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Query: [S] KOG2236 Uncharacterized conserved protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSDDLFSKALENPDQDLNVELPKDDVDLGLLGDGGNERKTDEPVADAERSTGLGSGSSESESDSGSDSDSDSGSSGSEDDSADQDVEGEDEGGDAIENEDEDEDPSPSGPILSKNEILEETVPELPEDYEISEKTIITPIGVLKSAFENNIIIHATMSGEKRVLKEGSIFCLEDRTLIGMLTEVFGPLQNPFYRIKLPDSKKNLFDELKVRLGEKAFIVTPDAHWIDTFELKRNKGTDASNGYDEELPEEEQEFSDDEKEALFKKMKKQQRQRKKRDNRKLANDSDNVKVKRARQPKANSLPKLVPPLGMSSNAPMQHGYKSRNARENIKRESSATSNRNGSSPVPITQHHQQQFSANNYPFPQQPNGMPYPPYSPFPQPTNFQYPPPPFGQATPAQFSNTVPYGSLPPAYNNMSPPTQQSFMPMTQSQPPLPYGVPPMNQMQNPMYIQPPPQAPPQGNGNFQQVMELHQILLQQQQQQHQYQHQHQQDPRTLast
1 -90.600[S] KOG2236 Uncharacterized conserved protein  ali  100  1MSDDLFSKALENPDQDLNVELPKDDVDLGLLGDGGNERKTDEPVADAERSTGLGSGSSESESDSGSDSDSDSGSSGSEDDSADQDVEGEDEGGDAIENEDEDEDPSPSGPILSKNEILEETVPELPEDYEISEKTIITPIGVLKSAFENNIIIHATMSGEKRVLKEGSIFCLEDRTLIGMLTEVFGPLQNPFYRIKLPDSKKNLFDELKVRLGEKAFIVTPDAHWIDTFELKRNKGTDASNGYDEELPEEEQEFSDDEKEALFKKMKKQQRQRKKRDNRKLANDSDNVKVKRARQPKANSLPKLVPPLGMSSNAPMQHGYKSRNARENIKRESSATSNRNGSSPVPITQHHQQQFSANNYPFPQQPNGMPYPPYSPFPQPTNFQYPPPPFGQATPAQFSNTVPYGSLPPAYNNMSPPTQQSFMPMTQSQPPLPYGVPPMNQMQNPMYIQPPPQAPPQGNGNFQQVMELHQILLQQQQQQHQYQHQHQQDPRT 492
2 -37.400[J] KOG3262 H/ACA small nucleolar RNP component GAR1  ali follow..  9  2...........................................................................................SFRGGNRGGRGGFRGGFRGGRTGSARSFQQGP----------PDTVLEMGAFLHPCEGDIVCRSINT---KIPYFNAPIYLENKTQVGKVDEILGPLNEVFFTIKCGDG----VQATSFKEGDKFYIAADIERFLPKPKVVGPPKPKNKKKRSGAPGGRGGASMGRGGSRGGFRGGRGGSSFRGGRGGSSFRGGSRGGSFRGGSRGGSRGGFRGGRR........................................................................................................................................................................................ 205
3 -26.900[J] COG3277 RNA-binding protein involved in rRNA processing  ali follow..  14  2......................................................................................................................................SRLRTLGRVKHMSKTGMLVVTLN--PAYIPKIGDKVVTRRMEHIGFVADVIGPVSSPYALVKPKNLDKI--------IFEELYVVKEYGGGRKGKGKGSREGSRKKGNRKGR...................................................................................................................................................................................................................................................... 103
4 -10.400[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  11  1MTKKLALKRRGKDSEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEEDNEEEESTDGEEVEDEEKDSKSKQTDD-PEYQDSDTSDEEDIRNTVGNI-------------------PMH-----WYDEYKHIG--YDWDAKIIKP---PQGDQIDEFLRKIEDPDFWRTVKDPLTGQDVRLTDEIKRIVSGRIPNKDHEEYEPWIEWFTSEVEKMPIKNVPDHKRS............................................................................................................................................................................................................................ 271
5 -9.610[S] COG5373 Predicted membrane protein  ali follow..  8  1MLEAIALLAFVMALAAFLGGRRSAERLDREIESLKAEIARLAKEGMGEPGPDLATGRPSEAGVPSVAGTEATADGPWSRAREGAGTSHDESAAGRESGDGAIDGPVAPSAAAARAESLESRI----------GGRWPVWVGGLALALGGYFLVQ--------SIEAG-LLSPAVRLTLAAI---FG-IRRRDVPAIADRFRNAMIPGVLTAAGAVTLFGVVYAAYGIYD-LVSLATVGLSLLHGQALA.................................................................................................................................................................................................................................................... 246
6 -9.490[R] KOG4264 Nucleo-cytoplasmic protein MLN51  ali follow..  15  1MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGLHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQE-----------------NKVGKKGPKHLDDD-----EDRK-------------NPAYIPR---------------KGL--FFEHDLRG---KGRQRKLWKDEGRWEHDEQAPKSRQEYDSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRT........................................................................................................................................................................................... 295
7 -8.750[TG] COG5037 Gluconate transport-inducing protein  ali follow..  13  1..................................................................................................................................MTEPGNLQPTGFIGTTVDALLLFEAC---------------------QNYT---------HFVDRRPQDRERERL----IRSGS-VF--------VFDEVQSGIK-TDGIAWSPSRVIGNFLVYRQLCKKNSVSDRKRSSKSRSDSDEEEVSAFTVS............................................................................................................................................................................................................. 118
8 -8.750[TG] KOG4476 Gluconate transport-inducing protein  ali follow..  13  1..................................................................................................................................MTEPGNLQPTGFIGTTVDALLLFEAC---------------------QNYT---------HFVDRRPQDRERERL----IRSGS-VF--------VFDEVQSGIK-TDGIAWSPSRVIGNFLVYRQLCKKNSVSDRKRSSKSRSDSDEEEVSAFTVS............................................................................................................................................................................................................. 118
9 -8.110[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  12  1MSGARRDNRRSNGRDDSSRVAKAENDRKPGRENRGGDEKRGNSNNAARSGGGGGGNRGGAERGIAAQQPYDNNGGHRSGGGGGRSGGGGTSFNGAAFTESQLMDEVPKKKFTGRCRLFVGNLPNEVKETELKE---FSPHGDIAEC--AFLRLDTRAHAESAKIDHGAAIRVKENEMLYHAFSHFGDVERAVHIVEFERKPNCNEAMAAIR--DKVFLLTASPKPLICEVLEPRDEDDGGLSKERELGPR-EELRESRRRLESDMELAYQDYQAQMLREDLQRRQQELERLEAARRERMRG............................................................................................................................................................................................... 377
10 -7.980[R] COG1480 Predicted membrane-associated HD superfamily hydrolase  ali follow..  13  482...................................................................................................................ELSNPNHPLLRKILTETP-------GTYHH----SVMVANLSEAACEAVGANGLLA------VGAYYHDLGKTKRPQYFIKLSPQLSKNIIISHTTDGANMLRSYKFPKELV-DIAEQHHGTYKAKEKGDQITEEEFRYPGDSVEAAVRSMHNPNPERIEK........................................................................................................................................................................................................................ 657
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.