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Query: [K] KOG2746 HMG-box transcription factor Capicua and related proteins, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAGESQRRSTQPAERSQDFPGGSVPKLTVTGSNTQITAEAQNKKGSVDGKSMGNDSRKVGKDGILESIGPQIGSLNIFPYASGSHGKFTDWSDFGKDPNTLGGHVQYEYLTEKEIYTREVHLQKASWHVNHSKTQRVRDKEDSGRQPPWLRRGRGGVSPCQEPPARTKYSALRPAFSEASRGVSMFVWRNVEVHSVAVFPWYSIPFLTHPPQPHEAQQPASHSVASNQRKQPAKLAAVAHERPPGGTGSVDPGRPPGAICPESPGPATPHTLRVVEPGKSSPPTMEEEPWAPQESPCWTAQSLSALRKEQDSSSDKDGRNPNKWDKDHIWWPMSGGHDLQQAAPGPGRAHQGHPNQDNQTISQMLSERWYTLGPNEMQKYNLAFQVKVAHLQQGPKEVQLRGQAHKPGASRSVTRARGSGAYQRRALPLPLGCPLNSCQLQPKHSRARIPRSSFCGAEQLHTHMAGEDTASDEEHTVIHEEEGVMMSLLMMALAPPTPISSSRTFGKVYGPTLSSSNTYLDASSSTLAPTSFLLGPGAFKAQESGQGSRAGPLRPLPLGMGAQGCLPRGNPTDMDPTLEDPTTPKCKMRRCSSCSPKPNTPKCAMCDGDSFPFACTGGEAEDRLREPETKKALSSSLHATAALQAHYAHIFPSKVCSAPALTPSPVGVLTAPHLAQTLDAALAAPPLPVPESHAGGQPQRSQDSQYPLRTWTVCGGSNGGQDGYLLPAVPGESWAVSLLRAPVHTMNCGTFRAFHFSENSSYWGYKMECEEGLGPQGGACGLGGVHAPLLSPEGLDSEQNTLIMGDIFHCAKKLPLast
1 -217.000[K] KOG2746 HMG-box transcription factor Capicua and related proteins  ali  100  1MAGESQRRSTQPAERSQDFPGGSVPKLTVTGSNTQITAEAQNKKGSVDGKSMGNDSRKVGKDGILESIGPQIGSLNIFPYASGSHGKFTDWSDFGKDPNTLGGHVQYEYLTEKEIYTREVHLQKASWHVNHSKTQRVRDKEDSGRQPPWLRRGRGGVSPCQEPPARTKYSALRPAFSEASRGVSMFVWRNVEVHSVAVFPWYSIPFLTHPPQPHEAQQPASHSVASNQRKQPAKLAAVAHERPPGGTGSVDPGRPPGAICPESPGPATPHTLRVVEPGKSSPPTMEEEPWAPQESPCWTAQSLSALRKEQDSSSDKDGRNPNKWDKDHIWWPMSGGHDLQQAAPGPGRAHQGHPNQDNQTISQMLSERWYTLGPNEMQKYNLAFQVKVAHLQQGPKEVQLRGQAHKPGASRSVTRARGSGAYQRRALPLPLGCPLNSCQLQPKHSRARIPRSSFCGAEQLHTHMAGEDTASDEEHTVIHEEEGVMMSLLMMALAPPTPISSSRTFGKVYGPTLSSSNTYLDASSSTLAPTSFLLGPGAFKAQESGQGSRAGPLRPLPLGMGAQGCLPRGNPTDMDPTLEDPTTPKCKMRRCSSCSPKPNTPKCAMCDGDSFPFACTGGEAEDRLREPETKKALSSSLHATAALQAHYAHIFPSKVCSAPALTPSPVGVLTAPHLAQTLDAALAAPPLPVPESHAGGQPQRSQDSQYPLRTWTVCGGSNGGQDGYLLPAVPGESWAVSLLRAPVHTMNCGTFRAFHFSENSSYWGYKMECEEGLGPQGGACGLGGVHAPLLSPEGLDSEQNTLIMGDIFHCAKKLP 815
2 -30.000[K] KOG3248 Transcription factor TCF-4  ali follow..  14  1.......................MPQLN--GANDELISEGEQEEKSSENSSAERDLADV-KSSLVNESETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYTSPYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASVSRFPPHMVPPHHTLHTTGIPHPTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAK--VVAECTLKESAAINQILGRRWHALSREEQAKYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSE........................................................................................................................................................................................................................................................................................................................................................................................................ 420
3 -28.800[K] KOG0528 HMG-box transcription factor SOX5  ali follow..  14  82...ENNK-STSPHKRDRE---GT-PKLEEMTRTEQEDSSCMEKLLSKDWKEKGTPESLAEKERQLSTMITQ----EQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHASHPQINQRLKGLSDRFGRNLDTFEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRK--ILQAFPDMHNSNISKILGSRWKSMSNQEKQPYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLR................................................................................................................................................................................................................................................................................................................................................................................................................ 686
4 -24.500[K] KOG0527 HMG-box transcription factor  ali follow..  17  86......................................................................................................................................................................................................................................................................................................................TLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRK--LADQYPHLHNAELSKTLGKLWRLLNESDKRPFEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAE................................................................................................................................................................................................................................................................................................................................................................................................................ 189
5 -13.600[O] KOG3579 Predicted E3 ubiquitin ligase  ali follow..  21  386...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDSSLATSAPLCCTLCDT----HFVQCPSVPSHKFPCQQGASPSGEKCPLVGSNVPWAFMQG---EIATILAGDV---VKK.. 556
6 -11.800[KLB] KOG0526 Nucleosome-binding factor SPN, POB3 subunit  ali follow..  12  480.....................................................................................................................................................................................................................................................................ESFNPGEEEEDVAEEFDSNASASSSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVEVKKGKDPNAPKRPMSAYMLWLNASREK--IKSDHPGISITDLSKKAGEIWKGMSKEKKEEWRKAEDARRDYEKAMKEYEGGRGESSKRDKSKKKKKVKVKMEKKSTPSRGSSSKSSSRQLSESFKSKEFVSSDESSSGENKSKKKRRRSEDSEEEELASTPPSSEDSASGSDE................................................................................................................................................................................................................................................................................................................................... 709
7 -11.800[K] COG5641 GATA Zn-finger-containing transcription factor  ali follow..  16  78...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ANDKSFSTSTAGRMSPDTNSLHHILPKNQVKNNGQTMDANCNNNVSNDANVPVCKNCLT-------STTPLWGAML-CN--------ACGL-GKPRPILKTDVIKSRNR............... 180
8 -9.220[B] KOG4715 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin  ali follow..  9  102...................................................................................................................................................................................................................................................................................RTSATQMPSTPAFAGYNPYCHLAYSNYRLGGNPATNSRVRGSSSITIPKPPKPPDKPLMPYMRYSRKVWDQ--VKASNPDVKLWEIGKIIAGMWQDLADEEKQYLNEYEVEKIEYNESMNAHHNSPVYLAYINAKSLAEAALEE............................................................................................................................................................................................................................................................................................................................................................................................................ 243
9 -8.280[R] KOG4227 WD40 repeat protein  ali follow..  15  676...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NNKDGETSLVTGEADEGRAGTSHKDNPAPSSSKEACLNIAMAQRNQDLPPEGCSKDTFKEETPRTPSNGPGHEHSSHAWAEVPEGTSQDTGNSGSVEHPFETKKLNGKALSSRAEEPPSPPVPKASGSTLNSGSGNCPRTQSDDSEERSLETICANHNNGRLHPRPPHPHNNGQNLGE-HSDDNSSLTGHK-DCEDPTDTPAGHSGL---QRIEL--EDTDSE-NS--------SSKKL. 940
10 -7.790[S] KOG4192 Uncharacterized conserved protein  ali follow..  25  2MKYDSRYRNLDPASRNH----------CLTGTN--ITVRVEHKKG------LGSDGRKLGSDSFLAIMARPAGNMTSMAALLSMASGFP...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 102
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 8 6 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Liu T, Rojas A, Ye Y, Godzik A. Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family. Protein Sci. 2003 Sep;12(9):1872-81.