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Query: [P] KOG2662 Magnesium transporters: CorA family, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGEQLDPFSASNLPDFISSQKIGRPVNFEGQTNRGHPFSGLKKRGQSSRSWVKIDQDGNSAVLELDKATIMKRCSLPSRDLRLLDPLFIYPSSILGRERAIVVSLEKIRCIITAEEVILMNARDASVVQYQSELCKRLQSNHNLNVKDDLPFEFKALELVLELSCLSLDAQVNELEMEVYPVLDELATNISTLNLEHVRRLKGRLLTLTQKVQKVCDEIEHLMDDDDDMAEMYLTEKKERAEAHASEELEDNIGEDFESSGIVSKSAPVSPVGSTSGNFGKLQRAFSSIVGSHKSLLSSSSIGENIDQLEMLLEAYFVVVDNTLSKLSSLKEYIDDTEDLINIKLGNVQNQLIQFQLLLTAATFVAAIFAAVTAVFGMNLQDSVFQNPTTFQYVLLITGIGCGFLYFGFVLYFKHKKVFPLLast
1 -117.000[P] KOG2662 Magnesium transporters: CorA family  ali  100  1MGEQLDPFSASNLPDFISSQKIGRPVNFEGQTNRGHPFSGLKKRGQSSRSWVKIDQDGNSAVLELDKATIMKRCSLPSRDLRLLDPLFIYPSSILGRERAIVVSLEKIRCIITAEEVILMNARDASVVQYQSELCKRLQSNHNLNVKDDLPFEFKALELVLELSCLSLDAQVNELEMEVYPVLDELATNISTLNLEHVRRLKGRLLTLTQKVQKVCDEIEHLMDDDDDMAEMYLTEKKERAEAHASEELEDNIGEDFESSGIVSKSAPVSPVGSTSGNFGKLQRAFSSIVGSHKSLLSSSSIGENIDQLEMLLEAYFVVVDNTLSKLSSLKEYIDDTEDLINIKLGNVQNQLIQFQLLLTAATFVAAIFAAVTAVFGMNLQDSVFQNPTTFQYVLLITGIGCGFLYFGFVLYFKHKKVFPL 421
2 -22.600[P] COG0598 Mg2+ and Co2+ transporters  ali follow..  10  39.................................................................ETRLVEERLGIAIDEMQEIELS----DRLYQEDGAEFMTMVPVTFILKGATLVTVRHAEPKP---FQVYANRIMKPNGAACETGELVMLGLLEAMIDRTADALER--------AGNDVDQISREVFRKSNASATKKTRDLQSLIEQIGQKGDLLTVIRESLVSIGRLVAYHVAIEGSTPRKAA----------------------------------------------------------KESRQRIKLVQRDAASLGDHALFLSNKINFLLDATLGLINLEQNQIIKI---FSVAAVVFLPPTLVASIYGMNFEVMPELTWRFGYPYALILMIASALL---PYVYFKRRGWL.. 329
3 -9.240[U] KOG3251 Golgi SNAP receptor complex member  ali follow..  10  3.....................................................................................................................................................................NTLYNHCTKLFQSIQRSLDELERGVQDES-------TISLAGIQGQISASFLSLSRSIDDYDSMVQRELVPAKKKKATIRIQEFRQKHV-QLLEKFDELKAHVRDIAQAKNRKELLGRRGYVNSLDSPYGNSTTDAEIVEGPSDLSRQDGLLKEHDFLGRAESQVDEFLERGRMILG-DLVEQGSVLKATKTKVLNAANTLGITR--------HTLSLINRRSKQDKIIFYCGAFLVFVLFYLIYRWLR....... 235
4 -8.840[O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation  ali follow..  12  1MENQESDEPMQKKPHLLDSVSPNSMARNSSPSHPIAKSVSFFDCDFSLLCLRLVDYE-DATVLQLQNQKLVQQLDLQKKQLYDVESKIQELQLNQTSYDDELISVDDLILLGVRAGA---VPPCAADETFLCRLLQVDSLDTSKSDEVVRKVEHSSTMELMGLFENTIDTQKTKAESISQSLHAVKSTEDATIQLSINDLMKEESKNLREMIDALHVRHKEHSEQIQAYISSHSTDQSELKHLKGQLEEIKAELEENRRKLITLKMQKDAACEGHVTSPAIANGSLSPEKPVDKTKLRE---KDSIDEIKIMAEGRLSELQASQEYNLSLSRQCQDIESLINDRIHHWNAELDRYKILTE............................................................. 402
5 -8.410[U] KOG1666 V-SNARE  ali follow..  9  2...........................................................................................................................................................ASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKL------IRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKS-TSENLSKSRKILRSMSLSIIILLELAILGGLV................................................. 224
6 -7.490[U] KOG0812 SNARE protein SED5/Syntaxin 5  ali follow..  11  125........................................................................................................................................................EIQELTVVIKQEISALNSALVDLQLFRSSQNDEGNNSRDRDKSTHS---ATVVDDLKYRLMDTTKEFKDVLTMRTENMKVHESRRQLFSSNASKESTNPFVRQRPLAAKAAASESVPLPWANGSLQQSQQQQQQQQQQMVPLQDTYMQGRAEALHTVES-LSSIFTQLATMVSQQGEIAIRIDQNMEDTLANVEGAQSQLARMKIFFVLIAFLMIFLFFVA................................................ 377
7 -7.310[U] KOG3208 SNARE protein GS28  ali follow..  10  3................................................................................................................................................................VPSSWDALRKQARKIEAQLDEQMHSYRRLVSTKALSK----DGNESDLEAGIDLLLRQLQQVNAQMQAWVS----------SGGSEMVSHTLTRHQEILQDLTQEFYRHRSSLRAKQEHASLLEDFREFDRTRLDLEDGYGSEQALIKEHMGINRNTAQMDGVISQAQATLGTLVFQRST----FGGINSKLSNVASRLPTVN---------------TILAAIKRKKSMDTIILSLVAAVCTFLIFIYWIT......... 222
8 -7.290[U] KOG3202 SNARE protein TLG1/Syntaxin 6  ali follow..  11  1................................................................................................................................................................MEDPFYEVKADASNQMEQVRKLYNSFMAARNSGVLSPNTELTYAIDELSETLKDLKAAVEIAMKNSEHFGLDEEELKSRRRFVSELDIELNNIQLKMGAAPSTPVSTEPYTVDNGASAGLSEEDHAVNRQYQEQLYQQQDVMLDGVYDTIGNIRGQAALMGEELGQQADLLDTLDNSIETTNSKLRRGMKRLKDF-CITVLIIILIALLVLVIVL.............................................. 225
9 -7.020[U] KOG4112 Signal peptidase subunit  ali follow..  5  1......................................................................................................................................................................................................................................................................................................................................MDGMIAMLPAPLQKLSSHIDFQGQKVAE-----RTYQVILTIAGIIGFLVGF-----WTQQLSYAMFTVLGASAFTALIILPPWPFLFRKNPIV. 84
10 -6.940[U] KOG4809 Rab6 GTPase-interacting protein involved in endosome-to-TGN transport  ali follow..  11  154..............................................................LQTQLKEVLRENDLLRKDVSKLSSSMNSIKTFLKKERAL----EASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQL-------------FQQDSSSRTGEPCVAELTEEN-FQRLHAEHERQA-KELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVHSKFMKNKIGQVKQELSRKDTELL...................................................... 455
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.