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Query: [O] KOG2689 Predicted ubiquitin regulatory protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSEVQTLMDMGFPRERVEYALEVTSNKGVEPAMEWLLAHVDDPIPSRQGAGESPGSTAQPAAAVDSSAAAASSSTSGAGETSAPVAKSLKCDECGKVLRDHTEVEYHAAKTGHTKFSESEEEKKALTEEEKKAQLALIEEKLKQKRIEREEREKIEALQREKNRIKSGKDMTEAKRRMEELEMKKIVEQRKREKDEEKAARDRVKAQIEADKAARKAREQKELGNAEPAPSVSSTTVSSPPAGVKSPPRDYTETRIQVRLQDGSTLQETFNVKEQLSAVRVFIQMKTGIESPFSLMTTFPRKLFAEDDYEKPLEVLGLVPSAVITMTKTPALast
1 -100.000[O] KOG2689 Predicted ubiquitin regulatory protein  ali  100  1MSEVQTLMDMGFPRERVEYALEVTSNKGVEPAMEWLLAHVDDPIPSRQGAGESPGSTAQPAAAVDSSAAAASSSTSGAGETSAPVAKSLKCDECGKVLRDHTEVEYHAAKTGHTKFSESEEEKKALTEEEKKAQLALIEEKLKQKRIEREEREKIEALQREKNRIKSGKDMTEAKRRMEELEMKKIVEQRKREKDEEKAARDRVKAQIEADKAARKAREQKELGNAEPAPSVSSTTVSSPPAGVKSPPRDYTETRIQVRLQDGSTLQETFNVKEQLSAVRVFIQMKTGIESPFSLMTTFPRKLFAEDDYEKPLEVLGLVPSAVITMTKTPA 331
2 -63.600[R] KOG2507 Ubiquitin regulatory protein UBXD2, contains UAS and UBX domains  ali follow..  26  207.........................................................LEGKSGSEAEAASPTALAAEKRAAASKVEGSATTSGAAARNFATNNLIPAVPLMTPAVPVPTQRPLEAQDNTESEERLAEVRNILEQKRKERVEEEKRMEKENELRRRRDGREAQSQQARAKEQELKNMQEQIKRERQEELAARERIRAQIAADRAEQAQRFNTPDISSTTNSVA--ATAASNVITTDASVSSVDETRLQIRLPGGIQRTKSFPAGEVLATVRVYVRNEMLDVRDFTLATSYPRREFQTEDEVKTLNELNLVPNAVVLVLTKEQ 481
3 -44.800[T] KOG1363 Predicted regulator of the ubiquitin pathway (contains UAS and UBX domains)  ali follow..  17  486.....................................................................................................................................................................IFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLEAKE. 650
4 -37.000[Y] KOG2086 Protein tyrosine phosphatase SHP1/Cofactor for p97 ATPase-mediated vesicle membrane fusion  ali follow..  15  1MAALREFVAVGAEEDRARFFLESAG--DLQIALEPSYEDGGDEDIVTISQATPSSVSRGTAPSDNRVTSFRDLIHDQDEDEEEEEGKGAKEHGAVACWKRVTQEPWGETSKPRPYLQGGGYPLGPAPEEDSFLLLAGEKRQHFQQDGSCSMKKSGYSLDNGDLRSYKPSNAQFWSYRRGESTIRRLATVTVNLDMEDHRDEDFVKPKGAFKAFTGEGQKSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAATSFILMTTFPNKELA--DESQTLKEANLLNAVIVQ...... 368
5 -33.800[O] KOG1364 Predicted ubiquitin regulatory protein, contains UAS and UBX domains  ali follow..  15  267......................................................................................................................................................................EGCTLDETSGRKNPLGAKSQKPVEAMSEDEQMHKAIAASLGNGNSTTESQGESSSQQAESHGVADDTVHKIDSAECDAEEPSPGPNVTRIQIRMPNGARFIRRFSLTDPVSKVYAYVKGVAEGADKQPFSLTFQRKSLW-TSLDSTIKEAGIQNTALQF...... 424
6 -11.300[S] KOG2632 Rhomboid family proteins  ali follow..  34  373.EQIQKLVAMGFDRTQVEVALAAA-DDDLTVAVEILMSQQ................................................................................................................................................................................................................................................................................................... 410
7 -11.100[J] KOG0003 Ubiquitin/60s ribosomal protein L40 fusion  ali follow..  18  2..............................................................................................................................................................................................................................................................QIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLI-FAGKQL---EDGRTLSDYNIQKESTLHLV.... 70
8 -10.900[J] KOG0004 Ubiquitin/40S ribosomal protein S27a fusion  ali follow..  18  2..............................................................................................................................................................................................................................................................QIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGPPDQQRLI--FAGKQL---EDGRTLSDYNIQKESTLHLV.... 70
9 -10.100[O] COG5227 Ubiquitin-like protein (sentrin)  ali follow..  8  2...........................................................................................................................................................................................................................SESPSANISDADKSAITPTTGDTSQQDVKPSTEHINLKVVGQDNNEVFFKIKKTTEFSKLMKYCARQGKSMNSLRFL--VDGERIRPDQ---TPAELDMEDGDQIEA..... 104
10 -9.970[R] KOG2295 C2H2 Zn-finger protein  ali follow..  8  275.............DEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIFLR---------NLAPSITRSEIEAVC-NRFSGYLRVAIADPLVERRWRDVNIKEICWGLN.............. 577
11 -9.780[YU] KOG2834 Nuclear pore complex, rNpl4 component (sc Npl4)  ali follow..  14  2..........................................................................................................................................................................................................................................................AESIIIRVQSPDG-VKRITATKRETAATFLKKVAKEFGQNNGFSVYINRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSL 82
12 -9.490[OR] KOG0010 Ubiquitin-like protein  ali follow..  10  2..........................................................................................................................................................................................................................AESGESGGPPGSQDSAAGAEGAGAPAAAASAEPKIMKVTVKTPKEK----AVPENSSVQQFKEEISKR--HTDQLVLI--FAGKILKDQD---TLSQHGIHDGLTVHLV.... 105
13 -9.340[TO] KOG3288 OTU-like cysteine protease  ali follow..  12  2..........................................................................................................................................................................................................................................................TGSFSVKLKSKKGQFIVNDLNEHTTLGELKTKIVQATDEATQLHVLVGYPPKPLSQQQEQRALKAVGINSGETLIVEEKAA 85
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.