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Query: [DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRSMFEVYDMPPHSDFYCKISMKGCLAVFRNMNEVEYCELNLLDNQTNLQVNLRCKLETTKEATISIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANSGSVVAKNYIEGARVNDKFMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLFAECLNASLTLEFDEAGMPFLLKIKKHGEIECLLIMSTLSPDDISFSEDYCQKDLTVQDEDVRAAAAKRKSSVSKPNVTNKRKGSSSEPAAVQPKRRVEETQLESSLDNPLFQFRDSEAPSVQHPRILAEVDTVVLIEDEAEQEALMLAAADAALEASMAPAPEPPNSTEVCFINTDDSQQPKPAKSSSDEDETIPQSPERPNKVLGVLLGLLQGCVSRLKTMLRLDEHLISGYELLLast
1 -102.000[DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component  ali  100  1MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRSMFEVYDMPPHSDFYCKISMKGCLAVFRNMNEVEYCELNLLDNQTNLQVNLRCKLETTKEATISIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANSGSVVAKNYIEGARVNDKFMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLFAECLNASLTLEFDEAGMPFLLKIKKHGEIECLLIMSTLSPDDISFSEDYCQKDLTVQDEDVRAAAAKRKSSVSKPNVTNKRKGSSSEPAAVQPKRRVEETQLESSLDNPLFQFRDSEAPSVQHPRILAEVDTVVLIEDEAEQEALMLAAADAALEASMAPAPEPPNSTEVCFINTDDSQQPKPAKSSSDEDETIPQSPERPNKVLGVLLGLLQGCVSRLKTMLRLDEHLISGYELL 456
2 -50.100[L] KOG1636 DNA polymerase delta processivity factor (proliferating cell nuclear antigen)  ali follow..  9  2LELRLV--QGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEGFEHYRCDRN--LSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFEPTQDKIADFEMKLMDIDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANIVLRQNTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATP-LSDTVTISLSS-ELPVVVEYKVAEMGYIRYYLAPKIEEEEDTNP............................................................................................................................................................................................. 263
3 -28.700[DL] KOG3194 Checkpoint 9-1-1 complex, RAD1 component  ali follow..  11  2..FQAETVCLKQIQSTLRCID-FSKECTIEITSRGLRFAVEE-SQSLQAHAFLDKSLFQTFNFQGDDTYMFQTMISPLLQSLSIYTDGKECKVQYNGPGCPFIWEVEEMAGYATACELTMECEDDVDINRLASTLCTKIIMKSNWLYDALVELDNNMGEIHTSSQKSTFLLRCVGALST-----TEIEYPNEKSVLESFETDSENTYSYRFSLIRHALK-ALQVGSKVNLRIDENG-TLSIQIQEGLCTFVDFCIVPLDLVSEDEEEDEEEEPAESNQSDNNVLRNDPNYRGDAETEDEDS........................................................................................................................................................... 323
4 -27.400[DL] KOG3999 Checkpoint 9-1-1 complex, HUS1 component  ali follow..  11  1MRFKTRISNLYTLTRLVQALDKIGRFCWLRLMPETVNFVIVPDFRMTQVWSVLEVEIFEDYVVQSDNVINLEVPIDNFYKALRSAANASDSTVRLSKKNNQPLLSLSTTWSGRAFGSLSQSYVSVIKEPTAPEPDCHIFLPQLNFLRHVVDKYKSLSDRIIMSANMPSARVSTKWKGLENPELDPSQVEDISRHPSQTRAPEEFVHMRLDSKDLVNMLK-ISSVAKRVIACFCE-GHALVLYVEDEHTAVLTYYISTYVD.................................................................................................................................................................................................... 287
5 -10.800[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)  ali follow..  10  126.RFSLPAEQLKMLQRTSFAVSRVLTGVLLAIANGVATIVGTDGKRLAKIDAEVTL--------DKSFSGEYIIPIKAVEEIIKMCSDEGEAAIFL--DQDKIAVECDNTLLITKLLSGEFPDFSPV-----STESNVKLDLHREELITLLKQVALFTNEVKFSFLPGELTLTANCTKVGEGKVSMAVNYS-----------GELLEIAFNPFFFLDILKHSK--DELVSLGISDSYNPGIITDSAS.................................................................................................................................................................................................................. 353
6 -6.970[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  8  758...............................................................................................................................................................................................................................................................VAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPP..... 953
7 -5.490[R] KOG2295 C2H2 Zn-finger protein  ali follow..  10  345..................................................................................................................................................................................................................................................................LAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIFLRNLAPSITRSEIEANRFSGYLRV 544
8 -5.410[S] COG1756 Uncharacterized conserved protein  ali follow..  6  7LHLIIADAELETVPEQILDHPAIVNYAKRRKRKPEKIILDSTYHHAALKQLE-----------DGERRGRPDIVHICLLNALDSLNKEDRLRVYVHTRNDYV-IYIKPETRLPRNYNRFIGLMESLFEKGAVPEDLELLRLERKTLQELINEINPDA--FVMHEEGELMIPKNFGKLLDKFKKPAVIIGGFPHGDFRSRVEGVKISLYEPLMAWTIVNEVIVSYEWEVIKKFST.............................................................................................................................................................................................................................. 229
9 -5.050[Z] KOG4462 WASP-interacting protein VRP1/WIP, contains WH2 domain  ali follow..  6  123...............................................................................................................................................................................................................................................................APPSAPAPPTPQSELRPPTSAPPRPSIPPPSPASAPPIPSKAPPIPSSLPPPAQPAAPVKSPPSAPSLPSAVPPMPPKVPPPPLSQAPVANTSSRPSSFAPPAGHAPNVTSESPKFPNRGPSIPSASVPPVPPSSYVLQQRPNRVDDHGRFHFKDDSYLPIPHPFLG---------------VPKVYRGGSGTTVP..... 303
10 -5.000[S] COG4848 Uncharacterized protein conserved in bacteria  ali follow..  9  1MKMTSR----KLSDILKQRLQHENRSFLFDREKDTLRVEDQTTKKGITLDL---PPIIAKWELKKDEAID-----EIVYYVSEAMTAMEGKAQEMTGKETRIYPVIRSTSFPDKSSEYYALDLGKTYRLIDQRMLEKENWTKERIRETAAFNLRSLPTVVKEDTVAGNYFYFFRANDGYDASRILNEAILNEYKQ----HAEGELAISVPHQDVLILASGYDILGQMSMSFFAGGTVPI......................................................................................................................................................................................................................... 243
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 7 2 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.