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Query: [G] KOG3893 Mannosyltransferase, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MITFLEVFVYFYFFPLLVFITLQYPRWTFNKWKALLPVSAYISFYFIIISSFSTHLNILYFNLSKSMVSFAQVPLEEYLNLLGHSLLTSIIYVMLKRRFYEQSVYNAKNGMLVYVNAIFAVVGIYCSVVHKSILQIGVTLTFICPMLSFLLCFRIIISQKAALVSIGISTLYYCFVQFMEVKSALISYDRSLFKFYPIDLFVLLLSQSFICIIAFGVSDFINFQKEERNFRGKSNSAFYNDFIQSFKSEDLIQEYESSLLLEPSLRLRISYLALFLKNTLQFGYIRKKENVNLNLVKTPKYDDLTKMNLSSSTANTLIKGIQSYNFQNYEKAYSLLAAGVTNSLLEWTNTSVSDKEYLRIQCFIQSCLQYRLTQDEKYLIDLDVKVCSLFNTSAREALIHYAKAMKLLSKYNSRENMITKLRESSLYLLYAPTDAFLLLLLGLLMRLVLLNYGIWHDRRSALKFTDIDYFVFSDASKYVSIGMSPYMRDTYRYTPMLAILLLPTQYGFPSWGKYLFSISDLIAGWLMIKLLSRRISYKRSLIYSSFWILNPFVAIISTRGNCEAILGILSIALLYLIEKKSVWLASLILGFSVHFKIYPFMYGIAFLVYFSKPKKGSTFMEKFLSLLSINQLKIVVGSLFMFTICNLLMYYLYGSPFLEHTYLYHFGRTDHRHNFSLHHLNLYYESSFGAKASSLFAFLPQLSLCMLIPLVFGKKNLPGTLFAQTFAFVTFNKVCTSQYFMWYLVFLPLVLPNSKLLSKKGLICLSLWIIGQLLWLISAYNLEMLGKSVFIPLWLSGLLFFFFNVYELKIILDSLLast
1 -220.000[G] KOG3893 Mannosyltransferase  ali  100  1MITFLEVFVYFYFFPLLVFITLQYPRWTFNKWKALLPVSAYISFYFIIISSFSTHLNILYFNLSKSMVSFAQVPLEEYLNLLGHSLLTSIIYVMLKRRFYEQSVYNAKNGMLVYVNAIFAVVGIYCSVVHKSILQIGVTLTFICPMLSFLLCFRIIISQKAALVSIGISTLYYCFVQFMEVKSALISYDRSLFKFYPIDLFVLLLSQSFICIIAFGVSDFINFQKEERNFRGKSNSAFYNDFIQSFKSEDLIQEYESSLLLEPSLRLRISYLALFLKNTLQFGYIRKKENVNLNLVKTPKYDDLTKMNLSSSTANTLIKGIQSYNFQNYEKAYSLLAAGVTNSLLEWTNTSVSDKEYLRIQCFIQSCLQYRLTQDEKYLIDLDVKVCSLFNTSAREALIHYAKAMKLLSKYNSRENMITKLRESSLYLLYAPTDAFLLLLLGLLMRLVLLNYGIWHDRRSALKFTDIDYFVFSDASKYVSIGMSPYMRDTYRYTPMLAILLLPTQYGFPSWGKYLFSISDLIAGWLMIKLLSRRISYKRSLIYSSFWILNPFVAIISTRGNCEAILGILSIALLYLIEKKSVWLASLILGFSVHFKIYPFMYGIAFLVYFSKPKKGSTFMEKFLSLLSINQLKIVVGSLFMFTICNLLMYYLYGSPFLEHTYLYHFGRTDHRHNFSLHHLNLYYESSFGAKASSLFAFLPQLSLCMLIPLVFGKKNLPGTLFAQTFAFVTFNKVCTSQYFMWYLVFLPLVLPNSKLLSKKGLICLSLWIIGQLLWLISAYNLEMLGKSVFIPLWLSGLLFFFFNVYELKIILDSL 815
2 -66.500[R] KOG2552 Major facilitator superfamily permease - Cdc91p  ali follow..  14  3..................................................................................................................................................................................................................................................................................................................................................................................................................................EEKKDDGVMAEEKPYMFWIWTLASTIFRLFLIFSPINLSSRPEVSTPHTSLRRLAEGYWLKQSSLSPYAGSMYHGSPLLLSILGPLTVQSDSKGNRVIICADLLSALLLRAIGQKLQKSYCGDIAALVYLWNPFTILSCVGLSTSPIENLAVIVSLYGAVTRRVPLAAFGLIMATHLSLYSAPLVFPLIFLLGYGLPTTQLPFSWRTVLHFVFWVLVWSSYVLVLCSLSLKQYGGLEEMFKRTYGFILRIEDLSPNIGVFWYFFAEAFEFSRNYLLIIFNLYILLTSIPSLMFRLKHRPCFLAFAYLAFTSILKSYPSVGDAALYLSLWALFVNELTD-MEYSFFIFCGYIGFSLLSPVMHNFWIWRGTGNANFYFGNAMGYACFQFMFVEKSVNAM 457
3 -35.800[S] COG5650 Predicted integral membrane protein  ali follow..  13  46.................................................................................................................................................................................................................................................................................................................................................................................................................................................TPLRVLITTSLVFLAMGFLTK-SRQYTSACYNDIVPLYGGRGIDYAFSWQEGDLTRYMEYPVLGGIFQWICGIITRFLYPLYFIVTALALAFFWVLVIRMMVELTGNRVWDTVLVAASPLVAVHAFTNWDTPAIAAVIGAMLAVKRGNPLVAGVLIGAGTAFKLWPLYLLGAYLVLAVKNKNLKPFITMAAAAAVTWLVVNVPVMIAYPKAWNEFLRLNRERGAEWTTIYQVID----------RNLPINLNDPVLLNVLSFGLFGASCVAILILGLKVQRPRVAELAFLIVAAFLLFNKVWSPQYSLWLVPLAVLAFPQWKVLFPWMVTDAMVWPI------LMWHMLGTDNKGLPHEMLLIVISRDAFIVVMIVGVIRQM 451
4 -16.200[O] COG4346 Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase  ali follow..  6  169..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TEHPFLGKDIIALGMLIEDK--RIPGIIEHALIVIIVTLVAYKITKSYLASSIAATFALDPLLFATGIVAMLDIHVAFFIALFMLFLALDRIRLSGIALGLAAATKLSGAFAFPILWFKILKEKDLKEYLISGL-------VLPMVSFLIPEITIIKAIGFIPWLEEFIASFSWHLSFKGEHPSEAPFWFHFDPDVYAVTDPILMISMIVFVFAVPYVSLRRKGLSFWSIIAFFALQYILGGKTQFIFYATPLIPPGAVAL................................................................ 440
5 -12.400[G] KOG2762 Mannosyltransferase  ali follow..  13  49....................................................................................................................................................................................................................................................................................................................................................................................................................................................LLILFESMLCKIII----------KVAYTEIDYKAYMEQIEMIQDGMLDYSQVSGGTGPLVVLIYKMMYWLTEERGQVFFRYLYLLTLALQMACYYLLHLSKRLHSIYVLRLFNDCFTTLFMVVTVLGAIVASRCHQRPKLKKSLALVISATYSMAVSIKMNALLYFPAMMISLFILNDAN----------VILTLLDLVAMIAWQVAVAVPFLRSFPQQYLHCAFNF---GRKFMYQWSINWQMMDEEAFNDKRFHLALLISHLIALTTLFVTRYPRKTIPFVLIASNFIGVLFSRSLHYQFLSWYHWTLPILIFWSGMPF---FVGPIWYVLHEWCW------------NSYPPNSQASTLLLALNTVLLLLLALT. 434
6 -11.700[S] COG5542 Predicted integral membrane protein  ali follow..  8  7.........................................................................................................................................................................................................................................................................................................................................................................................................................AMKNAEKKSNSYLAIRMTRSGYNYFKGICVCTFLLSTILYLGIAVIMSHLCVFDDTAFISWIRWDAIYFVDMAVNGSLEQEWAFSSLWPKIISFLAFRSKIVSCFASIFFHAIACYALYLLTKSISNQKMTAYTVIFYCFSPSGIYMSV---TESLFAAFSFLGLLLFIKKQQYPAAFLWSLATLIRSNGIFWCIFFGMPAIGTLKISLERLQLTFMQVSQLVGYGTKCLIILVPFFYNQYLGFKLFCPGVAWCNKSLPLIYPAVQEKYWNVGFLRYWTLNNIPNFLFALLSIIPILFALFYSISGSTLHSFRSIKSHLV----------LSALYLYIGCFHMHTQVLNRMSSAL-------PLLYWSMAHATLYAKSRNLKAFGHCILFVWIVYTVIQAGLYGS. 421
7 -11.600[O] COG4745 Predicted membrane-bound mannosyltransferase  ali follow..  12  2....................................................................................................................................................................................................................................................................................................................................................................................................................................RRSRDDSSPRVAAAVVAVTAAALLARLWALGWRVAHQD--EARVADWTLQYMDLGA---------WQYRPIIHGPFLPHVNGVVFDVFDFTMRLVVAVVGGLLPLTAW-LYRTRLSDVEVGALAVLLAANPVVLYYSRFMRNDLLLAGFMFTAVGLFVRRYLYASAVPFALAFTTKENSLLYPLCWLGALA............................................................................................................................................................................................................ 190
8 -11.400[M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family  ali follow..  10  1............................................................................................................................................................................................................................................................................................................................................................................................................................................MKSVRYLIGLFAFIACYYLLPISTRLLWQP--ETRYAEISREMLASGDWIVPHLGLRY----FEKPIAGYWINSIGQWLFNFGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLATVIYLSLFIVYAIGTAVLDPFIAFWLVAGMCSFWLA-FLLLGITCGMGVMTK--FLALAVPVLSVLPWVATQKRWKDLF------IYGWLAVISCVLTVLPWGLAIAQREPNFWHYFFWVEFALDDAQHRAPFWYYVPVIIAG----SLPWLGLLPGALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLM................................................................ 327
9 -11.000[GE] KOG2575 Glucosyltransferase - Alg6p  ali follow..  14  41.................................................................................................................................................................................................................................................................................................................................................................................................................................................SFLCISLFALLIRSAVTMYPYSGAGIPPKFG---DFEAQRHWMEITTN----YRNGTLDYPPLTAYQSYIHGIFLRLLMRWTVLSSDAFIFFPAALFFRTRGGKSEVAWHIAMILLNPCLILIHGHFQYNCISLGLTVGAIAAVLCESEVLTCVLFSLALSHKQMSAYFAPAFFSHLLGKCLRRKSPILSVIKLGIAVIVTFVIFWWPYVHSLDDFLMVLSRLAPFERGIYEDYVANFWCTTSILIKWKNLFTTQSLKSISLAATILASLSMVQQILSPSNEGFLYGLLNSSMAFYLFSQVHEKSILMPFLSATLLALKLPDHFSH--LTYYALFSMFPLL......................................... 417
10 -10.900[R] KOG2647 Predicted Dolichyl-phosphate-mannose-protein mannosyltransferase  ali follow..  10  3.......................................................................................................................................................................................................................................................................................................................................................................................................................................KALESNSKSRKETILIKYAIFSRLLVLFLTILWRSLLQPYDTSAALNP--DSVYFLRITECGYEEQTYAFLPLLPFFISLLSRTVFLSGFTVSNLAFIFAAIYLFRVSVIIKDTEASFRASIIFCFNPASIFYSS---SESLYALFSIGGVYHLLSGTSNVGVLWFALSGCARSNGILNAGYICFQTMHRAYEALYQKRRAYLAMQVFIAGFLRCICICLPFVAFQAYGY--GRIPLLYNFIQKILVSDRGVGFLKYFQFKQLPNF------LLASPILSLAVCSIMSYMKSRPELFISLPEKSGYLSADVFPFIVHLSFMVTTAFFIMHVQVATRFLSASPPLY------WFASSLIGSPKHSKWGYLIWSYCAAYILLGTLLFSNFY... 489
11 -10.200[O] KOG3359 Dolichyl-phosphate-mannose:protein O-mannosyl transferase  ali follow..  9  1...............................................................................................................................................................................................................................................................................................................................................................................MSSSSSTGYSKNNAAHIKQENTLRQRESSSISVSEELSSADERDAEDFSKEKPAAQSSLLRLESVVMPVIFTALALFTRMYKIGINN------HVVWDEAHFGKF----------GSYYLRHEFYHPPLGKMLVGLSGYLAGYNGSWDFASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVFENSYSTLGRFILLDSMLLFFTVASFFSFVMFHLLITGISLGCTISVKMVGLFIITMVGIYTVIDADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDL................................................................................................................................................................... 310
12 -10.000[O] KOG2292 Oligosaccharyltransferase, STT3 subunit  ali follow..  11  24..................................................................................................................................................................................................................................................................................................................................................................................................................................................LLIAWLAGFSSRLF-----AVIRFESIIHEFD-PWFNYRATAYMVQNGWYNF--DERAWYPLWLLHVLNIPVHIRDICVFLAPIFSGLTSISTYLLTKELWSAGAGLFAASFIAIVPGYISRSVAGSYDGIAIFALQFTYFLWVRSWSAAAALSYFYMVSA-IINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLLFSMQIPFVGFQPIRTSEHMAALGVFVLLMAVATLRHLQSVLSRNEFRKLFIVGGLLVGVGVFVAVVVLTMLGVVAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWLHILVCAFPVGVWYCIKQINDERVFVVLYAISAV----------YFAGVMVRLMLTLTPVVCMLAGVAFSGLLDVF 430
13 -9.590[R] COG1287 Uncharacterized membrane protein, required for N-linked glycosylation  ali follow..  9  1......................................................................................................................................................................................................................................................................................................................................................................................................................MANSATITSKKGVKSHQKDWKIPLKVLILICIAVASVSSRLF-----SVIRYESIIHEFD-PWFNFRASKILVEQGFYNFL-DERSWYPVTSGIIFKVLHLLRINVNIRDVAFSGITAIATYYLARELKSDACGLLAAAFMGIAPGYTSRSVAGDNEAIAITLLMSTFALWIKAWGACTGLLYFYMVTA-ITNMIPLHVFVLLLMGRYTSKLYIAYTTYYVIGTLASMQVPFVGFQPVSTSEHMSALGVFGLLQLFAFYNYVKGLVSSKQFQILIRFALVCLVGLATVVLFALSSTGVIAPWTGRFYSLWDTNYAKIHIPIIASVSEHQPPTWLQFLIWLLPVGVYLCFKELRNEHVFIIIYSVLGTYFCG----------VMVRLVLTLTPCVCIAAAVAISTLLDTY 435
14 -9.120[O] COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase  ali follow..  12  17......................................................................................................................................................................................................................................................................................................................................................................................................DLIWRTPIVKEELEDADNFLKDDAELYDKVKNESAVSHLDTIVMPIIFTVLGMFTRMYKIGRNN------HVVWDEAHFGKFGSY----------YLRHEFYHPPLGKMLVGLSGYLAGYNGSWDFAMFSSLCVPLAYFTGRAIGSRLSVWLFTILVIFENSYATLGKFILLDSMLLFFTVSSYFCLAKFHLCLTGLNLGCAISVKMVGLFIISVVGIYTISESDRSVSWKVYVNHWLARIFGLIIIPVCVFLLCFKIHFDL................................................................................................................................................................... 304
15 -9.060[R] KOG1881 Anion exchanger adaptor protein Kanadaptin, contains FHA domain  ali follow..  6  150........................................RAPPYQEPWGG---------------------PATAPYSLETLKG---GTILGTRSLKGTSYCLFGRLSGCDVCL-------------EHPSVSRYHAVLQH-------------RASGPDGECDSNGPGFYL--YD-LGSTHGTFLIPPRTYCRVHVGHVVRF--TRLFILQG------PEEDREAESELTVTQLKELRKQQQILLEKKMLREDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKVLQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKL------NDAERELSEISERLKASSQVLSESPSQDSLDAF----------MSEMKSGSTLDGVSRKKLHLRTFEL--------------RKEQQRLKGLIKIVKPAEIPELKKTETQT........................................................................................................................................................................................................................................................... 593
FFAS is supported by the NIH grant R01-GM087218-01
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Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;