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Query: [S] KOG2827 Uncharacterized conserved protein, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSATKHNERVGRRNDRKRDASQACLPERSPSLRSEPRQQRSHPYLQTRTNTHRQRPMIRPSSVVSMSGRSIAPSDSSENDDRHFDVDEEMESMSLDSPLPIEVPARPFPDKPYYWMNDYKTLEFIRTNFPSDSFYVMHNGKIIENFNAFIDENMGQSLVKYSFHLRVRGGKGGFGSLLRSFRVNKSTNKLMMRDLNGRRMASVDEEAKLKRYLEKQARKEQELKEKRKAKLEKLTAGPAKHMFEDQDYLSRREEIINKTEDACEAGFALMLEMKRNSRKSKEQENKNDEDEDDDVNAEDVTDLFNDRGGRKRKIAAPSIGEDGGNKRINDESDDSEDDSENEVDPEELEAIRQYFEAKKQDEKDNGEGTSEAVPEVLVDEQEIEPAKRPRLDSASNIDDLPKIDVKTPCEYGPISLDDFTSAEDLELLGLEHLKSALNDRGLKCGGSLVERAARLWCVKGKQPREYPKNILTPELKKKIAEEEEAERKAAKKAKKSKKNQLast
1 -178.000[S] KOG2827 Uncharacterized conserved protein  ali  100  1MSATKHNERVGRRNDRKRDASQACLPERSPSLRSEPRQQRSHPYLQTRTNTHRQRPMIRPSSVVSMSGRSIAPSDSSENDDRHFDVDEEMESMSLDSPLPIEVPARPFPDKPYYWMNDYKTLEFIRTNFPSDSFYVMHNGKIIENFNAFIDENMGQSLVKYSFHLRVRGGKGGFGSLLRSFRVNKSTNKLMMRDLNGRRMASVDEEAKLKRYLEKQARKEQELKEKRKAKLEKLTAGPAKHMFEDQDYLSRREEIINKTEDACEAGFALMLEMKRNSRKSKEQENKNDEDEDDDVNAEDVTDLFNDRGGRKRKIAAPSIGEDGGNKRINDESDDSEDDSENEVDPEELEAIRQYFEAKKQDEKDNGEGTSEAVPEVLVDEQEIEPAKRPRLDSASNIDDLPKIDVKTPCEYGPISLDDFTSAEDLELLGLEHLKSALNDRGLKCGGSLVERAARLWCVKGKQPREYPKNILTPELKKKIAEEEEAERKAAKKAKKSKKNQ 500
2 -17.700[O] COG5272 Ubiquitin  ali follow..  18  1.............................................................................................MQIFVKTLTGKTITLEVEPSDSIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES-TLHLVLRLRGG.......................................................................................................................................................................................................................................................................................................................................... 76
3 -17.500[DO] KOG0005 Ubiquitin-like protein  ali follow..  14  1.............................................................................................MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGS-VLHLVLALRGG.......................................................................................................................................................................................................................................................................................................................................... 76
4 -17.300[J] KOG0003 Ubiquitin/60s ribosomal protein L40 fusion  ali follow..  17  1.............................................................................................MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES-TLHLVLRLRGG---IEPSLKALASKYNCDKSVCRKCYARRKNQLRPKKKLK.................................................................................................................................................................................................................................................................................................. 128
5 -17.300[OR] KOG0001 Ubiquitin and ubiquitin-like proteins  ali follow..  11  26.VKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHIQDKEGIPPDQQRLIFAGKQLEDGRTL--ADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLMQIFVKTLTGK------TITLEVESSDTIDNVKAKDQQRLKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDK.............................................................................................................................................................................................................................................. 337
6 -15.900[J] KOG0004 Ubiquitin/40S ribosomal protein S27a fusion  ali follow..  18  1.............................................................................................MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES-TLHLVLRLRGG.......................................................................................................................................................................................................................................................................................................................................... 76
7 -14.500[L] KOG0011 Nucleotide excision repair factor NEF2, RAD23 component  ali follow..  7  3.............................................................................................VTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGFPVAGQKLIYAGKILSDDVPIRDYRIDEKNFVVVMVTKTKAGQ----GTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQFQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQMNYIQVTPQEK------EAIERLKALGFPE-SLVIQAY-FACEKNENLAANFLLS........................................... 357
8 -12.700[OR] KOG0010 Ubiquitin-like protein  ali follow..  9  1.........................................................MAESGESGGPPGSQDSAAGAEGAGAPAAAASAEPKIMKVTVKTPKEK-EEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGI-HDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTSST----NPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSASSGTASTVGGTTGSTASGTSGQSTTGLGALGSTGGSSGTNGSNATPSENTSPTAGTTEPGHQQFIQQMLQALAGVNPQLQNPEVRFQQQLEQLSAMGFLNREANLQAL-IATGGDINAAIERLLG........................................... 585
9 -11.400[O] KOG3493 Ubiquitin-like protein  ali follow..  10  1............................................................................................MIEITCNDRLGKKVRVKCNPDDTIGDLKKLIAAQTGTKHEKIVLKKWYTIFKDPIRLSDYEI-HDGMNLELYYQ.............................................................................................................................................................................................................................................................................................................................................. 73
10 -11.100[R] KOG2295 C2H2 Zn-finger protein  ali follow..  10  299...........................................................................................................................................................................................................KTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSI--LRNLAPSITRSEIEAVCNRFSGAIADLVERRWYRRG........................................ 559
11 -11.000[A] KOG2242 Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain  ali follow..  11  1..................................................................................................................................................................................................MDVRRLKVNELREELQRRGLDTRGLKTELAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAY--ASYGVRRGRVCFE.................................................. 260
12 -10.200[D] KOG4259 Putative nucleic acid-binding protein Hcc-1/proliferation associated cytokine-inducible protein, contains SAP domain  ali follow..  31  2....................................................................................................................................................................................................................................................................................................................................................................................................................................PESDVTKMKVADLKRELKLRGLAVNGNKTELQDRL............................................. 36
13 -10.200[K] KOG2478 Putative RNA polymerase II regulator  ali follow..  11  331.................................................................................................................................................................................................RLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD.......................................................................................................... 531
14 -9.940[K] KOG4495 RNA polymerase II transcription elongation factor Elongin/SIII, subunit elongin B  ali follow..  6  1.............................................................................................MDVFLVIRRHKTIFTDAKESSTVFELKRVVEGILKRPPDEQRLYKDYQLLDDGKTLGECGFTSQTATVGLAFRAHDA.......................................................................................................................................................................................................................................................................................................................................... 84
15 -9.700[R] KOG4264 Nucleo-cytoplasmic protein MLN51  ali follow..  11  1.......................................................................................................................................................................................................MADRRRQR-------ASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPA-DLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAP-----KSRQELIAL----G----------YDIRS---AHNPDDIKPRRIRKPRYGSPPQRDP............ 271
16 -9.500[K] KOG3766 Polycomb group protein SCM/L(3)MBT (tumor-supressor in Drosophila and humans)  ali follow..  8  588..............................................................................................................................................................................VEDPHWNFQEETLKAKYRGKTYRAVVKIVRTSDQVANFCRRVCAKLECCPNLFSPVLISENCPENCSIHTKTKYTYYYGKRKKISKPPIGESNPDSGHPKPARRRKRRKSIFVQKKRRSSAVDFTAGSGEESEEEDADAMDDDTASEETGSELRDDQTDTSSAEVPSARPRRAVTLRSGSEPVRRPPPERTRRGRGAPAASSAEEGEKCPPTKPEGTEDTKQEEEERLVLESNPLEWTVTDVVRFIKLQDIDGQALLLLTLPQECMELKLGPAI-----KLCHQ----IERVKVAFYAQ........................... 891
17 -9.320[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  6  490.....................................................................................................................................................................................KQSKVAHDERCKILIS-SLQDTLHGIEAKSYNRRERSRSRERSHRSRQRRER-----STSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPAPPSSQQ........................................................................................................... 695
18 -9.170[J] KOG0650 WD40 repeat nucleolar protein Bop1, involved in ribosome biogenesis  ali follow..  8  3...........................................................................................................................................................................................................................................................................KKLALKRRGKDSEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEEDNEEEESTDGEEVEDEEKDSKSKQTDDKPSGSGAASKKALTAELPKRDSSKPEYQDSDTSDEEDIRNTVGNIPMHDEYKHIGYDWDA------KKI--IKPPQGDQIDEFLRKIEDPDLTGQDVRLTDEDIALIKRIVSGR 237
19 -9.100[S] KOG4610 Uncharacterized conserved protein  ali follow..  7  297.........................................................................................................................................................................................TCKNSLVIILQLYRLYVVNAEFWKNRRESRMAKSRQFQSRRKVQDADQNSIYMISNERGGDVKKKIKRAKDKDYAEQEAVYSKKKKDKKDKKKRKRKDTGYSTASSQNLYSTKASGTDKDTRRKDKKGKKSKRTCSSSPSDCDLAKKQKRKNADKNDKKKSRKIEAVVEESSSSSSSSSDSSNSTLPSYEVIDEKKARRRKHRGSSSDTSSGDSSSSSSSSSSSDSS........................................................................................ 523
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;