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Query: [I] KOG2468 Dolichol kinase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKTTATSFVTGERVVVFVVVSRILLSLPLSLISHGFSLFLLSLSAFLVEIRVETSPFLLSHFSSRRGASSGILLGAVTLPSVMISKLVQLSRAISIHEAEQDELAHVTMQYWAASASCCAILIYLSVIMSQVRKDESLSSSSIWLTRVSLTGTVLYGVACFVSLSMISHTGLNTSLKMLWMLFHGLAAVKLIRHLLCTFPSCASIGEALLVTSGLVLYFGDFLACTIAKIFEKLIPVDLVSISYGIKRTETGIIVQGLLLGLLLFPMVFRFVLHIYESSLRKRDARQRNCSDAAKSVLFFVSLLFFMVVAVPSWMQFVHDFNQHPFLWVLTFVFSEPLKRLSLCIYWILLIVVSVSRFYNISRSSKVERILLRKYYHLMAVLMFLPALVLQPKFLDLAFGAALAVFVALEIIRVSSLLLKEISFYFSLLSMGLMQDTHCENQIWRIQPLGEPLHQFMNAFTDHRDSEHLIVSHFSLLLGCALPIWMSSGFNDRALSPFAGILSLGIGDTMASMVGHKYGVLRWSKTGKKTVEGTAAGITSMMAVCFVLVPILASMGYILSQGWWSLLVAVTATGMLEAYTAQLDNAFIPLVFYSLLCLLast
1 -125.000[I] KOG2468 Dolichol kinase  ali  100  1MKTTATSFVTGERVVVFVVVSRILLSLPLSLISHGFSLFLLSLSAFLVEIRVETSPFLLSHFSSRRGASSGILLGAVTLPSVMISKLVQLSRAISIHEAEQDELAHVTMQYWAASASCCAILIYLSVIMSQVRKDESLSSSSIWLTRVSLTGTVLYGVACFVSLSMISHTGLNTSLKMLWMLFHGLAAVKLIRHLLCTFPSCASIGEALLVTSGLVLYFGDFLACTIAKIFEKLIPVDLVSISYGIKRTETGIIVQGLLLGLLLFPMVFRFVLHIYESSLRKRDARQRNCSDAAKSVLFFVSLLFFMVVAVPSWMQFVHDFNQHPFLWVLTFVFSEPLKRLSLCIYWILLIVVSVSRFYNISRSSKVERILLRKYYHLMAVLMFLPALVLQPKFLDLAFGAALAVFVALEIIRVSSLLLKEISFYFSLLSMGLMQDTHCENQIWRIQPLGEPLHQFMNAFTDHRDSEHLIVSHFSLLLGCALPIWMSSGFNDRALSPFAGILSLGIGDTMASMVGHKYGVLRWSKTGKKTVEGTAAGITSMMAVCFVLVPILASMGYILSQGWWSLLVAVTATGMLEAYTAQLDNAFIPLVFYSLLCL 598
2 -47.200[I] COG0170 Dolichol kinase  ali follow..  21  104........................................................................................................................................................................................................................................................................................................................................YILHVLDEIRQAPYAFVEIGCILLACLLAQ--VLLLRSPCTNLKRKTFHLFAFLVFYKEHR-------VSFLLAEGLLLFMSLL-----------------------------------SSCRYTNSLLRPFFSRNDKGRTLLSPIYLLSACMYPRLFI-----EDVEYVSALISICFQDSAASIAGKWFGVTE------KSIQGAIAGVISGTVVYFAL------------YGRIDMLPFFIFAGSVEYLVPINDNITIPLFAVLYFQA 306
3 -43.100[S] KOG4453 Predicted ER membrane protein  ali follow..  18  75..................................................................................................................................................................................................................................................................................................................................................SDVCAFGVTSIVAFSCLGFWGEIGKRGIFDQKLIRKLVHINIGLVFMLCWPLFSSGIQGALFASLVPGLNIVRML--------------------------------LLGLGVYHDEGTIKSMSRHGDRELLKGPLYYVLSITSACIYYWK---SSPIAIAVICNLCAGDGMADIVGRRFGTEKLPYNKNKSFAGSIGMATAGFLASVAYMYYFASFGYIEDGMILRFLVISIASALVESLTDIDDNLTISLTSALAGFL 305
4 -14.000[I] COG0575 CDP-diglyceride synthetase  ali follow..  12  2..................................................................................................................................................................................................................................................................................................................................................................................KQRIITALILAPLVILGILYLPFAWFMLALAVVTLLGFWEWTQFVNQPSRMLAMIPALLVGGISVALIDFQFPAISNMNTAHFIVLGIGSL--SSTVRHLFGLFTLLPFFWSVLFLRADTYLSDKLVLFVCFLVWAADSGAYFVGKSLGKHKM--SPNKTIEGLVGGIVTAMLVGYWVAECFGIQFSSMPVMLLIILLTVVISVLVESILDRIDSLTAPVFALLY... 277
5 -13.900[R] COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase  ali follow..  13  11....................................................................................................................................................................................................................................................................................................................................................CLGGIFSVLLLATIIIFVLKKCRPQRDWLELQQRINSWWVIICLFSLAMLSPKWLALTFFGFISFLSLKEYLTLAPTRRSDSVPLLWMYAAIPLQYVWIGMSWYGMFIIFIPIYVFLFLPA--HSASIMHWGMMATVFALSHVAYLGVDAKAGALLVIFLVVATELNDISQYLWGKSLGKIKV--SPNKTLAGLLGGVLTTMLLAAIFGPLLTPMDWLHSLGAGVIILSGFCGDVVMSILDRLDSLIYPLFFHFYHYF 307
6 -10.100[I] KOG1440 CDP-diacylglycerol synthase  ali follow..  14  42..........................................................................................................................................................................................................................................................................................................................................................................DRNKYKSFMVRTYSTLWMIGGFVLVVYMGHLYI-TAMVVVIQIFMAKELFNLLRKILSQRLANTMTADQFFYRLVSGLIKYHMAICYLLYIIGFMWFILTLKKKMQYAWTHMILIVVFTQSSFTVANIFEGIFWFLLPASLIIINDIFAYIFGFFFGRTPLIKLSKKTWEGFIGASVTTIISAFVLANILGRFPWLTLPVQWHALCLGLFASII-GITDRMDCQMVVFAYIYLQSF 377
7 -7.500[S] COG1836 Predicted membrane protein  ali follow..  13  1...........................................................................................................................................................................................................................................................................................................................................................................................................MIVLALLGVLLLSVYAYKTKKLTLSGAISAFVVGALISFGLGFKGLLLLAIFFFTSGFWSRFYQ--STRDGWQVLAN----GFAAICALLFSILQDPIYICGFVASLAAANADTWASEVGPLAKRRPIHIIKWKSAIGTAAAFAGSFIIVVVSIFFWWSSSFASHHLLFSLTLAGFLGNLFDTLVGALNNDTVNAICTGTGAL 252
8 -7.350[P] KOG3684 Ca2+-activated K+ channel proteins (intermediate/small conductance classes)  ali follow..  10  279.....................................................................................................................................................................................................................................................................................................KRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLAL-----KCLISLSTIILLGLIIAYHTREAQLFVIDNGADDWSLEMLVCAIHPIPGEYKFFWTALSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTMTICPGTVLLVFSISLW--------IIAAWTVRACNFLGAMWL----------ISITFLSIGYGDMVP-----------------HTYCGKGVCLLTGIMGAGCT-----------------ALVVAVVARKLE--LTKAEKHVHNFM....... 559
9 -7.270[P] KOG3713 Voltage-gated K+ channel KCNB/KCNC  ali follow..  14  227.....................................................................................................................................................................................................................................................................................................................................................TACIGWFTL-------YLLRLFSSPNKLHFALSFMNIVDVLAILP-------YVSLTLTHAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLA--VGIFVFSALGYTMEQSHPETLFKS-------IPQSFW-----------AIITMTTVGYGDIYKTTLGKLNAA---------FLCGVIAIALPIHPIINNFVRYYN............................................. 414
10 -7.120[P] KOG4505 Na+/H+ antiporter  ali follow..  10  1MAWSQVEISKPHLAYAIIGGFTSLFMLCSLIIKEKLFLGEATMATAT-----------------------GLIFGPYVAKLFVPTSWGNTDY---------------------ITEELARVLLVVEVFAAGAELPRAYMLRHWRSMFVMLLPVMIFGWLVSTGFMYALIPRLSFLESLAIAACITATDPVLASSIVGKGKFARRVAESGC-NDGMAIPFLYLAIYLIIE------KPARHAGRDWVCIIILYECTFGCVLGAIIGVIARKMIKFS----------ERRGLMDRESFLVFYFVLALFCGGIGTII----------------------------LLVSFCAGAAFSWDSWFSKKTEESHVSNVIDLLLNLSFFVYVMPWPQFHMPHMDLSVWRLVVLAICILIARRI--------------------------------PAVLLFKSFVPDIINWREA---------LFAG------------------HFGP-----G--VGALYTCLVARAELEVHSTVPEPNDAIENPEIPNWYCI-------------QVMWPVVCFLVLSSII------VHGSSIAFFM...... 435
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.