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Query: [A] KOG2217 U4/U6.U5 snRNP associated protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSSSSGKKHKKDKKNRHRSRSSERPRRVTEDEDVTLDLTDDSSSRHRHHKHKKHKEHRHKHHKQKERERANEVISLEESDSDSSDCVEVPVQAQVQAQAKLRDARESSNRDKERDSGRDRELLRERERERDRERERDRDREKEREREREKERLREREEREREREKERIREREKERLRERERERERERVRELTAPPPPQISKHAEYESRREREIERERDARKRSGRERERERNRERSRSQSPASSSRKPATKEREPSSRSFSPIPENGAGDVLSITETNKLRAKLGLKPLEVDSGPSKAGPPPGSSSQGEIKKPHGEADLSSYKDEWGEFLHKPADNLKEKREAEKLREKLKQRKEKRFLEERLARIKTLGESDEETDNVSKWVDKNKRVVNEREEAMRKAKELEELDEAFGVSEILEQEKTKARQRAYGDSNLKGLRVDHDMDDFGEGRTVILTLKDQDVLNEEEGDTLVNVNMVDEERYKKNVANKKQNPLSYGYNVYEEQYDELGNPIERSVLEKYDDEMEGQPKKRKNFVIGENMDEEREHRRKLLEIKTKLAGKRLETLEDTNLQLASDTYSAEELAKFKKPKKKVKKLRQKLKAEDLAPLAMGEASGSSDFGSRGGRYRDHEDAEMEEFKPQIKVEVEDDDLERVLAKARKLKQKENIIKKPLPVDFESIQREIKPEHVEDTASGVVLTGVDGNIVLNATAEFCRTLGDIPTYGMAGNRNEDSNDMMDFDKTEQPEEHMETHTDEPALSHGTWNSVNPDEVMQPADLDNLGEDLEDRAILDEEPDVGAGVANALRLALSKGYLEKEEKNRPSNTKMAHLQAKNYSIEDKAAGEDEKVGRRDRFHFGPITDFKDKETFKPNVKLDYIDDNGRILNLKEAFRYLSHKFHGKGPGKNKIEKRLKKMEQDGLMKTMSSTDTPLGTLTMLQQKQKETKTAYVVLSGNNKNVPGVSGSAIAKFKLast
1 -149.000[A] KOG2217 U4/U6.U5 snRNP associated protein  ali  100  1MGSSSSGKKHKKDKKNRHRSRSSERPRRVTEDEDVTLDLTDDSSSRHRHHKHKKHKEHRHKHHKQKERERANEVISLEESDSDSSDCVEVPVQAQVQAQAKLRDARESSNRDKERDSGRDRELLRERERERDRERERDRDREKEREREREKERLREREEREREREKERIREREKERLRERERERERERVRELTAPPPPQISKHAEYESRREREIERERDARKRSGRERERERNRERSRSQSPASSSRKPATKEREPSSRSFSPIPENGAGDVLSITETNKLRAKLGLKPLEVDSGPSKAGPPPGSSSQGEIKKPHGEADLSSYKDEWGEFLHKPADNLKEKREAEKLREKLKQRKEKRFLEERLARIKTLGESDEETDNVSKWVDKNKRVVNEREEAMRKAKELEELDEAFGVSEILEQEKTKARQRAYGDSNLKGLRVDHDMDDFGEGRTVILTLKDQDVLNEEEGDTLVNVNMVDEERYKKNVANKKQNPLSYGYNVYEEQYDELGNPIERSVLEKYDDEMEGQPKKRKNFVIGENMDEEREHRRKLLEIKTKLAGKRLETLEDTNLQLASDTYSAEELAKFKKPKKKVKKLRQKLKAEDLAPLAMGEASGSSDFGSRGGRYRDHEDAEMEEFKPQIKVEVEDDDLERVLAKARKLKQKENIIKKPLPVDFESIQREIKPEHVEDTASGVVLTGVDGNIVLNATAEFCRTLGDIPTYGMAGNRNEDSNDMMDFDKTEQPEEHMETHTDEPALSHGTWNSVNPDEVMQPADLDNLGEDLEDRAILDEEPDVGAGVANALRLALSKGYLEKEEKNRPSNTKMAHLQAKNYSIEDKAAGEDEKVGRRDRFHFGPITDFKDKETFKPNVKLDYIDDNGRILNLKEAFRYLSHKFHGKGPGKNKIEKRLKKMEQDGLMKTMSSTDTPLGTLTMLQQKQKETKTAYVVLSGNNKNVPGVSGSAIAKFK 964
2 -24.400[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  14  449...........EEVMSRNRTVSSSAIARAVSDAAAGEYSSAIETLVTAISLIKQSKVAHDERCKILISSLQDTLHGIEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPAPPSSQQN................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 696
3 -22.500[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  10  207..SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKS---PRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR-SPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMSD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 484
4 -19.600[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  14  168IDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKK-RSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPPILGRGNASTNPNPDNGQQSSGDPSWWRQ.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 448
5 -19.000[S] KOG4610 Uncharacterized conserved protein  ali follow..  8  310..RLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 523
6 -18.500[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  11  7......................NADDDGKRVQNEEGNYDPTDHQRQMEDYYKQYEEQRQVANSFHNTTGRPDLVAMQARLAETEQAIHRLNEEKKQPPPGFPIMTTPATQPEISIPRSGENKSSRSPSWAREARRSRSRSRDRRGGRSRSRSPSRRRTSRDRRDDRSSRRRRDRSHSRSRSPPSSANGSSHWSSSNRHSRRRRSRSYSRERDRNSRRDDRRSNLSNNDRYSDWNPGVPSNK................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 225
7 -18.200[Z] KOG3809 Microtubule-binding protein MIP-T3  ali follow..  15  111IGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRE-RDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDA.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 431
8 -18.200[R] KOG2140 Uncharacterized conserved protein  ali follow..  13  652..KVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 908
9 -17.800[K] KOG3794 CBF1-interacting corepressor CIR and related proteins  ali follow..  12  324..SMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRVIGEQVRKSMSLIHRRLYRISGLSSVNAWNLQIREAVNRNDPVESLLLFREMKRGGFEPNN................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 658
10 -17.500[A] KOG2253 U1 snRNP complex, subunit SNU71 and related PWI-motif proteins  ali follow..  14  52..LKLLPLLMNTNEIAIDAAAVAQGAEKELHDDREAKNRPEASKRSRRSRSSSNSSSESDSSSSRSSSYSSRSRSRTPQRSRTSKRRRSNSHASEDSDDAREKRAFKQMMLDKKQAYLARLKRWESRERQMSKRYEREERKEKDRKKTLQKEGKRLKLLEDYDDEKDDPKYYTSSQFFQRKRDYEREREADQKDRMQEQQEIEELKRQIMEEAANDESINIEEEARKRHKLKEEEAMRKMRADSGSPNPHQPLGQSANGEKSSSEEESDSEKTDVKKEIKDEIK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 334
11 -17.000[R] KOG2888 Putative RNA binding protein  ali follow..  14  203..........QKQIEKRIEQYCREQGVTVHQLSTGRSTAGTGGGPGAAGQDADYQDYPEGGVERGSGGRGGGQAGSRSNAYPQPNNYRNDYDERDYYAAASGSSYGRGRGGYEDYPPAPLPPQMPYGERERERDRDRDKNKDYDRHRSKHKKKHNHRQ---SSRSRSRSRSRSRHRSERHERKRDGGGYERSSKSRHNEHYEERERRHR................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 398
12 -16.000[O] KOG0314 Predicted E3 ubiquitin ligase  ali follow..  9  510..EFEAKKTEMKRKRENEIRRSEGGNVVRDSEKSRIMNNSAVTSSPVKPKSRQGPPPPISSDYDRRRRSDRSSPERQSSRRFTSPPRSSSRKSERDRHHDLDSEHDRRRDRPRETDRKHRKRSEKSSSDPTVEIDDNNKSNVFTRISFPEESSGKQR-KTSKSSPAPPESSVAPVSSGRRHHSRREREMVEYDSSDDEDRHFKRKPSRYKRSPSVAPSDAGDEHFRHSKRSKGERARA...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 744
13 -15.800[A] KOG2548 SWAP mRNA splicing regulator  ali follow..  15  671..MELDTASERSHALQPTMSSSSSTGNQTGKYSSATETGSGHPSSGGGGRPNLRERLKRKMQNLLNRQYKADKRAEIEKTERERLQQQEREDEMRELALKLRRRRRELRHKYGTPSSGKLSDSDAESVASESQLAKSSTRRSRSRSESRRRSPPPEQHSRRSSSRTERRRRTRTPSPKYNRRQRSRSRSGSRVERKRRSHSRRRSGSRDRRRSRSRRSQSRRRRQRDRSIERNREREQYRQQHQQQNERLRGRDRDREADYGHGGSGSSNRGRVVISAPPKLKK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 953
14 -15.800[R] KOG3263 Nucleic acid binding protein  ali follow..  16  2.............................................................................................SSSRSGEHRRNYAQGRNYESSRSRGDQRDRDYREYRRNYRDERSSRRYEDSQRRDYSPARRRDRYERHRESVREESPRRPVEHERNWQPELKHGRERFRERDYEGRRDRKERRDGVSPFSPEGEGLERKREHEKLQAPSPKEEEERPVDQGDKMDGVKEDKDGSLEVGKSHDAMTRTKSAEEEIVEQEDEA........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 192
15 -15.200[R] KOG2295 C2H2 Zn-finger protein  ali follow..  9  262.........................KLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 516
16 -15.000[S] KOG4843 Uncharacterized conserved protein  ali follow..  10  248..NAGSYTRDTKFDRENQNYNEQKGEIKMEKEGHAHLAWKEQKDYHRGKRVAEGSTANVDPWVVSRGNPQGPTEVGPKDLSAPVEGSHLEGRETVGENKVDAKNEDRFKEKDKKRKELKHREWDRDKDRNDRRVSVLVGSVMSEPKEIGREERESDRWERERMEQKDRERNKEKDKDHIKREPRTGAEKEISQNEKELGEASAKPSEQEYVAPEQKKQNEPDNCEKDERETKEKRRERDGDSEAERAEKRSRISEKESEDGCLEGEGATEREKDAFNYGVQQRKRALRPRGSPQTTNRDNVRSRSQDNEGVQGNHSFLYPQERIKLHCLENNSKSEVSIVVYKVGECMQELIKLWKE............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 603
17 -14.200[S] KOG2889 Predicted PRP38-like splicing factor  ali follow..  13  164.............................................RLQKRWALEEVDMLPSYKSLLDGDLVAMSDSDSEEEEVTKKEKPRLTSRRRSRSRDRERDVGDRREVREREKLKERRERGDDEPGPSSSGSGRRDDRDDRRRDRDRSRDRDRR-DRRDDDRRDKKKESRRGGADNDEEREIAEANALRAKLGLAPLER......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 320
18 -14.100[T] KOG1882 Transcriptional regulator SNIP1, contains FHA domain  ali follow..  12  2...........................KAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 221
19 -13.900[R] KOG4264 Nucleo-cytoplasmic protein MLN51  ali follow..  10  1MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNEHDLRGQTQEEEVRPKGRQRKLWKDEGREHDKFREDEQAPKSRQERSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPP......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 384
20 -13.700[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  14  732.ASTIPIPQPELKAFVKKEKIDLILPTSRWAREDDETDDEQKKSYSSGSDNAGGITFKTDEEDLKADPSVRVQPENEIDVEQRQKLRHIEIALIEYRESLEEQGMKNSEEIERKVAIHRKRLEADGLSGNQRVLPEKREKREDSRDSSRKRNRSESQNRSQSPPQKSLTRERVRDHDLDKDRHRDRDRQQHDLDKDRKRRAKSSSRERDHDRSRERDRDWRRRGMR.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 957
21 -13.100[P] KOG4505 Na+/H+ antiporter  ali follow..  8  435....MLGKRINTLALSFTRTRDSHFAFNLPRVRQGQSLPIKRVDALRSSANSIASSIRRRHPVNIQEDEDADISTVSLPEAAHLREERAESPRGGHYDAEEFPSEDYESRQPRRSNEEDREEEMNPGDETYLIGEDLVVEDSQGNIISHTSSRDANGPSIDEKLAQGDPKAKSFGRKFRSFLRRSYDTFQRNLHEPDDERQREPTLGHIESSIENHRPRYSRQNSESHLRENSVERRRREQVLTNIGDSESEDDNIPRPGIVPFYNENNESSSDTRNGLLSDNVSESRSRRPSRAPSAAVSSEGSPVEEDNEAQHRPNIRFLELTRAWE........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 759
22 -13.000[S] KOG2812 Uncharacterized conserved protein  ali follow..  10  16..GSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLAHQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKK-STTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSD............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 289
23 -12.900[S] KOG3869 Uncharacterized conserved protein  ali follow..  15  199..KNKKNKKSKKSKKKKKNRRSSNEESSDSESNDSDDDLDRKLARQVSKLKGDQGDLKLDKLLDAKYRTISNQLDMATKKKKSKKSKKKKSSDSSDESSDEEEEPRRKHKRSHSSEDRNQRERRRSRSPRDRKKRQSRSPEQRQRQRSPEERRERRRSRSRSPLARRQRRTRSPEDRKARRQSKDTSKQREKRRSRTPEERSRSKRSRSRSSKGDDKRRIAERPPPSRPTGKPKLSEADREARLREMMDNATWREADRSQVVRKHREAYAREEAQNRERD............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 476
24 -12.500[K] KOG2821 RNA polymerase II transcription elongation factor Elongin/SIII, subunit elongin A  ali follow..  10  78.....VERNAEPDEQDFEKSNSRKRPRDALQKEEEMEGDYQETWKATGSRSYSPDHRQKKHRKLSELERPHKVSHGHERRDERKRCHRMSPTYSSDPESSDYGHVQSPPSCTSPHQMYVDHYRSLEEDQEPIVSHQKPGKGHSNAFQDRLGASQERHLGEPHGKGVVSQNKEHKSSHKDKRPVDAKSDEKASVVSREKSHKALSKEENRRPPSGDNAREKPPSSGVKKEKDREGSSLKKKCLPPSEAASDNHLKKPKHRDPEKAKLDKSKQGLDSFDTGKGAGDLLPKVKEKGSNNLKTPEGKVKTNLDRKSLGSLPKVEETDMEDEFEQPTMSFESYLSYDQPRKKKKKIVKTSATALGDKGLKKNDSKSTGKNLDS.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 450
25 -12.000[T] KOG2370 Cactin  ali follow..  8  3.........................................................................................KDSKKHKKERRRERSPSTSDSDEERLQKRLAEQRSLKKDEKRRQKEEMKKNESAEEKRARRMEKKMRKDAKRKDADAEDTLIPPELNYTNLNNPNDTKLTQTFVWGKKLEREGKSGLTQDEITKQTSQRIRKNLHEAAEFKRIRDSRAAAKEDMEMMKRDADLRAGQISDTKEREFQMDQIKERTRIRIDQGRAK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 198
26 -11.600[R] KOG2891 Surface glycoprotein  ali follow..  9  261.DKQKHLSDSNIQRRERIRKKFIAKAKAEDEEREKLKKQQEEELDRERQKQEELKKAEAEKQREREERRKEKHMKKIQERGQVEISQKIRIEERKLMIAQRKLESIRTLEKLFERIQLKQRDKNRRVKQDDDKDIQRGRLVEKYKAATEKLVCDQRKIVQEIKSNTPLLGLLKSKSKKSAVPVDASSEDEAAASKRHKMGNGVTESAPPGDVNSALNPLNAVAAM................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 484
27 -11.100[S] KOG4051 Uncharacterized conserved protein  ali follow..  9  157..NEKDSTIPKESPSTDLKNDNNKQEKNATIKVKELPEYHTEENDSPIDVQKEPIKEVQSDEKELQREHMSEEEQKMKSTNKTAAPVRKSQRLKRSKEVKFEDEEKEEIEEDNTKDEEQKEKKEEIQEPKITHNEEVDKEKNENEEGDDEREKSTSYENTNGSESEGVDEGVDEELGYESEREAEGKGKQIESEGGNLKKKTENKKGDDQQDDTKKDSKDKNEPLAKRTRHSSSTGNTSNETSPKRKRRKAGSRKNSPPATRVSSRLRNKK..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 425
28 -11.100[K] KOG2478 Putative RNA polymerase II regulator  ali follow..  9  333.....SKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 531
29 -11.100[A] KOG2412 Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor  ali follow..  9  10.NSDTDSPEFEETCSTTSSTSSQCPTPEPSPAIKLPSFTKVGTKKLVNESVVILDPALENALRDLNLQSKLIPINEPIVAASSIIVPHSTNMPLPRASHSSLLDNAKNSNATAPLLEAIEESFQRKMQNLVLANQKEIQSIRENKRRVEEQRKRKEEEERKRKEAEEKAKREQELLRQKKDEEERKRKEAEAKLAQQKQEEERKKIEEQNEKERQLKKEHEAKLLQQKDKLGKAVTNFDKISKMFWHYKDKIAQIKQDIVLPIKKADVNVRNLLSRHKRKINPKFGQ..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 295
30 -11.000[J] KOG2147 Nucleolar protein involved in 40S ribosome biogenesis  ali follow..  10  28......GRKKGAQVGAPTASRKRAHEQREQTLGVEYDRKNKISKIVDKRLGEKDGKSEEEKGAMRFTEERVKNYKRASKFNLTDDGDEEEEVLTHKGKALSDIEKYDKSMISDSDDDEEPGNLGSNMVKVAHFGGGEKTAEEHVREKISREDMISNLIAKTKLARHEKQQQKDELELMTESLDSKYQALMGKMKASFRPTGRQPLEKDDYDKLTITLKTEADARATPADRKLSEEEEALKEKERLETLEAAPDADVDIDAGSKADARKVQAKNSRFEVKFDDEGGLIDEDTVEKSRILKKNLDGSDESDDDEDLEDEEEDLDDLLEDEDELEEDSDDEEAQEAQKVVKKAKKSAPEPAET............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 381
31 -10.800[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  11  480............EKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDGSGEKSKDQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREKRSVVSFDKVKEPRKSRDSESHSRVRERSEREQRMQAQWEREERERLEIARERLAFQRQRLERERMERERLERERMHVEHERRREQERIHREREELRRQQELRYEQERRPAVRRPYDLDRRDDAYWPEAKRAGLDERYHSDFNRQER.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 745
32 -10.800[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  12  155.......................................................RQYEENNCNRGGYCNFMHVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSERQERDGSRGRRQASPKRGGSPGGGREGSEERRARIEQWNREREEKEEGGA............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 296
33 -10.500[K] COG5164 Transcription elongation factor  ali follow..  11  1MSDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAPTKRRRQERNDIEAEVSDDEDEDEDEEDSELVREGFITHGDDEDDEASAPGARRDDRLHRQLDQDLNKTSEEDAQRLAKELRERYGRSSSKQYRAAAQDGYVPQRF.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 277
34 -10.500[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali follow..  11  113.............SNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAEQPSSSSPRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTRIRDRGRLQMHILAGIMGVLKGVVIEVEVGAEINPIGIKGPDAPGRGVLRIPVTVGVTEDFSCTVDLE........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 332
35 -10.300[A] KOG0796 Spliceosome subunit  ali follow..  23  259................................................................SDRRLADHFGGKLHLGYMLIRDKLAELQEEKNKVHKERVEERRSKERSRERESSKDRDGGDNRDRGRDVDRRSRDRDRHHDHREHDRNYNQSRGYDSRSRRSSRSRSRERPRDHDRRRRHDR.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 380
36 -9.850[DZ] KOG2229 Protein required for actin cytoskeleton organization and cell cycle progression  ali follow..  10  503.GKNAAMEVQEAKKGGKDSKRPQFGADNSVQGIAGIELLAKWKKEHGEESENEDADANWEVDVDSEEDDVDGEWVTMDSDKEYDVDMEDSDDEKDNAKGKESDSDLELSDDDDEKEVKDEQEDADIDPEAAFREIASTRILTPADFAKLQELRNEESVAKIMGIHKQDKREELVDASTLTGPIKYKQSREERLQKVLEGREGRDKFGSRRGKRDNMRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLRAHITKQKKKG........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 766
37 -9.830[U] KOG0946 ER-Golgi vesicle-tethering protein p115  ali follow..  8  630.................................................................................................................KSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGRLREEIEELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLVLLADQDQKILSLKNKLKDLGHPVEEEDELESGDQEDEDDESEDPGKDLDHI...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 962
38 -9.700[S] KOG3683 Uncharacterized conserved protein  ali follow..  8  208..SKEASRQALMDNGNNLEAALNVLLTSNKQKPVMGPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSFAEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQNPVRSNS........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 489
39 -9.460[S] KOG2465 Uncharacterized conserved protein  ali follow..  11  465..TGCNCFGGKKCKKRWASAKNTDTPEMSEVYCPSCEDPSNESPACLAKMPDKRPTRLKPKSSILSVESELLVGKRSSFRLPSEIKRKQQGGSITRSASLSAADRRTSLPVATKRIIPPRLRTAKAKDLEKDKEKEKDKNKENDKKSSNQKVNGSATNFLAKMSPKRLKAGKEKDKDKDGNKEKEKDKFKAMDAAKKKAVNNNNPKPDISKSEEYEIADDATSLNGSESEPVGAAKMVILSESDSKLMISVRGREELPVVDSPKTPPKRFEKCVSLPVEPESHLLQPDENNENEQSDITNVISPTELTPMLDVANGNGEAN................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 783
40 -9.340[R] KOG4520 Predicted coiled-coil protein  ali follow..  9  53..KGRAPCAGPSREEELAAVREAEREALLAALGYKNVKKQPTGLSKEDFAEVCKREGGDPEEKGVDRLLGLGSASGSVGRVAMSREDKEAAKLGLSVFTHHRVESGGPGTSAASARRKPRAEDQTESSCESHRKSKKEKKKKKKRKHKKEKKKKDKEH-RRPAEATSSPTSPERPRHHHHDSDSNSPCCKRRKRGHSGDRRSPSRRWHDRGSEA.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 263
41 -9.190[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  11  10......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RGKDSEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEEDNEEEESTDGEEVEDEEKDSKSKQTDDKPSGSGAASKKALTAELPKRDSSKPEYQDSDTSDEEDIRNTVGNIPMHWYDE----------YKHIGYDWDAK--------KIIKPPQGDQIDEFLRKIEDP----DFWRTVKDPLTGQDVRLT.................. 223
42 -9.170[S] COG5604 Uncharacterized conserved protein  ali follow..  11  4LSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGKIVLTSDTIQQWQKLLETNHSLTTLQK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 200
43 -9.170[J] KOG2256 Predicted protein involved in nuclear export of pre-ribosomes  ali follow..  11  4LSSIIKARKANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQKQLEGLKEKDPEFYKFLEQNDQDLLEFNAAETDAMAKEIDENERLKSSSGKIVLTSDTIQQWQKLLETNHSLTTLQK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 200
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.