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Query: [W] KOG3848 Extracellular protein TEM7, contains PSI domain (tumor endothelial marker in humans), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MARFPKADLAAAGVMLLCHFFTDQFQFADGKPGDQILDWQYGVTQAFPHTEEEVEVDSHAYSHRWKRNLDFLKAVDTNRASVGQDSPEPRSFTDLLLDDGQDNNTQIEEDTDHNYYISRIYGPSDSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLREITVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEESKEKMCENTEPVETSSRTTTTIGATTTQFRVLTTTRRAVTSQFPTSLPTEDDTKIALHLKDNGASTDDSAAEKKGGTLHAGLIVGILILVLIVATAILVTVYMYHHPTSAASIFFIERRPSRWPAMKFRRGSGHPAYAEVEPVGEKEGFIVSEQCLast
1 -157.000[W] KOG3848 Extracellular protein TEM7, contains PSI domain (tumor endothelial marker in humans)  ali  100  1MARFPKADLAAAGVMLLCHFFTDQFQFADGKPGDQILDWQYGVTQAFPHTEEEVEVDSHAYSHRWKRNLDFLKAVDTNRASVGQDSPEPRSFTDLLLDDGQDNNTQIEEDTDHNYYISRIYGPSDSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLREITVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEESKEKMCENTEPVETSSRTTTTIGATTTQFRVLTTTRRAVTSQFPTSLPTEDDTKIALHLKDNGASTDDSAAEKKGGTLHAGLIVGILILVLIVATAILVTVYMYHHPTSAASIFFIERRPSRWPAMKFRRGSGHPAYAEVEPVGEKEGFIVSEQC 529
2 -8.130[S] KOG4808 Uncharacterized conserved protein  ali follow..  10  23.........................................................................................................................................................................................................................................................................................................................................................................................................PAARVRWESSFSRTVVAPSAVAGKRPPEPTTPWQEDPEPEDENLYEKNPDSHGYDKDPVLDVWNMRLVFFFGVSIILVLGSTFVAYLPYRCTGCPRAWDGMKEW--------SRREAERLVK---EANGLPIMES. 149
3 -7.330[R] KOG4299 PHD Zn-finger protein  ali follow..  13  262.........................................................................................................................................................................................................................................................................................................................................NNDYCSACHGPGNFLCCETCPNS-TCIDEKNLPDDAWYCNECKHHSLYNELDEQEELESNVKEEGTMVDVWMQLCTYIDSHNPIQFHLPHSISSFIETDVLKHLKSSRRSNGEERDPLLLKSKSGTPILCFRCILACDYCNSYWHPDCLNPPLATL--------PSKW-RVGLPRGFKNKGNIVIDENEDEPSVQTIQL. 503
4 -7.330[J] KOG4600 Mitochondrial ribosomal protein MRP7 (L2)  ali follow..  10  19....................................................................................................................................................................................................................................................................................................................................................................................................SLSSTSSFLRGDLSFSPKTSFTVTLPLENLQAPIPLTIESAHKKGAGSTKNGRDSPGQRLGVKIYGDQVA-------------------------KPGAIIVRQRGTKFAGKNVGIGKDHTIFSLID------GLVKFEK. 128
5 -7.280[S] KOG4781 Uncharacterized conserved protein  ali follow..  6  153.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................HPGLIATCMVLAICSAVTANLKLSNPTKAYTNHFYILRSHLEW---TKGRKAQTHGTAYMLDNEDPSKSTCVAI.. 233
6 -7.210[K] KOG2857 Predicted MYND Zn-finger protein/hormone receptor interactor  ali follow..  8  9.............................................................................................................................................................................................................................................................................................................................................CEICEKVVSKYKCPSCL-VPYCS-------------GCFKIHKVCNLI----NNAETPCAKPSDPSSTEEKPVVQCEPWFESCSGFVAASPAKEVPVKRPEEANDVVEKTQQKASASSSE--------------------IREALKDEPLQKLIYSIDSSSNPLQELEAMGIEAFREFTDISKSNDEQGISTMDI. 172
7 -7.140[S] KOG2257 N-acetylglucosaminyltransferase complex, subunit PIG-P, required for phosphatidylinositol biosynthesis  ali follow..  15  3...........................................................................................................................................................................................................................................................................................................................................................................................................................................................SLNQEVHGPKTSEVYGFVGSISIVVATVIFLIWGY--PDKFLESIGIYYYPSKWAMA............................. 59
8 -6.830[O] KOG3206 Alpha-tubulin folding cofactor B  ali follow..  13  89...................................................................................................................................................................................................................................................................................................................................................................................................DHSGARLGEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQQEAEAAQRLAEEKAQASSIPVGSRCEVRAAG-GTVMYV--------GL--TDFKPGYWIGVRY------------EPLGKNDGSVNGKEC 216
9 -6.660[C] KOG3469 Cytochrome c oxidase, subunit VIa/COX13  ali follow..  10  2....................................................................................................................................................................................................................................................................................................................................................................................................................................SAILNHAIRRQFGASAARNMSGTAAVAGEHSGGYKVWKRLSFFVAVPAVGLCFVKYDYLR---------RREKRFPW-------GEGQKSHVNALPDGYEH........ 109
10 -6.660[J] KOG3419 Mitochondrial/chloroplast ribosomal protein S16  ali follow..  16  1........................................................................................................................................................................................................................................................................................................................................................................................................................................................................MAFTFVFLGSSIGTTNWLLSGYGNPH--------QRRPSKW----------------YNPAGLREGVVKLDVC 71
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.