPSWERYMSSAAAAEAYVADYMRNMHGQLPPLPFVPPFAQLPIPGAGAGAAGALPPGAAAAMYEQLPPPVRYYDGPGAPPLPDYPPPQRPPPPGFDKAPSYEEFAAWKNAGLPTVPPPGFPVYGGAANGGSNGAGGLAAAQAAAAGGGMGAGGGSGGGMGGPGGYRNRDGNNGSAGGRRREYGNRSGGGGSSRDSRPFRERGGGGGQRSYRDNRR 722
2 -83.000[R] KOG1901 Uncharacterized high-glucose-regulated protein  ali follow..  16  109..........................................SVATSPTFVPYAIQPEIVSNSSTNSLVETGSANRGRSDGRGSRQRSGTATAGLQRNDPKLPAGNSLGKISEKPRPNSGQSRQSEMDKSDSTSSSGQARQGRVTSVSAQPVDVVSSSRVSSFRQLDIAPPQLNDFSKIATNNNNIRPKLYGGHANIIPDTVREQNRGRRSRALGNQLIVKAYTTKAGNADAEGNIVINPSQYNKEDLRIDYSNAKFFVIKSYSEDDVHKSIKYNVWSSTLHGNKKLQSAYEDAQPIFLFFSVNASGLFCGMAEMTGPVSFDKDMDFW------QQDKWSGSFPVKWHIIKDVPNSYFRHIILQNNENKPVTNSRDTQEIMLKQGLEVLKIFKDHMERTSLLDDFVYYESRQRVMQDERTRLPYRT........................................................................................................................................................................................................................................................................................................ 496
3 -10.700[R] KOG0083 GTPase Rab26/Rab37, small G protein superfamily  ali follow..  11  273.......................................................SGSRKPSISVATPTPLASGSPTRRESLVKPTWQHITPGQLPPKTLDKINGIASDDSDDDGYPKRRPSVIVHQRQQSISQQPLLPEYMTSASIFRDHAPQTSQSQSQSHHLPSGNGFMARLNSVRLASATEQQPLLDSGGGVSATAVARPPVAPAPVAPGPGSEGASATLCKNAGRALIRMISSSKAPEEEDEFDIMGK-IRFFRNKVVVVDG--TRVKLQIWDTA--GQERFRSVYRDAHALLLLYDVTNKTTYDNIR--------------------------------AWL--GEIREYAQEDVVIVLIGNK-ADCSGSERQVKREDGERLGRPFMETSAKTGLNVELSFTAVARQLKSRGYEHGDDGK........................................................................................................................................................................................................................................................................................................ 643
4 -9.720[U] KOG1162 Predicted small molecule transporter  ali follow..  9  13IPE---------KEAFVNYCLLKKQIKKIKTSRKPKPASHYPIGHHSDFGRSLFDPVRKLARTFSDKLFSNSEKPEILQVRRRRGSSETGDDVDEIYQTELVQLFSEEDEVKVFFARLDEELNKVNQFHKPKETEFLERGEILKKQLETLAELKQILSDRKKRNLSGSNSHRSFSSSVRNSDFSAGSPGELSEIQSETSRTDEIIEALERNGVSFINSATRSKTKGGKPKMSLRVDIPDAVAGAEGGIARSIATAMSVLWEELVNNPRSDFTNW---KNIQSAEKKIRSAFVE-RGLGLLYSLNMI----AFTKIMKKFD-------------------------------KVAGQNASSTYLKVVKRSQFISSDKVVRLMDEVESIFTKHFANNDRKKAMKFLKPHQTKDSHMVT.................................................................................................................................................................................................................................................................................................................. 386
5 -9.180[TR] KOG2224 Uncharacterized conserved protein, contains TBC domain  ali follow..  9  188....VPSINVIPHTPIKHENNEIRTENAKDESDKMSQSSLSTSCADEMSDKELSSSEDGDDDCEKPDPGVGLEKILESTQMFDKTPEQFALEHDLMLTDTKSNDSEEQSRGRKKAAGTTSLFSVNLGNGTANYTLSLYGVSGKMRSMRVFYSNTECTSGQLVIATLDSHYKILHFHHGGLDKLAYIFEQWSSIKARSVQEGSPSAIADKQLIICQPAVTKVEKDPEEGLFEKITLNTWRSYENKSGVIIDSGT-----VRKHIFFASMDVEMREKVWESSADQRENIKNDFAGDNNILLNYAV-DINYIQGMSDLLAPL--DEVDSYFCFKNFMQQTVFSSTFVHRWILLREFPENYALHIIVSIYGKDVLTQDLPHDEISLANHMDATLVLQKARGLLFEFTRMEKIPCVLEGLCSAEMEQWNSHKSYRNFYCNQSHIDKESCPYQ................................................................................................................................................................................................................................................................................... 759
6 -9.090[K] COG5164 Transcription elongation factor  ali follow..  9  1MSDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAPTKRRRQERNRFLDIEAEVSDDEDEDEDEEDSELVREGFITHGDDEDDEASAPGARRDDRLHRQLDQDLNKTSEEDAQRLAKELRE-RY-LLPSVDTATI--------WGVR---KKKFNLDRAMGKKKLKILSIFQRDNYTGRIYIEAPKQSVI------------EKFCNGVPDIYISQKLLIPVQELPLLLKPNKSDDVVRIKRD-DQISENNLEVMLKIVPRLDYGKFDEIDPTTQQRKSRRPTFAHRAPPQ.......................................................................................................................................................................................................................................................................................................... 449
7 -8.840[S] COG5373 Predicted membrane protein  ali follow..  9  19............................................................................................................................................GGRRSAERLDREIESLKAEIARLAKEGMGEPGPDLATGRPSEAGVPSVAGTEATADGPWSRAREGAGTSHDESAAGRESGDGAIDGPVAPSAAAARAESLESRIGGRWPVWVGGLALFLVQ-YSIEALTLAAIFGL-IADRFRNAMIPGVLTAAGAVTLFGVVYAAYGIYDFIGLLALVSLATVGLSLLHGQALAGLGLLASLLTPLFVSSGEPRPLFGFLAVAWLATLAASRLRRWSVVPT-AGLGLWGLA.......................................................................................................................................................................................................................................................................................................................................... 307
8 -8.720[R] KOG1093 Predicted protein kinase (contains TBC and RHOD domains)  ali follow..  8  153...................DTLIVLAEEHGCLDIIKELPETVIDLLNKCLTFHPSKRPTPDELMKDKVFSEVSPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINNDYLAERSIEEVYYLWCLAGGDLEKELVNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIREKDTEYQLNRIILFDRLLKAYPYKKNQ-----IWKEARVDIPPLMRGLTWATPIPTDRQIEELLSSPRRVLKAWVVSHPVYWQGLDSLCAPF-NNEALAYACMSAFIPKYLYNFLYAIPWMFTHVFPLHKIFHL--------------DNSSFPFCIGVAILQQLRDR....................................................................................................................................................................................................................................................................................................................................... 598
9 -8.600[U] KOG1092 Ypt/Rab-specific GTPase-activating protein GYP1  ali follow..  10  2................................................ASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLLRRLSWSGIPKPVRPMTWKNVDRRPATLQRKLQPKERILFIWAIRASGYVQGINDLVTPFCNIEADTYWCMSKLLDGIQ---QFAFRWMNNREVPLRCTIRL----RWRKEILEEKDFQEL--------LLFLQNLPTAH................................................................................................................................................................................................................................................................................................................................... 488
10 -8.450[OT] KOG0505 Myosin phosphatase, regulatory subunit  ali follow..  8  620LTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAERTFSRSRAERQAQEQPREKPTDTEGLEGSPEKHEPSAVPATEAGEGQQPWGRSLDEEPICHRLRCPAQPDKPTTPASPSTSRPSLYTSSHLLWTNRFSVPDSESSETTTNTTTAKEMDKNENEEADLDEQSSKRLSIRERRRPKERRRGTGINFWTKDEDETDGSEEVKETWHERLSRLESGGSNPTTSDSYGDRASARARREAREARLATL---------TSRVEEDSNRDYKK-LYESALTENQKLKTKLQEAQLEL----ADIKSKLEKVAQQKQEKTSDRSS--------LEMEKRE-MSEME---MKNLHQLKQIQTLKQMNENRALRLSEDTQEL...................................................................................................................................................................................................................................................................................................................................................... 998
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 3 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.