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Query: [K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MQSEESHELTDGISEEKESKETMKSQKADRKKKKLKEKLLKEASKADNRGVCYLSRIPPHMDHVRLRHILAQYGELGRIYLAPEADTFVYCYSDSEAQVHRKRAGGFRGQRFSEGWVEFAKKSVAKRVADMLNGEQIGGKKKSSVYYDIWNIKYLTKFKWDDLTEEIAYKSAIREQKLNMVLSAAKREKDFYLSKIEKSRAMTEIDARMEKKRKIQEESGSNAEAAPVFPPRAIFQFRQKKSIENETSQSKPGLSTDFLASVFGGSLast
1 -103.000[K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif)  ali  100  1MQSEESHELTDGISEEKESKETMKSQKADRKKKKLKEKLLKEASKADNRGVCYLSRIPPHMDHVRLRHILAQYGELGRIYLAPEADTFVYCYSDSEAQVHRKRAGGFRGQRFSEGWVEFAKKSVAKRVADMLNGEQIGGKKKSSVYYDIWNIKYLTKFKWDDLTEEIAYKSAIREQKLNMVLSAAKREKDFYLSKIEKSRAMTEIDARMEKKRKIQEESGSNAEAAPVFPPRAIFQFRQKKSIENETSQSKPGLSTDFLASVFGGS 266
2 -36.500[R] KOG4208 Nucleolar RNA-binding protein NIFK  ali follow..  18  2............................................AAFSRSAGPILSLNP-QEDAELQKEVAQCDTVTRFRLS---------------------RKKRTGNSKGYAFVEFESEDVAKIVTETMNSYLFGERLL--------ECHFMPPEKKMESISKTNHRMSTKGQVLRKKKKKVLGTPD............................................................................ 117
3 -27.000[R] KOG0114 Predicted RNA-binding protein (RRM superfamily)  ali follow..  15  2....................................NKRNHIRLPPEVNRLLYVRNLPYKITSDEMYDIFGKFGAIRQIRV------------------------GNTPETRGTAFVVYEDIFDAKNACDHLSGFNVCNRYLV........................................................................................................................... 84
4 -26.900[A] KOG0121 Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily)  ali follow..  11  16...................................KGSRSEQERSLRDSCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMG---------------------LDKYKKTPCGFCFVEYYVRSEAEAAMRFVNGTRLDDRLIR........................................................................................................................... 102
5 -26.300[R] KOG0130 RNA-binding protein RBM8/Tsunagi (RRM superfamily)  ali follow..  16  25.RLKEKAKHRKGRGFGSDSNTREAIHSYERVRNEDDDELEPGPQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLD---------------------RRTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQ........................................................................................................................... 145
6 -24.500[A] KOG4209 Splicing factor RNPS1, SR protein superfamily  ali follow..  12  32...NEIEEEQKKLKAIQNEMVGHMNLNTSSQSNSSQSLLTPEEKAEADAKSVYVGNVDYGATAEEIEQHFHGCGSVSRVTIQ---------------------CDRFSGHPKGFAYVEFTEKEGMQN-ALAMTDSLLRGRQIK........................................................................................................................... 149
7 -24.400[J] KOG0122 Translation initiation factor 3, subunit g (eIF-3g)  ali follow..  11  165.FIDKPPTGESSTMSAAPGTGKAAYVPPSMRAGADRSAVGSDMRRRNDENSVRVTNLSEDTREPDLMELFHPFGAVTRVYVA---------------------IDQKTGVSRGFGFVNFVSREDAQRAINKLNGYGYDNLILR........................................................................................................................... 285
8 -23.700[A] KOG0108 mRNA cleavage and polyadenylation factor I complex, subunit RNA15  ali follow..  19  2............................................SMTAGNVVFVGNIPYDVSEQQMTEIFNQVGPVKTFKLV---------------------LDPETGSGKGYGFCEFFDSETTAMAVRKLNNSELGPRKIR........................................................................................................................... 79
9 -23.300[J] KOG0899 Mitochondrial/chloroplast ribosomal protein S19  ali follow..  14  24..........WVYRFQASSMAFCTKLGGHWKQGVNVPVSSMLGSLRYMSTKLYIGGLSPGTDEHSLKDAFSSFNGVTEARVM---------------------TNKVTGRSRGYGFVNFISEDSANSAISAMNGQELNGFNIS........................................................................................................................... 135
10 -22.200[A] KOG4207 Predicted splicing factor, SR protein superfamily  ali follow..  14  4.......................................GRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIP---------------------LEPHTKAPRGFAFVRFHDRSDAQDAEAAMDGAVLDERELR........................................................................................................................... 86
11 -22.000[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  12  144..EAASEEKAGQVGGAGSIPGQYVPPSRRAGARDPSSDAYRDSRERDDMCTLKIMQVNENADENSLRELLFPFAPIPRVSVV---------------------RNKETGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILR........................................................................................................................... 264
12 -21.900[R] KOG0125 Ataxin 2-binding protein (RRM superfamily)  ali follow..  16  66...QAHGEQSSNSPSTQNGSLTQTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFN-----------------------ERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIE........................................................................................................................... 182
13 -21.700[A] KOG0107 Alternative splicing factor SRp20/9G8 (RRM superfamily)  ali follow..  13  4...................................................VYVGNLDPRVTERELEDEFRSFGVIRSVWVARRPP--------------------------GYAFLDFEDSRDARDAIREVDGKNGWRVEQS........................................................................................................................... 69
14 -21.400[A] KOG4206 Spliceosomal protein snRNP-U1A/U2B  ali follow..  12  110.QEEKVERKREDSQRPNTANGPSANGPSANNGVPAPSFQPSGQETMPPNNILFIQNLPHETTSMMLQLLFEQYPGFKEIRMIDAKP--------------------------GIAFVEYEDDVQASIAMQPLQGFKITPQN--------MVISFAKK............................................................................................................. 232
15 -21.200[A] KOG1190 Polypyrimidine tract-binding protein  ali follow..  6  10VGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGK---------------------------NQAFIEMNTEEAANTMVNYYTSVTP................................................................................................................................. 119
16 -21.200[A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)  ali follow..  23  4...................................................VYIGRLPNRASDRDVEHFFRGYGKLSDVIM-----------------------------KNGFGFVDFQDQRDADDAVHDLNGKELCGERVI........................................................................................................................... 66
17 -20.800[A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily)  ali follow..  18  5........................................ADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELK------------------------NRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLR........................................................................................................................... 83
18 -20.800[R] KOG0226 RNA-binding proteins  ali follow..  10  146LLRTQALQSDIDKMNFKKQTDPFKKKIKEQQAKKKFVRSGGGQVWEDPS--VFCGDLGNEVSDELLAKAFRKYPSFQKAKVV---------------------RESRTNKSKGYGFVSFRDSEDYVRAMREMDGKYVGNRPIK........................................................................................................................... 275
19 -20.500[R] KOG4454 RNA binding protein (RRM superfamily)  ali follow..  15  2......................................EIKPTPSPPEERTIYVANFSEEVDEELLEELFIQAGPVVKVILRDV-----------------------RDSNAKFALVEFEDELSVLFAIELMNGVRLFNQELQ........................................................................................................................... 83
20 -20.400[R] KOG1457 RNA binding protein (contains RRM repeats)  ali follow..  15  83.......................................VHELKTRPGVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLI-------------------------KLTARQPVGFVIFDSRAGAEAAKNALNGIRFDPENPQ........................................................................................................................... 161
21 -20.300[A] KOG0146 RNA-binding protein ETR-3 (RRM superfamily)  ali follow..  9  5MATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVL---------------------KDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNR........................................................................................................................... 126
22 -19.600[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali follow..  16  5..................TKVKLINELNEREVQLGVADKVSWHSEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLV---------------------RDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIR........................................................................................................................... 108
23 -19.500[K] KOG1548 Transcription elongation factor TAT-SF1  ali follow..  9  61TEGKESSNGEDRHTKRLYESTSAEGYPSGSRNKKSKSENSEASPAPVINKAVYIQGLPLDVTVDEIEEVFKKCGVIAKNIDNGTPR---------------KIYRTEDGTPKGDALIVFFRSESVELAEQLFDDTEFRYGSGQ........................................................................................................................... 189
24 -19.300[A] KOG4212 RNA-binding protein hnRNP-M  ali follow..  15  604IERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKME-----------------------NGKSKGCGVVKFESPEVAERACRMMNGMKLSGREID........................................................................................................................... 723
25 -18.800[A] KOG0144 RNA-binding protein CUGBP1/BRUNO (RRM superfamily)  ali follow..  14  385.....................................GAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVF---------------------IDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLK........................................................................................................................... 469
26 -18.700[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  12  177YEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLA---------------------RDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR........................................................................................................................... 298
27 -18.400[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  12  1MESNHKSGQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF----------------------NGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCAS---VGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFN.. 252
28 -18.400[A] KOG0120 Splicing factor U2AF, large subunit (RRM superfamily)  ali follow..  14  158FDGINLKGQSLKIRRPHDYQPMPGITDTPAIKPAVVSSGVISTVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLV---------------------KDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLI........................................................................................................................... 279
29 -18.300[K] KOG2068 MOT2 transcription factor  ali follow..  10  60YDKEKIVGMTVDQERLASEGNMDRKKIQKSKPKSSDGRKPLTSVRVVQRNLVYIVGLPLNLADEDLKEYFGQYGKVLKVSMSRTATGL----------------IQQFPNNTCSVYITYGKEEEAIRCIQSVHGFILDGKALKACFG---TTKYCHAW------VACNNQDCLYLHEVGSQEDSFTKDEIISAHTRVQQITGATNTMQYRSGSMLPPPLDAYTSDSSTGNPIAKVPSSTSVSAPKSSPPSGSSGKSTALPA..... 301
30 -18.300[R] KOG0110 RNA-binding protein (RRM superfamily)  ali follow..  13  318...DFTEKNKVTKASKSGQPLAPAAVDAGNAKWKHQQDSLSKEDDISESGRIFFRNLAYTTTEEDLRKLFEQFGPVVEVNLP---------------------LDKLTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLH........................................................................................................................... 436
31 -18.100[AJ] KOG0148 Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)  ali follow..  12  54........HEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPQITTEDIKAAFAPFGRISDARVV---------------------KDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR........................................................................................................................... 167
32 -17.800[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali follow..  8  639MENDQKAQQALLKDRVPVKGRPMFISANDPEKRVGFKFSTTLEKSK-----VFVRNVHFQATDDELKALFSKFGTVTSVRRVTH----------------------KDGKPKGIAFVDFDTEASAQKCVASGDKLMLRERELE-----------------------------------------VALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRAITNKTPQITARLDAMDVSEGTSTSQPLSNDQFRKMFMKN 836
33 -17.700[A] KOG0145 RNA-binding protein ELAV/HU (RRM superfamily)  ali follow..  15  299...................................................IFVYNLSPDSDESVLWQLFGPFGAVNNVKVI---------------------RDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ........................................................................................................................... 369
34 -17.700[R] KOG0118 FOG: RRM domain  ali follow..  12  126..RNNGFAGTGNGGYGNENGGFRRKKSFGQGKRRMNARTSMAQREDVIRRTVYVSDLDQQVTEEQLAGLFVSCGQVVDCRICGD-----------------------PNSVLRFAFIEFTDEEGAMT-ALNLSGTMLGFYPVK........................................................................................................................... 242
35 -17.500[K] KOG4210 Nuclear localization sequence binding protein  ali follow..  13  190FKNVEQMKAVLELSESHLNGRNMLIKDSENYSGRPDKDDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMA---------------------TFEDSGKCKGFAFIDFKNEEGSTNELKDKSCRKIAGRPLR........................................................................................................................... 311
36 -17.100[R] KOG0149 Predicted RNA-binding protein SEB4 (RRM superfamily)  ali follow..  16  2...........................AYQPVPGSGFHYLNSPFGDTTFTKVFVGGLAWETQSETLRQHFEQYGEILEAVVIAD---------------------KNTGRSKGYGFVTFRDPEAARRACAD-PTPIIDGRRANC.......................................................................................................................... 96
37 -17.000[K] KOG0147 Transcriptional coactivator CAPER (RRM superfamily)  ali follow..  18  198FCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLM---------------------KDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR........................................................................................................................... 319
38 -15.900[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  21  184...PNEPDDPLCEQNIKDRYYGRNDPVAEKIMKRAASLPTLEPPEDRNITTLYVGNLPEEITEPELRDQFYQFGEIRSIALVPRQ---------------------------QCAFVQYTKRNAAELAAERTNKLVIQGRKVS........................................................................................................................... 297
39 -15.700[A] KOG0131 Splicing factor 3b, subunit 4  ali follow..  11  10..................................GANLLGQHSAERNQDATVYVGGLDAQLSEELLWELFVQAGPVVNVYVP---------------------KDRVTNLHQNYGFIEYRSEEDADYAIKVLNMIKLHGKPI-------------------------------RVNKASQDKKSLDVGANLFIGNLDPDVDEKLLYD--------FSAFGVIASNPKIMRDPDTGNSRGFGFISYDSFEASDAAIESMTGQYLSN. 181
40 -15.600[TR] KOG4019 Calcineurin-mediated signaling pathway inhibitor DSCR1  ali follow..  11  2........................................EEVDLQDLPSATIACHLDPRVFVAKFESLFRTYDKDITFQYFK---------------------------SFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYF........................................................................................................................ 85
41 -15.600[AJ] KOG0123 Polyadenylate-binding protein (RRM superfamily)  ali follow..  9  60..........QQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD-----------------------ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSK---SYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN-DDTIDDEKLRKEFS.. 315
42 -15.500[R] KOG4733 FOG: RRM domain  ali follow..  9  22.........LQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAI---------------------LDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNL-YISNLP-QELENMLKPFGQVISTRILRDSSGTSR---RMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPN........................... 235
43 -15.300[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  10  67AQQPYDNNGGHRSGGGGGRSGGGGTSFNGAAFTESQLMDEVPKKKFTGRCRLFVGNLPNEVKETELKELFSPHGDIAECYLS----------------------------GKGFAFLRLDTRAHAESAKEAIDGRIIHGRQVRVRFAV-IRVKELSPTVSNEMLYH-AFSHFGDVERAVHIVDEKGRPTGEFERKPNCNEAMAAIRDK.......................................................... 252
44 -15.100[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  12  410...................................................IFVRGFGWDTTQENLKTAFESYGEIEECSVVMD---------------------KDTGRGKGYGFVMFKTRKGAREALKRPE-KRMYNRIVVC.......................................................................................................................... 480
45 -14.600[A] KOG0533 RRM motif-containing protein  ali follow..  12  26.QKKSFGGARRGNTRPTGLPRRSGGSGGWKDLDAVQNHGISSRGNDSKVIRVNISNLAPTVISSDLEELFGDYR-LSSVSVN-----------------------NEHGDSLGTGDISLTKRD-AERLVQKFSGVALDGKIMK........................................................................................................................... 143
46 -13.900[AR] KOG1365 RNA-binding protein Fusilli, contains RRM domain  ali follow..  9  128EEIEDDVAIARAILDMDDELLEKTHQFVNIEYQPAPILEDQEVGADGDNVVCRARGLPWQASDHHVAQFFAGLDIVPGIALCLSS----------------------EGRRNGEVLVQFSSQESRDL-ALKRHRNFLLSRYIEVYKAGIVRMRGLPYDCTDAQIRTFFEPLKLTDKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEEKKKDCVIVTFLGD. 407
47 -13.700[R] KOG1995 Conserved Zn-finger protein  ali follow..  12  232.APSTGGRGGRSGGYDGGSAPRRQEASYEDAATEKVKQCDADCDDNCDNARIYISNLPPDVTTDELKDLFGGIGQVGRI---------KQKRGYKDQWPYNIK-TDEKGNYKGDACLAYEDPSAAHSAGGFFNNYEMRGNKIS........................................................................................................................... 365
48 -13.300[T] KOG0116 RasGAP SH3 binding protein rasputin, contains NTF2 and RRM domains  ali follow..  11  229.GATFNAKASPAKPKSKPVTKPSAARESKAPAPVSEHSSAATIDQQAEGYTIFVANLLMDATPEQLNETFKGFGAITKDGIQ----------------------RSYRLKGNCFGFVTFASAEAVKLVAHKESAIRIGNRRVS........................................................................................................................... 351
49 -13.200[J] KOG2314 Translation initiation factor 3, subunit b (eIF-3b)  ali follow..  7  9.VLTAQLGINWSDVNLDSIQLPPGNDFGIESDDESVYQDDQSEFDTGFGNIIVVDHLP----EGVVKKIYNQLGVIKENGLL-------------------MPVDPDTKMTLGYCFIEFNTPQEAQNAKEKSHGYKLDKS.............................................................................................................................. 134
50 -13.200[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  9  45.SGGGGGGTPSADGAAGPGSGEPGERNSGGPNGVYHQSSGSLTPTMNRRYQLYVGNLTWWTTDQDIANSLRDIGDLQEVKF---------------------FENRANGQSKGFSVISLGSESSLRAVLDQLPKKEMHGQA............................................................................................................................. 165
51 -13.000[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  9  83...............................................................EDLFEELGKFGEIESLNICDN----------------------LADHMIGNVYVQFKEEDQAAAALQALQGRFYSGRPI--------IADFSPVTDFREATCRQYEENNCNRGGYCNFMHVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRDPSHREFSHRDRDREFYRHGSGKRSSERSE......... 246
52 -12.600[R] KOG2295 C2H2 Zn-finger protein  ali follow..  11  467.IKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIAD----------------------LVERRWYRRGWITFMRDVNIKEICWGLNNQRLRD............................................................................................................................... 583
53 -12.500[A] KOG1996 mRNA splicing factor  ali follow..  12  268........EKTSKRGGKIIVGDATEKGEAQDASKKSDSNPLTEILKCPTKVVLLRNMAGEVDEDETKEECEKYGKVGKCVIFEIPGAPDDEA-----------------------FLEFERVESAIKAVVDLNGRYFGGRVVK--------ACFYNLDKFRV........................................................................................................ 398
54 -12.300[A] KOG4205 RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1  ali follow..  12  6..........STGATAVATLRETSPPVDGHEEARLNADSDDGSHGSQDPGKMFIGGLSWQTTAENLRDYFGRFGEVNECMVMRD---------------------PATKRARGFGFITFVDPSSVDKVLNELDGKKIDPKV............................................................................................................................. 119
55 -12.200[A] KOG4211 Splicing factor hnRNP-F and related RNA-binding proteins  ali follow..  10  5...........................................TEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGIRFI-----------------------TREGRPSGEAFVELESEDEVKLALKK-DRETMGHRYVE-------------------VFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIE...... 182
56 -12.000[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  13  823.DGGFRGGFRGGYRGRGGGRGGFQGGSRGDDSQPSQSELMELIKSIGPRGVLSCNGFPKDVTLEDVVEFFNDYE--NSIRI----------------------RRGDDGVMTGECMLACQNQENARRASMDLDGQKLRNSVIS........................................................................................................................... 944
57 -11.800[A] KOG4676 Splicing factor, arginine/serine-rich  ali follow..  17  34..................................................VIQVTNVSPSASSEQMRTLFGFLGKIDELRLFP-------------------PDDSPLPVSSRVCFVKFHDPDSAV-VAQHLTNTVFVDR.............................................................................................................................. 103
58 -11.800[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  8  123.IRERRNQDRENSRDHNSDNTSSSRFDELPDYFDPSGRLGSLDDGDPQTTNLYVVNLSSKVDENFLLRTFGRFGPIASVKIMWP------------------RTEEEKRRERHCGFVAFMNRADGEAAKEKMQGIIVYEYELK........................................................................................................................... 246
59 -11.700[A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)  ali follow..  14  54.PLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLI---------------------HDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVL........................................................................................................................... 174
60 -11.500[K] COG5175 Transcriptional repressor  ali follow..  14  81YDDENVRYVTLSPEELKMERAKLARKEKERKHREKERKENEYTNRKHQKNLVYVVGINPPVPYEEVEKYFGQYGKINKIVVNRKTPHSNNTT----------SEHYHHHSPGYGVYITFGSKDDAARCIAQVDGTYMDGRLIKAAYG---TTKYCSSY............................................................................................................ 238
61 -11.400[R] KOG2135 Proteins containing the RNA recognition motif  ali follow..  12  359..........................................GAINRDNCTLQVAKIPP-NTIAKLNEHFATFGTVDNIQVRYNGEIDS-------------------------ALVTYASKFDAGKAYKSLNNRFI-------------KVFWHNPGGEGSENATGKPSSPTSPPKPVEKPKIATVQESKFVSVAAQNYRKQIQDAKERLTKEKSILSTLVQAQNQHNIILDKWMVKQKELLIKARTSTDETDKKNATKLV.... 545
62 -11.000[D] KOG4660 Protein Mei2, essential for commitment to meiosis, and related proteins  ali follow..  15  230.........DIRAAHAAMRALQNTLLRKRTLDIHFSIPKENPSEKDMNQGTLVIFNVDTTVSNDELLQLFGAYGEIREI--------------------------RETPNRRFHRFIEYYDVRDAETALKALNRSEIGGKCIK........................................................................................................................... 337
63 -10.200[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  12  358.DFDACNEVPPAPKESSTSEGADQKMSSPEDDSDTKRLSKEEKGRSSCGRNFWVSGLSSTTRATDLKNLFSKYGKVVGAKVV---------------------TNARSPGARCYGFVTMSTAEEATKCINHLHKTELHGKMIS----------------------EKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDGSGEKSKDQDDQKPGPSERSRATKSGSRGTERTVVMDKSKG......... 571
64 -10.100[J] KOG0129 Predicted RNA-binding protein (RRM superfamily)  ali follow..  8  419.............EDGFLDDGRGDQPLHSGLGSPHCFSHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKA-------------------ESKSYFPPKGYAFLLFQDESSVQALIDA--------------------------------------------------------------CIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGG. 589
65 -9.810[A] KOG4008 rRNA processing protein RRP7  ali follow..  11  39..........................................KKDPSKENSIIVSNIPAFVGEGVVLAIIDQFASFEVEESFVQRSN---------------TADNSLSQGQLTMSITFDKPEAVIQTLALCQDV---------------GPFTITDFLEDPEFPSVLKDSTTLYRKLFPSEEQIQEMADTYVERYDTEQTEAR--KEAKRKYSEPDEDGWITVTKAKKAAKSVKLKKEDVPLIGGLNNKKKKVDLAYYT...... 224
66 -9.390[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  13  176.WSSSNRHSRRRRSRSYSRERDRNSRRDDRRSNLSNNDRYSDWNPGVPSNKLAILNMPNDVDNTKITLSLGKCGYLPQ------------------DVRTMTKFDKNTKQIRTFAFVEFSNRETAEQWMTDYEGWLT................................................................................................................................. 293
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;