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Query: [C] KOG3378 Globins and related hemoproteins, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFNCSISLIILFAVLSTVAGDRGICAQEKLDLESCAQPHKEYIHSLSDVTGREIHNPKFMKKFVEFTKTASSCIGSNVTCDASRHYRFFLDSLTNMGNILYQESNLDCLKNIAPTFRFCYRQARMTYNTLVDVSRIVRKMTKFTDCLRKELVARNVCTRDSVKNINVAVKIIRNLVRQYEKWTNGEMVPMPDLRAEMPATCPFKGNPPSGPQSPAVQSPLFGRFQKKISNFSIFILFSSVSDLNNPDAKIKMRQEMDRITERQKHIFTETFPVIFKEYKRNGLVLFAKYFSEFPHYKNIWPQFRTLQDSALLASNELANHCSVYMSGLKVLast
1 -121.000[C] KOG3378 Globins and related hemoproteins  ali  100  1MFNCSISLIILFAVLSTVAGDRGICAQEKLDLESCAQPHKEYIHSLSDVTGREIHNPKFMKKFVEFTKTASSCIGSNVTCDASRHYRFFLDSLTNMGNILYQESNLDCLKNIAPTFRFCYRQARMTYNTLVDVSRIVRKMTKFTDCLRKELVARNVCTRDSVKNINVAVKIIRNLVRQYEKWTNGEMVPMPDLRAEMPATCPFKGNPPSGPQSPAVQSPLFGRFQKKISNFSIFILFSSVSDLNNPDAKIKMRQEMDRITERQKHIFTETFPVIFKEYKRNGLVLFAKYFSEFPHYKNIWPQFRTLQDSALLASNELANHCSVYMSGLKV 330
2 -15.400[C] COG1017 Hemoglobin-like flavoprotein  ali follow..  2..................................................................................................................................................................................................................................................................LDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFNM----------SNQRNGDQREALFNAIAA 63
3 -7.940[C] KOG3458 NADH:ubiquinone oxidoreductase, NDUFA8/PGIV/19 kDa subunit  ali follow..  13  27.............LRAGAFHLGKQCEQANNEFMLCRQELDD-------------------RACLAEGKAVTSC-----------------------ALDFFRKVKKTCHEEFTQ-YATCLDK----SSGTMAFSHCRKTQGVFDKCIKDNF................................................................................................................................................................................... 118
4 -7.710[R] KOG4729 Galactoside-binding lectin  ali follow..  50................LRSNRVQACDGERITL-SCPRNTQISVQTGFYGRVVP--PQAGRKHSEANLDPLSMIHHSSTLCDKRRKCTVVVDSNTFEDDPCYLQMAYGCIPMSFDEETFCTPKPTDHECVSDVLPQVLRQCHAKEGCTLKSDGIKGHCRHGHLHVVYVCVNE--EIFSEEAIKGELTSLETYLKVRPEADAMQKQDDERFFKDVNDKTQWERVVDSEPAKDPDVHQIANDASYVTHDEYRMEKQDPPPITERVEPNLVLQVVQFFKENKEKAVMCIVLAV......................................... 376
5 -7.650[OU] COG5082 Arginine methyltransferase-interacting protein, contains RING Zn-finger  ali follow..  65.......................NCSQRGHLKKDCPHIICSYCGATDDHYSRHCPKAIQCSKCDEVGHYRSQC--KKVQCTL-------------------------C-KSKKHSKERCPSIWRYILVDDNEKAKPKVLPFHTIYCCGGKGHFGDDCKEKRSSRVPNEDGSAFTGSNLSVELKQEYYRHMNRNSDENEDYQFSESIYDEDPLPRPSHKRHSQNDHSHSGRNKRRASNFHPPPYQKSNVIQPTIRGETLSLNNNIS................................................................. 285
6 -6.600[R] KOG0490 Transcription factor, contains HOX domain  ali follow..  11  2.....................MVHC-------AGCERPILD----------------RFLLNVLDRAWHI-KCV----QCCECKTNLFSREGKLYCKNDFFRRFGTKC--------AGCAQGISPSDLVRKARSKVFHL--NCFTCMV--------CNK---------------------QLSTGEELYVIDENKSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQL............................................. 213
7 -6.470[S] KOG4695 Uncharacterized conserved protein  ali follow..  12  50..SCTQELQALFGCLKKWEFDDVPCSKQHTLYMDCVHKGAEEAAAYRDATRKGTMTSAQFNKIQKLFPQ-------------PDLGKQPYRQMKRLPTQDYADDTFH............................................................................................................................................................................................................................... 152
8 -6.190[K] KOG4577 Transcription factor LIM3, contains LIM and HOX domains  ali follow..  16  8..PAEGAVKGLPEMLGVPMQQIPQC-------AGCNQHILD----------------KFILKVLDRHWH-SSCL----KCADCQMQLFSRAGSVYCKEDFFKRFGTKC--------TACQQGIPPTQVVRKAQDFVYHL--HCFACI--------ICNRQ.......................................................................................................................................................................... 123
9 -5.800[C] COG0348 Polyferredoxin  ali follow..  12  186.............LFDLFIVEHGWCG--------C--PIGAAYG--------VIGAKGLFRIKVEHRQQCDNCMDCYNVCPEPQVLRDPLHAKKSESPLVLSKDCISCGR--------CIDVCPEKVFIFTTRFNHSVNHSG............................................................................................................................................................................................ 290
10 -5.780[DKL] COG5220 Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3  ali follow..  1............................................................MDDEGARKVDEKC----PLCQADR----------YLNPNMKLLINPECYHKM------C-------------------------SCVDRIFTTGPGCNKILRKAKFREQTFEDAQIEREVDVRKRISRIFNKGQQEFDSLQAYNDYLEEVEIYKIDVEETEEKVKQYEKQNRDSIAANSARAAAEARILAQNEILLKRQKQEAREAAIREHQKEKERREQVEQQIIFDLATSGKDPNKIIQLSDSLKKQQENIASSVSN........... 227

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.