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Query: [G] KOG2762 Mannosyltransferase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEGEQSPQGEKSLQRKQFVRPPLDLWQDLKDGVRYVIFDCRANLIVMPLLILFESMLCKIIIKKVAYTEIDYKAYMEQIEMIQLDGMLDYSQVSGGTGPLVYPAGHVLIYKMMYWLTEGMDHVERGQVFFRYLYLLTLALQMACYYLLHLPPWCVVLACLSKRLHSIYVLRLFNDCFTTLFMVVTVLGAIVASRCHQRPKLKKSLALVISATYSMAVSIKMNALLYFPAMMISLFILNDANVILTLLDLVAMIAWQVAVAVPFLRSFPQQYLHCAFNFGRKFMYQWSINWQMMDEEAFNDKRFHLALLISHLIALTTLFVTRYPRILPDLWSSLCHPLRKNAVLNANPAKTIPFVLIASNFIGVLFSRSLHYQFLSWYHWTLPILIFWSGMPFFVGPIWYVLHEWCWNSYPPNSQASTLLLALNTVLLLLLALTQLSGSVALAKSHLRTTSSMEKKLNLast
1 -137.000[G] KOG2762 Mannosyltransferase  ali  100  1MEGEQSPQGEKSLQRKQFVRPPLDLWQDLKDGVRYVIFDCRANLIVMPLLILFESMLCKIIIKKVAYTEIDYKAYMEQIEMIQLDGMLDYSQVSGGTGPLVYPAGHVLIYKMMYWLTEGMDHVERGQVFFRYLYLLTLALQMACYYLLHLPPWCVVLACLSKRLHSIYVLRLFNDCFTTLFMVVTVLGAIVASRCHQRPKLKKSLALVISATYSMAVSIKMNALLYFPAMMISLFILNDANVILTLLDLVAMIAWQVAVAVPFLRSFPQQYLHCAFNFGRKFMYQWSINWQMMDEEAFNDKRFHLALLISHLIALTTLFVTRYPRILPDLWSSLCHPLRKNAVLNANPAKTIPFVLIASNFIGVLFSRSLHYQFLSWYHWTLPILIFWSGMPFFVGPIWYVLHEWCWNSYPPNSQASTLLLALNTVLLLLLALTQLSGSVALAKSHLRTTSSMEKKLN 458
2 -16.600[S] COG5650 Predicted integral membrane protein  ali follow..  10  41......................................TQRFWTPLRVLITTSLVFLAMGFLTKANYNDIVPLYGGRGID----APGFPYAQEGDLTRYMEYPVLGGIFQWICGIITRFLYPVVDVIPFHLALAFFWVLVIRMMVELTGNRVWDTVLVAASPLVAVHAFTNW--DTPAIAAVIGAMLAVK------------RGNPLVAGVLIGAGTAFKLWPLYLLG--AYLVLAVKNKNLKPFITMAAAAAVTWLVVNVPVMIAYPKAWNE-RLNRERGAEWTYQVIDRNLPINLNDPVLLNVLSFGLFGASCVAILILGLKVQ---------------------RTPRVAELAFLIVAAFLLFNKVWSPQYSLWLVPLAVLAFPQWKVLFPWMVTDAMVWPILMWHMLGTDNKGLPHEMLDLIVIS............................. 435
3 -12.400[G] KOG3893 Mannosyltransferase  ali follow..  13  437................................................LLLLLGLLMRLVLL-ALKFTDIDYFVFSDASKYVS-IGMSPYMRDTYRYTPML-----AILLLPTQYGFP-----SWGKYLFSISDLIAGWLMIKLLSRRIS----------YKRSLIYSSFWILNPFVAIISTRGNCEAILGILSIALLYLIEKKSVWLASLILGFSVHFKIYPFMYGIAFLVYFSKPKKGSSINQLKIVVGSLFMFTICNLLMYYLYGSPFLEHTYLYRTDHRHNFSLHHLNLYYESSFGAKASSLFAFLPQLSLCMLIPLVFGK------------------------KNLPGTLFAQTFAFVTFNKVCTSQYFMWYLVFLPLVLPNSKLLSLICLSLWIIGQLLWSVFIPLWLSGLLFFFFNVYELKIILDS........................ 814
4 -12.300[GE] KOG2575 Glucosyltransferase - Alg6p  ali follow..  13  43................................................LCISLFALLIRSAVTMYPYSEAHWMEYRNGTYNDLTYWGLDYP-------PLT--AYQSYIHGIFLRFFNPEESYLGKLLMRWTVLSSDAFIFFPAALFFVLVYHRNRTRGGKSEVAWHIAMILLNPCLILI-GHFQYNCISLGLTVGAIAAVLCESEVLTCVLFSLALSHKQMSAYFAPAFFSHLLLRRKSPILSVIKLGIAVIVTFVIFWWPYVLDDFLMVLSRLAPFERGIYEDYVANWCTTSKNLFTTQSLKSISLAATILASLPSMVQQILSP---------------------SNEGFLYGLLNSSMAFYLFSFQVHEK--SILMPFLSATLLALKLPDHFSHLTYYAL---FSMFPLLCRDKLLIPYLTLSFLFTVIY......................... 437
5 -12.300[O] COG4346 Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase  ali follow..  9  170....................................................................................................EHPFLGKDIIALGMLIEDKPFYWRIPGIIEHALIVIIVTLVAYKITKSYLASSIAATFAALDPLLFATGIVAMLDIHVAFFIALFMLFLA------------LDRIRLSGIALGLAAATKLSGAFAFPILWFKILKEKDLKEYLISGLVLPMVSFLIPEITIIKAIGFIPWLEEFIASFSWHLWMWFVSLKHFDPDVYAVTDPILMISMIVFVFAVPYVSLR--------------------RKGLSEIFWMFWSIIAFFALQYILGGKTQFIFY--ATPLIPPGA........................................................................ 437
6 -10.100[M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family  ali follow..  14  9................................................GLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGEKPIAGY-----WINSIGQWL---GANNFGVRAGVIFATLLTAALVTWFTLRLKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWL-AMQAQTWKGKSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLQREPNFWHYFFHIQRFWYYVPVIIAGSLPWLGLLKHSATVYLLSWTIMPLLFFSVAK--------------------------GKLPTYILSCFASLAMLMAHYA........................................................................................ 331
7 -10.100[K] KOG2576 Glucosyltransferase - Alg8p  ali follow..  13  39............................................................ITHSLPISE--W--YKSSISEWTL----DYECVLSWIAYFFGFDKAMLDPYNLNYVSPSTVVFQRGSVIVLELVLLFALREYVLSSNVKDQRNALLTAIDIFLSPGLLII--YNGFLFGLLLWSIVLAK------------PEKNMLLSAAIFSALICFKHIFLYVAPAYFVYLL-NFRPQFLNILKLGSTVISIFLLAFGPWIYMKQIQLLSRLFPFSRLCHAYWAPNWALYSFVDRVAFAVLPRFGYALNQGTSINAPTR-PPALTFYICLGLQITVLIKLFIKPTWRVFVGAVTLCGWISFLFGWHVHEK--AILMVILPFSILSLIDRRYLEAFRPLAVSGYLSLLPLLFTLNEAPIKYLFTGAWIAML......................... 422
8 -9.960[G] KOG4123 Putative alpha 1,2 mannosyltransferase  ali follow..  10  20................................................YFCFAAVRLLLVFVPQLGYVHPD--EFFQSVEHFRLEHTRTWEPVRSIVLPFALLRIPWSFYEFVAECLK----VVFPRLIYTLISFSNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYTLGELHMMHLSIDNFVFTWNFIKANLDSAQT-NMPMLFNVLALASLGAFAQ-----------LLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLI........................................................................ 415
9 -9.930[R] KOG2647 Predicted Dolichyl-phosphate-mannose-protein mannosyltransferase  ali follow..  11  1............................MAKALESNSKSRKETILIKYAIFSRLLVLFLTILWRSLLQPYDWDSYFLRITECGYEYEQTYA-------PL-LPFFISLLSRTVFAPLVP-SGFTVSNLAFIFAAIYLFRVSVIILKDTEASFRASIIFCFN----SIFYSSIYSESLYALFSIGGVYHL------------LSGTSNVGVLWFALSGCARSNGILNAGYICFQTMHYQKRRAYLAMQVFIAGFLRCICICLPFVAFQAYGYYNICHGIQKILVSDRGVGF-----KYFQFKQLPNFLLASPILSLAVCSIMSYMKSRPELFISLVTGTKVAPEKSGYLSADVFPFIVHLSFMVTTAFFIMHVQVATRFLSASPPLYWFASWSYCAAYILLGTLLFS-NFYPFT............................................. 492
10 -9.930[S] COG5617 Predicted integral membrane protein  ali follow..  8  2.......................................KRKLYYLTLATISVIEYIPLYLAPSPPALQINGNGHLFKVHKLMTSGWKPWIEDWYAGYPFFYPPLSYLTAGVLGKVL--GSDTKGYAATLMLTSFLGALALHHYLKSTGREPCILIFLLFPWHLTVSYIEGNFPRANAIHLAPLFLLSLYW-------LREKRERYLIASALGISIVALTHYSILPLLIITGILILWDDLRTMTALGNGIKVLGAVIGLTSFWYV--PFLFDKKWVEFWNISENKALFKSFSLNPTLLKSPFGILLILLLLIFAIFAIKNLVDRK------------------------------KVILAGLYLYLSLGFYSPTTWLYSFPLLSIVPPYRWFDLEALIIPLLIGESLKRVQRKSMVALVIIPFTVLAFMNVPKINPYPQDLIKICENIKEEPGDDWR. 382
11 -9.570[O] COG4745 Predicted membrane-bound mannosyltransferase  ali follow..  12  10........................................PRVAAAVVAVTAAALLARLWALGWRVAH--DEARVADWTLQYMDLGAWQYRPI---HGPFLP-----HVNGVVFDVF--GATDFTMRLVVAVVGGLLPLTAWLYRTRLSDVEVGALAVLLAANPVVLYYSRFMNDLLLAGFMFTAVGLFV-----RFLDTHRARYLYASAVPFALAFTTKENSLLYPLCWLGALALV............................................................................................................................................................................................................................. 192
12 -9.200[MU] KOG2516 Protein involved in dolichol pathway for N-glycosylation (mannosyltransferase family)  ali follow..  9  8.................................................TVLLTVISFHLIQ--APFTKVEESFNIQAIHDILTYSVFDISQYDHLKFPGVVPRTFVIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLDIYIYDSAGTWFLLFLIGSFHL--FYSTRTLPNFVMTLPLTNVALGWVLLGRYNAAI----------FLSALVAIVFRLEVSALSAGIALFSVIFKKISLFDAIKFGIFGLGLGSAIS---ITVDSYFWQEWCLPEVDGFLFN-ASKWGVEPVTAYFTHYLRMMFMPPTVLLLNYFGYKL--------------------------APAKLKIVSLASLFHIIVLSFQPHKEWRFIIYAVPSIMLLGAT................................................................... 346
13 -9.180[R] KOG2552 Major facilitator superfamily permease - Cdc91p  ali follow..  8  21................................................IWTLASTIFRLFLIFEVSTPHTSLRR-LAEGYWLKQSSLSPYAGSMYHGSPLL-----LSILGPLTVQSDK-VAGSKGNRVIICADLLSALLLRAIGQKLQKSYRMNLRPLGVLRSSQAALVYLWNPFTILSCVGLSTSPIENLAVIVSLYGAVTRRVPLAAFGLIMATHLSLYSAPLVFPLIFLLFSWRTVLHFVFWVLVWSSYVLVLCSLSLKQYGGLEEMFKRTYGF-EDLSPNIGVFWYFFAEAFEFSRNYLLIIFNLYILLTSIPSLMFRLK------------------------HRPCFLAFAYLAFTSILKSYPSVGDAALYLSLWALFVFFIFCGYIGFSLLSPVMHNFWNFY----GNAMGYACFQFMFVEKSVNAMLNHDQALKKATAEMTKN...... 474
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;