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Query: [G] KOG2178 Predicted sugar kinase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst METLCNPVTGECRVPYDFSPEEKPLLEDKIVSVLGCILSLLNKGRKEILSGRSSSMNSFNLDDVGVAEESLPPLAVFRGEMKRCCESLHIALENYLTPDDERSGIVWRKLQKLKNVCYDAGFPRSDNYPCQTLFANWDPIYSSNTKEDIDSYESEIAFWRGGQVTQEGLKWLIENGFKTIVDLRAEIVKDTFYQTALDDAISLGKITVVQIPIDVRMAPKAEQVELFASIVSDSSKRPIYVHSKEGVWRTSAMVSRWKQYMTRPITKEIPVSEESKRREVSETKLGSNAVVSGKGVPDEQTDKVSEINEVDSRSASSQSKESGRFEGDTSASEFNMVSDPLKSQVPPGNIFSRKEMSKFLKSKSIAPAGYLTNPSKILGTVPTPQFSYTGVTNGNQIVDKDSIRRLAETGNSNGTLLPTSSQSLDFGNGKFSNGNVHASDNTNKSISDNRGNGFSAAPIAVPPSDNLSRAVGSHSVRESQTQRNNSGSSSDSSDDEAGAIEGNMCASATGVVRVQSRKKAEMFLVRTDGVSCTREKVTESSLAFTHPSTQQQMLLWKTTPKTVLLLKKLGQELMEEAKEAASFLYHQENMNVLVEPEVHDVFARIPGFGFVQTFYIQDTSDLHERVDFVACLGGDGVILHASNLFKGAVPPVVSFNLGSLGFLTSHPFEDFRQDLKRVIHGNNTLDGVYITLRMRLRCEIYRKGKAMPGKVFDVLNEIVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPDSAKLELKIPDDARSNAWVSFDGKRRQQLSRGDSVRIYMSQHPLPTVNKSDQTGDWFRSLIRCLNWNERLDQKALLast
1 -237.000[G] KOG2178 Predicted sugar kinase  ali  100  1METLCNPVTGECRVPYDFSPEEKPLLEDKIVSVLGCILSLLNKGRKEILSGRSSSMNSFNLDDVGVAEESLPPLAVFRGEMKRCCESLHIALENYLTPDDERSGIVWRKLQKLKNVCYDAGFPRSDNYPCQTLFANWDPIYSSNTKEDIDSYESEIAFWRGGQVTQEGLKWLIENGFKTIVDLRAEIVKDTFYQTALDDAISLGKITVVQIPIDVRMAPKAEQVELFASIVSDSSKRPIYVHSKEGVWRTSAMVSRWKQYMTRPITKEIPVSEESKRREVSETKLGSNAVVSGKGVPDEQTDKVSEINEVDSRSASSQSKESGRFEGDTSASEFNMVSDPLKSQVPPGNIFSRKEMSKFLKSKSIAPAGYLTNPSKILGTVPTPQFSYTGVTNGNQIVDKDSIRRLAETGNSNGTLLPTSSQSLDFGNGKFSNGNVHASDNTNKSISDNRGNGFSAAPIAVPPSDNLSRAVGSHSVRESQTQRNNSGSSSDSSDDEAGAIEGNMCASATGVVRVQSRKKAEMFLVRTDGVSCTREKVTESSLAFTHPSTQQQMLLWKTTPKTVLLLKKLGQELMEEAKEAASFLYHQENMNVLVEPEVHDVFARIPGFGFVQTFYIQDTSDLHERVDFVACLGGDGVILHASNLFKGAVPPVVSFNLGSLGFLTSHPFEDFRQDLKRVIHGNNTLDGVYITLRMRLRCEIYRKGKAMPGKVFDVLNEIVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPDSAKLELKIPDDARSNAWVSFDGKRRQQLSRGDSVRIYMSQHPLPTVNKSDQTGDWFRSLIRCLNWNERLDQKAL 868
2 -62.300[G] COG0061 Predicted sugar kinase  ali follow..  16  1................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MKFAVSSK-GDQVSDTLKSKIQAYLLDFDMELDENE-----------------------------PEIVISVGGDGTLLYAFHRYSDRKTAFVGVHTGHLGFYADWVPHEIEKLVLAIAKTPYH-----TVEYPLLEVIVTYHENER-EERYLALNECTIKSIEGSLV--ADVEIKGQLFETFRGDGLCLSTPSGSTAYNKALGGAIIHPSIRAIQLAEMASINNRGSPLLLPSHHDCMIKP--RNEVDFQVTIDHLT-LLHKDVKSIRCQVASEKVRFARFRPF--PFWKRVQDSFIGKGE...... 266
3 -37.700[R] KOG4180 Predicted kinase  ali follow..  14  89....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SLAAALYQTQNTQSKRSIGNMEKPSFTPKKVLILSKLTRYEFEKRVEQLATLLKKRGSDY-YLNTLQRELENA-GIESRLVRRFGYTQEAVDWADAVFSAGGDGTFLMASSRVRTKHKPVIGINEGYMCLMRKLPEENLAGALKKLFSGNF-----EWLNRQRIRITVTGDDGI---SDAIELHDQQLNRDPATTRWT-----------------DNPRSPAREIEECMSLSPPVKKRMISEAVEIPEVEKETVELPVLALNEVFIGESLSSRV-SYYEIGINDAQMLKQKSSGITICTGTGSTSWNFNINKLTEQCVQDLMKIVAEHCNLPQIP. 419
4 -22.500[V] KOG1572 Predicted protein tyrosine phosphatase  ali follow..  17  57......................................................................................................................................LNFSMV--------------DNGIFRSGFPDSANFSFLQTLGLRSIIYLCPEPYPESN-----LQFLKSNGIRLFQFGIEGNKEPPDHKIRMALKVLLDEKNHPVLIHCKRGKHRTGCLVGCLRKLQKWCLTSIFD...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 177
5 -19.500[S] COG3453 Uncharacterized protein conserved in bacteria  ali follow..  21  1....................................................................................................................................................MDIRQINDEYSVSGQITVDDLDEIKALGFKSIVCHRPDEAPDQPTFDAIAARAQELGLEITHIPVG-PMGVTADAVKSMVDALDE-FQRPMLGYCRSGA-RSTAVYQQTL.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 108
6 -15.700[V] KOG1720 Protein tyrosine phosphatase CDC14  ali follow..  10  39..........EDAIFYDFGPMNIGHL--RFAVIFHEILNDPENANKAVVANAACMLCCYMILVQAWTPHQVPPFMPFRDAIQDVVYGVWRAKEKGLIDLHSFNLESYEKYEHVEFGDF-----------------NVDFIAFASPQEDHPKGYLATKSSHLNQPFKSVLNFFANNNVQLVVRLNSHLYNKKHFEDI--------GIQHLDLIFEDGTCPDLSIVKNFVGAAETKRGGKIAVHCKAGLGRTGCLIGAH-GFLRFIRPGMVVGPQQHWLYLHQNDFREWKYTTRISLKPSEAIGGLYPLISLEEYRLQKKKLKDDKRVAQNNIEGELRDLTMTPPSNGHGALSARNSSQPSTANNGSNSFKSSAVPQTSPGQPRKGQNGSNTIEDINNNRNPTSHANRKVVIESNNSDDESMQDTNGTSNHYPKVSRKKNDISSASSSRMEDNEPSATNINNAADDTILRQLLPKNRRVTSGRRTTSAAGGIRKISGSIK.................................................................................................................................................................................................................................................................................................................................................................................. 550
7 -14.900[T] COG2453 Predicted protein-tyrosine phosphatase  ali follow..  11  55.....GPLNVSHLIRFAVIVHGI--MGKHRQAKKSKAIVLYSSTDTRLRANAACLLACYMVLVQNWPPHLAPPFLGFRDAIQDCVYGLWRARESSILNIRNIDVHDYETYERVENGDFNWISPKAFASPIQAGWNHASTRPKKLPQP-----------------FAIVLDYFVANKVKLIVRLNGPLYDKKTFENV---------IRHKEMYFEDGTVPELSLVKEFIDLTEEVEED-IAVHCKAGLGRTGCLIGAYRPGMVVGPQQHWLHINQVHFRAYFYEKAMGRAIQQATAAEPLATPPRHPLNATNGTSQSNISTPLPEPTPGQPRKVSGHNPPSARRLPSASSVKFNEKLKNASKQSIQNENKASYSSYEDSEIQNDDETRTVGTPTETISVVRLRRSSSQSNIEPNGVRSPTSSPTGSPIRRTSGNRWSSGSSHSKKSAQRSVSMSSLNNTSNGRVAKPKPSKSRLIS......................................................................................................................................................................................................................................................................................................................................................................................................... 537
8 -10.100[D] COG5279 Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain  ali follow..  9  11................................................................................................................................PFKV-----KARYGWSGQT-----KGDLGFLEG-EVTRIAGSWFYGK-------LRNKKCSGYF--------------------------PH-----NFVILLEERLNS---------------------STENGRQPSKIVESFEKSNKVVIPPVPSRYSDERPRPKKKLSSSMPNSPKKPVDSLTKARKAKSKEMVNEKNIYNTQSSRHHNNSAPNLPLASHSKPQVRNFEESMNNPLPPLPPLPDLDNMRKTDKRAPKKSYSANDLHMARSSREYNYYKDNQKFYDGFIPERYSLEEDSISSGLFSNSQYLNDSACSSENSFALMSDFSATSAGSFARHKYAQSFSDSLQRSQNANGCSTKINDSQEFGDSNASSRNGKMGDILRKIIIPKRNTNIYSSSVSSPKSPKAYPKLPDIQNLNLSATPDEARDWIAVKCHLNRARTLTKYDKHPRYMRALEENRDLILHPQDSIYNGLNTNEVKGNTKPGLVDVELAELNIEYI--DKMTWKRCIRDGTMT---------LDSWAQTTFSARYSTVLEKLFALTDDNGTSDFSAEPQNLEKILYRKHCTPYELTWLFKKLANSLGITCEIVI-RILVNKEFIDVILGNVTNPIHEFVNNRYFLMAPLEMIYTHIPPHIVPSIDQLSALYLPLVFPSFFKNELKLYKFSTALSFLEDSEIYECSLEIPNDVEVFAS................................... 683
9 -9.600[IR] COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase  ali follow..  11  1...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MKRARIIYNPGREIFKKHLAQVLQKFEQAGYETSTHATTCA-----------GDATHAAKEAALREFDLIIAAGGDGTINEVVNGLLDNRPTLGVIPVGTTNDFAGIPREDILKAADTVINGVRPIDIGQVNGQYFINIAGGGRLTELTYDVPSKLKTML---GQLAYYLEVEIEYDGK---LFQGEIMLFLVTLTNSV----GGFEKLAPDFDLMILKKANLAEFNDQHIIYTKANRVKV----NVSEKMQLNLDGEYGGMLP----GEFVNLYRHIHVVMPKEKAEQLDD................. 303
10 -9.330[A] KOG2386 mRNA capping enzyme, guanylyltransferase (alpha) subunit  ali follow..  10  1.................................MVATMDLNASPQPE------EDDEPYVRHLEDYSSRDERIESAVEIARREREERKKRMRYDKPTNSQPVFRDQYYQNRNTKAYDRYKIPQGWLDCPPSGNEIGFLVPSKVPLNESYNNHVPPGSRYSFKQVIHNQRIAGRKLG--LVIDLTNT---TRYYST---TDLKKEGIKHVKIACK-DAVPDNVSVNAFVNEVNQHSKKYILVHCTHGHNRTGFMIVH---YLMRSGPMNVTQALKIFSDARPPGIYKPDYIDALYSFYHEIKPESVICPSTPEWKRSTELDLNGEALPDDEDDDGG-------------------------------------------PAGPVQGFQEESHQVDVKMSNDDVLGDEIPPDQEEGYRQFFYRMLSLNIGVGNFKSENLQLLRQRYYYATWKADGTRYMMLLTTDGCYIVDRSFRFRRVQMRFPFRHPTEGISDKVHHFTLLDGEMIIDTLPDKQKQERRYLIYDMVAINGQSVVERPFYERWKMLEK--------EVIDPRNHEKARSHIYRYDLEPFRVRRKDFWLLSAVEKVLKGFIPS-----------------------------LSHEADGLIFQGWDYVPRTHEGLL--EMNSVDFLYEQDESGRGMLSLFERGKKKHMDGNSVVFR---ELQATNAETATDDSDPAEYSGKIVE-------CSWDQDEKVWVSMRVRVD----STPNDNTFRKVSTI---IPLYILELLWLTIILY..................................................................................... 653
11 -9.050[V] KOG1716 Dual specificity phosphatase  ali follow..  9  2...........................................................................................................RKRERENPCSICGHYHKYEEGEVCGVCGHCMPVSSDTVAPQQVHVSAFPSLYLGSYDNASRSELLKTQGISRVLNTVPM---QNLY---------RNSFTYHGLDNEK--VLQFDDAIKFLDQCEKDKAR-VLVHCMSGKSRSPAVVVAY-YLDFGLETYLLFLKLLLIAFSLYTEFYQQLQEFEQGIFGSEMMSAMNINDAPTFGFGFPKIDNQAQAPVFNNAPTSSIFSSPASSIPPQEFTFGATPPKPTTGGDIAMDGS................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 283
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 4 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;