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Query: [C] KOG2415 Electron transfer flavoprotein ubiquinone oxidoreductase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLVPLAKLSCLAYQCFHALKIKKNYLPLCAIRWSSTSTVPRITTHYTIYPRDKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAVRLKQLAVAHEKDIRVCLVEKAAQIGAHTLSGACLDPGAFKELFPDWKEKGAPLNTPVTEDRFGILTEKYRIPVPILPGLPMNNHGNYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLFHDDGSVKGIATNDVGIQKDGAPKATFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRANCEPQTYGIGLKELWVIDEKNWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVALGLVVGLDYQNPYLSPFREFQRWKHHPSIRPTLEGGKRIAYGARALNEGGFQSIPKLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGILAAESIFNQLTSENLQSKTIGLHVTEYEDNLKNSWVWKELYSVRNIRPSCHGVLGVYGGMIYTGIFYWILRGMEPWTLKHKGSDFERLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLRDDSIPVNRNLSIYDGPEQRFCPAGVYEFVPVEQGDGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGMLast
1 -139.000[C] KOG2415 Electron transfer flavoprotein ubiquinone oxidoreductase  ali  100  1MLVPLAKLSCLAYQCFHALKIKKNYLPLCAIRWSSTSTVPRITTHYTIYPRDKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAVRLKQLAVAHEKDIRVCLVEKAAQIGAHTLSGACLDPGAFKELFPDWKEKGAPLNTPVTEDRFGILTEKYRIPVPILPGLPMNNHGNYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLFHDDGSVKGIATNDVGIQKDGAPKATFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRANCEPQTYGIGLKELWVIDEKNWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVALGLVVGLDYQNPYLSPFREFQRWKHHPSIRPTLEGGKRIAYGARALNEGGFQSIPKLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGILAAESIFNQLTSENLQSKTIGLHVTEYEDNLKNSWVWKELYSVRNIRPSCHGVLGVYGGMIYTGIFYWILRGMEPWTLKHKGSDFERLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLRDDSIPVNRNLSIYDGPEQRFCPAGVYEFVPVEQGDGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM 617
2 -55.900[C] COG0644 Dehydrogenases (flavoproteins)  ali follow..  16  1................................................................MTEQYDVVVAGAGTAGAYASYLLAK------AGLKVALLESKSGDQIVKTCGDGLGLHHVERMSKYLTPNPKVFQNKI--EGVELISPDQKTTL-------IVRGEGYVLDRFAWGKWLVEEAVRAGAVLYEGHTATAPIV-ENGSVVGVKAVE----------RISGVAKEFRARVVIDSTGSAAVLRSKLIGWL-VSEPLHPEDVSHAYREIIYSEEPLENPQYIKIYLDMVVAPG--GYWWIFPRNATMLNVGLGIW-----GILKQNPRINYEKF-----ILPKFKVRGKYHIGGGFIPTRR--PLKSLVGNGIVALGDAAAAVNPIHGGGIGQALLTAELSSKVITKAFEKGDFSEKTLWEYNVLYMREWGYRQAQLDVLRLMLQT.................................................................................................................................................................. 351
3 -48.500[I] KOG1298 Squalene monooxygenase  ali follow..  12  19.........................................TVFYLTNMKKKATDLADTVAEDQKDGAADVIIVGAGVGGSALAYALAK------DGRRVHVIERDMREP-ERMMGEFMQPGGRLMLSKLGLQDCLEDIDAQKATGLAVYKDGKEADAPFPVDNNNFSPSARSFHNGRFVQQLRRKAFSLSNVRLEEGTVKSLL-EEKGVVKGVTYKNKE-----------GEETTALAPLTVVCDGCYSNLRRSLNDDNNAEIMSYIVGY-------ISKNCRLEEPEKLHLIL------SKPSFTMVYQISSTDVRCGFEVLPENFPSIANGEMSTFMKNTIVPPKLRKIFLKGIDEGAHIKVVPAKRMT-STLSKKKGVIVLGDAFNMRHPVVASGMMVLLSDILILRRLLQPLSNLGDANKEVINSFYDIRKPMSATVNTLGNAFSQVLIGS................................................................................................................................................................. 407
4 -28.700[C] COG2440 Ferredoxin-like protein  ali follow..  20  4...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AVTKLRVEEKLYQNRYLVDPGRP-HIKVRP-----HERPSANLLALTHICPAKCYELNDKG-----QVETTSDGCMECGTCRVLCEASEIVWNYPRGGFGVLFK.. 97
5 -28.300[HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases  ali follow..  10  1..................................................................MRTQVAIIGAGPAGLLLGQLLQR------SGIDAVILETRSRQ-EERIRAGVLEQGTVDTLNEAGVGERMRREG-LVHHGIDLLFEGKRHRLDL--TALSGGRSITVYGQHEVVKDLIAARIGQGAPLLFEVSEVSLHDLESATPSVRFVHE-------------GVPQTLHCDYIAGCDGFHGICRPAIPAQRQAVFERVYPFAWLGILAEAAPAADEL-----------IYASHARGFALFSMRSPKITRLYLQCKPDENLAEWSDARHTRLENNDGWHLKEGPILQKSVTPMRSFVC--------ETMRHGRLFLAGDAAHIVPPTGAKGMNLAVADVRVLAQALTARYRQND--TAQLDGYAERCLQRIWRAEHFSWWMTS...................................................................................................................................................................... 348
6 -27.500[H] COG1635 Flavoprotein involved in thiazole biosynthesis  ali follow..  18  9...................................................TRAIFDEYSKTFLDYTDIDVALVGGGPANLVAAKYLAE------AGVKVALYEQKLSLGGGMWAGGMMFPRIV----------QEEATRILDDFGIRY---------------KEYESGYYVANSVESVGKLIAGATSAGAEVFNLVSFEDIMIRENDRVTGIVINWGPVTTQRLH----VDPLMIRTKLVIDGTGHEAVVCNTILRKIPNA-----KIGELGLLGEKPMWSEVGERLAVNAT---------------------------------------------------------------------------------QEIYPGLIVAGMAANAATRAPRMGPVFGLLSGEKAAKLALDRLKT..................................................................................................................................................................................................... 259
7 -25.600[HC] KOG3855 Monooxygenase involved in coenzyme Q (ubiquinone) biosynthesis  ali follow..  1...............MSKDRVLARNLRTSVCGTRILQRTCSTVVTHDVSTSCSNESNALNNSTDDGPQHDIAIVGGGMVGIALAASLASKPLT--KHLNVAIIDNNPLLGRRNI--STVTPATISFLKDIGAWKYIEQQRHAYFDKMQALDIQDTMLMMYIKMFWGKHIAIYIIQESDLQKTVYPARLNALTGLGEVPSTTDLFMRGRLAKLEL-----------------SDGNRVYAKLVVGADGSKSRVRELAGI--------KTTGWNYSQNAIICTVEHTAENYTAWQRFL------PNGPIALLPIGDKFSNIVWTMDPKEASDRKLMNEDDFIKAVNDSAKERFETPPKVVKLSSERMMFPLSLRHAKDYVSKRVALVGDSAHTVHPLAGQGVNLGFADACALSKAIAEGIALGT-EANLLKRYEAE....................................................................................................................................................................................... 448
8 -24.800[CR] KOG2614 Kynurenine 3-monooxygenase and related flavoprotein monooxygenases  ali follow..  12  2...............................................................EAESTQDIIIVGAGISGLATALGLHR------LGIRSIVLESSEQLRA---FALSLYFNAWKAMEALGISQHIRSLG-DRFQGWVVRPISAGDPPKEMLFPESEEYEVRCVQRKLLLDALAGELPQGTIRF--SSKLVHIELSGHYKMV-----------------HLSDGTILKTKVLVGCDGVKSVVGKWLGFKNPVKTSR------VAIRGIAHFQTGHELGRRFFQFY------GNGVRSGFISCDQNTVYWFLTHTSTDLDKKNHQKIKQFVLTKIKPDNIKSILETTDLDSLVMNPLMY---LLWANIAKDNVCVAGDALHPMTPDIGQGGCSAMEDGVILARCLGEAMKAKNMKEDGLKKYAGSRKWRSIDLITTSYTV........................................................................................................................................................................ 365
9 -19.900[R] COG2509 Uncharacterized FAD-dependent dehydrogenases  ali follow..  15  1................................................................MEQKFDVVIIGAGPAGLFAAYELVE-----RSNLKVLIIDEGGDVDQRIMSGVGLVWEVDQILLRHEAPRNLYKGDPEQIKYWERKAAQAGVKFIPIIQRHIGSDNTPKVIKS-----IKNYLESKGVKFLLWTKALEF---NKGWVKVQRG---------------KDVFTIEAKYIIVAPGRGGAWFHEVAKKIGLKARHGPIDVGVRVEVPAIIMEPITSINHDPKFHIYTDTYDDFVRTFCT-REKKSNNTNFALLTRIELTEGGKPIIQRLGDLRKGRRSTWSRIRKSDVEPTLKHVTPGDIAMA-ETSIENVFAAGDGAGLS-----RDIVNAAATGIMAARGILVKEGLYNLKDFK.............................................................................................................................................................................................. 468
10 -19.700[R] KOG2960 Protein involved in thiamine biosynthesis and DNA damage tolerance  ali follow..  13  1MAPATAKTDLPVEKTAHNTVVKSEMGALSKAYPTYSLDESFSFAPIRESTVSRAMTRRYFSDLDKYAESDIVIVGAGSAGLTAAYYIGT----RRPDLKIAIIEASVAPGGGAWLGGQLFSAMVVRKPADLFLNEIGVPYEDEGDYVVV-----------------------KHAALFTSTVMARTLALPNVKLFNATAVEDLIVKEGKQRIAGVVTNWTLVSLNHGLQSCMDPNTINAHLVVSATGHDGPFGAFC--------------------------------------------------------------------------VKRLASAQLVSNLHDMRPLDMNRAEDLIVKGTREVFPGMIVGGMELSEFDGANRMGPTFGGM-----------MFSGIKAAQEALAIFDERKAVNEKY............................................................................................................................................................................................. 327
11 -19.500[R] KOG2852 Possible oxidoreductase  ali follow..  10  1................................................................MSNSRNIVIVGGGITGVSCLYFLAHHPSFNRDRDTITLFESAGIASAASGKASGLAALSYNLHKELSDQYDGVNKWGYRALDTWSIKADENCQQPDKLPEGIEWIAP-QVHPYKFCHAIYEEASKVANVTLVKGHVLSVDENEVEYRLIGDDYAPDEEEEITSAEELHTIHSMEATHIIVAAGPTPQLIPNLRIS--------------GARIHSITIDLPIKLNGNAVFSEITYKDGTIAAPEFYAREDELYVCGEFDDEPLPELDTKVDQDKCALIKQCANHFHQIIRDSPVKVRQACY--------LPISNATGAPVIGKIGSVAAAHGCWGITLGPGTGKVLSELILDGAVTSNIDLLDPEGSLE........................................................................................................................................................................................ 382
12 -17.600[R] COG3573 Predicted oxidoreductase  ali follow..  18  1................................................................MADDADVIIVGAGLAGLVAAAELA------EAGKKVIIVDQEPEQGQAFWSFGGLFLVDSPEQRRMRIRDSHDLDFWPRKWAEAYVGFAAGEKRSWLIERGLKIGHGNSVPREPFVQRVREAQKRGLISFKFRHRVNELTRA-GDVVTGVRGDVLEPSRGHKSSRDISGDFELHAQAVIVASGGIGAITEQAGGSIINRDRM-PGPSSLWLDARGKRLPVPLYPGFDTLGTLSHIMSTGFDYSWFFIVEADLSKLVMNALAGGEPLLEVAQVEREMLDPANGPLIAVRLNGGLQTDLDSRVLGADG---------PGLYAVGEAAGFGAALEGTFLGGCIFSGRSAGRAAGRSVA...................................................................................................................................................................................................... 552
13 -17.100[C] KOG2404 Fumarate reductase, flavoprotein subunit  ali follow..  17  2..................................................................SLSPVVVIGTGLAGLAAANELVN-----KYNIPVTILEKASSIGGNSKASSGINGACTETQRHFHIEDSPRLKGKGVQELMAKLANDSPLAIEWLKNDLLAQLGGHSVARFEIVSALSNETKPELVKINLDSKVVDIH-EKDGSISAVVYEDKN-----------GEKHMVSANDVVFCSGSKEMLKEYAPELVNLPTTNGQQTTGDGQRLLQKLGADLIDMDQIQVHPTGFIDPNDRSSSWKFLAAESLRGLGGILLNPITGRRVQKLTLSQVVSEYNLPITVAQLCGGARINVKAQVIGKNDERLLK-----GLYAAGEVSGGVNRLGGSSLLECVVFGRTAAESIANDRK...................................................................................................................................................................................................... 470
14 -16.900[S] COG3349 Uncharacterized conserved protein  ali follow..  16  1....................................................................MRVAIAGAGLAGLSCAKYLTD------AGHTPIVLERRDVLGGLVAAGDWYYPNMLQLLKELGIEDRLQIASILRNNDMLTWEQKIRFAIGLLPAIVRGQKYVEEMDKYSFSDWLVDYITERGGEVRLNAPLKEILLNPDGTVKGFLLRG----------LNGEPDEVITADFYVSAMAVDPLMLPQPWQQMEFFQKLEGLEGVPVINLHLWFDRKLTDIDHLLF-SRSPLLSVYADMSNTCREYANPDRSMLELVLAPAKDWISKSDEEIVSATMVEPDHFKGDNPAKLLKSHVVKTPRSVYKATPGRQQANFFLSGSYTMQRYLGSMEG---AVLSGKLTAQAICESLPEDNTSN................................................................................................................................................................................................ 464
15 -16.700[C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit  ali follow..  12  1.............................................................MKLPVREFDAVVIGAGGAGMRAALQISQ------SGQTCALLSKVFPTRSHTVSAQGGITVALQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALC----------IETGEVVYFKARATVLATGGAGRIYQS--------TTNAHINTGDGVGMAIRAGVPVQDMEMWQFH-GVLVTXGCRGEGGYLLNKHGRDVVARSIMIEIREGRDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYEKGEDVVVPGLFAVGEIACVANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLK-VIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSR............................................................................... 542
16 -15.500[E] COG3075 Anaerobic glycerol-3-phosphate dehydrogenase  ali follow..  11  1..................................................................MRFDTIIMGGGLAGLLCGLQLQKH------GLRCAIVTRGQ--ALHFSSGPHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLAVETARLQNQLQRQFVRQGGVWMPGDEVKKVTC-KNGVVNEIWTRN-------------HADIPLRPRFAVLASGSGGLVAERNGIREPILGLD------------------------------------------VLQTATRGEWYKGDFFAPQPWQQFGVTTDQTLRPSQAGQTI------------------------------ENLFTIGSVLGPIAQGCGGGV--CAVSALHAAQQIAQRAGGQQ................................................................................................................................................................................................... 419
17 -15.400[C] KOG2403 Succinate dehydrogenase, flavoprotein subunit  ali follow..  13  2.......................LSLKKGITKSYILQRTFTSSSVVRQIGEVKSESKPPAKYHIIDHEYDCVVVGAGGAGLRAAFGLAE------AGYKTACLSKLFPTRSHTVAAQGGINAALQDAIHYMTREAPKSVIELEHYGMPF-TEDGRIYQRAFGGQSKDFGKGGQAYRHAMLHTLYGQALKNNTHFFIEYFAMDLLTH-NGEVVGVIAYN----------QEDGTIHRFRAHKTVIATGGYGRAYFS--------CTSAHTCTGDGNAMVSRAGFPLEDLEFVQFH-GCLITEGARGEGGFLLNSEGRDVVSRAITMEIRAGRSHLPPEVLKERLPGISETAAVFAGVDVTQEPIPVLPTVHYETGEDKVIPGLMACGEAACVANRLGANSLLDLVVFGRAVANTIADTLQPGLPHKPLASNIGHESIANLDKVRNARGSLKTSQIRLNMQRTMQKDVSVFRTQDTLDEGVRNIT-EVDKTFEDVHVSDKSMIWNSDLVETLELQNLLTCATQTAVSASKRKESRGAHAR............................................................................... 581
18 -15.100[O] COG3634 Alkyl hydroperoxide reductase, large subunit  ali follow..  15  196...................................................DTGAEKRAAEALNKRDAYDVLIVGSGPAGAAAAVYSARK------GIRTGLMGEENYISVPKTEGQKLAGA---------------LKAHVSDYDVDVIDSQSASKL----VPAATEGGLHQIETAS------AVLKARSIIIATGAKWRNMNVPGEDQYRT----------KGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVE-----HVTLLEFAPEMKADQVLQDKVRSLKNVDIILNAQTTE------KGDGSKVVGLEYRDRVSGDIHSVALAGIFVQIGLLPN-THWLEGALERNRMGEIIID----AKCETSVKGVFAAGD----CTTVPYKQIIIATGEGAKASLSAFDYLIRTKIA................................................................................................................................................................................................. 521
19 -15.000[C] KOG0042 Glycerol-3-phosphate dehydrogenase  ali follow..  11  53...................................................EPPSREAQLLTLQNTSEFDILVIGGGATGSGCALDAVT------RGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAIMK-RMVKEALHERANLLEIAPHLSAPLPIMLPVYKWWQLPYYVGIKLYDLVIALTAARYGAATANYMEVVSLLKKTDPHVSGARCKD----------VLTGQEFDVRAKCVINATGP-------TDSVRKMDDKDAAAICQPSAGVHIVMPGYYSPESMGLLDPATSDGRVI----FFLPWQKMTITTDTPTDVTHHPIPSEEDINFILNEVRNYLSCDVEVRRGDVLAAWSGIRPDPKSADTQSISRNHVVDISES----------GL-ITIAGGKMAEDTINAAVKESEVAQHLAATYGDKAFEVAEYACTAVDMISRRTRLAFLNVQAAEEALPRIVELMGRELNWDDYKKQEQLETARKFLYYEMGYKSRSEQLTDRSLLPSDIDRYKKRFHKFDADQKGFITIVD----VQRVLESINVQMDENTLHEILNEVDLNKNGQVELNLQLMSAIQKGRVSMKTAEENLD-PVDRSCGG...... 726
20 -14.600[E] KOG2844 Dimethylglycine dehydrogenase precursor  ali follow..  11  3.................................................GHRLARWRWARSYTTAVANADVVVCGGGISGTSIAYHLAKR------GKKALVEKDSIGCSGATGLSAGLLQAIAQASLDLYSHLATTCKFRYIKCGRTYLASSMANEILLRRMYSRGVVHNDALDPVALCQHLALIAKDYGALIYESNPVLEVHIGDEKQVYGVSTKMG----------------FIETSHFVDAAGIAGSHLVKALPHQHVQTAAYPCTYSYIHTSKLPTGSVSDMTPIFNDLDGNVMLRTTSFKTLCAGFAEESIRPLARQTGSATPWQHPEPDWNTFGMALRFTAGRQFYKTHPNLEKLISRCPMLGDCNHGDLIVDKLPTIGESSQAKGYWVMCGMNGQLSLAGGLGKILGELMCESQSSTADVARVDVG....................................................................................................................................................................................... 421
21 -14.500[O] COG0492 Thioredoxin reductase  ali follow..  13  1.............................................................MSRKEELYDITIIGGGPTGLFAAFYGGMR------QAKVKIIESMPQLG-----GQLAALYPEKYIYDV--------------------------------------AGFPKVKAQDLVNDLKRQAEQFNPTIALEQSVQNVTKETDDTFT-----------------IKTDKETHYSKAIIITAGAGAFQPRRLEVEGAKQYEGKNLQYFVNDLNAYAGKNVLISGGGDSAVDWALMLEPVAKNVTLIHRRDKFRAHEH-SVELLQKSSVNILTPFAISELSGDGEKIHHVTIQEVKGDAVETLDVDEVNTKMETNIPGIYAAGDICTYPGKVK---IATGFGEAPTAVNNAKAFIDPTA................................................................................................................................................................................................... 319
22 -14.400[Q] COG1233 Phytoene dehydrogenase and related proteins  ali follow..  13  2...............................................................AVTQTRDAVIIGGGHNGLVCAFYLAKA------GLKVTVCEARGVVG-----GAAVTEEFHPGFR---LNPRVIADMGLRELGLTFLERPISNFLPISDDKYIKLGGGLERTQEEFRKYMAKACEAAGVEILLDAPVEAVHI-DGGKAAGVQLVD---------------GRQIMAPIVSANVNPALLYKKLVPPSAKGQGISKAPIVEMLIPSSLDTSLAPPGQHVASLFCQQFAPELPDGRSW----DDAREAAADLIIDTVDQWAPGFKASVLGRMILSPLDLERKLIGGDIMHGHMSLDQLWATRPLLGHASAGLYMCGAGT---HP--GGGVSGN--PGRNAAREILRDKDFAT................................................................................................................................................................................................... 534
23 -14.400[H] KOG4254 Phytoene desaturase  ali follow..  11  3.........................................................RRSFSTLPKKKWDAVVIGGGHNGLTAAAYLARG------GLSVAVLERRHVIG-----GAAVTEEIVPGFK-GLLRPCIIRELELGRHGLKLLKRSPSSFTPCLDGRYLLLGPDQDLNHSEISKFIANAAKEAGAEIFTNAEVSEILTEDSSIVKGVLLAD---------------GTRVESSAILSNATPYRTYVELVPTNKNSDYSSATTKINLAVDKLPQFQCCNTNHSEMTIPSTLDNTISPPGKHVINLFPTYREAFAQRCFKLIDEYAPGFSSSIISYDMLTPPDLERELTGGNIFHGAMGLDSLFLMRPVKGWSNKGLYLCGSGA---HP--GGGVMGA--PGRNAAHVGTNNHDDMGDVAAGLRVFAEQMKSKSGGLDEFVGQMDAIEKQVSEFEAVISVLDRYVSVLESKI--------------------RAEYRHPHHQRRSNDSVVTD.................................................................................................... 647
24 -14.300[S] COG4716 Myosin-crossreactive antigen  ali follow..  11  3................................................YTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIR--DGHMAGERIHLFEELPLAGGSLDGGGREMENHFECMWDM-SLGDQTIEEFFSEDFFKSNFWVYWATMFAFEKWHSAVEMRRYAMRDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKAIELTPDDLVFVTSSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVFYQDLPAESEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAIHRQPHFKEQECTGQEITEEWLYHLGVPVDKIKDLASQDYINTVPPRVKGDRPKVIPVNLAFIGNFAESPSRDTVFTTEYSIRTAMEAVYSFLNVERGIP-AFYYLNDKKAIKDMDLPIPALIEKIGHKKIKDTFIEELLKDA........................................................................................................................................................ 587
25 -14.300[R] KOG2820 FAD-dependent oxidoreductase  ali follow..  11  2................................................................VGKAYDVIVVGAGIFGSCTAYHCQR------LGLRTLLLEQYSLGHSNGSSHGKLVGDSYLQIEEL---EKKRGEKLWNKLGLLWAATGNQVDSISGHLKKHNIDHEVLPGTKITERYFQEEFITLGGTIQDNEPVISYG-ETDNVIVNVKT----------------STGEYKTNKIIFTVGCITKFFPNVNFQIKPISLA----------CYWNAKDEKNNHLLDEKHFPVVIAKNLEKKEYFFALPDTDYPGAIKLVLDEGDDLAGDLSHPTKNNQELVTIPGSFIKDFELGHKNGSSHGKSRITRYAHTEVEYVDLVGDAYNQIFELERIGEKLWKKTGLLEVEKIHTNLKLKGIKHEVIKGTE------------VGKRYPQFKFDDSWNGLIDPMGGVIYADKWLNAFRDEFKKIGGIIHDREIVLSHSEISNNLFVTTNKSRYSSKKI--IFTVGCWITK-PDLKFNIEPISISVCYWKTKNESDSHLLNEDHHYSLPDTDYPGSMKFCYHFDKCIYTNSPDIIGPTKNPNILVGGCGSGSGFK.. 668
26 -14.000[H] COG1232 Protoporphyrinogen oxidase  ali follow..  11  1...........................................................MGGGRMGQHVETLVIGAGPAGLTTAYTLAK------AGRGVTVLEMD-----ETYVGGISSQEIVDLWNEILPDDFI-----DRPRLSRIYYREKFYAYPLKPIAAPTTFHQWVRNQGMMWEACADKVMALGGDVRMGRKVDGLHFDKIAKLWTVAVT-----------CADGRKEIYTADNVVSSAPIRELMQSISPTPISVFHAGELMYRDFIT------------------VVLIGKPQKELPDNWIYIHDPSVKVGRVQNFRSWSPEMIVTSDEELVAQAKREIGKIGLMAPADVYDACVKAYPVYDDAYAEHVKMPGLHLVGRNGMH----KYNNQDHAMMTGLLTAENIIAGETLHDVEVNEDAEYGEAGVSGARQALRSERAVPTK..................................................................................................................................................................... 501
27 -13.900[C] COG0578 Glycerol-3-phosphate dehydrogenase  ali follow..  11  2..................................................................ETKDLIVIGGGINGAGIAADAAG------RGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEF--RLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR-ARLVLANAQMVVRKGGEVLTRTRATSARRENGLWIVEAEDIDTG------------KKYSWQARGLVNATGPVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVHTQKQAYI------------LQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNNTHFKKQLSRDDIVWTYSGVRPDDESDSPQAITRDYTLDIHDENGKAPLLSVFG---KLTTYRKLAEHALEKLTP..................................................................................................................................................................................................... 371
28 -13.800[R] COG0579 Predicted dehydrogenase  ali follow..  12  2.............................................................AQNDHETVDMLLVGAGIMSATLAVLLKEL----DPNLKMEVVELQESGAIENPVPHLSFVRGSEGIAYLKKRFESLTKHHAFETMVYSEDKATLAEWMPLMMPGRPAEGGTDVNFGALTNQLLQHLAQQGAQIRYNQKVTHLRRADNGWRVTVKDTRN------------GGDREIQARFVFLGAGGGAPLLQLSGIPEGKGFGGFPVSGQWLRCDNPEIVKQHQAKVYSQAEVGSPPMSVPHL---RVVDGKKSLLFGAGFSTKFLRHGSFLDLPLSVRPGNILPMLSVARDNMDLTRYSPEQRLEALRKFYPEARAEDWRLAGQRVQIIKKGASPGASVTVSIMLGLIERCFPEQARSPEWSAKLKEIFPAREKELESD............................................................................................................................................................................... 477
29 -13.400[E] COG1231 Monoamine oxidase  ali follow..  12  4........GSVGISFMQSGARTPTRRQLLSAIAKVGGTAALYQAMTSLGHAAETRFPGPPNLQGARPGASVIVLGAGLAGLLAAFELRKA------GYKVQILEFQNRPGGRNWSGPWRIPHHHRTLLHYCKQFGVALEPFIQFNHSGWIHSSQAFG-SMGFFMNHEMQTTMFQPVGGMDMIGKAFAKQVEGLITYNAKVSKIAQDDKGVVVTYADTVTG------------KVTEAKGDWCVCTIPLGILGQMDLAVTDEMMAAIKAVPYSGQVKMGLEMNRR----------------------FWSYPNNNLFQDGPAVLLGAFARDLGGMTPEQRIEVALAQKSYRKEFRTGASVAWSRVPWTLGCCARWNE--DRRIVLAGEHASYVGCWM-EG---ALLSSLDAITRLHKRALSA.................................................................................................................................................................................................... 541
30 -13.100[R] COG3380 Predicted NAD/FAD-dependent oxidoreductase  ali follow..  12  1..................................................................MSVPIAIIGTGIAGLSAAHALRSA------GQTVQLFDKGHGS------GGRMASKRSEQYFTARDRRFLDALQHWREEGWVDEWKPALYQYRDGQLSPSPDEQPRWVGIPRMSAITRALLT--DLQVVFSCRITEVFRGKQHWHL----------------QDSEGQNHGPFNQVLIA--ATPLLASVPKLAATAASVVMEPTWAVALGFREVLDTPVQGCFVHGSPIAWLACNRSK------GRDTTLDTWVLHATSQWSRQHIDMAKEDVVEHLRCA---FAEVIGCAVPEAAFSIAHRWLYARPAEAHQWGALACGDW------CSSGRVEGAWLSGQEAARRLLEHL....................................................................................................................................................................................................... 327
31 -12.800[O] KOG0404 Thioredoxin reductase  ali follow..  11  17..........................................................SKSVLSRMIHHKVTIIGSGPAAHTAAIYLARA------EMKPTLYEGMMANGI-AAGGQLTTTTDIENF----------------------------------------------LSGSELMERMRKQSAKFGTNIITE-TVSKVDLSSKPFRL--------------WTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQQGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAEFLTKYASKVYILVRKDHFRASVIMQRRIEKNPNIIVLFNTVALEAKGDGKLLNMLRIKNTKSNVENDLEVNGVKGQVDEEETGYIKTVPAAGDVQDSRYRQAVTSAGSGCIAALDAERYLSAQE................................................................................................................................................................................................... 342
32 -12.800[H] COG0029 Aspartate oxidase  ali follow..  12  7............................................................KHEIRDMKFDVLVVGEGLAALTLLLHLPP-------SLKIGVISRNKYDEPSSYWAQGGISAVFEAAVRQIVCEGGDVLRWLIDQGVPFTREDGEIHLTREGGHSERRHVDDMTGRGIMRALQAKVAQLPNVIWIRQYEAVELLSD-GQAVSGVIAES----------LADGEVTVFSAPTVVLAAGGLTGLYQYATNPHASKGEAIAMAWRAGATENLEFVQFHPTAFQIEGRVISLITEAVRGEGGLLYNVANRDVVARAIYSEMQAHGTHQGTAFVEQHF---PNLVEITRGCDLSQHRVPVSPAAHYDVAGRTNIEGLYAIGEVAN-------CGLHGA---NRLASNSLLECVVMGKACAQSVTDTAGSASRLRLTLPERIETPFHPNLLADLRAILWNHAGIVRSN-----------TGLEIGLQNMAQLQERHASVLPYGQALRAQNIFDAAHLVLLSAAARKESRGGHFN............................................................................... 499
33 -12.700[C] COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit  ali follow..  22  57..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YICWKFCPEPAIYIKEDG-----FVAIDYDYCKGCGICANECPTKAITMVREE.......... 104
34 -12.700[E] COG0665 Glycine/D-amino acid oxidases (deaminating)  ali follow..  11  1....................................................................MRVVILGSGVVGVASAWYLNQ------AGHEVTVIDREPGAALETSAANALAEYSRDCLKA--LRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDAGVPYQLQLFTQNLARMAEQAGVKFRFNTPVDQLL-CDGEQIYGVKC----------------GDEVIKADAYVMAFGSYSAMLKGIVD---------PVYPLKGYSLTIPIAQEDGAPVSTILDETYKIA--------ITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMVVRDLYPRGGHVEQATF------------WTGLRPMTPDGTPVVGRTR-WLNTGHGTGWTMACGSGQLLSDLLSGRTPAIPYEDLSVARYSRGFTPS................................................................................................................................................................................... 422
35 -12.500[C] KOG3851 Sulfide:quinone oxidoreductase/flavo-binding protein  ali follow..  10  1.........................MNRRLPGTISQCQKLLLATHNHAPTAFSTRFLSTSRVNRERQECQVLVVGGGTGGCAMAAKLSSRL----GSDKVVVLEPEDKPMFTLIGGGMKRLDQSHR---------------------------------------------------------MADVLPTKAKWVKE-KALEFDPDNNTVST-------------------SGGKTIKYDFLIIATGLQLNYGKIPGLVEALETPDSNVCSIYSPKYVDHVYECLRRTNKGNAIFTFPNCPIKCAGA-YFRKMGRRDNVNIIYNTSLPVIFGVKHYAEALMKLIKRRNITPPMSTPDVVANCKKLVTPTGFVDVDQLT-SNVFAIGDSASSPNSKTAA---AAAAQSPVVFKNVMAAIEGKAPTD................................................................................................................................................................................................ 374
36 -12.500[C] COG1146 Ferredoxin  ali follow..  15  1..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MAEAKNAPLIGKDALGREVRDLSKVPWWGVDRKEIEWYPTI-DYDKCVT------CGICFVTCGRRVFDF--DKKEGKVIVARPYNCMVACQTCMNLCPTGAISFP............. 97
37 -12.400[M] COG0562 UDP-galactopyranose mutase  ali follow..  11  2...............................................................TESKNYDLIVVGSGLFGLTVAERAAS-----QLGKKVLIVERRSHLGGNAYSGAHLNTRVWEYVNQFTSFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGKYYSPDEARELIKENLEEKAISLI---GRPLYE-----AFIRDYTAKQWQTDPKNLPAGNITRLPVRYNFNNRYFNDEGLPTDGYAAWLEKDVRDDLRASNPDAPVVYTGPLDLYFNYAEGKLGWRTLDFETEVVETGDFQGTPVMNYNDADVPFTRIHEFRHFHPERDDSYPKDKTVIMREFS--RFADNEDEPYYPINTPDDRDMLKQYRLLAANKVLFGGRLGTY----QYLDMHMAIGSALSMFDNKLVPFFEEGTPLEQERGH.......................................................................................................................................................................................... 401
38 -12.000[Q] KOG0029 Amine oxidase  ali follow..  14  18.........................................................STDEKMKKKRSPSVIVIGGGMAGISAARTLQDA------SFQVVVLESRDRIGGRVHTGASWLHGVCKENPLAAVIGRLGLPLYRTSGDNSVLYDHDLESYALFDKAGNQVSQELVTKVGENFEHILEEICKVGYRPVINTLSKGLDIRLSHRITKISRRYSGVKV------TTEKGDTFVADAAVIALPLGVLKSGMITFEPKLPQWKQEAINDLGVGIENKIILNFDNVFWPNVEFLGVVAETSYGCSYFLNLHTSHPVLVYMPAGQLARDIEKKSDEAAANFAFS--QLQKILPDASVSRWGSDINSLGSYSYDI----DNLFFAGEATSSSYPGSVHG---AYSTGVLAAEDCRMRVLE..................................................................................................................................................................................................... 464
39 -11.900[H] KOG1276 Protoporphyrinogen oxidase  ali follow..  12  10.....................TQSLLPSFSKPNLRLNVYKPLRLRCSVAGGPTVGSSKIEGGGGTTITTDCVIVGGGISGLCIAQALAT--KHPDAAPNLIVTEAKDRVGGNIITGNSFQPSMLTMVVDSGLKDDLVLGDPTAPR--FVLWNGKLRPVP-RPSPPGREESVEEFVRRNLGDEVFERLIESGVYAGDPSKLSKLEQNGGSIIGGTFKAIQERKNAPKAERDPRLPKPQGQTVGSFRKGLRMLLGSKVKLSWKLSGITKLESGGYNLTYETPDGLVSVQSKSVVMTVPSHVASGLKGFGQLHPRTQGVETLGT-IYSSSLFPNRAPPGRILLLNYIGGSTNTGILSKSEGVRVWPQAIPQFLVGHFDILDTEGLFLGGNY------VAGVALGRCVEGAYETAIEVNNFMSRYAYK................................................................................................................................................................................................. 537
40 -11.700[ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases  ali follow..  13  150......................................................................VAIIGAGPAGLACADVLIRN------GVAVTVYDRHPEIGGLLTFGKSLLARRREIFSAMGIHFELNCE-NTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANM-VKNAREEGANFEFNVQPVALELNEQGHVCGIRFGEPDAQGRRRPVPVEGSEFVMPADAVIMAFGFNP----------HGMPWLESHGVTVDKWGRIIADVESQYR---------------------------------------------------------------------------------------QTTNPKIFAGGDAV--------RGVVTAMAEGRHAAQGIIDWLGVKSVKSH............................................................................................................................................................................................... 479
41 -11.600[C] COG1148 Heterodisulfide reductase, subunit A and related polyferredoxins  ali follow..  10  126...............................HMDDPEGATEKAKDLVRMAVAKARLLEPLEASKVSVDDKALVIGGGVAGIQTALDLADM------GFKTYMVEKRPSI------SGRM--GQLDKTFP-----------------------------------------TLDCSMCILAPKMVDVGKHDNIELITYAEVKEVDGYIGNFKVKIEKKPRYIDED-PIEMPNYFDEGIGMTKAVYIPFPQAVPLCATIDKDYCIECMLCDEICERGAVKHDQEPEEIEIEVGTIIVATGYDAYDPTEKLEYGYGR-HTNVITGLELERMINASGPTDGKVIKPSDGEKPKRVAFIHCVGSRDEQIGKPYCSRVCCMYIMKNAQLI-TEVTLYYMDIRAFGKGFEEFYKRSQEKYGIAEILENPDLTLTVRSEDTLLGKVTEYDYDMV-VLGVGLVPPEGSEKLRQTIGLSKSADGFLMEAHPKLRPVDTLTDGVYLAGVAQGPKDIPDAVAQASGAAARAAIPMVKGEVEIEPIVAVT---------DSDVCGGCEVCIELCPFGAISIEE------GHANVNVALCKGCGTCVAACPSGAMD............... 647
42 -11.600[J] KOG2311 NAD/FAD-utilizing protein possibly involved in translation  ali follow..  10  24.......................................................RLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARC------GSRTLLLTHRVDTIGQMSCGGIGKGHLMREVDALDGLCSR-------------ICDQSGVHYKVLNRRKGPAVWGLQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVDGSTVYAESVILTTGTFLMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTPPRIAKESINFSILNKHIPDPQGLSMTLPAELQEKMITCGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLETHLVQRLFFAGQINGT------TGYEEAAAQGVIAGINASLRVSRKP................................................................................................................................................................................................... 461
43 -11.200[J] COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation  ali follow..  11...............................................................SVVSQSYINVIGAGLAGSEAAYQIAER------GIPVKLYEMRGVKSTPQHKAELVCSNSLRGDALTNAVGLLKEE----------MRRLGSVILESAEATRVPAGGALAVDRDGFSQMVTEKVANHPLIEVVRDEITELP-TDVITVIATGPLTSDALAEKIHALNDGAGFYFYDAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEIEVMAKRGIKTMLYGYAVVQLRQDNAAGSLYNIVG---QTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQTYRSKKQPNLFFAGQMTGV------EGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAHYITHA............................................................................................................................................................................... 409
44 -11.100[D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division  ali follow..  11  2...............................................................FYTETYDVIVIGGGHAGTEAALAPARM------GFKTLLLTHNVDTLGQMSCNPAIGGIGKGHLVKEVDAMGGLMAHAADKAGIQFRTLNSS-------KGPAVRATRAQSDRVLYRQAVRTALENQPNLDIFQQEATDILIEQD-RVTGVST---------------KMGLTFRAKSVILTAGLENYEGGRAGDSASVNLSHRLRDLGLRVDRLKTGTPPRIDARTINFDILAKQHGDEVLPVFSFMGSVDDHPQQIPCYITHTNEQTHEVIRNNLDRFDVQMGIVNSMKGLENARIVKPGYPRDLKPTLETKSISGLFFAGQINGT------TGYEEAAAQGLLAGINAGLYVQEKD................................................................................................................................................................................................... 399
45 -11.000[C] KOG3256 NADH:ubiquinone oxidoreductase, NDUFS8/23 kDa subunit  ali follow..  14  1................................................................................................................................................................................................................................................................................................................................................................................................MSLTMRIFTASRNGQRLFGSHGARL---LAAQRAEPKDIVEVPKGYVYVNNKELSMEFADITDRAASTMFFGELLRGFAVTLAHIFKEPAT-----------------------------INYPFEKGPLSPRFRGEHALRRYPSGEER------------------IACKLCEAICPAQAITIEAEERADGSRYDIDMTKCIYCGFCQEACPVDAIVEG............. 175
46 -10.700[C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)  ali follow..  26  66..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NLCAVACPVGCISLQKAETEDGRWFRINFSRCIFCGLCEEACPTTAIQLT............. 119
47 -10.700[E] KOG3923 D-aspartate oxidase  ali follow..  10  9...........................................................FGGVSTVSSLRVAVVGEGVIGLSTATAILD------LAEKRNIPAPEIHIFHHKPFEKILSRHIAGLFRIDSGSEIDRKYGYDTFEKLATLWREYGGLSGVQLVSGHIHYTAYTSEGLRFCPFLKKELMTKGVRFTQR-RIGNL-----------------------------EELGAEFDVVVNSAGLLG---------GVLAGDDAGNMKPI--GVLIRVDAPWQKHFLYR-----------DFSTITIPVIDHVYMG--TVKQEGAFGPNNVTSADIQDITSRYVALQPSFKRVHMLSSFVGYRPGRKQVRVEK-GSKKFTVVGHS--------GNGFTLGYGSAVHAAHIVLDLPLDAYHGLVPINATISEWVKYLDD................................................................................................................................................................................ 383
48 -10.600[P] COG2072 Predicted flavoprotein involved in K+ transport  ali follow..  11  1................................................................MNQHFDVLIIGAGLSGIGTACHVTA----EFPDKTIALLERRERL------GGTWDLFRYP--------------------GVRSDSDMFTFGYKFRP----WRDVKVLADGASIRQYIADTATEFGVDIHYGLKVNTAEWSSRQCRWTVAGVHEA----------TGETRTYTCDYLISCTGYGGRCVHPQHWPEDLDSGKKVVVIGSGATAVTLVPAMAGSNPGSAAHVTMLQRSPS----YIFSLPAVIQRKLYQACRRWPKLMRRLLLWEVRRRLGRSVDMSNFTPNYLPWDERLCAVPNGDL--FKTLASGAASVVTDQ---IETFTEKGI--LCKSGRIEADIIVTAVDGAEYQLPEKMTYKGVLLENAPNLAWI............................................................................................................................................................................ 387
49 -10.600[C] KOG1335 Dihydrolipoamide dehydrogenase  ali follow..  11  12......................................AKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKAAQL------GFKTVCIEKNETLG-----GTCLNVGCIPSKALLNNSHYYHMAHGTDFASRGIEMSEVRLNLDKMMEQKST---------KALTGGIAHLFKQNKVVHVNGIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALS--KKVPEKMVVIGAGV-GSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGA---------TKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKI--PNIYAIGDVVA---------AHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTH........................................................................................................................................................................................ 396
50 -10.500[C] COG1251 NAD(P)H-nitrite reductase  ali follow..  12  139.............................................................EACARRSKRGAVVGGGLLGLEAAGALKNL------GVETHVIEF----------APMLMAEQLD---------------------------------------------------QMGGEQLRRKIESMGVRVHTSKNTQEIVQQGNEARKTMRFAD---------------GSELEVDFIVFSTGIRDKLATQCGLAVAQRQTSDPDIYAIG-NRVYGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLK-GVDVGGIGDAHGRTPGARSYVYLDLVGDTSDYGNLLQLVLNAIELPENPDSLILPSHAGSGKPAIGVDKLPDSAQ--CFDVTKGDLIAAINKGCHTVAALKAETKAGT-VNNNLCEHFAYSRQELFHLIRVEGIKTFEELLAKH-EVCKPTVGSLLASCWNEYILKPQHTPLQDTNDNFLANIQKDGTYSVIPRSAGGEITPEGLVAVGRIAREFN-TGSQRIGLRQLIEAGFETGHAYAKALSTWCRYGVGDSVGKGIRTPHKMKFGVSGCTECAEAQGKD-ATEKGWNLYVCGNG...... 710
51 -10.400[C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes  ali follow..  12  1................................................................MTKHYDYIAIGGGSGGIASINRAAMY------GQKCALIEAKELGGTCVNVG----------VPKKVMWHAAQIREAIHLYGPDYGFDTTINQFDWSKLIASRTAY------DRIHTSYDNVLGKNNVDVIKGIEVNGETITADHILIATGGRPSHPEIPGVEYGIDSDGSALPERVAVVGAGYIAVVINALGAKTHLFVRKHAPLRSFDPMISETLVEVMNAEGPQLHT----------------AVPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPSTDNINLAAAGVKTNEKGYII--VDKFQNTNVEGIYAVGDNTGAVE------TPVAVAAGRRLSERLFNNKPEEHLDYSNI............................................................................................................................................................................................. 339
52 -10.100[C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB  ali follow..  14  121..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TKCIQACPVDAIVGATRAMH-----TVMSDLCTGCNLCVDPCPTHCISLQPVA.......... 168
53 -9.770[R] COG2907 Predicted NAD/FAD-binding protein  ali follow..  10  2..................................................ASVALALWERVLANVVPRQSIAVIGAGVSGLSAAWLLSHR--------DVTLYEADNRLGGHANTFIVYNEPNYPNLTALFRHIGVETTETDMSFGVSLDGGALEYSVRFYREGRNIPADLEQGGLCRLDDYLRRQAAGVSGPILTGRPVKAIHRGPDGVRI-----------------EDATGETRAFDHVVIGDQALSMLAAPSAEERELLGAFRYSRNRAVLHSDPALMPRRRG-----------------AWASWNHVGRRGEDGEGGVTYWMNILQPLGVERPYFLSLNPMQDPAGLMHDQVYEHPLFDGPAMLAQRRLWSLQGRRTWFCGAGSGFHED--------GLQAGLAVAEQLGGV........................................................................................................................................................................................................ 426
54 -9.700[Q] COG3486 Lysine/ornithine N-monooxygenase  ali follow..  16  3.........................................................PTACTTPAGEILDVVGIGIGPFNLSLAALLAEAGYD-----RTVFLERKPYFSWHLLEGTTLQVPFLADL-------------------VSLVAPTSRFSFLNYLQAHDRFFENFHIPRREYDHYCQWVSGQL-PSLRFGSEVTRVDVVDGCYRVTARAG--------------NSESIHYAHNLVLGTGTQPWLPACL......................................................................................................................................................................................................................................................................................................................................................................... 170
55 -9.690[Q] KOG0405 Pyridine nucleotide-disulphide oxidoreductase  ali follow..  10  8..................................................DGEIDKVAADEANATHYDFDLFVIGAGSGGVRAARFSANH------GAKVGICELPFHPISSGVGGTCVIRGCVPKKILVYGATYGGELEDAKNYGWEI---NEKVDFTWKKLLQKKTDE------LRLNNIYKRLLANAAVKLYEGEGR-------GPNEVEVRQID-------------GTKISYTAKHILIATGSRAQKPNIPGHELAITSEEFPKRAIVLGGGYIAVEFASIWRGMATVDLFFRKELPLRGF-----VARNLEGRGVNLHPQTSLTQLTKTDQGIKVISSHGEEFV-LFATGRSPNTKRLNLEAVGVELDQRTNIPSIWAVGDATNRIN------TPVALMEATCFANTAF.......................................................................................................................................................................................................... 361
56 -9.680[O] KOG4716 Thioredoxin reductase  ali follow..  1...........................................................MAPVQGSYDYDLIVIGGGSAGLACAKEAVLN------GARVACLDFVKPTTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNV---DEKIKPDWHKLVQSVQNH------KSVNWVTRVDLRDKKVEYINGLGS--------------------VDSHTLLAKLKSGERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMALLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQKDKIPVDSQE---ATNVANIYAVGDII--------YGTPVAVLAGRLLARRLY.......................................................................................................................................................................................................... 350
57 -9.650[C] KOG2495 NADH-dehydrogenase (ubiquinone)  ali follow..  45.................................................KRILHADATLDSDGNPIRKKKVVVLGSGWSGYSFLSYLNN------PNYDVQVVSPRNFPLLPSVTNGTVEARSI--VEPIRGLMRKKGFEYKEAECVKIDASNKKIHCRSKEGSSLKGTTEFDMD---YDILILAVGAKPNTFNTPGVEEHAYFLKEAEDALNIRHSVIDCFERASLPNLTEEERKKILHFVVVGGGPTGVFSAELHLVQDVAKEAGDHILNMFDKRITAFAEEKFQRDGIDLKTGSMVVGVTAD----ISTKERETGKIVSEPYGMVVWSTGIGSRPVIKDF-----------MQQIGQGQRRVLATDEWLRVEGC--DGVYALGDTATINQRRVMEDIAAIFNKADKGNTGTLKKKDFNSVVKDICQRYPQV....................................................................................................................................................................................... 423
58 -9.310[C] COG1252 NADH dehydrogenase, FAD-containing subunit  ali follow..  11  2...........................................................VASLENHQPHEVVIVGGGFGGLYAAKALAK------TNVNVTLIDKRNFPLLYQVATGTLSPADI----------SAPLRSVLSKSKNTKVLLGEVNDIDPNLQQIIVGDKVV-----PYDTLIVATGAKHSYFGKDNWQELAPGLKTVEDAIEMRRRIFGAFEAAEKETDLEKRKALLTFVIVGGGPTGVELAGAIAELAYKTLQEDFRNINTSETRILLLQGGDRILPHIAPELSQAATTSLREFGVVVQTKTRVTSIENDIVTFKQGDELQTITSKTIAGVKASPMGKVLAERTGVECDRAGRAIVEPDLSIKGH--QNIFVVGDLANFSHPSVAP---VAIQEGEYVAKLIKKRLQGKTLPA................................................................................................................................................................................................ 354
59 -9.300[Q] KOG1399 Flavin-containing monooxygenase  ali follow..  11  1..........................................................MAPAPSPINSQHVAVIGAGAAGLVAARELRR------EGHTVVVLDREKQV------GGLWVYTPETESDELGLDPTRPIVHSSVYKSLRTNLPRECMGYK-PRGDDPSRDSRRYPSHREVLAYLQDFATEFNIEIRFETEVLRVEPVNGKWRVQSKTGGGFSNDEGKISKFSYTLFQKKLLVVVIGNFASGAISRDIS--------KVAKEVHIASRASKSNTFEKRPVPNNNLWMHSEIDTAHEDGTIVFKNGKVVHADTIVHCTGYKYY--------------------PFLETNNYMRVDDNRVEPLYKHIFPPALAPGLSFIG-LPAMGLQFYMFEVQSKWVAAVLSGRV---TLPSVDEMMDDLKLSYETQEAL................................................................................................................................................................................... 366
60 -9.100[F] KOG1800 Ferredoxin/adrenodoxin reductase  ali follow..  12  23.............................................................IQSTTPTKRICIVGAGPAGFYAAQLILKQL----DNCVVDVVEKLPVPF-----G----------LVRFGVAPDHPEVKNVINTFTKTAEHPR---LRYFGNISLGTDVSLRELRDRYHAVLL----TYGADQDRQLEL------ENEQLDNVISARK----NGLPGAENLAPDLSGRDVTIVGQGNVAVVARMLLSPLDALKTTDTTEYALEALSCSQVERVHLVGRRGPLQAAFTIKEKLPNVDTRWKLQRPRKRLTELMLKSLKEQGRISGSKQFLPIFLRAPKEAAVPTSSTERLPSHLILRSIGYKSSCVDTGPGLYVAGWLG--------TGIVTTMNGAFAVAKTICDDINTNALDTSSVKPGYDA....................................................................................................................................................................................... 422

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Comparative analysis of protein domain organization. Genome Res. 2004 Mar;14(3):343-53.