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Query: [I] KOG3729 Mitochondrial glycerol-3-phosphate acyltransferase GPAT, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLTTVLNFAQRVAEISLLGGIEIASVALIVYYIFAKTRAPVIIASLFPNLNLSYRTSYLSKINTIRSDLLVTLRSSNEPKTQNSVAHGIGTQNMLELTPHSGQKPFKKLFDWGVLFPYVAQVVRSEKFEYRQVTEIVHNDAVLKHAIKQAAEQTLREQRYAKNGHRLLTRSASGDQEAQEEEDEKRGISYQAILRKQEQRAISILKDMGSTLNNGLLAFTSWILYKLLPCFLSGVVTNTKQIEMLKTATERSPGTPLIFVPLHRSHLDYIMVTWILTNNDIRSPLVAAGNNLQIPVFGGLLRGLGAFFIKRKIDPVEGKKDVLYRAALHLYLTHALKQGHNVEFFIEGGRTRTGKPCMPKGGILSVIVNAFMDGSIPDALLVPVSVNYERLVDGNFVREQKGEKKIPESFGKAISGIWKALKSNYGLMRIDFNEPYSIRELVNSYNKIAREDGNIAKVYKPSARVLQHNQSTSSLYGTDVVCEEHRNLIESISRQVVFDCAAATSVMSTNALAFLLLTRFRNGAEEQILSEALDDLRNSLSGCKDIGFSGESSQIVAYACDLLGSGLVTRSRDENGRLVIKAVNSVESFIELAYYSNMLTPHFALSSILLTTFHSLLPETENKKEAAVSRKKLIDTALENCQIYRYEFILNKPTQVLENLLYQQLDDLLISGCVLTEKLHDDLPNGAEGRRLANVLAECLDEDGYEDVRDGEADEPKLLFASETPSQQRYICEVLAPFAWTYVTVAQSLQILHKNSMLESEFISFVINDLSSKVKRGSCIYAESISTDSVRNCLKLLEKWSVIEVCNQQGMRLISLNTLYEMSRESLNSIVKKIDAIVPKFNSGYFSVTPLast
1 -175.000[I] KOG3729 Mitochondrial glycerol-3-phosphate acyltransferase GPAT  ali  100  1MLTTVLNFAQRVAEISLLGGIEIASVALIVYYIFAKTRAPVIIASLFPNLNLSYRTSYLSKINTIRSDLLVTLRSSNEPKTQNSVAHGIGTQNMLELTPHSGQKPFKKLFDWGVLFPYVAQVVRSEKFEYRQVTEIVHNDAVLKHAIKQAAEQTLREQRYAKNGHRLLTRSASGDQEAQEEEDEKRGISYQAILRKQEQRAISILKDMGSTLNNGLLAFTSWILYKLLPCFLSGVVTNTKQIEMLKTATERSPGTPLIFVPLHRSHLDYIMVTWILTNNDIRSPLVAAGNNLQIPVFGGLLRGLGAFFIKRKIDPVEGKKDVLYRAALHLYLTHALKQGHNVEFFIEGGRTRTGKPCMPKGGILSVIVNAFMDGSIPDALLVPVSVNYERLVDGNFVREQKGEKKIPESFGKAISGIWKALKSNYGLMRIDFNEPYSIRELVNSYNKIAREDGNIAKVYKPSARVLQHNQSTSSLYGTDVVCEEHRNLIESISRQVVFDCAAATSVMSTNALAFLLLTRFRNGAEEQILSEALDDLRNSLSGCKDIGFSGESSQIVAYACDLLGSGLVTRSRDENGRLVIKAVNSVESFIELAYYSNMLTPHFALSSILLTTFHSLLPETENKKEAAVSRKKLIDTALENCQIYRYEFILNKPTQVLENLLYQQLDDLLISGCVLTEKLHDDLPNGAEGRRLANVLAECLDEDGYEDVRDGEADEPKLLFASETPSQQRYICEVLAPFAWTYVTVAQSLQILHKNSMLESEFISFVINDLSSKVKRGSCIYAESISTDSVRNCLKLLEKWSVIEVCNQQGMRLISLNTLYEMSRESLNSIVKKIDAIVPKFNSGYFSVTP 850
2 -129.000[I] COG2937 Glycerol-3-phosphate O-acyltransferase  ali follow..  16  59.QCLAHDLPDPLEPLEIDGALLPRYVFIHGG---PRVFTYYTPKEESVKLFHDYLDLHRSNPALDVQMVPVSVMFGRAPGREKGEDN------------PPLRMLNGVQKFFAISWLGRDSFVRSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQKLLASKAIARAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVR----QLAHDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKG-----NKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLKGLSKLR-NLGQGYVNFGEPMPLMTYLNQHVPEWRESIDPIE---------------------AIRPAWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLDCYLDLMRNVPYSTDSTVPAASAGELIAHALQMNKFEVEKDTIGDII--ILPREQAVLMTYYRNNIAHMLIMPSLMAAIITQ---------HRRISRDALQQHVEALYPMLKAELFLRWEREELASVIDALASEMQRQGLITLQDD-------------------------------------ELHINPTHSRTLQLLAAGARETLQRYAITFWLLSANP--SINRSTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPAETMKIYQMLADLIT-SDVRLTIESATQG.......... 805
3 -92.300[I] KOG3730 Acyl-CoA:dihydroxyactetone-phosphate acyltransferase DHAPAT  ali follow..  16  2......................................................................................................................TSASQTGRQINYPEYENFLELKNKGGPFKFVTATKNFPVGSKVGTAPKTRSLASVLESPRVKSVISEETLRRKCSPDLVRKEAEEILDEMSHTFNLYNVRSFGYAVCKAMEKLYDGIYVNEKKLLEIRER---SKKDCVIFMPSHKTYFDFLLLSLICFQYDIQLPAIAAGQDFSMKFMAGVLRRSGAFFMRRSFGT-----DQLYWAVFSEYVQTHVNNDRTVEFFVEATRSRVGKSLHPKYGMLQMVLEPYLRGSVYDIVIVPVSMNYDKILEEKLYAYELLGFPKPKESTGALLKAREMLKITHGSCFLTFGEPISVRDHFGVSLHRNTFVCQPDSQ--------------------FVLDAQAKLEIKSWLHFLMKREFVTVPGELPQLFDATLDILRASEILQFTDDNKIEILDEKNAEVLSKLVLPYFYNFEIAFNVFSEKKPMVSSLSEM-----VGTVQKNISEAYQDRLPNIRLSFLSTEPIKNAFAALTDFGVFENSNRPNFGKLHQIKNRLQRFTQSENHLAK...................................................................................................................................................................................................... 512
4 -19.200[I] KOG2848 1-acyl-sn-glycerol-3-phosphate acyltransferase  ali follow..  16  88...................................................................................................................................................................................................................................................KIENEEILRKHKSAVLVVNHQSELDILAIGRTF-----NYSVIAKKSLRYVPILGWFMILSDVVFIDRSRRSDAIQL-------FAKAARRMRKENISIWVFAEGTRSYSLKLLPLKKGAFHLAVQA-------QVPIIPIAITYGHLFHPPTKV-------------------------NKGEALIKVLDPIPTEGKTAEDVND.................................................................................................................................................................................................................................................................................................................................................................................................................. 254
5 -17.200[I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase  ali follow..  13  50.........................................................................................................................................................................................................................RRIIGTSWRLFVAYLKWSGVLEVSFKGVEKL----NRPGQLILANHPSLLDVVLLVGHV-----EMNCIVKKDLQHNPAMSSQIKGAGYIPNEES------------EAMLET-VKAVFDSGQSLLVFPEGTRTGWDGRVKMHRGAVSLGLRY-------AEVITPVCINPPNFKKGQPWYR---------------------IPPKRIRYEITVGDDILPQDWLAE...................................................................................................................................................................................................................................................................................................................................................................................................................... 229
6 -13.300[I] KOG2898 Predicted phosphate acyltransferase, contains PlsC domain  ali follow..  14  132...............................................................................................................................................................................................................................IERVLVEMICSFFVASWTGVVKYHGPRPSIRPKQVYVANHTSMIDFIVLEQMTAFAVI----MQKHPGWVGLLQSTILESVGCIWFNRS----EAKDREIVAKKLRDHVQG--ADSNPLLIFPEGTCVNNNYTVMFKKGAFEL-----------DCTVCPIAIKYNKIFVDAFWN----------RKQSFTMHLLQLMTSWAVVCEVWYLEPQTIRPFAERVRDMISLRAGLKKVPWDGYLKYSRPSPKHSERKYVVLSRDSTVIILSI...................................................................................................................................................................................................................................................................................................................................................................... 376
7 -13.300[I] KOG4666 Predicted phosphate acyltransferase, contains PlsC domain  ali follow..  17  178......................................................................................................................................................................................................................................................EAATEEPERPGAIVSNHVSYLDILYHMSA-----SFPSFVAKRSVGKLPLVGLISKCLGCVYVQRE---AKSPDFKGVSGTVNERVREANKSAPTIMLFPEGTTTNGDYLLTFKTGAFL-----------AGTPVLPVILKYPYERFSVAWDTI-----------SGARHILFLLCQVVNHLEVIRLPVYYPSQ.......................................................................................................................................................................................................................................................................................................................................................................................................................... 343
8 -11.700[S] COG2121 Uncharacterized protein conserved in bacteria  ali follow..  14  8....................................................................................................................................................................................................................KNIVLKVVPRLAFGVLWLLHKTCKNRYFLAQDLK-------EKPFIVSCWHGE---LGMIGFAYLRLQKPSVYVIASQHFDGSIAAGLFESFGFKNIRGS--SKKGGVKVLIEGL------KRLKEGCDVAITPDGPK---GPRHSIADGVIALAQKS-------GVGISACRVTWDQF----------------------------EIPKPFSEVRYYMLESVIIPKEWELSKAKEYLKTRMDSVGFEESQRGLGA............................................................................................................................................................................................................................................................................................................................................................................................. 217
9 -9.960[I] KOG1505 Lysophosphatidic acid acyltransferase LPAAT and related acyltransferases  ali follow..  15  37...........................................................................................................................................................................................................LLWPINKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKT--------VATSLQHLRDYPEKYFFLIEGTRRAKGHHLLPRTKGFAITVRSLRNV-----AVYDCTLNFRNNENPTLLGVLNGKKYH............................................................................................................................................................................................................................................................................................................................................................................................................................................................ 250
10 -9.960[I] KOG4321 Predicted phosphate acyltransferases  ali follow..  10  96.........................................................................................................................................................................................................................VAIASFWDGVGNVWHG---------YELRGIENVPDEGSALFIYYHGCLLDYYLISKLVIHKNRSLHCVGDKFIFKIPGWRPLCKLFSIT------------------SGTVEECTEELKEGNLLCIAPGGVRNVYDILWGKRLGFAKVIIGS-------KTPVIPMFT----------------NCRESFRTPEWGRSFFRWIYEKTKKMITHLGKPIEIRMMIKEHQRLPGSVWRGIAQRWSSTSSKKKNSDEPEQAELLQRNGAGTTSPTSDSEDIVVLRRDRSGVEDDDAFNLFFWEVLIENIQRKLLQYSKKKILEK....................................................................................................................................................................................................................................................................................................................... 413
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 2 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.