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Query: [Z] KOG3121 Dynactin, subunit p25, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEIPDTYYSKDEYVETASGNKVSRHTVLCGSQNIILNGKVIVQSGAIIRGDLANVRTGRYCVIGKNSVIRPPYKQFSKGIAFFPMHVGEHVFVGEGAVVSAATIGSYVYIGKNAIIGRRCVLKDCCVIEDGAVLPPETTVSSYMRYTARGTIEGGQGNPYFVPAAMQDEMINYTKSFYEHFVRAPAPASLast
1 -86.200[Z] KOG3121 Dynactin, subunit p25  ali  100  1MEIPDTYYSKDEYVETASGNKVSRHTVLCGSQNIILNGKVIVQSGAIIRGDLANVRTGRYCVIGKNSVIRPPYKQFSKGIAFFPMHVGEHVFVGEGAVVSAATIGSYVYIGKNAIIGRRCVLKDCCVIEDGAVLPPETTVSSYMRYTARGTIEGGQGNPYFVPAAMQDEMINYTKSFYEHFVRAPAPAS 189
2 -61.800[R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily  ali follow..  13  2....SYYAFEGLIPVVHPDAFVHPSAVLIG--DVIVGAGVYIGPLASLRGDYGRLILEAGSNLQDGCIMHGY--------CDTDTIVHENGHIGHGAILHGCVVGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFQGEARQLLVGSPA---------RVLRQVTDQELHWKHLNTKEYQDLAIRCR 167
3 -25.500[E] COG2171 Tetrahydrodipicolinate N-succinyltransferase  ali follow..  11  99...............QKEGFRVVPPAAV--RQGAFIARNTVLMPSYVNIG----AYVDEGTMVDTWATV------------GSCAQIGKNVHLSGGVGIGGTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQS--TRIYDRETGDIHYGRVPAGSVVVSGNLPSK.................... 241
4 -25.000[R] COG0110 Acetyltransferase (isoleucine patch superfamily)  ali follow..  17  58.................TEAYIEPTFRCDYGYNIFLGNNFFANFDCVM--DVCPIRIGDNCMLAPGVHIYTATHPIDPVARNSGAELGKPVTIG-----------NNVWIGGRAVINPGVTIGDNVVVASGAVVTKD--VPDNVVVGGNPARIIKK................................. 182
5 -22.600[M] COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase  ali follow..  14  33..........GPQVEIGEGTVLKSHVVVNG--QTKIGRDNEIYQFASIAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKAHDCTVGNRCILANNATLAGVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQD--VPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNAYKLLYRSGKTLD 230
6 -20.500[J] KOG1461 Translation initiation factor 2B, epsilon subunit (eIF-2Bepsilon/GCD6)  ali follow..  23  313...............KASDATQLPSAHV--GASYVIGHATNIGSGTKILNSV----IGNGCSIGSNVVIQ-------------GSYIWNNVTVEDGCEIRNAIVCDEVKVCAGAIVKPGVVLSFKVVVGRDFVVPAYSQV................................................. 418
7 -17.500[J] KOG1462 Translation initiation factor 2B, gamma subunit (eIF-2Bgamma/GCD1)  ali follow..  20  354...............RLVDVTVSERALV--GADCMVNEGTTIKDNSNIKKSI----IGKNCVIGKGVVVS-------------NSILMDNIVVEDGVRLESCIVASGAQIGAKSKL-RECEIGVDHRVEAGRIARGERLVDMEKI............................................ 463
8 -16.700[E] COG1045 Serine acetyltransferase  ali follow..  16  141................................QVDIHPAAKIGRGIMLDHATG-IVVGETAVIENDVSIL------------------QSVTLGGTGKSGG-KIREGVMIGAGAKILGNIEVGRGAKIGAGSVVLQP--VPPHTTAAGVPARIVGKPDSDKPSMDMDQ..................... 258
9 -15.900[E] KOG4750 Serine O-acetyltransferase  ali follow..  17  180................................AVDIHPGAKIGKGILLDHATG-VVIGETAVVGDNVSIL------------------HGVTLGGTGKQSG-KIGDGVLIGAGSCILGNITIGEGAKIGSGSVVVKD--VPARTTAVGNPARLIGGKENPRKHDKIPCLTMDQT............... 303
10 -15.300[MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)  ali follow..  15  252...............IGQNTYIDPSAHIEA--PAVIGNNCRIGARVQIEA---GTVIGDNVTIGADANLKRP-------------IVWNGAIIGEEAQLSACVISRGTRVDRRAHVLEASVVGSLSTVGEEAQISPGVRVWPSKKI........................................... 364
11 -15.200[M] COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase  ali follow..  19  143..........GKQARLGDNTKLWANVTIY--HKVEIGSDCLIQSGTVIGADLGSVRIGDRVEIGACTTIDDDTVIEDNVIIDNQLQIAHNVHIGYGSALAGGTIAGSTRIGKYCIIGGASVINGHIEIADGVTITGMGMVEKGMYSSGIPLQTNKEWRKTAARVHRIDDMHKRLKALEKLLEQSDTV.. 343
12 -14.200[GMO] KOG1460 GDP-mannose pyrophosphorylase  ali follow..  15  275.....LSQFRLTSPQLLASGDGTRSAIVIG--DVYIHPSAKVHPTAKIGPN---VSISANARVGPGVRLMSC-------------IILDDVEIMENAVVTNAIVGWKSSIGRWSRVQAVTILGDSVAVEDEVVVTSSIVLPNKTLNVSVQDEII................................... 414
13 -13.600[M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)  ali follow..  15  301..............KIGANSKIAPFSHL---EGCEVGENNQIGPYARLRPQADDVHVGNFVEIKNAAI---KGTKANHLTYIGDAEVGSKTNFGAGTIIHKTVIGDEVRIGSNCVLVSPVKIGNKVTTGAGSTITRN--VEDGKLALARSRQTIIDG................................ 447
14 -13.100[R] COG4801 Predicted acyltransferase  ali follow..  17  1...............MLKHLLVPDNTRI-DTSRIVVEGDVIVGNHSSIQYSIDMVIMGEGVAVSGDVVACSDTRIDMWSKMGSNVEVGKNAYLGEFVSIEGLTVEGDLDVGKEVKIKGGFVAKGWIVVRNPVPVIMFLFL................................................. 127
15 -11.900[M] KOG1322 GDP-mannose pyrophosphorylase/mannose-1-phosphate guanylyltransferase  ali follow..  12  363TEQPPKFQFYDQKTPFFTSPRFLPPTKVDKCRIL---DSIVSHGCFLRECSVQHSIVGIRSRLESGVELQDTADFYQTEAEIASLLAEGKVPVGQNTKIKNCIIDKNAKIGKNVVIANADGVEEGDRPEEGFHIRSGITVVLKNATIRDGLHI.................................... 518
16 -10.900[G] COG0448 ADP-glucose pyrophosphorylase  ali follow..  13  303........YDQSWPIRGNPVQTYPSKFFYKKENARPVDNSLISGGCVITASISYSVLFDRIKINEGSQIDHC-------------VVLPQVTIGKNCKLKRCIIDRHSVIPDGMEIGVDLELDQRFRVSSGGVVLNGEEVASEAHL........................................... 438
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;