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Query: [J] KOG3409 Exosomal 3`-5` exoribonuclease complex, subunit ski4 (Csl4), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSEQQDETVVCLPGERLCRTEDSIVLGIGTYEQNGYIYASKSGIVNIEDSGDKCQVVSVHKPGFHLTIPATGDVVTARVLVTTPKFAKCAIFCVRNVLLESSYRGLLRKEDVRETEKDRVDIYKSFRPGDVILARVINQLEQSFLLTTAENELGVVIAYASDYRKTRVPMVPVGWSEMQCPQTTIKEPRKVAKVLPESSINAVKLast
1 -97.000[J] KOG3409 Exosomal 3`-5` exoribonuclease complex, subunit ski4 (Csl4)  ali  100  1MSEQQDETVVCLPGERLCRTEDSIVLGIGTYEQNGYIYASKSGIVNIEDSGDKCQVVSVHKPGFHLTIPATGDVVTARVLVTTPKFAKCAIFCVRNVLLESSYRGLLRKEDVRETEKDRVDIYKSFRPGDVILARVINQLEQSFLLTTAENELGVVIAYASDYRKTRVPMVPVGWSEMQCPQTTIKEPRKVAKVLPESSINAVK 204
2 -77.600[J] COG1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain)  ali follow..  23  8.KKTIKNGDFVLPGDYLGVIEE-YLPGEGVIVEDGNLYSARAGWVKINKDK---VEISLEPASSVPPIPKKGDIVYARVIDVKQQAVLLRMIKIEGQENREIATSKLAGIHISQVKDGFVDLRNEFKIGDIVRARVIADEKSPIQLTTKDPDLGVVYALCSKCRT----PLVRKGNQLVCPRCGNVETRKISTLYRKVKL.... 199
3 -52.700[A] KOG3013 Exosomal 3`-5` exoribonuclease complex, subunit Rrp4  ali follow..  22  49.FDKSIHQNLVTPGQLVTDDPQ-FMRGHGTYFEDGGIYASVAGSVQRVNK------LISVKPLRSKYVPEIGDLIIGKIAEVQPKRWKVDIGAKQNAVLMLSSINLPGGIQRRKLETDELQMRSFFQEGDLLVAEVQQYFSDSVSIHTRSLKYGKLRNGV--FLKVPPALVVRSKSHAYALAGG.................... 223
4 -42.300[J] COG1097 RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)  ali follow..  25  2......DKKIVIPGDLLS--ENQKKAGYGTYVKNDKIYSSLCGIENLKEDKVGVI------PLAGAYIPSANDVVIGIVIVVTPSNWIFDIAAPYDGLLHVS---------EYPRRVESREMPEILNVGDSVILRVKDVDSMKVELALRDPSLHKLKT.............................................. 137
5 -35.000[J] KOG1004 Exosomal 3`-5` exoribonuclease complex subunit Rrp40  ali follow..  19  1MAEVKGLLSYYFPGERIPDQDGSIRLGPGLVDREEEIVVSKAGRLHQTGKN-----AMLIDSRTKRYIPATNDQVIGQIISRFAEGYRVDIGSAHIAQLN-----------ALAFENVTRKSRPNLNVGSLVYARVSLADRDEPELECFDATTGKAAGYGELKNG....................................... 160
6 -13.100[K] COG1095 DNA-directed RNA polymerase, subunit E`  ali follow..  15  46TSQNEGKYLVISVLYTESIGEGTIVHGDGGVYQEVKYRALVY-------------------------YPEMQEIVDGEVVSVQKFGAFIKFSSFEGLLHISQIMDDRIDIDLENKRFIGKETKRDLKVGDRVRVRIVAMN-SKIGFTMKQVGLGKL................................................ 183
7 -12.600[J] COG1093 Translation initiation factor 2, alpha subunit (eIF-2alpha)  ali follow..  16  7....................................................................PEVGDLVVVKITEVKNFGANGILEEYPG------VEGYIHISEV--ATGWVKHIRSYLREGQRVVCKVINVNQERKNVDLSLKRV................................................... 83
8 -11.400[J] KOG2916 Translation initiation factor 2, alpha subunit (eIF-2alpha)  ali follow..  18  14....................................................................PEVEDVVMVNVRSIAEMGAYVSLLEYNN------IEGMILLSEL--SRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRV................................................... 90
9 -11.100[J] COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain)  ali follow..  18  4.....................................................................EVGSKLQGKITGITNFGAFVELPGGSTGLVHIS----------EVADNYVKDINDHLKVGDQVEVKVINVEDGKIGLSIKK...................................................... 75
10 -10.800[K] KOG3298 DNA-directed RNA polymerase subunit E`  ali follow..  14  82....................................................................PFRGEVVDAIVTTVNKMGFFANIGPLNVFVSSHLVPPDMKFDPTANPPNYSGE-DQVIEKGSNVRLKIVGTRTDATEITMKEDYLGVL................................................ 172
11 -9.560[J] KOG4600 Mitochondrial ribosomal protein MRP7 (L2)  ali follow..  19  78LGVKIYGDQVAKPGAIIVRQRGKFHAGKNVGIKDHTIFSLIDGLVKFEKFGPDRKKISVYP............................................................................................................................................... 140
12 -9.270[K] KOG3297 DNA-directed RNA polymerase subunit E`  ali follow..  10  30LNNKFANKIIPNVGLCITIYDLLTVEEGQLKPGDGSSYINVTFRAVV-------------------FKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFIPQNMLFEGCYYTPEESPMDEETKLYFDVNEKIRFRIEREVAYALLGSCQTDGMGLV................................................ 208
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Jaroszewski L, Li W, Godzik A. Comparison of sequence profiles. Strategies for structural predictions using sequence information. Protein Sci. 2000 Feb;9(2):232-41.