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Query: [I] KOG3845 MLN, STAR and related lipid-binding proteins, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSGRQPLISPGSQRIGVSKDRKRFIVITFFDTSITILLWLLCTVTRDDDWDKVFFNEINIFNPKFIRISLFDIVLLAVLRMLILGVVYGICLVKQWYTVAFTTLASSAYILMKVLFYFNHSSSAVPPLLLIITSFTLCWSEFYLMPFQILPRERRYARRELDGIENPEFSTDDEARSNNRHRRGRRQQNSGNQSEAPTAVPSRVSSGVFIASDYDEFRSAAEFSSDEEARSRLLVPPDTKRLFEITLRECLDQVEELMRDSRLGGWKTLRSANPTVLQGPDNYFLVIEGKMIAHLDNATDLYYSVSAPAMRGYISSRDFLDLRKIKLDSSADVYTGYFVSVESNLCPNNGNPKIVRGHNFPSMIRTLKDEAGVTYFEWLMKTDLKGGLPRRLVHSGMVNYFSEHVKRMNEFAETHYHCPPLast
1 -113.000[I] KOG3845 MLN, STAR and related lipid-binding proteins  ali  100  1MSGRQPLISPGSQRIGVSKDRKRFIVITFFDTSITILLWLLCTVTRDDDWDKVFFNEINIFNPKFIRISLFDIVLLAVLRMLILGVVYGICLVKQWYTVAFTTLASSAYILMKVLFYFNHSSSAVPPLLLIITSFTLCWSEFYLMPFQILPRERRYARRELDGIENPEFSTDDEARSNNRHRRGRRQQNSGNQSEAPTAVPSRVSSGVFIASDYDEFRSAAEFSSDEEARSRLLVPPDTKRLFEITLRECLDQVEELMRDSRLGGWKTLRSANPTVLQGPDNYFLVIEGKMIAHLDNATDLYYSVSAPAMRGYISSRDFLDLRKIKLDSSADVYTGYFVSVESNLCPNNGNPKIVRGHNFPSMIRTLKDEAGVTYFEWLMKTDLKGGLPRRLVHSGMVNYFSEHVKRMNEFAETHYHCPP 420
2 -29.800[I] KOG2761 START domain-containing proteins involved in steroidogenesis/phosphatidylcholine transfer  ali follow..  13  5.........................................................MDFFNKPSVTETFVDVLLCAV-----------------WVTV--------------------------MIGLLIGWSWRPRWTSLVYLGFRSKLRFLCTVARRIWLAFTALSAFSVCSTSNKSSVNNGSSKPVEEEAFSRASDKVTEKEKDVVTEKDLEHLLHLLEAGNASFEWQSMMDKSTPNMSYQAWRHEPEIVYRSRTVFEDVTPDIVRDFFWDDEFRPKWDTMLAYFKTLEEDPKTTTIVHWIKK--FPFFCSDREYIIGRRIW--ESGRKYYAVTKGVPYKALSKRDK--PRRVELYFSSWIINAGDGQMTACEVSLVHYEDMGIPKDVAKLGVRHGMWGAVKKLNSGLRAYQSARK 334
3 -24.700[TV] KOG1739 Serine/threonine protein kinase GPBP  ali follow..  11  339.......................................................................................................................................................QSQSEKVRLHWPTSLPSGDAFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIIYQTHKRVWP--ASQRDVLYLSVIRKENDPETWIVCNFSVDHDSAPLNNR--CVRAKINVAMICQTSRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKP 621
4 -17.900[T] KOG2200 Tumour suppressor protein p122-RhoGAP/DLC1  ali follow..  12  576...QVGLFRKSGVKSRIHALRQMN---VNYE--VADMV-------------KQFFRDL------LFTNKLSETFLHIY-RLQAVQAAILLLADENR-----EVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLF---ATGKPDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQGLQKEAKEKFKGWVTCSSTDNTDLFKKVGDGNPLKLWKASVEVEAPPSVVLNRV---LRERHLWDEDFVQWKVVETLDRQTEIYQYVLNSMAP---PSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQLLGG---VRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWY-SKGFGHLCAAEVARIRNSFQPLIAEGP 991
5 -10.700[S] KOG1032 Uncharacterized conserved protein, contains GRAM domain  ali follow..  9  194.............EQRNKDFHETF-LLDDFELLYQGKLYILC-----------FNSNVLGWIAKVL-IAFEDVTFMEKTSAAGLF------------AISIETKMG------KTLFNGFISRDAAFGLMK----------EVW----RTLLQKDMASENINTKAEKSGNGKEIDDAINSIDEENNDKDANDNDTNENDDENISTNETTPNSTSSSPDKEKEKAYKLRADSSYQYDGPIYHHSTSFPAEPMANNEFVLKELPFDCAPGILFEIMFNSEQNEFLLDFLRGQEGSQITTLKREYSYEK---ALHFPAGPKS-CYVAEVIKRKDPDTYYEVISSIRTPNVP--GGSFSTKTR-----YLIRWNDEITCLLRVSFWVEIKGMVENGCKN-GQLEAAQLMERILSKFIKNNVEE.. 584
6 -10.300[R] KOG3656 FOG: 7 transmembrane receptor  ali follow..  9  96IAGNCLVVISVCFVKKLRQPSNYLIVLALADLSVAVAVWIF----------HFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAAT.............................................................................................................................................................................................................. 327
7 -9.790[S] COG4331 Predicted membrane protein  ali follow..  11  1MLKMKNRFSSKNLFGE-KNVHAVFELSLLLKIIAGVLTYFVTPQFLLNTLHRITQVSFIESRGDIIANYLFAASYLFIHGAIKLWIIIGLWRKKLG----VAVAVFSLFIVYQL--YRYTFTHSLLLILITILDVFVIAL---LLEYRRLRHGEKTCS...................................................................................................................................................................................................................................................................... 172
8 -9.720[S] COG3308 Predicted membrane protein  ali follow..  16  1MARKNKPLPEVAWLQPRLALSRAISLGSFVGLVLLILIRDLIYADAHGA------------------ASWVPWLVLAFKLLPLLVVAPGLLM-GSARGHAWACYVVNLYFILGVLAAFDPTQRGWAEVLLSVTLFCAA-----LLYTRWRFQYDRRVAGER................................................................................................................................................................................................................................................................... 139
9 -9.580[T] KOG4220 Muscarinic acetylcholine receptor  ali follow..  10  45IVGNVLVMISFKVNSQLKTVNNYYLLLACADLIIGIFSWAL----------SLACDLWLALDYVASNASVMNLLVISFDRYFSITLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAEKRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAK............................................................................................................................................................................................... 296
10 -9.500[S] COG3152 Predicted membrane protein  ali follow..  12  1MSLQTLLFS----QGRIG--RQAFWLWNICYYAMIAGFAMGSNLLFPD--------VAHLILPVFLLVVLVPDLAITAKRW---------RDKSSWWLLLNVPLVIGRMTIPAGELAVNTQPGMLETLISFVALLCGAWILVECGFLSGTDGSNR......................................................................................................................................................................................................................................................................... 135
11 -9.440[R] COG5198 Protein tyrosine phosphatase-like protein (contains Pro instead of catalytic Arg)  ali follow..  11  61FHSIFGLVSSSPLTTIIQVASRLYLVWGVCYYLSMIIAWSI--------------TEIIRYAFYAFNLNGDIPAFLTWLRYNTFLILY---------PIGAGSEFLLVLKSRIAAQYVWSLNKLLWPILMSIPGLYIMYTHMLAQRRKISKRAAARRT...................................................................................................................................................................................................................................................................... 208
12 -9.200[S] KOG3455 Predicted membrane protein  ali follow..  15  9.....................RSWLVMVSIIAMGNTLQSFRDHTFLYEKLYTGKPNLVNGLQARTFGI----TLLSSVIR---CLCAIDIHNKTLYHITLWTFLLALGHFLSELFVYGTAAPTIGVLAPLMVASFSILGMLVGLRYLEVEPVSRQKKRN..................................................................................................................................................................................................................................................................... 140
13 -9.000[R] KOG3187 Protein tyrosine phosphatase-like protein PTPLA (contains Pro instead of catalytic Arg)  ali follow..  7  58IHAIVGLVRSPVGTTAMQVTSRVVLVWPILHVPLLLVAWSV--------------TEVIRYSFYALSVLKQPI-FLLYLRYTLFYVLY---------PMGVSGELLTLFASLNEV----NRLNMGISFWWVLIIAALSYIPGFPQLYFYMIGQRKKILGGGSKKKQLIATNQNSTLFINYSPKTKRQWKCFSAEFVDILCSPFGIFVIVIREES.............................................................................................................................................................................................................. 266
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 2 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.