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Query: [PT] KOG3676 Ca2+-permeable cation channel OSM-9 and related channels (OTRPC family), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFPVDCPHEEGELDSCPTITVSPVITIQRPGDGSTGARLLSQDSVAASTEKTLRLYDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILILGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKIGDYFRVTGEILSVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEKLast
1 -229.000[PT] KOG3676 Ca2+-permeable cation channel OSM-9 and related channels (OTRPC family)  ali  100  1MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFPVDCPHEEGELDSCPTITVSPVITIQRPGDGSTGARLLSQDSVAASTEKTLRLYDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILILGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKIGDYFRVTGEILSVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK 839
2 -48.300[O] KOG4412 26S proteasome regulatory complex, subunit PSMD10  ali follow..  19  2....................EIATDTAKQMRDEELFKAAEWGDSSLFMSLSEEQ-----------LSKSLNFRNEDGRSLLHVAASFGHSQIVKLLSSSDEAKTVIN------------------------------------------SKDDEGWAPLHSAASIGN----------------AELVEVLLGADVNAKNNGGRTALHYAASKGRLEIAQLLLTHGAKINITDKV--------------GCTPLHRAASVGKLEVCEFLIEEG---AEIDATDKMGQTALMHSVICDDK---------QLKVSMDQVAFLLIRHGADVDVEDKEGYTVLGRATNEFRPDAAKAMLEG................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 247
3 -44.000[E] KOG0503 Asparaginase  ali follow..  13  297.STFRAFLAPPIRGVVLQSFGSGNIPSNRKDLIDELRAAGERGVIIINC-------------TQCPNGTVAEIYDTGKVLCDVGVIPGFDMTPEAALAKLAYVIGKEEWSLTSLKAPKMEDYDLVDAVARSLHLSSPQELDQ-------LGETLFPAMINAAVAEGD----------------PKKINNLKGADLSGTNHDQRTALHLACQLGNVEIVKYLLQNGVSVHVRDR--------------YDRTPLLEAVATDSHEIIQLLINCG---AHLTGSSRAVGEQLCAAAARGSMIRLKS----------------YQYAGADLAQSDPSGRTALHVAALHGFPEVVQYVLPYFENPNEKDMLGLTAMDYAERGGHAAVMEVLK.................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 630
4 -43.700[I] KOG0817 Acyl-CoA-binding protein  ali follow..  13  1.....MASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETSCLA-------------ELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFE----GKQKWEAWKALGDSSPSQAMQEYIAVVKKL-----------------------DPGWNPQIPEKKGKEANTGFGGPVISYHEETIREEDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEE--------------GRALLHWACDRGHKELVTVLLQHR---ADINCQDNEGQTALHYASACEFLDIVEL----------------LLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 282
5 -42.800[R] KOG0514 Ankyrin repeat protein  ali follow..  13  140....TENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSRESQHIP-------------TAEGASGSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDVVNIADSNGNTALHYSVSHAN----------------FPVVQQLLDSKVDKQNRAGYSPIMLTATQDDIETVLQLFRLGNINAKASQA--------------GQTALMLAVSHGRVDVVKALLACE---ADVNVQDDDGSTALMCACEHGHKEIAGLL---------------LAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRM.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 442
6 -42.700[OT] KOG0505 Myosin phosphatase, regulatory subunit  ali follow..  11  61VFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFL-------------VENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSE----GEVPSDLAEEPAMKDLLLEQVKKQGIDLEQS-------RKEEEQQMLQDARQ----------WLNS------------KIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYELNVQDYD--------------GWTPLHAAAHWGVKEACSILAEAL---CDMDIRNKLGQTPFDVADE-----------LVEHLELLQKKQNVLRSE---KETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQENKESSSSSSEEEEGEDEASESETEKEADKKPE........................................................................................................................................................................................................................................................................................................................................................................................................................................................... 385
7 -41.500[R] KOG0509 Ankyrin repeat and DHHC-type Zn-finger domain containing proteins  ali follow..  12  1................MEGPGLGSQCRNSHGPHPPGFGRYGICAHENKEL-------------ANAREALPLIEDSSNCDIVKATQYGIFERCKELVEAGYDVRQPDKE----NVSLLHWAAINNRLDLVRFYI-------SKGAVVDQLGGDLNSTPLHWAIRQGH----------------LPMVILLLGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVN--------------GQTPLMLSAHKVGPEPTGFLLKFN---PSLNVVDKHQNTPLHWAVAAGNVNAVDK----------------LLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLKTEAKMRANQKFRLWRWLQKCELFLLLMLSVITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLLSSVFWIFMTWFILFFPDLAGAP------------------FYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEKKVNIITLAE-----------TGSLDFRTFCTSCLIRKPLRSLHCHVCNCCVARYCLWTGRCIGFGNHHYYIFFLFFL........................................................................................................................................................................................................................................................... 478
8 -40.300[R] KOG0508 Ankyrin repeat protein  ali follow..  10  14.WIIHWEQQQTEMKLVFKNIPYKPAQTKIFQGVRLNFAGVKSPCETLQVLFQQLGE--------IPNTSQEVISVRGLPPHPCMALRESFLSTCYCEAFNPSSPPLSGDCHKQGLTQGLLLLLCGLVEPVGLVPVAPPGQLSTAG--GRRGDAAAHRRLLRPPLGALRWRDRGGCAAAVGADHLDVVRSLLGASVNRTTRTNSTPLRAACFEGLLEVVPYLVEHQANLEVANRH--------------GHTCLMISCYKGHREIARYLLEQG---AQVNWRSAKGNTALHNCAETSSLEILQLLLGTNIVEYLIQEQPGQEQVTFSPEVLNRESYQSCCPTSREAAVEALELLGSTYVDKKRDLLGALKHWRRAMELRHQRVEYLPKLEPPQLVLAYDEVNTTEELEALITDPDEMRMQALLIRER............................................................................................................................................................................................................................................................................................................................................................................................................................. 479
9 -36.600[R] KOG2384 Major histocompatibility complex protein BAT4, contains G-patch and ankyrin domains  ali follow..  12  2........................................................................NSQNELHPNWLALTTLPLQLKRFVRAGDPDFIAESPKAVKHQIDGLNGAEAREFYKEVLDAPTTCQPNLPSTHKTAQTRREP---------ERILVPFDKSKFFRLATSNKVEELSQMKEEDLNSRDSFGWTALMMAACEGATEAVSWLVQRGVQVETSDKS--------------GNTALKLAQRKGHLDVVHLLESLPIEETSEEDESVDGNNPFYCEICKRD----------------YKETPWPIHQTSTVHQFNLKALPKLHKFNISAKNRGLQLMVKQGWDQEH............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 257
10 -35.400[R] KOG1710 MYND Zn-finger and ankyrin repeat protein  ali follow..  12  1.....................................................................MTTTEEAPKSPLFEAIDKNDTEAALALLKTKEQAAQRDPS---------------------------------------------GMSVLAAAAYRGN----------------LTLVEKAIELKCDKTDGTLYTPLMFAALSGKQDVCRLLMDSGARMYLVNGI--------------GKTASELAAFVGHHECVAIINNH----ITIDVIEDLLRPKVNGKYEGAEEYPDELAVFIHS--------LCGSHEIHPVKIIFRFSKYPDSLKYKKKILYVIDRVFEKQLRCKESNEIMSLKLWLILFSMRETSKFV--ESNKEKSPEEASLQYAKLISTWQEGDETRRALDVMLRN.............................................................................................................................................................................................................................................................................................................................................................................................................................. 270
11 -34.700[R] COG0666 FOG: Ankyrin repeat  ali follow..  11  305.SNDHVINQSVAIIPALPKEQLLMLKGTVDEITPPLSPA-----TMNLLMAIGQNHQLKQLMIQLQKMPLTAYNSINLPGLYLAINYGNADIVETIFNSLSEPGYEGEAKDKNGFSGLFLAISRKDKNVVTSILNALPKDNEQVYKFLSAKNSTSSHVLYHVMANGDADMLKIVLLIRTCHLTKEQVLDLLKA----KDFYGCPGLYLAMQNGHSDIVKVILEALPSLAQEINISASDIVD-TAKSLARDTGLFMAMQRGHMNVINTIFNALPTLFNLLANNSNEYPGLFSAIQHKQQNVVEM-VYLALSDHARLFGFTAEDIMDFWQHKAPQKYSAFELACELGHRVIAELIFNTLNKMAESFGFTDNPRYIAEKNYMEALLKKASPHTVR............................................................................................................................................................................................................................................................................................................................................................................................................................................................... 728
12 -34.600[E] KOG1709 Guanidinoacetate methyltransferase and related proteins  ali follow..  7.LCLAAKSGDLKKVQTLIYSGADVTHFDNDGLTPLMHAAKIGNAEIVTAL-------------LESGAPWNALSPSNLSAGDFAMEAGHQETFDLLLKTGIQSELILGTI-----ARNQTKNEYSNQEYLQDRVSFSEDKLMDSESKGVMMA--WEKPLMEAHAKAICLNGGHILNV-------------FGMGLVDTAIQRYNPVKHTIIEAHPEVYKRMIESGWGEKEQDVLDKLDDNSFDGIFFDTYGEYYEDLREFHQHLPRLLKPDGVY------SYFNGFCGSNAFFHVVYCNLVTL---------------EIENLGFSTQLIPLPVKDCLGDEVWEGVKQKYWQL...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 314
13 -31.800[T] KOG4335 FERM domain-containing protein KRIT1  ali follow..  1.........................................................................................................................................................MGYSALEIKSKMLALEKADAPDYSKIQIPKQEKWQRSMSTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSD--------------HWAPIHYACWYGKVEATRILLEKGK--CNPNLLNGQLSSPLHFAAGGGHAEIVQI---------------LLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYEKVRIYRM................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 220
14 -31.700[R] KOG1595 CCCH-type Zn-finger protein  ali follow..  11  1................................................................................................................................................................................MCGAKSNLCSSKTLTFMRQKSEDGASATCLLEFAACDDLSSFKREIEENPSVEIDESGFWYRRVGSKKMGFEERTPLMVAAMYGSMEVLNYIIATGR--SDVNRVSDEKVTALHCAVSGCSVSI-------------VEIIKILLDASASPNCVDANGNKPVDLLAKDSRFVPNQSRKAVEVLLTGIHGSVMEEEEEELKSVVTKYPADASLPDINEGV............................................................................................................................................................................................................................................................................................................................................................................................................................................................ 209
15 -27.400[P] KOG3733 Mucolipidin and related proteins (TRML subfamily of transient receptor potential proteins)  ali follow..  15  409.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VMIVVNDALIIIGTVAKIS-FTLTSIFLGMGALLVYVGVLRYFGFFSQYNILMLTLKRSA-PNIMRFMTCAIVLYAGFLIAGWVIIGPY----------------------SMKFRTLAESSEALFSLLNGDDMFATFYTINIKVFGTVYIYLFVSLFIYVVLSLFIAIIMDAYEVVKDRYSDGLRAIEKRGCLR................................................................................................................................... 594
16 -26.600[T] KOG0195 Integrin-linked kinase  ali follow..  14  2............................................................................................................................................................................EDIFHWCREGNSIQVRLWLEHDNNLGDDHGFSPLHWVAKEGHAKLVETLLQRGSRVNATNMG--------------DDIPLHLAAAHGHRDVVQMLIKER---SDVNAVNEHGNTPLHYACFWGYDMICED----------------LLNAGAQVGIANKDGHTPLEKAKPSLAKRLQDLVEKSGREVKVISFKEQSWQGLKTRSRDATLSRFKGISMGDLDLHTKLSVTPSGETWRGRWQKNDVVAKILAVRQCTPRISRDFNEE----------FPKLRIFSHPNILPIIGACNSPPNLVTISQFMP------------------RSSLFSLLHGATGVVVDTSQAVSFALDV----------------------------ARGMAFLHSLERII---PTYHLNSHHVMI-TARINMGDA---------KFSFQEKGRIYQPAWMSPETLQRKQADRNWEACDMWSFAILIWEL-TTREVPFAEWSPM-----ECGMKIALEGLRVKIPPGTSTHMAKLISICMRPKFDMVVPILEK................................................................................................................................ 445
17 -23.500[R] KOG0522 Ankyrin repeat protein  ali follow..  13  1..............................................................................................................................................................................................MASSTIDVTKYGHSPVHHAVVTRDYAGLKKLLSALPKMRDPSEVQNEAASVARRDVVNRDTALHLAVKLGDETSAEMLMAAG---ADWSLQNEHGWSALQEAICGREERIAMI----------------IVRHYQPLAWAKWCRRLPRLVATMHRMRDFYMEIT..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 158
18 -21.100[R] KOG0511 Ankyrin repeat protein  ali follow..  2..................................................................................................................................................................................................ADKLMDKNFEELCYSCRTGDMDNVDRLISTGVNVNSVDK--------------FDNSPLFLASLCGHEAVVKLLLQRG---AVCDRDRYEGARCIYGALTDTIRDT---------------LLSYDISKAVDVKQPFATHISSMYNDEGFLKRDITFRVSNGKLFTAHKFLLCARSEILAEKMVNEWAKHEIVSLEVRPDI-------------------FDIFLKFLYLIPILHQIEPGQYEELIELSSKFDIELLPEFLDKARHTADPTEKSRLMSDYQYKFTEVARSQLLIFVNNCIFRSTVDLANSERRVFSLMNCPAYPDVQLMVKNRNGAIRIYPCHLAVLSRAEYFKVMFTNNFKEKVTYIK--QLTLPNCVAEIILRY--LYAVDVLLLADILLE----------------------------DRLKTIASTIITQSKEFIQQYNVDVLYLSWEIGVERL-----QFAAKFIAIHLQELYKDPEIKRAIMLSSQRISLRQETDTIELVDDIRYYLLRKYSFEPDDVELFENQDDLE-----YLKQVGYLEYRKDMGMLDN............................................................................. 504
19 -19.800[T] KOG2209 Oxysterol-binding protein  ali follow..  2...........................NTEAEQQLLHHARNGNAEEVRQLLETMARNEVIADI---NCKGRSKSNLGWTPLHLACYFGHRQVVQDLLKAGAEVNVLNDM----GDTPLHRAAFTGRKELVMLLLEYNA--------DTTIVNGSGQTAKEVT--------------------HAEEIRSMLEAVERTQQRKLEELLLAAAREGKTTELTALLNNPPDVNCSDQL--------------GNTPLHCAAYRAHKQCALKLLRSG---ADPNLKNKNDQKPLDLAQGAE---------------------KHILVGNKVIYKALKRYEGPLWKSSRFFGWRLFWVVLEHGVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTDSKKSLEKAQSCQQRLDREISNFLKMIKECDMAKEMLPSFLQKVEVVSEASRETCVALTDCLNLFTKQEGVRNFKLEQEQEKNKILSEALETLATEHHELEQSLV--RNDFSIWSILRKCIGMELSKITMPVIFLSFLQRLTEYMEHTYLI-MQCVAAFAVSAVASQWERTGKPFNPLLYELVRDD-------------GFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWG------SVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAME-DQASEEKKRLEEKQR 901
20 -19.000[R] KOG2505 Ankyrin repeat protein  ali follow..  244..................KQGGSQGAADNTKGNIHSAGSGLRRYNEQALI-------KDIQQVFKD------GKLLETCDLIFVRAIGSSNRSIFFSQPGALISPKDPK------RVFPFTTKRATHSELLRCYKELVTPKDSISIKAQEEERKRQAEIEKEIRQSRLQEEERKK----------------LAKYTEVIISNLKASNIEAFLEYLRSNDLSINFQFYPKNVHLH--------------TSTPLHYAVTQKNAKLVAKLLRNG---ADPAMLNGNGKTPFEISTGNKEVKDEFLIARHEL--------------------ESFFDWEAAKVGAPQSREQIQKQRQKAKTKLENQRRDKERQEELRRKEAMQKIEEQSKRDYDKLHGEGHSLGINNVRKVDELQSLSPEMRMRIEREKRAAAAMKRMQTK................................................................................................................................................................................................................................................................................................................................................................................................................. 600
21 -16.400[T] KOG0521 Putative GTPase activating proteins (GAPs)  ali follow..  16  642...................................................................................................................................................................................................PFSQLDANQLLYMASVVHNLPVMCMAFALGADKMWKNPQD------------RQRSFLHQAVISGSVMACEFLLLNG---AAIDAVDEMGYSALHISTAKGHIAQVYL----------------LLKHKAAYDLSSSDGKKALDIAVDQENADIVTLLRLTQLNDEIGPNDEYNGEDETYKNVMKDFSKLPASQTRVLRQRHDSNTLESQRSSLTNS........................................................................................................................................................................................................................................................................................................................................................................................................................................... 827
22 -15.200[T] KOG0818 GTPase-activating proteins of the GIT family  ali follow..  12  44.............................................................................................................................HISQVRHL--KHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPLHSSVRTGNLETCLRLLSLGAQANFFHPEK-------------GNTPLHVASKAGQILQAELLAVYG---ADPGTQDSSGKTPVDYARQGGHHELAER----------------LVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDLSELAKAAKKKLQ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 271
23 -11.200[T] KOG0705 GTPase-activating protein Centaurin gamma (contains Ras-like GTPase, PH and ankyrin repeat domains)  ali follow..  376........................KKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLE----------DDWPVELRKVMSSIGNDLANSIWEGSSQ-KSTREEKERWIRSKYEEKLF--GQQLLRATADEDLQTAILLLAHGSREEVNETCG----------EGDGCTALHLACRKGNVVLAQLLIWYG---VDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 663
24 -10.400[C] COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J)  ali follow..  13  7................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AAFFYLFAFVAVASAFMVISSRNPVHSVLFLILTFFNAAGLFMLTGAEFLAMILLVVY---VGAVM-VLFLFVVMML-----------------------DVDFAEMKEGALQYAPIGALVGLILAAELIIVLGGYTFATRSNTAALGDILYTDYLYYFQISGLILLVAMIGAIV--LTLRHKEGVKRQSIAAQVGRTPA............................................................................................................................... 192
25 -9.840[P] KOG3684 Ca2+-activated K+ channel proteins (intermediate/small conductance classes)  ali follow..  274...........................................................................................................................................................................................................................................................................................................................................................................................................................................RAPFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREAQLFVIDNGADDWRIAMTYERILYISLEMLVCAIH-TPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLTRFVMKTLMTIVLLVFSISLWIIAAWTVRAC------------------ERYHDQQDVTSNFLGAMWLISITF--LSIGYGDM-----VPHTYCGKGV-CLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSE--DLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGV 698
26 -9.430[P] KOG3713 Voltage-gated K+ channel KCNB/KCNC  ali follow..  11  168..................................................................................................................................................................................................................................................................................................................................................................................................................................VWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFS---------KLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVLRIMRIARIFKLARHSSGLQTLTYAL-FKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKS-------------------QSFWWAIITM--TTVGYGDI-----YPKTTLGKLN-AAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIPLLTEEKHHRTRLQSCK.................................................................... 494
27 -9.250[S] COG4291 Predicted membrane protein  ali follow..  90..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AIIAVTLLAVGVAVVSLFQALNHTGETVWTLLIAFASVIFGWLTIHTMTALHYAHLYWRPATVDGKPQHRGGMDFPATKEP-------CGYDFLYFAVVI--MTAQTSDVGVTTTAMRKVTLLIVSFFFNTVLVAAAVNAAVSLAG........................................................................................................................................................... 229

FFAS is supported by the NIH grant R01-GM087218-01
1 3 7 5 6 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Veeramalai M, Ye Y, Godzik A. TOPS++FATCAT: fast flexible structural alignment using constraints derived from TOPS+ Strings Model. BMC Bioinformatics. 2008 Aug 31;9(1):35