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Query: [S] KOG4030 Uncharacterized conserved protein, contains SPRY domain, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MATSVLCCLRCCRDGGTGHIPLKEMPAVQLDTQHMGTDVVIVKNGRRICGTGGCLASAPLHQNKSYFEFKIQSTGIWGIGVATQKVNLNQIPLGRDMHSLVMRNDGALYHNNEEKNRLPANSLPQEGDVVGITYDHVELNVYLNGKNMHCPASGIRGTVYPVVYVDDSAILDCQFSEFYHTPPPGFEKILFEQQIFLast
1 -87.800[S] KOG4030 Uncharacterized conserved protein, contains SPRY domain  ali  100  1MATSVLCCLRCCRDGGTGHIPLKEMPAVQLDTQHMGTDVVIVKNGRRICGTGGCLASAPLHQNKSYFEFKIQSTGIWGIGVATQKVNLNQIPLGRDMHSLVMRNDGALYHNNEEKNRLPANSLPQEGDVVGITYDHVELNVYLNGKNMHCPASGIRGTVYPVVYVDDSAILDCQFSEFYHTPPPGFEKILFEQQIF 196
2 -39.100[R] KOG3953 SOCS box protein SSB-1, contains SPRY domain  ali follow..  20  64..........................NWTWSKRHRSKEVVLRGPNSRSKGTAGVQGKRSLNNGRHYWELHVSQRTSIMFGIGTKSARLHANALGENEHGWGLSHKGVLWHEGVALLYTK-RFRENQPTQIGVLFDEGTLTFYKDGKCLGVAFRGLDEPLYPIVCSTAAKT.......................... 226
3 -35.000[BK] KOG2626 Histone H3 (Lys4) methyltransferase complex, subunit CPS60/ASH2/BRE2  ali follow..  19  296......................RELLNPTVNVSSNDRAFQLSINGNSITGYSMARASHGVSKGTWYFEVNFDDDSHIRIGWSQSYASLQA-CVGYNKFSYGWRSKHGTKFHEAKGKK-YHFGGFKQGDVLGCLIHGSYIEFFHNGKSCGKAYENIAGAYYPSISIFKSATATMNLGPFRNL-PRGATGIHARAD.. 526
4 -32.200[R] KOG1477 SPRY domain-containing proteins  ali follow..  21  187............................NIDEYGNFLPSFIVQDKLDIQKSSSTVMNYPLPHDAVYFEVKIFRNSIFSIGLTTVPYPYFRVP-GMAKYSIAYESTGKLRINNPFTAS-TLLPKLEEGDTVGFGYRTGTIFITHNGKKLMDVTQNIGIDLFIGIGA-FNAAYTRTYTGLLEDPDN............ 356
5 -31.000[A] KOG2242 Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain  ali follow..  19  193.........RSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPWSGARASYGVRRGRVCFEMKINDPHVVRIGWSLDSCSTQ---LGEEPFSYGYGGTGKKSTNSRFE---NYGDKFAENDVIGCFADDVELSFTKNGKWMGIAFRIQKEALYPHV-LVKNCAVEFNFGAEPYCSVL............ 394
6 -13.200[S] KOG4367 Predicted Zn-finger protein  ali follow..  16  531....................QTSEVAWFAFDPGSAHSDIILSNDNLTVTCSSVVLGKTGFSKGIHYWELTVDRYDDPAFGVARMDVMKDVM-LGKDDKAWAMNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGIAFDNVEGLFFPAVSLNRNVQVTLHTG---LPVPD----YSSRASI. 709
7 -8.210[O] KOG4185 Predicted E3 ubiquitin ligase  ali follow..  6  330..............................DSLTTTHLTIRVNYHLRVQCNYHICTCKFMLISGHIIITSYKSARAYHRGAIISDSEMYRIFLIFSCLVGHLEANCIAKAPMKETIISERSMPLA----VKCSKENPPVEKPEDSRVTGYIQKNFTEGCSIGCKLASGETVPI--GPPQLPVPLFTQNFKCEDT.. 528
8 -8.110[O] KOG2177 Predicted E3 ubiquitin ligase  ali follow..  12  203..........................DFTLQPERDNSHIFLYGDLRSMNECFLVWGAQTFTSGKYYWEVHVGDSWNWAFGVCNNYWKEKRDKIDGEEGLFLLECVKEDTHCSLFTTSPLVVQYVPRP--VGLFLDGEDNEANFGGKNSRKPKKAKEQENQPVNSKSESEQWHM....................... 373
9 -7.680[P] COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport  ali follow..  13  1.......................................MINSPRVCIQVQSVYIEAQSSPDDERYYTVTIRNLGRAPVQLLGRY--------------WLITNGHGRETEVQGEG------------VVG-RIAPGEEYQYTSGAVIETPLGTMQGHY--EMIDENGDAFTIDIPVFRLAVPT............ 122
10 -7.140[P] KOG4408 Putative Mg2+ and Co2+ transporter CorD  ali follow..  12  267............................QIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYF--------TYRIRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPG------------VVG--ISPGRVYEYTSCTTFSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLVS.. 415
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;