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Query: [DL] KOG3194 Checkpoint 9-1-1 complex, RAD1 component, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFQAETVCLKQIQSTLRCIDFSKECTIEITSRGLRFAVEESQSLQAHAFLDKSLFQTFNFQGDSDGDTYMFQTMISPLLQSLSIYTDGKERISTSAWDQPTVNIMHKRGVICKVQYNGPGCPFIWEVEEMAGYATACELLTMECEDDVDINRLASTLCTKIIMKSNWLYDALVELDNNMGENLIIHTSSQKSTFLLRCVGALSTTEIEYPNEKSVLESFETDSENTYSYRFSLIRHALKALQVGSKVNLRIDENGTLSIQIMLVGQEGLCTFVDFCIVPLDLVSEDEEEDEEEEPAESNQSDNNVLRNDPNYRGDAETEDEDSLast
1 -111.000[DL] KOG3194 Checkpoint 9-1-1 complex, RAD1 component  ali  100  1MFQAETVCLKQIQSTLRCIDFSKECTIEITSRGLRFAVEESQSLQAHAFLDKSLFQTFNFQGDSDGDTYMFQTMISPLLQSLSIYTDGKERISTSAWDQPTVNIMHKRGVICKVQYNGPGCPFIWEVEEMAGYATACELLTMECEDDVDINRLASTLCTKIIMKSNWLYDALVELDNNMGENLIIHTSSQKSTFLLRCVGALSTTEIEYPNEKSVLESFETDSENTYSYRFSLIRHALKALQVGSKVNLRIDENGTLSIQIMLVGQEGLCTFVDFCIVPLDLVSEDEEEDEEEEPAESNQSDNNVLRNDPNYRGDAETEDEDS 323
2 -66.600[L] KOG1636 DNA polymerase delta processivity factor (proliferating cell nuclear antigen)  ali follow..  11  1MLELRLVQGSLLKKVLESIKLVNDANFDCSSTGFSLQAMDSHVALVSLLLRSEGFEHYRCDRN-----LSMGMNLGNMSKMLKCAGNDDI---------------------ITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDT---VVISVTKEGVKFSTAGDIGTANIVLRQNTEDAIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYKV----AEMGYIRYYLAPKIEEEEDTN................................... 262
3 -37.400[DL] KOG3999 Checkpoint 9-1-1 complex, HUS1 component  ali follow..  3.FKTRISNLYTLTRLVQALDIGRFCWLRLMPETVNFVIVPFRMTQVWSVLEVETIFEDYVVQSNADNVINLEVPIDNFYKALRSAANASDSTVRLSKKNNQPLL------SLSTTWSGRAFGSNIVTHN-----IPVRVLSQSYVSVIKEPTAPEPDCHIFLPQLNFLRHVVDKYKSLSDRIIM---ANMSGELQLSVNIPSARVSTKWKGSRHPSQTRAPEEFVHMRLDSKDLVNMLKISSVAKRVIACFCEGHALVLYVYIDPEDEHTAVLTYYISTYVD......................................... 287
4 -28.700[DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component  ali follow..  11  3.YTLEGSNARVIAKAVQSLSVGKEMFIEIDQQSLQMRAINTQSAVGSISFKRSMFEVYDMPPH---SDFYCKISMKGCLAVFRNMNEVEY---------------------CELNLLDNQTNLQVNLRCKLETTKEATI-SIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEE---LTLEANSGSVVAKNYIEGARMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLAECLNASLTLEFDEAGPFLLKI----KKHGEIECLLIMSTLSPDDISFSEDYCQKDLTVQDEDVRAAAAKRKSSVSKPNVTNKR 301
5 -5.130[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)  ali follow..  13  130.......PAEQLKTMLQRTSFAEESRYVLT--GVLLAIANGVATIVGTDGKRLAKIDAEVTLDKSFSGEYI-IPIKAVEEIIKMCSDEGEAAIFLDQD--------------KIAVECDNTLLITKLLSGEFPDFSPVI--------------STESNVKLDLHREELITLLKQVALFTNESSSVKFSFLPGELTLTANCT------KVGEGKVSMAVNYSGELLEIAFNPFFFLDILKHSK-DELVSLGISDSYNPGI--------TDSASGLFVIMPMRLHDD...................................... 366
6 -5.000[S] COG5619 Uncharacterized conserved protein  ali follow..  1..................................................................................................................................................................MNHLALTSYLGTLAEVG------FVNEFRQVVPTRTTNITTIEVGDTSKISGDETGADIAEGSTIHY---------LACLRQAKYSCILFDGSLVQLKYSTCEGRITNHRYLYFPCPAKLDLRSTADETIYDIVDDACLAGAL.................. 128
7 -4.130[K] KOG3334 Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA)  ali follow..  12  10......RDAKVISVILRSLGIEE-----CEPKVIIQLLEFAYRYTTDVLEDALLFAKHTGRTHITTSDVKLALQ......................................................................................................................................................................................................................................................... 72
8 -4.130[K] COG5094 Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA)  ali follow..  12  10......RDAKVISVILRSLGIEE-----CEPKVIIQLLEFAYRYTTDVLEDALLFAKHTGRTHITTSDVKLALQ......................................................................................................................................................................................................................................................... 72
9 -4.040[S] KOG2592 Tumor differentially expressed (TDE) protein  ali follow..  10  165...........LIQLVLLIDFANESWVEKMEEGAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNM-----LLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTVKISSSWIGIVLYVWT-----------LVAPLVLTNRDFD................................... 453
10 -4.000[R] COG0670 Integral membrane protein, interacts with FtsH  ali follow..  138...........MFALFIVLLLGMVASFFFQIPALSVAISALFVVFSTMTI---LYETSNIIHGGETNYIRATVNI--YVSIYNLF.............................................................................................................................................................................................................................................. 206

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 5 5 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.