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Query: [R] KOG2563 Permease of the major facilitator superfamily, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGADDGAISADKVDIRLQPLNKNGAQDETDEEAADQIQLRVYKQRWIVLLAVALLNNTNTMSWIGYAPSGNYVNSFYGESSAAWLSMVYMMCTIPVGMFAMWAGREWGLRTAVLIAGWANGIGAVIRVISSLDFVPQDLRFPICMTGQGIAAIAYPFIMFLPTKVAGSWFPDTQRAIATSIGVMSNPLGVLMANLISPAIVKSPEHVIWLNIFTCVPSLIAMLIATFGVNRSEPKIPPTFSASKPQMDFVSGMKSCFSSKQYIILLIVMGGGIGMFNCLYTVMLELLCPSGYSNFFSGVCAALMIVGGVFGAAASSIFVDRTKLYEETLKIALGAAVIFGLIFLQLTLHQGYSVILGVTCLLFGVLGLATYPIGLELASECTFPVSEATSTGLIVLSGQIQSVIYVFIMKNFARPLQPDRMHIQVCQLTPDDTINTPKDNTMSIMIFSLLATLLVLTLVVLFKPVYKRLEAERGNRATADKAKELSNQNKDRITLQAESAVEPLQKKLast
1 -131.000[R] KOG2563 Permease of the major facilitator superfamily  ali  100  1MGADDGAISADKVDIRLQPLNKNGAQDETDEEAADQIQLRVYKQRWIVLLAVALLNNTNTMSWIGYAPSGNYVNSFYGESSAAWLSMVYMMCTIPVGMFAMWAGREWGLRTAVLIAGWANGIGAVIRVISSLDFVPQDLRFPICMTGQGIAAIAYPFIMFLPTKVAGSWFPDTQRAIATSIGVMSNPLGVLMANLISPAIVKSPEHVIWLNIFTCVPSLIAMLIATFGVNRSEPKIPPTFSASKPQMDFVSGMKSCFSSKQYIILLIVMGGGIGMFNCLYTVMLELLCPSGYSNFFSGVCAALMIVGGVFGAAASSIFVDRTKLYEETLKIALGAAVIFGLIFLQLTLHQGYSVILGVTCLLFGVLGLATYPIGLELASECTFPVSEATSTGLIVLSGQIQSVIYVFIMKNFARPLQPDRMHIQVCQLTPDDTINTPKDNTMSIMIFSLLATLLVLTLVVLFKPVYKRLEAERGNRATADKAKELSNQNKDRITLQAESAVEPLQKK 507
2 -60.000[G] KOG4686 Predicted sugar transporter  ali follow..  10  1MAREDEERIVDNEEVSRPTEEDQVVSRAGRRDNELSLP-SSTSHRFMALVFMCLLGFGSYFCYDAPGALQNYFKKDLNLTQFTLIYSIYSWPNVVLCFVGGFLIDRLFIRLGTIIYMMILLVGQLIFACGGIL-----DAFWMMILGRFIFGIGAESLAVAQNSYAVLWFKGKELNMVFGLQLSVARFGSTVNFWVMQPIYEYVSNFYKGHTALGVVLLLATLTCVMSMTCAKRAERILQRNNNPAGQIPKLTDVFSFKPPFWMVSIICVAYYVAIFPFIALGQNFFVDFGLSPAEANTVDSLVYLIAAVSSPVFGFIIDKLGRNVTWVFTATLTTIGAHALLTF------TQLTPYVGMIIMGLSYSMLAASLWPLVALIIPEYQLGTAYGFCQSIQNLGLAVITIVAGIIVDHSGGEHMWLQL------------------FMGWLTIALISTGVIWAYNNKNRGNLNMTPQQRAQFVSAENYQNFE.................. 478
3 -51.500[G] COG2271 Sugar phosphate permease  ali follow..  8  6.......................KPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWA----TSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVASAIVGYTVDFFG-----------------------WDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQERNGG........................... 452
4 -46.200[P] COG2223 Nitrate/nitrite transporter  ali follow..  11  2............SHLSAPERATGAVITEWRPEDPAFWQQRGHRVASRNLWISVPCLLLAFCVWMLFSAVAVNLPKVFTTDQLFMLTALPSVSGALLRVPYSFMVPLFGGRRWTAFSTGILIVPCVWLGFAVQ---DTSTPFSTFIIISLLCGFAGA-NFASSMANISFFFPKQKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAAFGSHGVEQPDGSQLYLANAAWIWVPFLAIFGMNELATSKASLKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAGFAMLSKTQ-FPDVQILHYAFFGPFIGALARSAGGAISDRLGGTRVTLINFVLMAIFSGLLFLTLPTVGGSFIAFYGVFLALFLTAGLGSGSTFQMISVIEAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGS----------------------PVGAMKVFLIFYIACVVITWAV---YGRHSKNKK................................. 465
5 -42.200[P] COG2807 Cyanate permease  ali follow..  13  2..................................TCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAYSLTQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSP---------YLLFGGTAVIGGGIALGNVLLPGLIKRDFP-HSVARLTGAYSLTMGAAAALGSAMVVPLALNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRAL--------HTRGIWRSPLAWQVTLFLGINSLVYYVIIGWLPAILISHGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQRGIAAFVALMCAVGAVGLCF------MPAHAITWTLLFGFGSGATMILGL-IGLRASSAHQAAALSGMAQSVGYLLAACGPPLMGKIHDANGN----------------------WSVPLMGVAILSLLMAIFGLCAGRD.......................................... 389
6 -36.800[U] KOG3764 Vesicular amine transporter  ali follow..  7  48LYSIKHEKNATEIQTARPVHTASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFS--------SSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTP----------LTTLLKDPYILIAAGSICFANMGIAMLEPALPWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWL-----CALLGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLV-VSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIG-----------------------FPWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAILMDHNCPIKTKMYTQNNIQSYPIGEDEESESD. 514
7 -33.100[G] COG0738 Fucose permease  ali follow..  10  2.........................ATSIPTNNPLHTETSSQKNYGFALTSLTLLFFMSGFITCLNDILIPHLKNVFQLNQSMLIQFCFFGAYFIVSLPAGQLVKRISYKCGIVVGLIVAAIGCALFIPAAS-----YRVYALFLGALFVLASGVTILQVAANPYVTILGKPETAASRLTLTQAFNSLGTTVAPVFGAVLILSAATDATVNAEADAVRFPYLLLALAFTAIIFAILKPPDVQEDEPALSDKKEGSAWQYRHLVLGAIGIFVYVGAEVSVGSFLVNFLSDPGLSETDAAHHVAYFWGGAMVGRFIGSAAMRYIDDGKALAFNAFVAIILLFITVAT------TGHIAMWSVLAIGLFNSIMFPTIFSLALHGL---SHTSQGSGILCLAIVGGAIVPLIQGALADAIG.......................................................................................... 387
8 -33.000[G] COG2814 Arabinose efflux permease  ali follow..  11  2.....................TANVTTVPQDDSETPNEAPAQVASWSGVFAMSVCAFALIASEFLPVSLLTPMARDLQVTMTGQGIAISGAFAVLTSLFISALAGSLNRKTLLLGLTLAMGVSGAIVALAP--------NYAIYMLGRALIGVVVGGFWSMSAATAIRMVPKRDVPRALAIVNGGNALATVVAAPMGAYLSTVIGWRGAFLCLVPVSLIALAWQWKTLPSMPAAARAPGIGQ-------VFKVFTLFKHPGVVVGMLASSLLFGQFGLFTYVRPFLETVTNVHGATISLFLLVLGAAGFIGTVLIGRVLQRSFYQT-----MIVIPVLMALTALALIAFGSSVAIVLVLLALWGLTGTSAPVGWWAWIAKVF-PKDAEAGGGLFVAVVQMSIALGSTVGGILFDHSG-----------------------YRTTFVASAVLLAICAVLTVVTARQSASH...................................... 408
9 -32.600[G] KOG2532 Permease of the major facilitator superfamily  ali follow..  10  1........................................MQMNT--LTLNFTVICMDDIVEDFHMFHNSTETHWFERSTEKSLLFSGVAIGGLIGLVPSVPQISSIGLRNTQTISGFISGLGSFL------FPLAVSVGFYTSFLCRVLQGIGAAVLFTAVGVVPGVWAPKSEANTFMSILACAFQLSNVICMPVSGLLCESAVGWRSIYYISGAITFVLYTVFWFTYTDDPKLHRNVSQKEVEKIKEPVPYFAVSTDPTVIISWISFGGNMGFYVLCIYGPTYLREVLKFDVKETGFLTALPFILSAIAKFSAGRISDKLTGLSERARFFFASIFQIGLVAGLVVMAFTTNRVIAQIAFNFAIVSSGLNIMGVVKFADLP-KNLIFVNLPICQFAGSFREILYKIETLKVRCLQHVHYTLTVMSFTAYASQFLSPEQWKTFFLVISGLIVACNAGFPFLARSDAAGYTKKQEPTVK............................. 451
10 -31.000[P] KOG0252 Inorganic phosphate transporter  ali follow..  9  2.........................AKKGKEVLNALDAAKTQMYHFTAIVIAGMGFFTDAYDLFSISLVTKLLGRIYPPNVAAAVNGVAFCGTLAGQLFFGWLGDKLGRKKVYGITLMLMVLCSLGSGLS--FGHSANGVMATLCFFRFWLGFGIGGDYPLSATIMSEYANKKTRGAFIAAVFAMQGFGILAGGIVSLIVSSTFDDYVWRIVLMFGAIPALLTYYWRMKMPETARYTALVARNTKQAASDMSKVLQVDLIAFLLDIAYYSSNLFQKDIYTAI-AETMNAIHEVFTVSKAQTLIALCGTVPGYWFTVAFIDILGRFFIQLIFMTIFMFALAIPYDHWRHRENRIGFLIMYSLTMFFANFGPNATTFVVPAEI-FPARRSTCHGISAASGKAGAIVGAFGFLYAAQSSDSEKTDAG----------YPPGIGVRNSLLMLACVNFLGIVFTLLVPES-KGKSLEEISREDEEQSGGDTVVEMTVANSGRKVPV...... 542
11 -28.500[R] KOG2325 Predicted transporter/transmembrane protein  ali follow..  9  5.................TDSPIVHDGILLEKEQLMNKDKDDRLTNWRLIITAAVVSCLNAVENSVLGIGEWPYMREIDPNAFGLATSASKCGHAVFALIFSIWSYKTSVKIPLIASRLIAIAACMIYLTI---EYVKTDKRYVLMAVYTLLGIANSGGTVLRGYVTLC--SNEDRPRAFAALGLSFIFSIIVGPTIQLIFSAWFHLYSAPIWISFILTILTVFVILILIEDISREKKTKLRPSESQSSFSMERWR-LDWKLIVVCFFVRMAVSFSHSTLSTIGSILYMVFGWDGATTVRVSITMVIFGVMSSTILLLYIFCHFGKILPQHKVFLFFTIAFGAVYIIALAVNPMLYLSVTILVAGMSIPIMSTALDTVYSRILGNIDQSVAHGAMAVIDDILYMITPIFTTTMFTLYGIGPL-----------------------IVKSMAFGIIALTVLVSGQ............................................ 484
12 -28.200[S] KOG3097 Predicted membrane protein  ali follow..  9  1MTGFTNAGFENDEPVKPKAGFEPDTASLREKVVLNPGEKWRILKN---ISIISIAFMVQFTAFQGTANLQSSINAKDGLGTVS-LSAIYAALVVSCIFLPTLIIRKLTVKWTLVCSMLCYAPYIAFQLFP---------RFYTLVPAGILVGMGAAPMWASKATYLTQ--VDAIIVRFFGFFFLAWQSAELWGNLISSLVLSSGAHGEISMIYLSCIVAAVCIIAFFLDPLKRYGEKRKGSNSAAELSGLQLLSRQMKKPNLQLLIPIT-VFIGMEQAFGADFTQAYVACALGVNKIGFVMICFGVVNALCSILFGSVMKYIGR-TPIIVLGAVVHFTLITVELFWRPNPDNPIIFYAMSGLWGVGDAVWQTQINGLYGLL-FRRNKEAAFSNYRLWESAGFVIAYAYATTLC---------------------------TQMKLYILLAVLTLGCIGYVIVEILYRKKQRKLKKQEKLEAAEKEKEAAAAAAAAALAAAEAGADG. 518
13 -28.100[G] KOG0569 Permease of the major facilitator superfamily  ali follow..  10  8.............................................ILSIALCLSSGFQQGYIASVLNQPYAQIEQFINSS-WSLLNVCFPIATIFGQFLAGWMCSQFGRKHTALIASFLYIPGALLCAAAKWCF----PAFELLFVGRIIWSLANGVNTVNATVWIVECAPPQIRGRMAAMQEFFMALGSLLTQAVGVPFSTDELWPYNFLPNCAVVVVSMVMFSWV------AESPQFIMEKYNDVDRARKALAQYHGVSWVGVMVKIAYVFTGARSLRGYSTFILYTLSFTYSQATWLSFATGLLRLPFTLVPVFLVDRLGRRPLIIVMLVSFVSILVMIIAININGELKYATFIGLTVLLLVNTCGIGSVSRFYAAELVPRNLLLSSVSTLTMFEALTKIGVEFAFYPTANVIG-------------------------QSLLLFLIPTGVFTVMCYLMCPETSRMTVNE.................................. 477
14 -25.600[P] KOG3574 Acetyl-CoA transporter  ali follow..  9  28.GPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKVSYTDQAFFSFVFSLKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLDRTPDVIALTVAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFALLKKENEVSVVKEETQGITDTYKLLFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDAVELVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGSSSWKCKRNN........................ 549
15 -24.500[R] KOG0254 Predicted transporter (major facilitator superfamily)  ali follow..  9  1..............MLISIFKSGIFQWQYRRQLLVSLSEMMMSCADLNVLVATLITFCHGIALGWLSPMLPKLLS-IDVNEASWLGAVISIGGISGNFSFSYLMNRFGRKVSIYALAVPH------------------TSIEWLYVARVFAGLTGGGMFVVLPIFIGEIADNSIRGRLCSFFTLTMNTGIMVGFVVSSHI-------AYHVIPCAVVGLPVLYVLLATRYPEPPQQLIRWKREEEAEKSLRYYRRCSLKALATGLVLMVANIFTGTFAFNNYMSNIFDAVHTQ--DPNTNTIIIGAVQILGTLASIYLVDRYGRKILLIVSCAGSGIGTSAFGLYAFYAEEQKLPVTLMAFIIFIANVGVISVTMVVLVEILPQKIRAVATSFCLGCLSFFAFASLKTFPLMMFHLG-----------------------LAATMWFCAAVSVICLFYVVVCLEETKGRSMYD.................................. 472
16 -24.200[R] KOG2816 Predicted transporter ADD1 (major facilitator superfamily)  ali follow..  8  1........................................MEVFRLGELRHLLVTVFLSGLAEYLIRPVMTDVTVAAVCSGTGVQQVTVGMGTMVMMPVIGNLSDRYGIKAMLTLPMCLSVLPPAILGYRR--------DTNFFYAFYVIKTLF----------DMAKNVHGTKRISMFGILAGVSSISGVCASLSARFLSIASTFQVAAISLFIGLVYMRVFLKERL--QDADDDDEADSGGCRSHQEVHNGGDLKMLTEPILRDAPTKTHVFNSKYSSWKDMYFLKRFGFNKNDFAELFLLVTIIGSISQLFILPTLSSTIGERKVLSTGLLMEFFNATCLSVA-----WSPWVPYAMTMLVPGAMFVMPSVCGIASRQVGSSEQGKVQGCISGVRAFAQVVAPFVYSPL---------------TALFLSENAPFYFPGFSILCIAISLMIGFLQSLLIKDHPSLPLVNITINNPSKAEA........................ 415
17 -23.500[R] KOG0253 Synaptic vesicle transporter SV2 (major facilitator superfamily)  ali follow..  10  2.......................ADGNTRFTVDEALVAMGFGKFQIYVLAYAGMGWVAEAMEMMLLSFVGPAVQSLWNLSQESLITSVVFAGMLIGAYSWGIVSDKHGRRKGFIITAVVTFVAGFLSAFSP--------NYMWLIILRCLVGLGLG--GPVLASWYLEFIPAPSRGTWMVVFSAFWTVGTIFEASLAWLVMPRLGWR---WLLAFSSVPSSLLLLFYRWTSESPRYLILQGRKAEALAILEKIARMNKTKRTLLLWVVFFGNAFAYYGVVLLTTELNNSHNRCYPTEKQLRFIASFAEFPGLLISAAMVDRLGR-----KASMASMLFTCCIFLLPLLSHQSPFITTVLLFGGRICISAAFTVVYIYAPEI-YPTARTTGVGVGSSVGRIGGILCPLVAVGLVHGCHQTIA-----------------------VLLFEVVILVSGICVCLFPFETSGRDLTDSISASKEPPSAS...................... 499
18 -23.200[G] COG2211 Na+/melibiose symporter and related transporters  ali follow..  7  20...............................................................FAIGIVYMYLMYYYSVGLVGTLFLVARIWDAINDPIMGWIVNRWGFKPWILIGTLTNSLVLFLLFSA--HLFEGTAQVVFVCVTYILWGMTYTIMDIPFWSLVPT--DKREREQLVPFPRFFASLAGFVTAGITLPFVSYVGGADRMFTLVLIAFFIASTIVTLRNVHEVYSSDNGVTAGRPHLTLKTIVGLIYKNDQLSCLLGMALAYNIASNIINGFAIYYFTYVIGDADLFPYYLSYAGAANLLTLIVFPRLVKMLSRRILWAGASVMPVLSCAGLFAMALADIHNAALIVAAGIFLNIGTALFWVLQVIMVADTV--RCESIAYSVQTMVVKGGSAFAAFFIALVLGLIG-------YTPNVAQSAQTLQGMQFIMIVLPVLFFMMTLVLYFRYYRDMLRKIQIHLLDKYRKTPPFVEQPDSPAISVVATSDV....... 474
19 -23.000[S] KOG3098 Uncharacterized conserved protein  ali follow..  9  33..DQEPTNLSGIENCAKAREMRQGTESASTIYLILYSAFMIILFNFSKFPKFYAVTNVILGQKMPKSFVLESVIHSIHERTPKAIGAVMYIIYMIGCLFSPSILNEIGAKYILICSAICFASFPLGFFFV---------NSYYYYFSQMLLGFGYALYYQGHGGYLTSHSTRKTIESNINIAWCVGCICLLLSSGILATVTHMTLDSLEIKLLFGVFLGASVLGIVNFISCPGKDVTNCIQETKKKGTFMEGFKSALTSKSMLQLFPLFGTSSSFWLSIFTTAMNFTAANSNLTYLAAIYPLSVGVGEIGTALFITQMSRRFKDFSLQPTMLIGAIFSILGFGLVHVSTPYSYLVISVIGVIVGIGDCCLNSCRSVI-CALAMPDRRAQAFSISKLYQALGSCVLFFASPII---------------------------PLYVYTIGVSIHLIIANVFFNITARRTQTMEKDMQ................................. 519
20 -22.600[G] KOG2533 Permease of the major facilitator superfamily  ali follow..  10  39.QFSTTVIDSSDLNVFNDGAETTVKEQEFTSSELRRLQKLRLKMDLRIIPCLWILYFLSCCLRFTVSLSFIQTLSGYSAHYLALGLALFYVGYIIFEVPSNLMMAFIEPR--IWVSRIQLTIGVVGACHAVLG--TKHGNAQSYVALRFFLGVAESGLWPGLAYYMSRWYRGKHLGKRIGWYYTAAQIAAAAVSLVSAGFQKMDG---QWMFLIWGVVAIAQALSIPWWLPAVASKEHRAEMNVGKRWQWSDLLKSCLDLRVWPFILMYFGIVGVGNGIFNYCTLIIEEINFSGIDISLLNAPIWLADALGIVTVMPLYDRFHKKFSFFTGSCLIIIAGLAVANYA----PRAWSRYGGLLMIGFGLGPTVPICMAWCSASM-DVGVASSLALVTGLGNLGSVVTTYALYSGWPGDPTFRKSNDVC------------------IALIGVSIIACGIEFLLDKTGFGQFNASFNNHDHEVEDEQEMTDIKPALPSSQQAD....... 567
21 -21.900[R] KOG0255 Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily)  ali follow..  9  60.SCSESSTDSDSSGSQIEKNDPFRVDWNGPSDPENPQNWPLLK-KSLVVFQIMLLTCVTYMGSSIYTPGQEYIQEEFHVGHATLNLSLYVLGYGLGPIIFSPLSERYGRLNLYMVTLFFFMIFQVGCATV--------HNIGGLIVMRFISGILCSPSLATGGGTVADIISPEMVPLVLGMWSAGAVAAPVLAPLLGAAMVDAKNWRFIFWLLMWLSAATFILLAFFFPETQHHNILYRRALKLRKETLYRPLKMIIKEPAILAFDLYIAVAYGCFYLFFEAFPIVFVGYHFSLVEVGLAYMGFCVGCVLAYGLFGILNMRIIVPRFLIVAMCVCWCLPLSLFLFGWTARVHWILPVISEVFFVLAVFNIFQATFAYLAT-CYPKYVASVFAGNGFCRASFACAFPLFGRAMYDNLATKNYPVAWGS----------------SLVGFLTLGLAIIPFILYKYGPSLRTRSSYTEE............................... 548
22 -21.500[Q] KOG3626 Organic anion transporter  ali follow..  10  6..............................................IFLGLFSFVFFLEAIGGSYINSAVQNIERQFQMSSSGFMISASDFGYIPCVVFIAHFGSKGNRARWIGAGAILVSITYLMLASKCKEQTSNSYPFLVFFFSLLLLGIGRTVPWSLGVPLLDDNIKKKSLPAYFGAISSIRVLGPICGYMIGSFCNKFYYTLNPFLFIGSIALFPSTMLFFFPQGKEGDGSAVQLRDVHKEKDFAKSCKKVLSTKIYMGSVLGRVCDVLAFKGYIVFLPKYLEHFGIPQYLVHRYAMFGVFGFGLGVATGGYVTKKLKLNGRRAAMFVMLMSTLNVCLYSGKIFKTSSVIFFLTVLPGSFVAGLGVVPAMLILLRSVPPETRSLSLGLQGMAVSLFGTL-PILWGLVIDAA-----DKACNGARGSCSIYHPDRLRVWMHLLYVVIRTVALITDVYVWKHAKNLNIMDEPVSEEKDNIRRNSIKMQAVQPDQ.......... 744
23 -21.100[R] KOG2615 Permease of the major facilitator superfamily  ali follow..  10  13................................................LFTVWIIVLCTALPISSLFPFLYFMIDDFNIAKAGFVGCSFMLGRAFTSVAWGLVADRYGRKPVILIGTASVVVFNTLFGLSL--------NFWMAIITRFCLGSFNGLLGPIKAYAMEI--RDEYQGLALSAVSTAWGIGLIIGPAIGGFLAQPAKQYPSLFLAISVFAFLVTIVSSRIPETLHNLKDLSDDPESNKVAERNGKSSLLNNWPLISSIIVYCVFSLHDMAYTEIFSLWANSLGYSTADVGSVLAFSGFGLLIFQLSLYSYAERLLGPIIVTRISGSLAMVVLSCYPLIAKLSGLAVTVTSASVAKSVLGTSAITGLFILQNKAVRQDQRGAANGIAMTAMSLFKAIGPAAAGII............................................................................................... 409
24 -21.000[R] COG2270 Permeases of the major facilitator superfamily  ali follow..  9  2...........................TVPSQNAETVVAKRGIWGWVMF---PFFTVVTTFIFGPYFVARLTDDPISAQATWSNMATVSSIIIALFSPILGSIADQSGARKPWIAFFAVIKIVSLFFLWFAAPGSPIILPIICMILASIAAEFSIVFNDSMMPRLT----NPQNVGRISNLAWGLGYLGGMVVLIAVVTLLASNPQARITGPLAALWYLVFILPMFLLTSDAEKGLPFAAAIRSGLGELKITLRELRYRPVLLRFLIARMLYQGVNGVIILGGAFAAGMFGWATMEIGLFGILLNVVAIAGCFAAGRLDQKLGSRITILISLALLLLATVGIVST-IFATGAEKAYLLYGVLIGLAFGPVQASSRSYLARNITVAEAGRYFGIYALSGRATSFMATLSFSIATTISGS----------------------AHIGMATLIVFLGAGFLLLLRVPER.......................................... 455
25 -20.200[E] COG3104 Dipeptide/tripeptide permease  ali follow..  9  1MTVGASQQTSTIALHNDTGMLMSNLNIFKQPNA------------------FYLIFSIEFWERFGFYGMQAILTVYMDESASFVLFGAFSALVYGFVAIGGWIGDKVGTKRAITLGAIVMMVGYVL--LGLSTADHPLVGPTLIYIAMGFITVGNGLFKANPSSLLAKIYPENDLDGAFTMYYMAINLGSFFSMIITPLVAIKMGYGMAFGVSAVGLAITVVNFLFCLRMLKGTGSPADSMSGIERAKMLVAFILMLQGVVFFVLYFQMPTSLNFFAI--NNVEHHIFGFDVAPEQFQALNPFWIM--IASPILAATYGKLGDKLAMPFKFAFGMALCALSFLVLSWGTLFSSNWLIASYAFQSIGELLVSGLGLAMVAQLVPQRMMGFAMGMWFLTSASAAVIAGWVASLTSTPANVSGATESLHIYGE-------------VFAQIGYVTAGIAIVTFMIAPKLTRICRGESEPLELVTQ......................... 514
26 -20.000[H] KOG3810 Micronutrient transporters (folate transporter family)  ali follow..  9  6.....................PVSRRAAAAAATVLLRTARVRRECWLPTALLCAYGFFA-----SLRPSEPFLTPYLNLTEREVFNEIYTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYA--------QGLLAIQFLEFFYGIATATEIAYYSYIYSV-VDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGEMT---LSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIAFQIAANL-----SMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEI------------TTQFLIYASYFALIAVVFLASGAVSVMKKCRKLEDPQSSSQVTTS........................... 497
27 -18.600[G] KOG4830 Predicted sugar transporter  ali follow..  9  22..........................................................................................................YGV---MLNDITASCWFTYLLLFLTQIGLSPRDAAIVMLSGQVADAFATIFTGELVDEYGLLWH--SMFAAIFNIGWAATQVANLGLYAIALVVFAGSKEDTETQYRWIAYSSITIGCCFVVIFLMGTKEPRLRIDLKETSRARIPWVYWFRKILYYQVAMVYLLTRLVLNVSQAYLAFFVIDLQMDQSAKALVPAIIYICSFVVSVLLQEIPWNGKRLKAYYTAGGIIWIFCGAAILLL--PRDISSFMYAISVFIGIANALMMVTAISMQSVLV--GGCAFVCGSLSFLDKMSCGLALYVLQSHQTTSPRGQLNNNQQSVYLSVTRYG-------LGLVPALCSFVGVAVTFFMELEAAGSLSKPLLRDR............................. 436
28 -18.000[R] KOG3762 Predicted transporter  ali follow..  8  2.........................ENHVGERTVNIFGKVFPRD----AFICRLFYLSFFASFGSLFPLLAVYFKQLGMTQAGFLIGSRPIVEFLSGPFWSQFASRFRKQKLLLLFSLGSLVLFTLGIGLVQPVTPYEQAFMLLLILICLCEFFSAPALPLADAATLHSV--RDNPAEFGKIRLMASVGWGFAMFIMGIALDYSDNYTLCFVMCVIFMLAAMGLASKFKFDDDVPAPGESEGGGGSENSLLLAMKALASMHILLFFVSVVVMGGGAGLVFSFLYWHLQDIGGSPVLFGILSVVNHASEIITYFYVFKLINKY-GHVRVMYLCLAVNFFRFMALSIL----DNPWMVLPLQILQGACLATVWSCASSYISLVAPPHAKQHAQYALQVGYHIGKGLGSIIGGSVISIIG-----------------------TRTTFVIYGLICLATCAGSFGLNKLFKYEGIKYGAGNFEEEDMDIMAPQGVPMARDGKITDAFNATT 603
29 -17.600[GEPR] COG0477 Permeases of the major facilitator superfamily  ali follow..  12  12...............................................VALASMVGTAIEFFDYYIYAAAAVLVTQFFHSDDSNDLLSTLALAFFA-SALFGHFGDKIGRKKTLVASLVLMGGSTVVIGLLPNYAQIGIWAPILLCVCRVGQGIGLGGEWGGAALVATENAPEGKRAWYGTFPQLGAPIGLFVANGTFFLVSYLLGHNALVE--IPFVSSILLVAVGLYVRLTLHESHVFVEAEQKGKKLNAPVSVVFTKKPMVIGTFIMVATYSLFYIMTAFAQAYSRTAGIPANTFTGLLLISAIVFGIFISISGFYADKIGRRKWLIWVTIAIGVLGLAMPLFL--ENGTPVSVFAFLVIGMAIMGMTFGPMAALLPELFPTEVRYSGASLYNLASIIGATIAAMISLKINASFGVMGVG-----------------------IYLAINALMTFLALLASKETKNV....................................... 433
30 -16.100[G] KOG0637 Sucrose transporter and related proteins  ali follow..  9  1MGALEAERAANNATALETQSSPEDLGQ---------------PSPLRKIISVASIAAGVQFGWALQLSLLTPYIQLLGIPHSSYMWLCGPISGMIVQPIVGYHSDRFGRRR-IAAGVALVAVSVFLIGFAKLENKVRTRAIIIFLTGFWFLDVANNTLQGPCRAFLADLAAGDKTRVANACFSFFMAVGNVLGYAAGSYFTMTKACDIYCANLKTCFFLSITLLLIVTFSSLWYVKDKQWSPPQGDKEEKTSSLFFFGERPMVMLLIVTVINWIAWFPFILYDTDWMKLYDQGVQAGALGLMFNSILLGFVSLGVESIGRKMGGAKRLWGCVNFILAIGLAMTPLAGPSSGIKAGVFSLFTVLGIPLAITYSIPFALASIFS-GAGQGLSLGVLNIAICIPQMIVSFSSGPLDAQFGGGNL---------------------PSFVVGAIAAAVSGVLALTVLPSPPPDAPAMSGAMG............................. 510
31 -15.800[C] COG3202 ATP/ADP translocase  ali follow..  8  18......................................WPIEQYENKKFLPLAFMMFCILLNYSTLRSIKDGFVTDIGTESISFLKTYIVLSAVIAMIIYVKLCDILKQENVFYVITSFFLGYFAL-VLYPYPDLVHPDHKTIESLSLAYPNFKWFILWGTMMLSLLFWTKIAEAKRFYSMFGLLANLALPVTSVVIGYFLHEKTQIVAEHLKFVPLFVIMITSSFLIIPRLYDPALVKEKKTKAKLSFIESLKMIFTSKYVGYIALLIIAYGVSVNLVEGVWKSKVKEL--KEAYTIYMGQFQFYQGWVAIAFMLIGSNILRKVSWLTAAMITPLMMFITGAAFFSFIFFDSVIAVMIGMIQNVLSKGVKYSLFDATKNMAYPLDQAAVEVIGGRLGKSGGAIIQSTFFILFPVFG--------------------IEATPYFASIFFIIVILWIFAVKGLNKEYQVLVNKNEK................................ 498
32 -14.300[R] KOG3880 Predicted small molecule transporter involved in cellular pH homeostasis (Batten disease protein in human)  ali follow..  8  1........................................MSDKSHQIYCYFWLFGLINNVLYVVILSAAVDIVGPTLPKSLVLLADI--FPSLAIKLCSPFFIDRIKYSYRIWSLITMSCLGMFLVSFK---------NLFVCLLGISFASISSGFGEVTFLQLTHYY------QISLNGWSSGTGGAGIIGGASYMFLTSIFKVPVKLTLLVFSLLPFAFLFYFKLESNDTNLTYQSLQQIDEAEDDQLVPFPVAFTHTMVPLTTVYLFEYLINQAVAPTLLFPINGDERSKSMPFFF-VTYGTLYQLGVFISRSFGHLMRMRSLYILAFLQGVNLCITVLQSWFYVTHSPWAVMILIFYEGFLGGASYVNTFLNILEQEDPDETEFAMGAVSIADSF-GVFLAALLGLGLEP............................................................................................ 391
33 -13.200[F] KOG1479 Nucleoside transporter  ali follow..  12  21...LGTEGSFVPAFRPQDHHADEQCLMERQQDEVVLVSNEPESGRLFTYLVFYLLGIGTMTPWNFFVTAEDYWKYKFRNASICDLALTATISGTTFLLLNAIFGHHVSLRTKMLGTLWMILILFGVTTGFVEINTDTWQEFLITLIIVVLLNISAATMSGALYGVAGL-FPSE----ITAVVSGQALGGILTAFILVLAFDTGPNTTAFIFFIVGGVLILLCIVCYVILARIRAVPSHNRNGSAEGLPLEPILRQVMSK---ISLALLYTTTLSVYPAVTVLMQSEYGHSVW------MVMFALSNGYFTNILLIMAPKRVKQHEKELASSIMAAALSCGMAVG................................................................................................................................................................... 393
34 -10.900[E] KOG1237 H+/oligopeptide symporter  ali follow..  8  2......................SGSVSRDAEALKSADSSTRRSGGRITFPFMIVTLFGLTLATLGWLQLIVYLIEEYNMKSIAAAKILNIFFTFMFPAIGAIAADSFGTIPVILVSSFISLVGVVLLALTTLFDSPTNIQLGVLYTAITLGCVGAGGLRFTLATAGANQYEKTKQGSFFNWFFFTWYLAASISATAIVYAEENISWSFGFGLCVAANLLGLIVVIFAAIRKRKAVVSTNEKDYHSSVQQVEDFKAVIRIIPLVLAILFLSTPIAMQLGLTVLQGLVMDRR---KIPAGSLQVITLLSTCLFIIVYQKLTGKFPTPIQRVGIGHVFNILSMAVTAIVSVADMSVLWLFPPLVIVGIGEAFHFPGNVALCYQEFPESMRSTATSITSVLIGICFYTSTALIDLIQKTTA---------------PDDINHGRVDNVYWILVIGGVLNLGYFLVCSWFYKYRNLENADHEQDANVSH....................... 557
35 -9.940[P] KOG4505 Na+/H+ antiporter  ali follow..  6  1.......................................................................MAWSQVEISKPHLAYAIIGGFTSLFMLCSLIIKEKLFLGEATMATATGLIFGPYVAKLFVPTSWGNTDYI-TEELARVLLVV---EVFAAGAELPRAYMLRHWRSMFVMLL-----PVMIFGWLVSTGFM--------YALIPRLSFLESLAIAACITATDPVLASSIVGKGKFARRVPGHLRNMLLAES--------GCNDGMAIPFLYLAIYLIIEKPARHAGRDWVCIIILVLGAIIGVIARKMIKFSERRGLMDRESFLVFYFVLALFCGGIGTIIG----LLVSFCAGAAFS-----------WDSWFSKKTEESHVSNVIDLLLNLSFFVYVGAIMPWPQFHMPHMDL---------------SVWRLVVLAICILIARRIPAVL............................................. 346
36 -9.110[S] KOG2766 Predicted membrane protein  ali follow..  10  1MEADSPAGPGAPEPLAEGAAAEFSSLLRRIKGKLFTWNI------LKTIALGQTLSLCICGTAITSQYLAERYKVNTPMLQSFINYCLLFLIYTVMLAFRSGSDNLLVILKRYILLGLADVEANYVIVRAY--------QYTTLTSVQLLDCFGIPVLM-----ALSWFILHARYRVIHFIAVAVCLLGVGT----------------------------------------------------------------------------------------MVGADILAGREDNSGSDVLIGDILVLLGASLYAISNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIDWKIALLFVAFALCMFCLYSFMPLVIKVT--------SATSVNLGILTADLYSLFVGLFL-----------------------------YKFSGLYILSFTVIMVGFILYCSTPTRTAEPAESSVPPVTSIGIDNLGLKLEENLQETHSAVL...... 374
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.