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Query: [K] KOG2068 MOT2 transcription factor, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSDYGEKTCPLCAEEMDLTDQQLKPCKCGYQICVWCWHHIMDMAEKDQSEGRCPACRTPYDKEKIVGMTVDQERLASEGNMDRKKIQKSKPKSSDGRKPLTSVRVVQRNLVYIVGLPLNLADEDLLQRKEYFGQYGKVLKVSMSRTATGLIQQFPNNTCSVYITYGKEEEAIRCIQSVHGFILDGKALKACFGTTKYCHAWLRNVACNNQDCLYLHEVGSQEDSFTKDEIISAHTRVQQITGATNTMQYRSGSMLPPPLDAYTSDSSTGNPIAKVPSSTSVSAPKSSPPSGSSGKSTALPAAASWGARLTNQHSLATSALSLast
1 -132.000[K] KOG2068 MOT2 transcription factor  ali  100  1MSDYGEKTCPLCAEEMDLTDQQLKPCKCGYQICVWCWHHIMDMAEKDQSEGRCPACRTPYDKEKIVGMTVDQERLASEGNMDRKKIQKSKPKSSDGRKPLTSVRVVQRNLVYIVGLPLNLADEDLLQRKEYFGQYGKVLKVSMSRTATGLIQQFPNNTCSVYITYGKEEEAIRCIQSVHGFILDGKALKACFGTTKYCHAWLRNVACNNQDCLYLHEVGSQEDSFTKDEIISAHTRVQQITGATNTMQYRSGSMLPPPLDAYTSDSSTGNPIAKVPSSTSVSAPKSSPPSGSSGKSTALPAAASWGARLTNQHSLATSALS 321
2 -83.400[K] COG5175 Transcriptional repressor  ali follow..  32  25LSEDEEDYCPLCIEPMDITDKNFFPCPCGYQICQFCYNNIRQNPE---LNGRCPACRRKYDDENVRYVTLSPEELKRKEKERKHREKERKENEYTNRKHLSGTRVIQKNLVYVVGINPPVPYEEVLKSEKYFGQYGKINKIVVNRKTPHSNYHHHSPGYGVYITFGSKDDAARCIAQVDGTYMDGRLIKAAYGTTKYCSSYLRGLPCPNPNCMFLHEPGEEADSFNKRELHNKQQAQQQSGGTAFTRSGIHNNISTSTAGSNTNLLSENFTGTPSPAAMRAQLHHTNAGTPVLTPAPVPAGSNPWGVTQSATPVTSINLSK 361
3 -27.200[A] KOG4207 Predicted splicing factor, SR protein superfamily  ali follow..  14  12..........................................................................................................GMITLKVDNLTYRTSPDSL---RRVFEKYGRVGDVYIPLE-----PHTKAPRGFAFVRFHDRSDAQDAEAAMDGAVLDERELRVRMARYG............................................................................................................................. 93
4 -25.700[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  15  168.....................................................................................SRRAGARDPSSDAYRDSRERDDMCTLKIMQVNENADENSL--REELLFPFAPIPRVSVVRN-----KETGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPK............................................................................................................................. 271
5 -25.700[R] KOG0130 RNA-binding protein RBM8/Tsunagi (RRM superfamily)  ali follow..  10  40...........................................................................SDSNTREAIHSYERVRNEDDDELEPGPQRSVEGWILFVTSIHEEAQEDEI---QEKFCDYGEIKNIHLNLD-----RRTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVK............................................................................................................................. 152
6 -25.700[J] KOG0899 Mitochondrial/chloroplast ribosomal protein S19  ali follow..  15  25......................................................................VYRFQASSMAFCTKLGGHWKQGVNVPVSSMLGSLRYMSTKLYIGGLSPGTDEHSL---KDAFSSFNGVTEARVMTN-----KVTGRSRGYGFVNFISEDSANSAISAMNGQELNGFNISVNVAKDW............................................................................................................................. 142
7 -25.500[J] KOG0122 Translation initiation factor 3, subunit g (eIF-3g)  ali follow..  18  186.................................................................................AAYVPPSMRAGADRSAVGSDMRRRNDENSVRVTNLSEDTREPDL---MELFHPFGAVTRVYVAID-----QKTGVSRGFGFVNFVSREDAQRAINKLNGYGYDNLILRVEWATPR............................................................................................................................. 292
8 -24.800[A] KOG0107 Alternative splicing factor SRp20/9G8 (RRM superfamily)  ali follow..  17  2............................................................................................................SRVYVGNLDPRVTEREL---EDEFRSFGVIRSVWVARR----------PPGYAFLDFEDSRDARDAIREVDGKNGWRVEQSHNRGGGG............................................................................................................................. 76
9 -24.600[R] KOG0114 Predicted RNA-binding protein (RRM superfamily)  ali follow..  15  2...............................................................................................NKRNHIRLPPEVNRLLYVRNLPYKITSDEM---YDIFGKFGAIRQIRVGNT--------PETRGTAFVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYQSN............................................................................................................................. 91
10 -24.300[A] KOG0121 Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily)  ali follow..  14  3.................................................................................ASVELSSYRDQHFKGSRSEQERSLRDSCTLYVGNLSFYTTEEQI---HELFSRCGDVRVIVMGLD-----KYKKTPCGFCFVEYYVRSEAEAAMRFVNGTRLDDRLIRVDWDAGF............................................................................................................................. 109
11 -23.200[R] KOG0226 RNA-binding proteins  ali follow..  14  157..............................................................DKMNFKKQTDPFKKKIKEQQAKKKFVRSGGGQVWEDPSLAEWDENDFRVFCGDLGNEVSDELL---AKAFRKYPSFQKAKVVRE-----SRTNKSKGYGFVSFRDSEDYVRAMREMDGKYVGNRPIKLRKSAWK............................................................................................................................. 282
12 -22.600[A] KOG0108 mRNA cleavage and polyadenylation factor I complex, subunit RNA15  ali follow..  12  1......................................................................................................MSMTAGNVVFVGNIPYDVSEQQM---TEIFNQVGPVKTFKLVLD-----PETGSGKGYGFCEFFDSETTAMAVRKLNNSELGPRKIRVEFPSND............................................................................................................................. 86
13 -22.500[R] KOG0125 Ataxin 2-binding protein (RRM superfamily)  ali follow..  18  83...............................................................................LTQTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDL---RQMFGQFGKILDVEIIFNE-------RGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATAR............................................................................................................................. 189
14 -22.300[R] KOG4454 RNA binding protein (RRM superfamily)  ali follow..  20  11..........................................................................................................EERTIYVANFSEEVDEELL---EELFIQAGPVVKVILRDVR-------DSNAKFALVEFEDELSVLFAIELMNGVRLFNQELQVKPRNGT............................................................................................................................. 90
15 -22.200[A] KOG4209 Splicing factor RNPS1, SR protein superfamily  ali follow..  14  32..............................................................NEIEEEQKKLKAIQNEMVGHMNLNTSSQSNSSQSLLTPEEKAEADAKSVYVGNVDYGATAEEI---EQHFHGCGSVSRVTIQCD-----RFSGHPKGFAYVEFTEKEGMQNAL-AMTDSLLRGRQIKVDPKRTN............................................................................................................................. 156
16 -21.800[A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)  ali follow..  27  4..............................................................................................................VYIGRLPNRASDRDV---EHFFRGYGKLSDVIMKN-------------GFGFVDFQDQRDADDAVHDLNGKELCGERVILEFPRRK............................................................................................................................. 73
17 -21.200[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali follow..  14  2........................................................................NPLTKVKLINELNEREVQLGVADKVSWHSEYK--DSAWIFLGGLPYELTEGDI---ICVFSQYGEIVNINLVRD-----KKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNY............................................................................................................................. 115
18 -21.100[A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily)  ali follow..  17  12..........................................................................................................GDGRIYVGNLPTDVREKDL---EDLFYKYGRIREIELKNR--------HGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTY............................................................................................................................. 90
19 -20.500[A] KOG4206 Spliceosomal protein snRNP-U1A/U2B  ali follow..  18  1...................................................................................................MLTADIPPNQSIYIQNLNERIKKEELKRSYCLFSQFGRILDVVALKT--------PKLRGQAWVTFSEVTAAGHAVRQMQNFPFYDKPMRLQYAKAK............................................................................................................................. 90
20 -20.100[R] KOG4208 Nucleolar RNA-binding protein NIFK  ali follow..  16  1......................................................................................................MAAFSRSAGPILSLNP-QEDAEL---QKEVAQCDTVTRFRLSRK-----KRTGNSKGYAFVEFESEDVAKIVTETMNSYLFGERLLECHFMPPE............................................................................................................................. 85
21 -18.900[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  14  122.QRALAIMCRVYVGSIELGEDTIRQAFAPFGPIKSI--DMSWDSVTMKHKG-------EYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDI---KSVFEAFGKIKSCTLARD-----PTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTP............................................................................................................................. 305
22 -18.900[R] KOG1457 RNA binding protein (contains RRM repeats)  ali follow..  13  91..........................................................................................................GVRTLFVSGLPVDIKPREL---YLLFRPFKGYEGSLIKLT---------ARQPVGFVIFDSRAGAEAAKNALNGIRFDPQTLRLEFAKAN............................................................................................................................. 171
23 -18.800[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  12  15.DAEFPILCQTCLGDVRMIKERFKECKCT-EICQTC--QVRDAALKVADNMPQSDVNKEYYIQNIDAQLQDGDGTEAAGAVGRSLAANEMLSKLARTAPYYKRN--NITTLYVGNLPEEITEPEL---RDQFYQFGEIRSIALVPRQQ------------AFVQYTKRNAAELAAERTNKLVIQGRKVSIKWAHSQAKQGTAAKTDRRFDLAGIPPPSAKPNDYFNLRQEQINVMPAGMKLHQLPSNLVPASAYQMYGQPTYAAPYGNATSTALSSSGVNLDSISIPPPPGQVPYPSQDASRMGAVKK............. 416
24 -18.800[A] KOG0144 RNA-binding protein CUGBP1/BRUNO (RRM superfamily)  ali follow..  28  399..............................................................................................................LFIYHLPQEFGDQDL---LQMFMPFGNVVSAKVFID-----KQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSK............................................................................................................................. 476
25 -18.300[K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif)  ali follow..  10  1...........................................................MQSEESHELTDGISEEKESKETMKSQKADRKKKKLKEKLLKEASKADNRGVCYLSRIPPHMDHVRL---RHILAQYGELGRIYLAPEADTFGGFRGQRFSEGWVEFAKKSVAKRVADMLNGEQIGGKKKSSVYYNIKYLTKF---EEIAYKSAIREQKLNMVLSAAKREKDFYLSKIEKSRAMTEIDARMEKKRKIQEESGSNAEAAPVFPPRAIFQFRQKKSIENETSQSKPGLSTDFLAS.................... 261
26 -18.300[A] KOG1996 mRNA splicing factor  ali follow..  19  262.............................................................STALSVEKTSKRGGKIIVGDATEKGEAQDASKKSDSNPLTEILKCPTKVVLLRNMGAGEVDEDLEVEKEECEKYGKVGKCVIFEIP----GAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACF----------------------------NLDKFRVLDLAE......................................................................................... 403
27 -18.200[A] KOG4212 RNA-binding protein hnRNP-M  ali follow..  18  624...............................................................................EMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKML---KDKFNECGHVLYADIKMEN-------GKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRID................................................................................................................................ 727
28 -18.200[R] KOG0118 FOG: RRM domain  ali follow..  21  146.................................................................................RRKKSFGQGKRRMNARTSMAQREDVIRRTVYVSDLDQQVTEEQL---AGLFVSCGQVVDCRICGDP-------NSVLRFAFIEFTDEEGAMTALN-LSGTMLGFYPVKVLPSKTA............................................................................................................................. 249
29 -18.000[R] KOG0149 Predicted RNA-binding protein SEB4 (RRM superfamily)  ali follow..  19  6..............................................................................VPGSGFHYLNSPFGDTTFTK------------VFVGGLAWETQSETL---RQHFEQYGEILEAVVIAD-----KNTGRSKGYGFVTFRDPEAARRACAD-PTPIIDGRRANCNLASLG............................................................................................................................. 102
30 -18.000[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  11  372........................................................................VAYSKEELVNLIYKTAEKGSRLISAILESADRDIAQRNIFVRGFGWDTTQENL---KTAFESYGEIEECSVVMD-----KDTGRGKGYGFVMFKTRKGAREALKRPEKR-MYNRIVVCNLASEK............................................................................................................................. 486
31 -17.900[K] KOG4210 Nuclear localization sequence binding protein  ali follow..  12  190...........................................................FKNVEQMKAVLELSESHLNGRNMLIKDSENYSGRPDKDDLVAMSKNPPSRILFVGNLSFDVTDDLL---RKHFQHCGDIVKIRMATF-----EDSGKCKGFAFIDFKNEEGSTNELKDKSCRKIAGRPLRMEYGEDR............................................................................................................................. 318
32 -17.900[A] KOG0145 RNA-binding protein ELAV/HU (RRM superfamily)  ali follow..  24  299..............................................................................................................IFVYNLSPDSDESVL---WQLFGPFGAVNNVKVIRD-----FNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK............................................................................................................................. 376
33 -17.800[AJ] KOG0148 Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)  ali follow..  13  2...EDEMPKTLYVGNLSVTEALILQLFSQIGPCKNC--KMIMDTAGNDPYC-------------VEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPQITTEDI---KAAFAPFGRISDARVVKD-----MATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK............................................................................................................................. 174
34 -17.700[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  10  586.APGTEDARTIFVSNLDTTEDEIRQAIEGVA------RFARKANSDLVHRG--------FAYVVMENDQKAQQALLKDRVPVKGRPMFISANDPEKRVGFKFSTTLEKSKVFVRNVHFQATDDEL---KALFSKFGTVTSVRRVTH------KDGKPKGIAFVDFDTEASAQKCVASGDKLMLRERELEVALSNPP-----------------------------VKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRAITNKTPQITARLDAMDVSEGTSTSQPLSNDQ............................. 828
35 -17.700[R] KOG0110 RNA-binding protein (RRM superfamily)  ali follow..  12  312........................................................KQVFFSDFTEKNKVTKASKSGQPLAPAAVDAGNAKWKHQQDSLSKEDDISESGRIFFRNLAYTTTEEDL---RKLFEQFGPVVEVNLPLD-----KLTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLHLLPSKDI............................................................................................................................. 443
36 -17.600[K] KOG0147 Transcriptional coactivator CAPER (RRM superfamily)  ali follow..  12  142LSPEERDARTVFCMQLRIRPRDLEDFFSAVGKVRDV--RIISDRNSRRSKG-------EFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML---RGIFEPFGKIDNIVLMKD-----SDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER............................................................................................................................. 326
37 -17.500[O] KOG0824 Predicted E3 ubiquitin ligase  ali follow..  18  16INSTIDKECAVCYSEM--ILPTTIP-SCGHKFCFICLKGVSVSNNG-----DCPICRGPIDSQIFKKPLQAVDLKMDIPGTPSAAAPDPVVKQEVDDE............................................................................................................................................................................................................................... 105
38 -17.400[A] KOG1190 Polypyrimidine tract-binding protein  ali follow..  16  32.................................................................................SSNSASAANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVI---SLGLPFGKVTNLLMLKGKNQ-----------AFIEMNTEEAANTMVNYYTSVTPRGQPIYIQFSNHK............................................................................................................................. 134
39 -17.400[A] KOG0533 RRM motif-containing protein  ali follow..  20  45...............................................................................RRSGGSGGWKDLDAVQNHGISSRGNDSKVIRVNISNLAPTVISSDL---EELFGDYR-LSSVSVNFN------EHGDSLGTGDISLTK-RDAERLVQKFSGVALDGKIMKFAVIDSS............................................................................................................................. 150
40 -17.300[A] KOG0146 RNA-binding protein ETR-3 (RRM superfamily)  ali follow..  14  5...........................................................MATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDL---KPLFEEFGKIYELTVLKD-----RFTGMHKGCAFLTYCERESALKAQSALHEQKTLPRRLFEAFGNIEECTI-LRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALN 303
41 -17.000[K] KOG1548 Transcription elongation factor TAT-SF1  ali follow..  18  78............................................................................YESTSAEGYPSGSRNKKSKSENSEASPAPVINKAVYIQGLPLDVTVDEI---EEVFKKCGVIAKNIDNGTPRIKRTEDGTPKGDALIVFFRSESVELAEQLFDDTEFRYGSGQK................................................................................................................................... 190
42 -16.600[A] KOG0120 Splicing factor U2AF, large subunit (RRM superfamily)  ali follow..  12  42.........................................................LYWDVPPPGFEHITPMQYKAMQASGQIPASVVPDTPQTAVPVVGSTITRQARRLYVGNIPFGVTEEEMM---EFFNQQMHLVGLAQAAGSPVLACQINLDKNFAFLEFRSIDETTQAM-AFDGINLKGQSLKIRRPHDY............................................................................................................................. 176
43 -16.200[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  11  11.TEKDRVNCPFYFK----------------GACRH------------------DRCSRLHNRPTISPTLLLSNMYQRPDMITPGVDAQGQPLDPRKIQE-----------------HFEDFFEDL---FEELGKFGEIESLNICDNL------ADHMIGNVYVQFKEEDQAAAALQALQGRFYSGRPIIADFSPVT-CRQYEENNCNRGGYCNFMHVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSERQERDGSRGRRQASPKRGGSPGGGREGSEER 277
44 -16.100[DKL] COG5220 Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3  ali follow..  14  1MDDKVDEKCPLCQADRYLNPNMKLLIECYHKMCESC---VDRIFTTGPAQCPTPGCNKILRKAKFREQTFEDAQIEREVDVRKRISRIFNKGQQEFDSLQAYNDYLEEVEILTFNL---IYKIDVEETEEKVKQYEKQNRDSIAANSARAAAEARILAQNEILLKRQKQEAREAAIR................................................................................................................................................ 177
45 -16.000[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  11  78......................................................................RSGGGGGRSGGGGTSFNGAAFTESQLMDEVPKKKFTGRCRLFVGNLPNEVKETEL---KELFSPHGDIAECYLSGK------------GFAFLRLDTRAHAESAKEAIDGRIIHGRQVRVRFAVHG--AIRVKEL----------------SPTVSNEMLYH......................................................................................... 207
46 -15.900[A] KOG0131 Splicing factor 3b, subunit 4  ali follow..  13  18.SAERNQDATVYVGGLDLSEELLWELFVQAGPVVNV---PKDRVTNLHQNYGFIEYRSEEDADYAIKVLNMIKLHGKPIRVNKASQDKKSLDVGAN--------------LFIGNLDPDVDEKLL---YDTFSAFGVIASNPKIMR----DPDTGNSRGFGFISYDSFEASDAAIESMTGQYLSNRQITVSYAYKK............................................................................................................................. 192
47 -15.700[AJ] KOG0123 Polyadenylate-binding protein (RRM superfamily)  ali follow..  11  4.AASSYPMASLYVGDLDVTEAMLYEKFSPAGPVLSI--RVCRDMITRRSLG-------------VNFQ--QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKAL---YDTFSAFGNILSCKVVCDE-------NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYI---KNFGEEVDDESLKE......................................................................................... 209
48 -14.700[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  14  12................................................................SGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELI---PLCEKIGKIYEMRMMMD------FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIP----------------KTKKREEILS......................................................................................... 154
49 -14.600[TR] KOG4019 Calcineurin-mediated signaling pathway inhibitor DSCR1  ali follow..  17  9..........................................................................................................LPSATIACHLDPRVFVDGLCRAESLFRTYDKDITFQYFKSFK------------VRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTL............................................................................................................................. 89
50 -13.900[R] KOG4733 FOG: RRM domain  ali follow..  15  20..........................................................QYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTN--------LYIRGLPPHTTDQDL---VKLCQPYGKIVSTKAILD-----KTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT--NLYISNLP----------------LSMDEQELEN......................................................................................... 159
51 -13.800[R] KOG1995 Conserved Zn-finger protein  ali follow..  16  278..........................................................................................................DNARIYISNLPPDVTTDEL---KDLFGGIGQVGRIKQKRGYKDQTDEKGNYKGDACLAYEDPSAAHSAGGFFNNYEMRGNKISVTMAEKS............................................................................................................................. 372
52 -13.600[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  15  368......................................................................APKESSTSEGADQKMSSPEDDSDTKRLSKEEKGRSSCGRNFWVSGLSSTTRATDL---KNLFSKYGKVVGAKVVTN-----ARSPGARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDGSGEKSKDQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVISVKTSGSKERA........................ 586
53 -13.400[A] KOG4205 RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1  ali follow..  14  2...............................................................TTTVSTGATAVATLRETSPPVDGHEEARLNADSDDGSHGSQDPGK--MFIGGLSWQTTAENL---RDYFGRFGEVNECMVMRD-----PATKRARGFGFITFVD-PSSVDKVLNNREHELDGKKIDPKVAFPK--KVFIGGLSATSTL--YFETYGKVEDAMLMFDKATQRHR..................................................................................... 175
54 -13.400[A] KOG4211 Splicing factor hnRNP-F and related RNA-binding proteins  ali follow..  9  3LGTEGGEGFVVKVRGLSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSG---AFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEI---VQFFSGLEIVPNGITLPV-----DFQGRSTGEAFVQFASQEIAEKALKK-HKERIGHRYIEIFKSSRA............................................................................................................................. 189
55 -13.100[O] KOG3800 Predicted E3 ubiquitin ligase containing RING finger, subunit of transcription/repair factor TFIIH and CDK-activating kinase assembly factor  ali follow..  10  1......KECKKCKSNEYTNQLVMMINECGHPLCKNCVDNIFALNS-----GNCHVCNRVLRKNNFREQIYEDPLIDKETFLRRKLRKIYNLKQDDFENLREFGDYQERKFF-KFPVKIKISNFRRFKNKNFFYEFSIRYSNSPSFSWSNPEFSAQNSKIAPSNSKFQFFRFETVVNLVFETNVNETNAEIQAFEEKHKEQIDRNKRRLDDDQKWIEDQLREERAMKARMTDHMEMDAKEQEAASAVTDTRKIMDELRDSNVAAEVILDRERKKQIEKELEEKEEQEKRKRRNKEMLQTRKRAAENMSFNTVIRVAGRAYVH 315
56 -13.100[O] KOG1571 Predicted E3 ubiquitin ligase  ali follow..  23  283.TLSQDQLCVVCSTN---KEIILLPC--GH-LCEDCAQKISV---------TCPVCRGSIVSKAAAFIA............................................................................................................................................................................................................................................................ 338
57 -13.100[K] KOG2494 C3H1-type Zn-finger protein  ali follow..  10  9IRDTKWLTLEVCRE--------FQ-CSRADADCKF--HPPRVCHVENGLKGRCENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQLMLQNAQMSSLGSFPMTPSIPANPPMAFNPYIPHPGMGL-------AELVPNTPVLIPGNPPLAMPGAVGPKLMRSDKLEVCREFQRGNCTRGENIEASDNTVTICMDYIKGR-CSREKCKYFHPPAHLQARLKAAHHQMNHSAASAMALQPGTLQLIPKRSALEKPNGATPVFNPTVFHCQQALTNLQLPQPAFIPAGPILCMAPASNIVPMMHGATPTTVSAATTPA 338
58 -13.000[O] KOG4265 Predicted E3 ubiquitin ligase  ali follow..  22  271.NSDNSNECVVCLS--DLRDTLILPC-C---LCTSCADTLRYQANN------CPICRLFPGPPADPGGAEEARSPVPRVLQPRPGPE.......................................................................................................................................................................................................................................... 347
59 -13.000[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  16  115........................................................................EELKREQEIRERRNQDRENSRDHNSDNTSSSRF-QTTNLYVVNLSSKVDENFLL---RTFGRFGPIASVKIMWPR--TEEEKRRERHCGFVAFMNRADGEAAKEKMQGIIVYEYELKIGWGKVV............................................................................................................................. 253
60 -12.900[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  15  847...................................................................................GSRGDDSQPSQSELMELIKSIGPRGTVLSCNGFPKDVTLEDVV---EFFNDY-EPDRNSIRIRRGDDGV----MTGECMLACQNQENARRASMDLDGQKLRNSVISVRI................................................................................................................................. 947
61 -12.600[T] COG5432 RING-finger-containing E3 ubiquitin ligase  ali follow..  12  23...DTLLRCHICKDFLKVP------TPCGHTFCSLCIRTHLNNQPN------CPLCLFEFRESLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPTPVP............................................................................................................................................................................................................................... 107
62 -12.600[L] KOG0287 Postreplication repair protein RAD18  ali follow..  12  23...DTLLRCHICKDFLKVP------TPCGHTFCSLCIRTHLNNQPN------CPLCLFEFRESLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPTPVP............................................................................................................................................................................................................................... 107
63 -12.500[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  14  48........................................................EDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATPFRTLFIARINYDTSESKL---RREFEFYGPIKKIVLIHD-----QESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERAR............................................................................................................................. 181
64 -12.200[R] KOG3002 Zn finger protein  ali follow..  25  53....ELLECPVCTNLMYPP---IHQCPNGHTLCSSCKLRVQN---------TCPTCRYELGNIR................................................................................................................................................................................................................................................................. 100
65 -12.200[O] KOG4159 Predicted E3 ubiquitin ligase  ali follow..  12  3..........LFFEPVTT--------PCGHSFCKNCLERCLDHAPY------CPLCKESLKEYLADRRYCVTQLLEELIVKYLPDELSERKKIYDEETAEL----SHLTKNVPIFVCTMAYPTVPCPLHVFEPRYRLMIRRSIQTGTKQFGMCVSDTQNSFA--------DYGCMLQIRNVH-DGRSVVDTVGGKRF............................................................................................................................ 165
66 -12.100[O] KOG0320 Predicted E3 ubiquitin ligase  ali follow..  21  259.QKEELYKCPICMDSVSKREP----TKCGHVFCRECIETAIRATHK------CPICNKKLTARQF................................................................................................................................................................................................................................................................ 314
67 -12.000[O] KOG0823 Predicted E3 ubiquitin ligase  ali follow..  14  109.VPGGFFDCNICLEKAE-------PICCGHLFCWGC---FYQLPLIYLNIKECPVCDGEVTDAEVIPIYGNGDDCDGTKPKLEDCGISLPPRPNAKRVESVRQKIINRG.................................................................................................................................................................................................................... 209
68 -11.800[AR] KOG1365 RNA-binding protein Fusilli, contains RRM domain  ali follow..  9  139......................................................................AILDMDDELLEKTHQFVNIEYQPAPILEDQEVGADGDNVVCRARGLPWQASDHHVA---QFFAGLDIVPGIALCLS------SEGRRNGEVLVQFSSQESRDLALKR-HRNFLLSRYIEVYKAGLD............................................................................................................................. 255
69 -11.600[O] KOG1813 Predicted E3 ubiquitin ligase  ali follow..  13  270.ENALPFACFICREPF--------PVKCKHYFCEHCALKHHTKNKK------CFVCNQPTMGIFNAAHEIKKRMAEERSKAEQGLRRLWPVGEVVPKSK.............................................................................................................................................................................................................................. 357
70 -11.600[O] KOG0826 Predicted E3 ubiquitin ligase involved in peroxisome organization  ali follow..  23  237.SLPQRGECPVCLLSIQTPTA-----VSGYVFCWKCIVSHMKE------HGTCPVTHYPISLDDL................................................................................................................................................................................................................................................................ 291
71 -11.500[R] KOG2135 Proteins containing the RNA recognition motif  ali follow..  12  339.................................................................................APRGRGNIRGRGGFARGGFTGAINRDNCTLQVAKIPPEMNTIAKLN--EHFATFGTVDNIQV---------RYNGEIDSALVTYASKFDAGKAYKSPT-PVLNNRFIKV-----------------------FWHNPGGEGSENATGKPSSPTSPPKPVEKPKIATVQESKFVSVAAQNYRKQIQDAKERLTKEKSILSTLVQAQNQHNIILDKWMVKQKELLIKARTSTDETDKKNATK 543
72 -11.500[O] KOG2231 Predicted E3 ubiquitin ligase  ali follow..  10  41.TGNDDNACVVCFKNVEIFSIG----DCDHPVCYECSTRMRVLCQQNE----CPICRHVLSK--VLFTLDKLPYRELEANNRSDLYSKKYRIGFCTAEIRQQFFKLAPPYRTFEGLRNHVRSEHCVETLNIF-ERRCYTQAELQLHNTKGDPDNRSHRGHPLCEYCNKRDEL-------------RHLRREHYFCHFCHFRAEHFLCEEGKCYKAHVANVHGKSLNKQQAKQTRTLQVEITLGPRGRSGQTEQGITSVRTRNDEHNDYQNDLPSITQRHVSIDAGNEEQFPTLRGASTAPSVSLVRPPPPSMRNLSGTSGL 390
73 -11.400[R] COG3582 Predicted nucleic acid binding protein containing the AN1-type Zn-finger  ali follow..  12  1MSAAIEKECAYC-RQLD-----FLPFHCSF--CNFCSNHRLKEDHHSLLPERASVRIQRVSETREPLRGSNTAKVSSTKKNFGSSSNKIIQLANLKKIAKGDPKIPMQNRIYICYLVDGDETDIAKEDTRYINKVGRAMDYLSIQLNVKSSTLTNSSSNDKFQLCKLKEGKQVSFYNITNEIKDLDTLYLVHNNA.............................................................................................................................. 269
74 -11.300[R] COG5152 Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers  ali follow..  16  247.KEDIPFVCLICKKDYR-------PITCGHHFCEQCAITRYRKTPT------CIQCGADTKGLFSVDKNFDRLLKNRKSKNDEAVKQKVGGFESNNSATTE............................................................................................................................................................................................................................ 336
75 -11.200[R] KOG2789 Putative Zn-finger protein  ali follow..  10  146...ANAMECPICF-----SNFNYTRC-CAQPICSECFVEIRRAEPHISEPAKCPYCMTEKLTPFSFNNNPDTLPSNIAPMGTLSKSSLPLHHIPWPPNQHIKFAHDDKNVVST----------DFIH-PDWQYKLERARRRALRRAANATLLNSHLLETG-----PANANANHNTDLSHDPTSHGGPRRTLSSRRQHYLANVEQLMLAEAIRQSLLDAQSNDSTNSLPSTEVSQPDSTNISNEQEIVQPQPTHTTNVALVEEINRPDSVESAITASSSIDTGNENETQEVNSDSLPQFVHQTMTQTNFQESSPSVAADETR 471
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;