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Query: [E] KOG3145 Cystine transporter Cystinosin, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSFPVAFLLVLFLVPFTFATNNLVVRQKELEIVIGGEVSVNFQIKNHTSQSLNATRISLSQSPYISHPDAILVDNWNANVTVLGSQLVSGAILEALNCTTDGSITCPLDLEDAFARITVIRSHFLAILIQIVGWTYFFAWSISFYPQMYLNFKRKSVVGLNFDFLSLNLVGFCAYAIFNLLMYYNSHVKNEYNIVNPRSPPPVLLNDVVFAVHAFLACFITILQCLFYERDNQSVSSKCIALMIVLISFGFCSAAATVLRKIQLLSFVTSLSYIKMAVTCCKYFPQAYFNYTRKSTVGWSIGNIMLDFTGGTLDILQMILQAVNVNDWSAFYANPVKFGLGFVSIFFDIIFMVQHYVLYPNAEVPHNEYHGVDNPNPDNIARDAEQYAGDSESMESTEPIIVHDLast
1 -125.000[E] KOG3145 Cystine transporter Cystinosin  ali  100  1MSFPVAFLLVLFLVPFTFATNNLVVRQKELEIVIGGEVSVNFQIKNHTSQSLNATRISLSQSPYISHPDAILVDNWNANVTVLGSQLVSGAILEALNCTTDGSITCPLDLEDAFARITVIRSHFLAILIQIVGWTYFFAWSISFYPQMYLNFKRKSVVGLNFDFLSLNLVGFCAYAIFNLLMYYNSHVKNEYNIVNPRSPPPVLLNDVVFAVHAFLACFITILQCLFYERDNQSVSSKCIALMIVLISFGFCSAAATVLRKIQLLSFVTSLSYIKMAVTCCKYFPQAYFNYTRKSTVGWSIGNIMLDFTGGTLDILQMILQAVNVNDWSAFYANPVKFGLGFVSIFFDIIFMVQHYVLYPNAEVPHNEYHGVDNPNPDNIARDAEQYAGDSESMESTEPIIVHD 404
2 -72.300[S] KOG2913 Predicted membrane protein  ali follow..  14  2........................................................................................KTGGLSDFADFGEEDANCTQGIQWIKDVFTDCVDTDLKLLGFIIGLISLALWLIPLFPQLWQNYKTKKCEGLSLAFLFFWLVGDTCNMLGAILTNQQPIQ-------------------KIIGVYYIIQDLVLWTQYGYYLKIYNRKRSFLESLNHQEGLPLEGILKMWPIFTSYTDMLGYIIGSMAAVCYFGGRIPQIIKNYRHSSCEGLSLTMFYIIVAANFTYGISVLLATT................................................................................. 256
3 -32.600[S] COG4095 Uncharacterized conserved protein  ali follow..  13  1............................................................................................................................MKEFTEVVGWVAVIVTTLIMLPQLISIYRSKNTKKINPFSFWILHFSFSIWLFYGYLINNIQIT--------------------TSNLIATFISTLTIYALYRYSYKPTKKWNWIPLSFVLIFVSIFFILNISGVFIAKNSSLTFAFSIIAPLITTTCFIPNILIGIKKETIKYLSLSFVIIMFAFNILWIIYFSLAI----VVYKNQANNFYIPLAFQCIALVIYGIQFYFWLFQKNKEKYSQKKIKTA.............................. 228
4 -26.800[R] KOG3211 Predicted endoplasmic reticulum membrane protein Lec35/MPDU1 involved in monosaccharide-P-dolichol utilization  ali follow..  15  28.............................................................................................................................PLISKLLGYCLVAASITVKLPQIMKIVQHKSVRGLSVVAFELEVVGYTISLAYCLHKGL--------------------FSAFGEMAFLLIQAVVFLNLFVVLTGFALGVVTNGSILTQILLYS........................................................................................................................................................... 132
5 -15.600[U] COG5196 ER lumen protein retaining receptor  ali follow..  11  2.................................................................................................................................NPFRILGDLSHLTSILILIHNIKTTRYIEGISFKTQTLYALVFITRYLDLLTFHW------------------VSLYNALMKIFFIVSTAYIVVLLQGSKRTNTIAYNEMLMHDTFKIQHLLIGSALMSVFFHHKFTFLELAWSFSVWLESVAILPQLYMLSKGGKTRSLTVHYIFAMGLYRALYIPNWIWR--------YSTEDKKLDKIAFFAGLLQTLLYSDFFYIY............................................. 205
6 -15.200[S] COG3952 Predicted membrane protein  ali follow..  11  12..................................................................................................................................PLGFLASLFFGSAFSIQWWLSKKRKEVY-APRSFWILSSIGATLMIVHGTIQSQFPVTVLH------------------------VINLIIYLRNLNITSSRPISFRATLVLMALSVVFVTLPFLYVNMEWMASPNIFHLIGCLGLAIFSGRFLIQWFYIESNNTKD-FPLLFWKIGLLGGLLALVYFIRIG----DPINILCY-----------GCGLFPSIANLRLFYKEQRSTPYLDTH................................ 223
7 -14.200[U] KOG3106 ER lumen protein retaining receptor  ali follow..  10  2.................................................................................................................................NIFRFAGDLSHVFAIIILLLKIWKTRSCAGISGKSQILFAVVYLTRYLDLFTTYVS-------------------LYNSVMKVLFLATSGATVYLMYVKFKATYDHNHDSFRIEFLLVPCALLSLVIN-----HEFTVMEVLWTFSIYLESVAILPQLFLVSRTGEAESITSHYLFALGSYRALYLLNWVYRYMVESHYDLI---------AIFAGVVQTVLYCDFFYLY............................................. 198
8 -11.900[R] KOG2489 Transmembrane protein  ali follow..  9  285............................SVNIVDDHSQWQKGAIPPPLDKDVKFALFFNNYWNLGADYMPINETVKELKLSVTFYPLSIFKYQMYASQNMRSQWSDYLHTEKEDDVALLETNPILLGVTIAVSLLHTVLEFLAFKNDIQFWRSRKDLVGLSVRSVLFNIFQSLIVFLYMVKFSVGAGLLIECWKIPKVMNVEFDRTNPILGVIPRLKFSDKGSYVESDTKVYDQMAFRYLSWVLFPLLVGYAVYSIIYVEQRGWYSW--VLNMLYGYLLMFGFIPQLFINYKLKSVAHLPWRMLTYKFINTFIDLFAFVIKMPLLYRIGCFRDDIIFL-----------IYLYQRWIYRVDPTRMNEYGTSGEHEHGVPEPVEGTETAKSDTPAIEES...... 666
9 -7.450[F] KOG1479 Nucleoside transporter  ali follow..  10  71..................................................................................................................................LLGIGTMTPWNFFVTAEDYWKYKFRNAS-LQKSFTCDLALTATISGTTFLLLNAIFGHHVSLRTK------------MLGTLWMILILFGVTTGFVEINTDTWQEQFFLITLIIVVLLNISAATMS------------------GALYGVAGLFPS---EFITAVVSGQAL-------GGILTALAFILVLAFDTGTTAFIFFIVGGVLILLCIVCYVILARKPFFRYYLEGGDKYKVIRAVPSHNRNGSAEGLPLEPI............... 302
10 -6.820[S] KOG2568 Predicted membrane protein  ali follow..  6  81..................................KQGEIIRIPSPHDPQWPILLPVRFKGKRSSAKMADTEILITKTGIYNLLFISCDPQLKGLKMTGKTVWKNP--------YLPGRMAPLVNFYVYMSLAYLLLSAVWFFQYL-------FRMDILPLQHCITAVILLGLLEMLFWYLDYAN-------FNHTGMRPLALTTWVVTIGALRKTVSRILILCVSMGFGVVKSTLGGLTSKVLLVGVTYFIASEILDIAEHVGFLDAFLILWIFTSLSKTLEQLQMKRTSVKLEIYRKFSNALAVMVVASVAWIVYEVYFKATDPFN------QTAWTITAFWDVIAFLLLCIICYLWTPSQNSQRDANMKLMMDRYAYSGDVDEENEEAQSLTGGKQ...... 440
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 2 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.